Cavia porcellus (domestic guinea pig): 100726398 Help Entry 100726398         CDS       T07777                                  Symbol Sos2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc01521   EGFR tyrosine kinase inhibitor resistance cpoc01522   Endocrine resistance cpoc04010   MAPK signaling pathway cpoc04012   ErbB signaling pathway cpoc04014   Ras signaling pathway cpoc04062   Chemokine signaling pathway cpoc04068   FoxO signaling pathway cpoc04072   Phospholipase D signaling pathway cpoc04150   mTOR signaling pathway cpoc04151   PI3K-Akt signaling pathway cpoc04510   Focal adhesion cpoc04540   Gap junction cpoc04630   JAK-STAT signaling pathway cpoc04650   Natural killer cell mediated cytotoxicity cpoc04660   T cell receptor signaling pathway cpoc04662   B cell receptor signaling pathway cpoc04664   Fc epsilon RI signaling pathway cpoc04714   Thermogenesis cpoc04722   Neurotrophin signaling pathway cpoc04810   Regulation of actin cytoskeleton cpoc04910   Insulin signaling pathway cpoc04912   GnRH signaling pathway cpoc04915   Estrogen signaling pathway cpoc04917   Prolactin signaling pathway cpoc04926   Relaxin signaling pathway cpoc04935   Growth hormone synthesis, secretion and action cpoc05034   Alcoholism cpoc05160   Hepatitis C cpoc05161   Hepatitis B cpoc05163   Human cytomegalovirus infection cpoc05165   Human papillomavirus infection cpoc05200   Pathways in cancer cpoc05205   Proteoglycans in cancer cpoc05206   MicroRNAs in cancer cpoc05207   Chemical carcinogenesis - receptor activation cpoc05208   Chemical carcinogenesis - reactive oxygen species cpoc05210   Colorectal cancer cpoc05211   Renal cell carcinoma cpoc05213   Endometrial cancer cpoc05214   Glioma cpoc05215   Prostate cancer cpoc05220   Chronic myeloid leukemia cpoc05221   Acute myeloid leukemia cpoc05223   Non-small cell lung cancer cpoc05224   Breast cancer cpoc05225   Hepatocellular carcinoma cpoc05226   Gastric cancer cpoc05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:cpoc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100726398 (Sos2)    04012 ErbB signaling pathway     100726398 (Sos2)    04014 Ras signaling pathway     100726398 (Sos2)    04630 JAK-STAT signaling pathway     100726398 (Sos2)    04068 FoxO signaling pathway     100726398 (Sos2)    04072 Phospholipase D signaling pathway     100726398 (Sos2)    04151 PI3K-Akt signaling pathway     100726398 (Sos2)    04150 mTOR signaling pathway     100726398 (Sos2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100726398 (Sos2)    04540 Gap junction     100726398 (Sos2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100726398 (Sos2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100726398 (Sos2)    04660 T cell receptor signaling pathway     100726398 (Sos2)    04662 B cell receptor signaling pathway     100726398 (Sos2)    04664 Fc epsilon RI signaling pathway     100726398 (Sos2)    04062 Chemokine signaling pathway     100726398 (Sos2)   09152 Endocrine system    04910 Insulin signaling pathway     100726398 (Sos2)    04912 GnRH signaling pathway     100726398 (Sos2)    04915 Estrogen signaling pathway     100726398 (Sos2)    04917 Prolactin signaling pathway     100726398 (Sos2)    04926 Relaxin signaling pathway     100726398 (Sos2)    04935 Growth hormone synthesis, secretion and action     100726398 (Sos2)   09156 Nervous system    04722 Neurotrophin signaling pathway     100726398 (Sos2)   09159 Environmental adaptation    04714 Thermogenesis     100726398 (Sos2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100726398 (Sos2)    05206 MicroRNAs