KEGG   Cavia porcellus (domestic guinea pig): 100728704
Entry
100728704         CDS       T07777                                 
Symbol
Cltc
Name
(RefSeq) clathrin heavy chain 1 isoform X2
  KO
K04646  clathrin heavy chain
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc04142  Lysosome
cpoc04144  Endocytosis
cpoc04721  Synaptic vesicle cycle
cpoc04961  Endocrine and other factor-regulated calcium reabsorption
cpoc05016  Huntington disease
cpoc05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100728704 (Cltc)
   04142 Lysosome
    100728704 (Cltc)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100728704 (Cltc)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    100728704 (Cltc)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100728704 (Cltc)
  09164 Neurodegenerative disease
   05016 Huntington disease
    100728704 (Cltc)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cpoc04131]
    100728704 (Cltc)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cpoc04147]
    100728704 (Cltc)
Membrane trafficking [BR:cpoc04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Clathrin
    100728704 (Cltc)
Exosome [BR:cpoc04147]
 Exosomal proteins
  Proteins found in most exosomes
   100728704 (Cltc)
SSDB
Motif
Pfam: Clathrin Clathrin_propel Clathrin_H_link Clathrin-link TPR_COPA_B TPR_PEP5_VPS11 TPR_Vps41 TPR_1
Other DBs
NCBI-GeneID: 100728704
NCBI-ProteinID: XP_003469497
Ensembl: ENSCPOG00000005508
UniProt: A0A286X7P2
LinkDB
Position
Unknown
AA seq 1675 aa
MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSN
PIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVA
LVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGA
MQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGN
QPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISG
ETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGA
EELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGI
LLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYL
RANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDE
EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAIL
GNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSV
EDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVN
FSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDR
FDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQF
STDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYY
DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVL
LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE
HRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTS
AVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEV
VQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQ
VGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFAC
VDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL
AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMN
HPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFS
KVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLE
KHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQE
EKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLR
KEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQPGFGYSM
NT seq 5028 nt   +upstreamnt  +downstreamnt
atggcccagattcttccaattcgttttcaggagcatctccagctccagaacctgggtatt
aacccagcaaacattggcttcagtaccctgactatggaatcagacaaattcatctgcatt
agagaaaaagtcggagagcaggctcaggtggtaatcattgatatgaatgatccaagtaat
cccattcgaagaccaatttcagcagacagtgccatcatgaatccagctagcaaagtaatt
gcattaaaagctgggaaaactcttcagatatttaacattgaaatgaaaagtaaaatgaag
gcccataccatgactgatgatgtcacattttggaaatggatctctttgaatacggttgcc
cttgttacggataatgcagtttatcattggagtatggaaggagagtcccagccagtgaaa
atgtttgatcgtcattctagccttgcaggatgccagattattaactatcgcacagacgca
aagcagaagtggctacttctgactggtatatctgcacagcaaaatcgtgtggtgggagct
atgcagctatattctgtagatagaaaagtgtctcagcccattgaaggacatgcggctagc
tttgcacaatttaagatggaaggaaatgcagaagaatcaacgttattttgttttgcagta
cggggtcaagctggaggaaagttacatattattgaagttggcacaccacctacagggaac
cagccctttccaaagaaggcggtggatgttttctttcctccagaagcacaaaatgacttt
cctgttgcaatgcagatcagtgaaaagcatgatgtggtgttcttgattaccaagtatggt
tatatccatctctatgatcttgaaactggtacttgcatctatatgaacagaattagtgga
gaaacaatttttgttactgcacctcatgaagcgacagctggaataattggagtgaaccga
