Cavia porcellus (domestic guinea pig): 100725667 Help Entry 100725667         CDS       T07777                                  Symbol Adcy3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc00230   Purine metabolism cpoc01100   Metabolic pathways cpoc01522   Endocrine resistance cpoc04015   Rap1 signaling pathway cpoc04020   Calcium signaling pathway cpoc04022   cGMP-PKG signaling pathway cpoc04024   cAMP signaling pathway cpoc04062   Chemokine signaling pathway cpoc04072   Phospholipase D signaling pathway cpoc04081   Hormone signaling cpoc04082   Neuroactive ligand signaling cpoc04114   Oocyte meiosis cpoc04211   Longevity regulating pathway cpoc04213   Longevity regulating pathway - multiple species cpoc04261   Adrenergic signaling in cardiomyocytes cpoc04270   Vascular smooth muscle contraction cpoc04371   Apelin signaling pathway cpoc04540   Gap junction cpoc04611   Platelet activation cpoc04713   Circadian entrainment cpoc04714   Thermogenesis cpoc04723   Retrograde endocannabinoid signaling cpoc04724   Glutamatergic synapse cpoc04725   Cholinergic synapse cpoc04727   GABAergic synapse cpoc04740   Olfactory transduction cpoc04750   Inflammatory mediator regulation of TRP channels cpoc04911   Insulin secretion cpoc04912   GnRH signaling pathway cpoc04913   Ovarian steroidogenesis cpoc04914   Progesterone-mediated oocyte maturation cpoc04915   Estrogen signaling pathway cpoc04916   Melanogenesis cpoc04918   Thyroid hormone synthesis cpoc04921   Oxytocin signaling pathway cpoc04923   Regulation of lipolysis in adipocytes cpoc04925   Aldosterone synthesis and secretion cpoc04926   Relaxin signaling pathway cpoc04927   Cortisol synthesis and secretion cpoc04928   Parathyroid hormone synthesis, secretion and action cpoc04934   Cushing syndrome cpoc04935   Growth hormone synthesis, secretion and action cpoc04962   Vasopressin-regulated water reabsorption cpoc04970   Salivary secretion cpoc04971   Gastric acid secretion cpoc04972   Pancreatic secretion cpoc04976   Bile secretion cpoc05032   Morphine addiction cpoc05163   Human cytomegalovirus infection cpoc05166   Human T-cell leukemia virus 1 infection cpoc05200   Pathways in cancer cpoc05207   Chemical carcinogenesis - receptor activation cpoc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:cpoc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100725667 (Adcy3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100725667 (Adcy3)    04371 Apelin signaling pathway     100725667 (Adcy3)    04020 Calcium signaling pathway     100725667 (Adcy3)    04072 Phospholipase D signaling pathway     100725667 (Adcy3)    04024 cAMP signaling pathway     100725667 (Adcy3)    04022 cGMP-PKG signaling pathway     100725667 (Adcy3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100725667 (Adcy3)    04081 Hormone signaling     100725667 (Adcy3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100725667 (Adcy3)   09144 Cellular community - eukaryotes    04540 Gap junction     100725667 (Adcy3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100725667 (Adcy3)    04062 Chemokine signaling pathway     100725667 (Adcy3)   09152 Endocrine system    04911 Insulin secretion     100725667 (Adcy3)    04923 Regulation of lipolysis in adipocytes     100725667 (Adcy3)    04912 GnRH signaling pathway     100725667 (Adcy3)    04913 Ovarian steroidogenesis     100725667 (Adcy3)    04915 Estrogen signaling pathway     100725667 (Adcy3)    04914 Progesterone-mediated oocyte maturation     100725667 (Adcy3)    04921 Oxytocin signaling