Cavia porcellus (domestic guinea pig): 100728974
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Entry
100728974 CDS
T07777
Symbol
Ppp3ca
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
KO
K04348
serine/threonine-protein phosphatase 2B catalytic subunit [EC:
3.1.3.16
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc04010
MAPK signaling pathway
cpoc04020
Calcium signaling pathway
cpoc04022
cGMP-PKG signaling pathway
cpoc04114
Oocyte meiosis
cpoc04218
Cellular senescence
cpoc04310
Wnt signaling pathway
cpoc04360
Axon guidance
cpoc04370
VEGF signaling pathway
cpoc04380
Osteoclast differentiation
cpoc04625
C-type lectin receptor signaling pathway
cpoc04650
Natural killer cell mediated cytotoxicity
cpoc04658
Th1 and Th2 cell differentiation
cpoc04659
Th17 cell differentiation
cpoc04660
T cell receptor signaling pathway
cpoc04662
B cell receptor signaling pathway
cpoc04720
Long-term potentiation
cpoc04724
Glutamatergic synapse
cpoc04728
Dopaminergic synapse
cpoc04921
Oxytocin signaling pathway
cpoc04922
Glucagon signaling pathway
cpoc04924
Renin secretion
cpoc05010
Alzheimer disease
cpoc05014
Amyotrophic lateral sclerosis
cpoc05020
Prion disease
cpoc05022
Pathways of neurodegeneration - multiple diseases
cpoc05031
Amphetamine addiction
cpoc05152
Tuberculosis
cpoc05163
Human cytomegalovirus infection
cpoc05166
Human T-cell leukemia virus 1 infection
cpoc05167
Kaposi sarcoma-associated herpesvirus infection
cpoc05170
Human immunodeficiency virus 1 infection
cpoc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cpoc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100728974 (Ppp3ca)
04310 Wnt signaling pathway
100728974 (Ppp3ca)
04370 VEGF signaling pathway
100728974 (Ppp3ca)
04020 Calcium signaling pathway
100728974 (Ppp3ca)
04022 cGMP-PKG signaling pathway
100728974 (Ppp3ca)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
100728974 (Ppp3ca)
04218 Cellular senescence
100728974 (Ppp3ca)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
100728974 (Ppp3ca)
04650 Natural killer cell mediated cytotoxicity
100728974 (Ppp3ca)
04660 T cell receptor signaling pathway
100728974 (Ppp3ca)
04658 Th1 and Th2 cell differentiation
100728974 (Ppp3ca)
04659 Th17 cell differentiation
100728974 (Ppp3ca)
04662 B cell receptor signaling pathway
100728974 (Ppp3ca)
09152 Endocrine system
04922 Glucagon signaling pathway
100728974 (Ppp3ca)
04921 Oxytocin signaling pathway
100728974 (Ppp3ca)
04924 Renin secretion
100728974 (Ppp3ca)
09156 Nervous system
04724 Glutamatergic synapse
100728974 (Ppp3ca)
04728 Dopaminergic synapse
100728974 (Ppp3ca)
04720 Long-term potentiation
100728974 (Ppp3ca)
09158 Development and regeneration
04360 Axon guidance
100728974 (Ppp3ca)
04380 Osteoclast differentiation
100728974 (Ppp3ca)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100728974 (Ppp3ca)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100728974 (Ppp3ca)
05170 Human immunodeficiency virus 1 infection
100728974 (Ppp3ca)
05163 Human cytomegalovirus infection
100728974 (Ppp3ca)
05167 Kaposi sarcoma-associated herpesvirus infection
100728974 (Ppp3ca)
09171 Infectious disease: bacterial
05152 Tuberculosis
100728974 (Ppp3ca)
09164 Neurodegenerative disease
05010 Alzheimer disease
100728974 (Ppp3ca)
05014 Amyotrophic lateral sclerosis
100728974 (Ppp3ca)
05020 Prion disease
100728974 (Ppp3ca)
05022 Pathways of neurodegeneration - multiple diseases
100728974 (Ppp3ca)
09165 Substance dependence
05031 Amphetamine addiction
100728974 (Ppp3ca)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100728974 (Ppp3ca)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
cpoc01009
]
100728974 (Ppp3ca)
Enzymes [BR:
cpoc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
100728974 (Ppp3ca)
Protein phosphatases and associated proteins [BR:
cpoc01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Catalytic subunits
100728974 (Ppp3ca)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Metallophos
Motif
Other DBs
NCBI-GeneID:
100728974
NCBI-ProteinID:
XP_003468072
Ensembl:
ENSCPOG00000009843
LinkDB
All DBs
Position
Unknown
AA seq
533 aa
AA seq
DB search
MKPKDSTLGQVADVLVPPGLAAVVGAASAAIAVPFPPSHRLTAKEVFDNDGKPRVDILKA
HLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSP
ANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKI
KYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMC
DILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGY
RMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMD
VFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMAR
VFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKIT
SFEEAKGLDRINERMPPRRDAVPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgaagcccaaagattccactctggggcaggtggctgacgtgctggttcctccagggtta
gcagctgtggtgggggcagcctctgcagccatagctgttccctttcctccaagtcaccgg
ctcacagcaaaggaagtgtttgacaatgatgggaaacctcgagtggatatcctaaaagca
catctcatgaaggagggccggctggaagagagtgtggcattgaggataataacagagggt
gcttcgattctgcgacaggagaagaacttgctggacatcgatgcgcccgtcacagtttgt
ggggacatccatggacaattttttgacttgatgaagctcttcgaagtggggggatctcct
gccaacactcgctacctctttctgggggactacgttgacagaggatacttcagcattgag
tgtgtgctgtatttgtgggccttgaaaattctttaccctaaaacactgtttttacttcgt
ggaaatcatgaatgtagacatctaacagagtatttcacatttaaacaagaatgtaaaata
aagtactcggagcgcgtctatgacgcctgcatggacgccttcgactgcctgcccctggcc
gccctgatgaaccagcagttcctgtgcgtgcacggcgggctgtccccagagatcaacaca
ctggacgacatcaggaaattagaccgattcaaagaaccacctgcttatgggcccatgtgt
gacatcctgtggtcggaccccctggaggacttcgggaacgagaagactcaggaacatttc
acccacaatacagtccgggggtgttcgtacttctacagttacccagctgtctgtgaattc
ttgcagcacaataacttgttatccatactccgagcccatgaagcccaggatgcagggtat
cgcatgtacaggaaaagccaaacaacaggcttcccttctctaattacaattttttcagca
ccaaattacttagatgtatacaataacaaagccgcggtattaaagtacgaaaacaatgtc
atgaacatcaggcagttcaactgttccccacacccatactggctcccgaacttcatggac
gtcttcacctggtctctgccgttcgtcggggaaaaagtgactgagatgctggtcaatgtc
ctcaacatctgctctgatgatgaacttgggtcagaagaggacggctttgatggagccacg
gcagcggcccgaaaggaggtgattcggaacaagatccgcgccatcgggaagatggccagg
gtgttctcagttctcagagaggagagcgagagcgtgctgacactgaagggcctgaccccc
accggcatgctgcccagtggcgtactctcaggaggcaagcagaccctgcaaagcgctact
gttgaggctattgaggctgatgaagctatcaaaggcttctcgccccagcataagatcact
agcttcgaggaggccaagggcttagaccggattaatgagaggatgccaccccgccgagat
gccgtaccctcggacgccaacctcaactctatcaacaaggccctcgcctcagagactaac
ggcacggacagcaacggcagcaacagcagcaatattcagtga
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