aaaggacaagttttgtcagtgtgtgtggaagaggaaaacataattccatatatcaccaat
gtgctacaaaatcccgatttggctctgagaatggctgtacgtaacaatttagctggtgct
gaagaactctttgctcggaaatttaatgctctttttgctcaaggaaattactcagaggct
gcaaaagtggctgctaatgcaccaaagggaattcttcgcactccagacaccatccgacgg
ttccagagtgttcctgctcaaccaggtcagacttcacctctccttcagtactttggaatc
cttctggaccaaggccagctgaacaaatatgaatccttagagctgtgtaggcctgttctt
cagcaagggcggaaacagcttttggagaagtggttgaaagaagataaacttgaatgttct
gaagaattgggggatcttgtgaaatctgtggatcctacattagcacttagtgtgtacctg
agggctaatgtcccaaataaggtcattcagtgctttgcagaaacaggtcaagttcagaag
attgttttatatgctaaaaaagttggatatactccagactggatctttctgctgagaaac
gtgatgcgtatcagtccagatcagggacagcagtttgcccaaatgttagttcaagatgaa
gagcctcttgctgatatcacacagattgtggatgtctttatggaatacaaccttatccaa
caatgtacagcattcctgcttgatgctctgaaaaataatcgcccatctgagggtccttta
cagacacggttgcttgagatgaatcttatgcatgcaccccaagttgcagatgccatttta
gggaatcagatgtttacacattatgatcgggctcatatcgctcagctgtgtgaaaaggct
ggcctgttgcagcgtgcattagagcacttcactgatttatatgacataaagcgtgcagtt
gttcatacacatcttcttaaccctgagtggttagttaattactttggatccttatcagtg
gaggactcgctagaatgtctcagagccatgctgtctgctaatattcgtcagaatctgcag
atttgtgttcaagtggcatccaagtaccatgaacagctttcaactcaatctctgattgaa
ctttttgaatctttcaagagttttgaaggtctcttttattttctgggatccattgttaac
ttcagtcaagacccagacgtacattttaaatatattcaggcagcttgtaagactgggcag
atcaaagaagtagaaagaatctgcagagaaagcaactgctatgatcctgaacgagtcaag
aattttctcaaggaagcaaaactaacagatcagttgccacttattattgtgtgtgatcga
tttgatttcgtccatgacttggtgctatatttatatcggaataatcttcaaaaatatata
gaaatatatgtacagaaggtgaatccaagtcgacttcctgtggttattggaggattactt
gatgttgactgctctgaagatgtcattaaaaacttgattcttgttgtgagaggtcaattc
tctactgatgagctagttgctgaggttgaaaaaagaaacagactgaaactgcttctgcct
tggctagaagccagaattcatgagggttgtgaggagcctgctactcacaatgcattagcc
aaaatctacattgacagtaataacaacccagagagatttcttcgtgaaaacccttattac
gacagtcgtgttgttggcaagtattgtgagaagagagatccacatctggcctgtgttgct
tatgaacgtggccagtgtgatctagaacttattaatgtttgcaatgagaattctctcttc
aaaagtctttcccgctatttggtacgccgaaaggatccagaattgtggggtagtgtgcta
ctggaaagcaatccttataggagacccctaattgatcaggttgtacaaacagccttgtct
gagactcaagaccctgaagaagtgtcggtaactgttaaagcttttatgactgcagacctt
cctaatgaactcattgaactgctggagaaaatcgtccttgataactctgtattcagtgaa
cacaggaatctgcaaaacctcctcatcctcactgcaattaaagctgaccgtacacgtgtt
atggagtatattaaccgcctggataattatgatgcccctgacattgccaatattgctata
agcaatgagctgtttgaagaagcatttgctattttccggaagtttgatgtcaacacttca
gcagtgcaggtcttgattgaacatattggaaacttggatcgggcatatgagtttgctgaa
cgctgcaatgaacctgcagtatggagtcaactagcgaaagcccagttgcagaaaggaatg
gtgaaagaagccatcgattcttacatcaaagcagatgatccttcatcctacatggaggtt
gttcaggctgccaataccagtggaaactgggaagaactggtgaagtacttgcaaatggct
cgaaagaaggctcgagaatcttacgtggagacagaattgatattcgcactggctaaaaca
aaccgccttgcagagttagaagaattcatcaatggaccaaataatgctcatatccaacaa
gttggtgaccgttgttatgatgaaaaaatgtatgatgctgctaagttgttgtacaacaat
gtttctaattttggtcgcttggcatctaccctggttcatctgggtgaatatcaggcagct
gttgatggagctaggaaagccaacagtactcgaacatggaaagaggtctgctttgcttgt
gtagatgggaaagagttccgtcttgctcagatgtgtggacttcacattgtagtacatgca
gatgaactagaggaacttatcaactactatcaggatcgtggatattttgaagaattgata
accatgttggaagcagcattgggacttgagcgagctcacatgggaatgtttactgaattg
gctatcctgtattctaaatttaagccacagaaaatgagggagcatctggagcttttctgg
tccagagtaaatattcctaaggtgctaagagctgcagaacaagctcatttatgggcagaa
ctagtgtttttgtatgacaagtatgaagaatatgataatgccataattaccatgatgaat
catccaactgatgcatggaaagaagggcagtttaaagatattattaccaaggttgccaat
gtggaactatattacagagcaatacagttctatttagaattcaagcctctgttgttaaac
gatctgctgatggtgctgtctccacgattggatcatactcgtgcagtcaattatttcagc
aaagttaaacagctgccattggtcaaaccatatttgcgttcagttcagaatcacaacaac
aaatctgtgaatgaatcactgaacaacctttttattacagaagaagattatcaggctctg
cgaacatcaatagatgcttatgacaactttgacaatatttcacttgctcaacgtttggaa
aaacatgaactcattgagtttagaagaattgctgcttatctcttcaaaggcaacaatcgt
tggaaacagagtgtagagctgtgcaagaaagacagcctttacaaggatgcaatgcagtat
gcctctgaatcaaaagatactgagttggctgaagaactcctgcagtggtttttgcaggaa
gaaaaaagagagtgctttggagcttgtctgttcacttgttatgatctcttaagaccagat
gttgtcttggaaactgcatggaggcacaacatcatggattttgcaatgccctatttcatc
caggtcatgaaggaatatttgaccaaggtggataaattagatgcttcagaatcactgaga
aaagaagaagaacaagctacagagacacaacccattgtttatggtcagccccagctgatg
ctcacagcaggacctagtgttgcagtccctccccaggcacctttcggttatggttatacc
gcaccaccatatgggcagccacagcctggctttgggtacagcatgtga

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