pathway     100725667 (Adcy3)    04926 Relaxin signaling pathway     100725667 (Adcy3)    04935 Growth hormone synthesis, secretion and action     100725667 (Adcy3)    04918 Thyroid hormone synthesis     100725667 (Adcy3)    04928 Parathyroid hormone synthesis, secretion and action     100725667 (Adcy3)    04916 Melanogenesis     100725667 (Adcy3)    04925 Aldosterone synthesis and secretion     100725667 (Adcy3)    04927 Cortisol synthesis and secretion     100725667 (Adcy3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100725667 (Adcy3)    04270 Vascular smooth muscle contraction     100725667 (Adcy3)   09154 Digestive system    04970 Salivary secretion     100725667 (Adcy3)    04971 Gastric acid secretion     100725667 (Adcy3)    04972 Pancreatic secretion     100725667 (Adcy3)    04976 Bile secretion     100725667 (Adcy3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     100725667 (Adcy3)   09156 Nervous system    04724 Glutamatergic synapse     100725667 (Adcy3)    04727 GABAergic synapse     100725667 (Adcy3)    04725 Cholinergic synapse     100725667 (Adcy3)    04723 Retrograde endocannabinoid signaling     100725667 (Adcy3)   09157 Sensory system    04740 Olfactory transduction     100725667 (Adcy3)    04750 Inflammatory mediator regulation of TRP channels     100725667 (Adcy3)   09149 Aging    04211 Longevity regulating pathway     100725667 (Adcy3)    04213 Longevity regulating pathway - multiple species     100725667 (Adcy3)   09159 Environmental adaptation    04713 Circadian entrainment     100725667 (Adcy3)    04714 Thermogenesis     100725667 (Adcy3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100725667 (Adcy3)    05207 Chemical carcinogenesis - receptor activation     100725667 (Adcy3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100725667 (Adcy3)    05163 Human cytomegalovirus infection     100725667 (Adcy3)   09165 Substance dependence    05032 Morphine addiction     100725667 (Adcy3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100725667 (Adcy3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100725667 (Adcy3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100725667 (Adcy3) Enzymes [BR:cpoc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100725667 (Adcy3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Motif Other DBs NCBI-GeneID:  100725667 NCBI-ProteinID:  XP_003473206 Ensembl:  ENSCPOG00000005564 UniProt:  H0V5R7 LinkDB All DBs Position Unknown AA seq 1146 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSVSLPSDPERGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLIVAGVGLLLDII LFVLCKKGLLPDRVSRKVVPYLLWLVITAQIFSYLGLNFAHAHAASDTVGWQVFFVFSFF ITLPLSLSPIVTISVVSCVVHTLVLGVTVAQQQQDELQGMQLLREILANVFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGDGGSRCD YLEEKGIETYLVIASRPEVKKTAATQNGLYGSTLPNGAPMSSKPSSPIFIETKEQNGSTH TSGSTSEEPEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERES AQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMT NYVTFVAGEILLLILTVCSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMA NTVDMLSCLQYYTGPHNGTAELQLEGSCLENPKYYSYIAVLALIATIMLVQVSHMVKLTL MLLVTGAAAALSLHTWRPVFDDYDRRRFQEHASPRVASEAVWGLPTLGLNGTDRLPLVPS KYSMTAMIFIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPE HVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISD FDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDRERWQHLADLAD FALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTG VMGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPPAFPNGSSITLPH QVVDSS NT seq 3441 nt NT seq  +upstreamnt  +downstreamnt