in cancer     100726398 (Sos2)    05205 Proteoglycans in cancer     100726398 (Sos2)    05207 Chemical carcinogenesis - receptor activation     100726398 (Sos2)    05208 Chemical carcinogenesis - reactive oxygen species     100726398 (Sos2)    05231 Choline metabolism in cancer     100726398 (Sos2)   09162 Cancer: specific types    05210 Colorectal cancer     100726398 (Sos2)    05225 Hepatocellular carcinoma     100726398 (Sos2)    05226 Gastric cancer     100726398 (Sos2)    05214 Glioma     100726398 (Sos2)    05221 Acute myeloid leukemia     100726398 (Sos2)    05220 Chronic myeloid leukemia     100726398 (Sos2)    05211 Renal cell carcinoma     100726398 (Sos2)    05215 Prostate cancer     100726398 (Sos2)    05213 Endometrial cancer     100726398 (Sos2)    05224 Breast cancer     100726398 (Sos2)    05223 Non-small cell lung cancer     100726398 (Sos2)   09172 Infectious disease: viral    05161 Hepatitis B     100726398 (Sos2)    05160 Hepatitis C     100726398 (Sos2)    05163 Human cytomegalovirus infection     100726398 (Sos2)    05165 Human papillomavirus infection     100726398 (Sos2)   09165 Substance dependence    05034 Alcoholism     100726398 (Sos2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100726398 (Sos2)    01522 Endocrine resistance     100726398 (Sos2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH RHG20_PH IQ_SEC7_PH PH_13 Motif Other DBs NCBI-GeneID:  100726398 NCBI-ProteinID:  XP_003471855 Ensembl:  ENSCPOG00000010690 UniProt:  A0A286X9C8 LinkDB All DBs Position Unknown AA seq 1327 aa AA seqDB search MQQAPQPYEFFSEENSPKWRGLLVAALRKVQEQVHPTLSAHEESLYYIEELIFQLLSKLC MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD DIGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFIFDRKLFKPSD IEKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLAQD ILSPAYNEHFSKLMARPAVALHFQSIAEGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLK ACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCPFYNRQLRSKHLAIKK MNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRLP GYSNAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIFAAKSAEEKNNWMAAL ISLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYCFVVKDSEENIVFEDNLQSRSGIPII KGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKL AMEKGEQPISVDLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLESFISSV RGKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQLETFELMTLHP IEVARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVE AENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKIL DEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKELINFSKR RKVAEITGEIQQYQNQPYCLRIELEMRRFFENLNPMGNSSEKEFTDYLFNKSLEIEPRNC KQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPYKISFSRIAETELEST VSAPTSPNTPSTPPVSASSDVSVFLDVDLNSSCGNNSIFAPVLLPQSKSFFSSCGSLNKL NEEPLVPPPLPPRKKFDHDASNPKGTMKSDDDPPAIPPRQPPPPKVKPRVPVPTGALDGP LHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDVSTCPNSPSTPPST PSPRVPRRCYVLSSSHNSLVHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLYRLPLL ENAETPQ NT seq 3984 nt NT seq  +upstreamnt  +downstreamnt atgcagcaggcgccgcagccgtacgagttcttcagcgaggagaacagcccgaaatggcgg ggactgctggtcgcggccctgcggaaggttcaggagcaagtgcatccaactctctcagct catgaagagtctctctattacattgaagaactgatttttcagctgctaagtaaattatgc atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat ccaattgataaatgggctattgcggatgcacaatctgccatagaaaaacgaaagcgaaga aatcctcttttattgcctgtagacaaaatccatccttctttgaaggaagttttggggtat aaagtggactaccatgtgtccctgtatattgtggctgtactggagtatatctcagcagat attttaaaattggctggtaattatgtttttaatatccgacattatgaaatatctcagcag gacatcaaagtatcgatgtgtgcagataaggttttgatggacatgtttgatcaggatgat