Cavia porcellus (domestic guinea pig): 100726311
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Entry
100726311 CDS
T07777
Symbol
Ndufs1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00190
Oxidative phosphorylation
cpoc01100
Metabolic pathways
cpoc04714
Thermogenesis
cpoc04723
Retrograde endocannabinoid signaling
cpoc04932
Non-alcoholic fatty liver disease
cpoc05010
Alzheimer disease
cpoc05012
Parkinson disease
cpoc05014
Amyotrophic lateral sclerosis
cpoc05016
Huntington disease
cpoc05020
Prion disease
cpoc05022
Pathways of neurodegeneration - multiple diseases
cpoc05208
Chemical carcinogenesis - reactive oxygen species
cpoc05415
Diabetic cardiomyopathy
Module
cpoc_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
100726311 (Ndufs1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
100726311 (Ndufs1)
09159 Environmental adaptation
04714 Thermogenesis
100726311 (Ndufs1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
100726311 (Ndufs1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100726311 (Ndufs1)
05012 Parkinson disease
100726311 (Ndufs1)
05014 Amyotrophic lateral sclerosis
100726311 (Ndufs1)
05016 Huntington disease
100726311 (Ndufs1)
05020 Prion disease
100726311 (Ndufs1)
05022 Pathways of neurodegeneration - multiple diseases
100726311 (Ndufs1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100726311 (Ndufs1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100726311 (Ndufs1)
Enzymes [BR:
cpoc01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
100726311 (Ndufs1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
100726311
NCBI-ProteinID:
XP_003474229
Ensembl:
ENSCPOG00000005555
UniProt:
H0V5Q8
LinkDB
All DBs
Position
Unknown
AA seq
728 aa
AA seq
DB search
MLRIPLRRALAGLSKSSRAEHVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQ
IPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKTKKAREGVMEF
LLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQC
TRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFT
ARPWETRKTESIDVMDAIGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKR
QRLTEPMVRNEKGLLTHTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALIALKDLLN
RVDSDTLCTEEIFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIR
KSWLHNDLQVALIGSPVDLTYRYNHLGESPKVLQDIASGNHPFSQVLKAAKKPMVVLGSS
ALQRNDGAAILAAVSSIAQEVRVTSGVAGGWKVMNILHRVASQVAALDLGYKPGVEAIRK
TPPRVLFLLGADGGCVTRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSGTYVNT
EGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRSRLEEVSPNLVRYDDV
EGANYFQQASELAKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQ
AVEEPSIC
NT seq
2187 nt
NT seq
+upstream
nt +downstream
nt
atgttgaggatacctcttagaagggccttggcaggcctgtcgaagtcttctagagcggaa
catgttcgaacaaccgccaccgcagccagcaacctgatcgaagtcttcgtcgatggccag
tctgtcatggtggaacctggaaccactgtcctccaggcttgtgaaaaggttggcatgcag
atcccgcgcttctgctaccatgaaaggctgtccgttgctggtaactgcaggatgtgcctc
gttgaaattgagaaggcccctaaggtcgtggctgcttgtgctatgcctgtaatgaaaggt
tggaatatcctgacaaactcggaaaaaactaagaaagccagagaaggtgtgatggagttt
ttattagcaaatcacccattggactgtcctatttgtgaccagggaggtgaatgtgatctg
caggaccagtccatgatgttcggaagtgatagaagccgatttttagaggggaagcgtgct
gtggaggacaagaacatcggccccttagtgaagaccatcatgaccagatgcattcagtgt
acgcggtgcatcaggtttgcaagtgagattgcgggagtggatgatttgggaacaacaggc
cgaggaaatgatatgcaagttggcacatacattgaaaaaatgttcatgtctgaattatct
gggaacatcattgacatctgtcctgtgggtgccctaacctcgaagccctatgccttcacc
gcccgcccgtgggagacaagaaagacagagtctattgatgtcatggatgcaattgggagt
aacatcgtggtcagcaccagaacgggggaggtgatgcggatcctgccacgcatgcacgag
gacatcaatgaggagtggatctctgataagaccagatttgcctatgacgggctgaagcgt
cagagactcactgagccgatggtccgaaatgaaaagggactcttaacccacacctcctgg
gaggacgcgctgtcccgtgtagctggcatgctgcagagttttcaaggcaaggatgtggca
gcaattgcaggtggcctggtggatgctgaggccctgatagccctgaaggatttgctgaac
cgagtggactctgacaccctgtgcacggaggagatcttccccactgcgggtgctggaaca
gatttgcgttccaattatcttcttaatactacaattgctggtgtggaagaggcagatgtt
gtccttctggtcggtacaaatccacgttttgaggcgccactctttaatgccagaattcgg
aagagttggcttcataacgacttacaagtggccctcataggcagtccagtggacctcacg
tacagatacaaccacctgggcgagtcccccaaagttctgcaagacattgcttcaggaaac
catccattcagccaggtcttaaaagcagccaaaaaaccaatggtggttttaggcagctct
gcactccagagaaacgatggcgcagcaattctcgctgctgtttccagcattgcacaggag
gtccgggtgacaagtggtgtggctggcggttggaaggttatgaatatcctgcacagggtt
gcgagccaggtagctgctctggacctgggctataagcctggggtagaagcgattcggaag
accccccccagagtgctgttcctgctaggagcagatggcggttgtgtcacacgacaggat
ttgccaaaggattgtttcatcatttaccaagggcatcatggtgatgtgggtgctcccatc
gctgatgtcattctccctggagctgcttacacagagaagtcaggcacttatgttaacact
gagggcagagctcagcagaccaaagtggcggtgacaccgcccggcttggcaagagaagac
tggaaaattatccgagctctctctgagattgcgggtatgactctcccgtatgacacactg
gaccaggtgaggagcagattggaagaagtctcccctaaccttgttcgatatgatgatgtt
gaaggagcaaattactttcagcaagcaagtgagctcgccaagctggtgaaccagcagctt
cttgctgacccactcgttccacctcagctgactataaaagacttctacatgaccgattcc
atcagcagagcttcacagacaatggccaagtgtgtgaaggctgtcacggagggtgcccag
gccgtggaggagccgtccatatgctga
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