KEGG   Cavia porcellus (domestic guinea pig): 100725088
Entry
100725088         CDS       T07777                                 
Symbol
Socs3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc04120  Ubiquitin mediated proteolysis
cpoc04380  Osteoclast differentiation
cpoc04630  JAK-STAT signaling pathway
cpoc04668  TNF signaling pathway
cpoc04910  Insulin signaling pathway
cpoc04917  Prolactin signaling pathway
cpoc04920  Adipocytokine signaling pathway
cpoc04930  Type II diabetes mellitus
cpoc04931  Insulin resistance
cpoc04932  Non-alcoholic fatty liver disease
cpoc04935  Growth hormone synthesis, secretion and action
cpoc05160  Hepatitis C
cpoc05164  Influenza A
cpoc05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    100725088 (Socs3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100725088 (Socs3)
   04668 TNF signaling pathway
    100725088 (Socs3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100725088 (Socs3)
   04920 Adipocytokine signaling pathway
    100725088 (Socs3)
   04917 Prolactin signaling pathway
    100725088 (Socs3)
   04935 Growth hormone synthesis, secretion and action
    100725088 (Socs3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100725088 (Socs3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    100725088 (Socs3)
   05164 Influenza A
    100725088 (Socs3)
   05168 Herpes simplex virus 1 infection
    100725088 (Socs3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100725088 (Socs3)
   04932 Non-alcoholic fatty liver disease
    100725088 (Socs3)
   04931 Insulin resistance
    100725088 (Socs3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:cpoc04121]
    100725088 (Socs3)
Ubiquitin system [BR:cpoc04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     100725088 (Socs3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 100725088
NCBI-ProteinID: XP_013002555
Ensembl: ENSCPOG00000004247
UniProt: H0W4E0
LinkDB
Position
Unknown
AA seq 228 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPSFSSSPTEPASPTEELEQQPPAQPPPGSPPRRAYYIYSGGEKIPLV
LSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 687 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgtcccttggacactagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ttgcaggagagcggtttctactggagtgccgtaaccggcggcgaggcgaacctgctgctc
agcgccgagccggcgggcaccttcctcatccgcgacagttcggaccagcgccacttcttc
acgctgagtgtcaagacccagtccgggacaaagaacctgcgcatccagtgcgagggtggc
agcttctcgttgcagagtgacccgcggagcacgcagcctgtgcctcgcttcgactgcgtg
ctcaaattagtgcaccactacatgccaccccccggtgccccctccttctcctcatcaccg
accgaacccgcctcacccaccgaggagctggagcagcagccacctgcgcagccgcctcca
gggagcccccccaggagagcctattacatctactccggaggcgagaagatccccctggtg
ttgagccggcccctctcctccaacgtcgcaacgctgcagcatctctgccggaagaccgtc
aatggccacctggactcttacgagaaagtcacccagctgcctggacccatccgggagttc
ctggaccaatatgatgccccactttaa

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