gatataggtttggtttctctatgtgaagatgaacctagttcctctggtgaattaaactat tacgaccttgtcagaactgaaattgcagaagaaagacagtatcttcgggaactgaacatg atcataaaagtgtttcgagaagcctttatttttgacagaaagttatttaaaccttctgat attgaaaagatttttagtaacattttagacatacatgaattgactgtgaaacttttaggt ttgattgaagacacagttgaaatgacagatgaaagcagccctcatcccttagctggcagc tgttttgaggatttggcagaagagcaagcatttgatccctatgaaacattagcacaggac attctttcaccagcgtataatgaacatttcagtaagctgatggccagacctgcagttgct ctacactttcagtccattgctgaaggctttaaagaggcagttcgctatgtacttccacgc cttatgttggtgccagtatatcattgttggcattattttgaattattaaagcaattgaaa gcatgtagtgaagagcaagaagacagagaatgtttgaatcaagctatcactgctctcatg aatctccagggtagcatggaccggatttataagcagcattctccgcgacgccggcctggg gatcctgtttgccctttttataatcgtcaattaagaagcaagcacctggctatcaaaaaa atgaatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgt aatgaattcataatggaaggaccgttgacaagaattggtgctaaacatgaacggcacatt tttctgtttgatggactaatgatcagctgtaaacctaatcatggccagactcggcttcca ggttatagtaatgcagaatatagattaaaagaaaagtttgtcatgaggaaaatacaaatc tgtgataaagaagatacttgtgagtgcaaacatgcctttgaattagtatccaaagatgaa aacagcataatatttgctgctaagtctgctgaagagaaaaataattggatggcagcactt atttctcttcattatcgtagtactctagatcgaatgctagattctgtgttattgaaagaa gaaaatgagcagccactgagattgccaagtccagaagtgtattgttttgtggtaaaagac tctgaggagaacattgtttttgaagacaatttgcaaagtagaagtggaatccccattatt aaaggaggaactgtggtgaagttaattgagaggttaacatatcatatgtatgcagatccc aattttgttcgtacttttcttactacatatcgatcattttgtaagccacaggaattgcta agcttactgattgaacgatttgaaatcccggagccagaacctactgaagcagacaaattg gcaatggagaaaggcgagcagccaatcagtgtggacctaaaaagatttcgcaaggaatat gttcaaccagtacaacttagggtcttaaatgtttttcggcactgggttgaacaccatttt tatgactttgaaagagatttggaattgcttgaaagactagaatccttcatttcaagtgta agagggaaagccatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaa caagctcaggcaaatggaataagccataatattacctttgagagtccacctccgcccatt gagtggcacatcagtaggcctggacagctagagacgtttgagcttatgacccttcatcca atagaagtcgcacgtcagctaacacttttggaatctgatctgtacagaaaagtccaacct tctgaacttgtagggagtgtgtggaccaaagaagataaagaaataaattctccaaattta ttgaaaatgattcgccataccacaaatctcactctctggttcgaaaaatgcattgtggaa gcagaaaattttgaagaacgagtggcagtattaagtagaattatagaaattctgcaagtt tttcaagatttgaataatttcaatggcgtattggagatagtcagtgccgtaaattcagtg tcagtgtacagactagaccacacctttgaggcattgcaggaaagaaaacggaaaattttg gatgaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaactaaagtca attaatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagaccgaa gaagggaataatgattttttaaaaaagaaagggaaagagctaatcaatttcagtaaaagg aggaaagtagctgaaattactggagaaattcaacagtatcagaatcaaccttactgttta cgcatagaactagaaatgaggaggttcttcgaaaatcttaatcccatgggaaattcatct gaaaaagagtttacagattatttgttcaacaagtcactagaaattgaacccagaaattgt aaacagccacctcgatttcctaggaaatcaactttctccttaaaatctcctggaataagg cctaatacaggccgacatggctctacctcaggcactttacgaggtcatcctacaccattg gaaagagaaccatacaagataagctttagtcggattgctgaaactgagcttgaatcaaca gtgtcagcaccaacctctccaaatacgccatctactccgccagtttctgcttcttcagac gttagtgtgtttttagatgtggatctcaatagttcctgtggcaataatagcatctttgct ccagtgctcttgccacaatcaaagtctttcttcagttcgtgtggtagcttaaataaacta aatgaagagccactggttcctcctcctcttcctcctcgaaagaagtttgatcatgatgct tcaaatcctaagggaactatgaaatcagatgatgaccctcctgcgattccaccaagacag cctcctcctccaaaggtaaaacccagagttcctgttcctactggtgcacttgatgggcct ctgcatagtccgcctccaccaccgccaagagatcctcttcctgacacccctcctccagtt ccccttcggcctccagaacactttataaactgtccgtttaatcttcagccacctccactg ggacatcttcacagagacgttagtacgtgtcccaattcgccaagcactcctcctagcaca ccctctccacgggtgccgcgtcgatgctatgtgctcagttcgagtcacaacagtctggtt catcctccagctccccctgttcctccacggcaaaattcaagccctcatctaccaaaactg ccaccaaagacttacaagcgggagctttcacaccccccgttgtacagactgcctttgcta gaaaatgcagaaactcctcaatga

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