atgccaaggaaccagggcttctcggatcccgagtactcggcagagtactcggcggagtac tcggtcagcctgccctctgaccccgagcgcggggtgggccggacccatgaaatctccgtc cgcaactcagggtcttgcctgtgtctgcctcgcttcatgcgcctgaccttcgtgcccgag tccttggagaacctgtaccagacctacttcaaaaggcagcgccacgagaccctgctggtg ctggtggtcttcgcggctctgtttgactgctacgtggtggtcatgtgtgctgtggtcttc tccagcgacaagctggctcccctcatcgtggccggggtggggctgctgttggacatcatc ctatttgtactctgcaaaaagggtctgctccctgaccgggtcagccggaaggtggtaccc tacctgctgtggttggtgatcacagcccagatcttctcctacttgggcctgaacttcgcg catgcccacgcggccagcgacacggtgggctggcaggtcttcttcgtcttctccttcttc atcacgctgcccctcagcctcagccccatcgtgaccatctctgtggtctcctgtgttgtg cacacgctggtcttgggggtcaccgtggcccagcagcagcaggatgagctgcaagggatg cagctgctgagagagatcctggccaatgtcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggccgaccggaaacaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaacctcatgctg tccatcctgcccaagcacgtggccgacgagatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccggcacgagaacgtcagcatc ctctttgcagacatcgtgggcttcacccagctgtcatctgcctgcagcgctcaggagctc gtgaagctgctcaacgagctcttcgcccgctttgacaagctggcggccaaataccaccag ctgcggatcaagatcctgggcgactgttactactgcatctgcggcctgcccgactaccgc gaggaccacgccgtgtgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgagaaaagaccaagaccggggtggacatgcgtgtgggggtgcacacgggcaccgtg ctgggcggcgtcctgggccagaagcgctggcagtacgatgtgtggtccactgacgtcact gtggccaacaagatggaggctggcggcatcccagggcgcgtgcacatctcccagagcacc ttggactgtctgaagggagagttcgacgtggagccgggcgacgggggcagccgctgcgat tacctggaggagaagggcatcgagacctacctcgtcatcgcctccaggccggaggtgaag aagacggcggccactcagaatggcctctatggctcgaccctgccaaatggagccccaatg tcctcgaagcccagctcccccatctttattgagaccaaggagcagaatggcagcacccac accagcggctccacatcggaggagcctgaggagcaggaggcccaggcggacaacccctcg ttccccaacccccgccgcaggctgcgcctgcaggacctggctgaccgagtggttgatgcc tccgaggacgagcacgagctcaaccagctgctcaacgaggccctgctggagcgcgagtct gcccaggtcgtgaagaagagaaacacgtttctcctctccatgcggttcatggacccggag atggaaacccgctactcggtggagaaggagaagcagagcggggccgccttcagctgctcc tgcgtggtcctgctctgcaccgccctggtggagatcctcatcgacccctggctgatgaca aactacgtgaccttcgtggccggagagatcctgctgctgatcctgaccgtctgctcgctg gctgccatctttccccgggccttccccaagaagctggtggccttctcaacctggatcgac cggacccgctgggccaggaacacctgggccatgctggccatcttcattctggtcatggca aacaccgtagacatgctcagctgtctgcagtactacacaggaccccacaacgggacggcg gagctgcagctggagggcagctgcctggagaaccccaagtattacagctacatcgccgtg ctggccctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctc atgctgctcgtcacgggcgcggcggccgccctcagcctccacacctggcgccccgtcttt gacgactacgaccgcaggcgctttcaggagcacgcctctcccagggtggcctcagaggcg gtgtggggacttcctaccctggggctcaatggcacagacaggctgcccctcgtgccttcg aagtactcgatgacggcgatgatattcatcatgatgctgagcttctactatttctcccgc cacgtggaaaaactggcccggactctgttcttgtggaagatcgaggtccatgaccagaag gaacgtgtgtacgagatgcggcgctggaacgaggccctggtcaccaacatgctgcccgag cacgtggcacggcatttccttgggtccaagaagagagatgaggagctgtacagccagtcc tatgacgagatcggcgtcatgttcgcctctctgcccaacttcgccgacttctacaccgag gagagcattaacaacggcgggatcgagtgtctgcgcttcctcaacgagatcatctctgac ttcgactcgctcctggacaaccccaaattccgggtcatcaccaagatcaaaaccatcggc agcacctacatggccgcttcaggagtcaccccggacgtgaacaccaatggcttcaccagc tccagcaaggaggagaagtccgaccgggagcgctggcagcacctggccgacctggccgac ttcgcgctcgccatgaaggacacgcttacgaacatcaacaaccagtccttcaacaacttc atgctgcgcataggcatgaacaaaggaggggttctggctggggtcattggagcccgcaaa ccgcactacgacatctggggcaacacagtcaacgtggccagcagaatggagtccacgggg gtgatgggcaacatccaggtggtggaggagacgcaggccatcctgcgggagtacggcttc cgcttcgtgcggcgcgggcccatcttcgtgaagggcaagggcgagctgctgaccttcttc ctgaaggggcgcgaccggccgccggccttccccaacggctcctccatcacactgccccac caggtggtggacagctcctga

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