Cavia porcellus (domestic guinea pig): 100729412
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Entry
100729412 CDS
T07777
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00230
Purine metabolism
cpoc00670
One carbon pool by folate
cpoc01100
Metabolic pathways
cpoc01523
Antifolate resistance
Module
cpoc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100729412 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100729412 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100729412 (Gart)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
100729412 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
100729412 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
100729412 (Gart)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
GARS_C
AIRS
AIRS_C
ATP-grasp
CPSase_L_D2
ATP-grasp_4
Dala_Dala_lig_C
ATP-grasp_2
ATP-grasp_3
ATP-grasp_LDMS
DiatomPyrShell
LUD_dom
RimK
ATP-grasp_5
STING_LBD
Motif
Other DBs
NCBI-GeneID:
100729412
NCBI-ProteinID:
XP_012997296
Ensembl:
ENSCPOG00000005160
LinkDB
All DBs
Position
Unknown
AA seq
990 aa
AA seq
DB search
MAARILVIGSGGREHTLAWKLGQSHHVQQVLVAPGNAGTACSGKISNTAISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGDLTSAGVRCFGPNAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKAEEACGFIMRADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GAAGETIVVEELLEGEEVSCMCFTDGRTVVPMPPAQDHKRLLEGDLGPNTGGMGAYCPAP
QVSKDLLLKIKNTVLQRTVDGMQQEGTPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEMIQSTLDGSLGASPPIWLDDHTAVTVVMASKGYPGAYTKGMEITGFPEA
QALGLEVFHAGTALKDGKVVTSGGRVLTVTAVRENLKLALEEAQKGLAVIKFEGAVYRKD
IGFRAIAFLQQPRGLTYKGSGVDIEAGNMLVKKIQPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHSTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSTTEAVIAGVSEACKEAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDEKLP
HLEQIVEEDTIVGIASSGLHSNGFSLVRKIVAQSSLEYSSPAPAGCGDQTLGDLLLTPTR
IYSRSLLPVIRSGHLDSSCLFPDARTWRIPRVFSWLQQEGQLSEEEMARTFNCGVGAALV
VSKSQTEQILREIQQRQEEAWVIGSVVACPKGSPRVKVKNLIEAMQMNGSVLVNGSLKTH
FPAQPTKARVAVLISGTGSNLQALIDSTQDPNSSADIVVVISNKAAVAGLNKAERAGIPT
RVINHKLYKNREEFDNAIDQVLEEFSTDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLP
SFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSEKVKVAE
HKIFPKALELVASGTVSLGKNGKICWAKEE
NT seq
2973 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgaatccttgtaattggctctggaggcagggaacataccctggcctggaaa
ctcggacagtctcaccacgtccaacaggtgttggtggccccaggaaatgcaggcactgcc
tgctcgggaaagatttcaaatactgccatctcaatcagtgaccatacagctcttgctcag
ttctgcaaagatgaaaaaattgagtttgtagttgttggaccagaggcacccctagctgct
ggcattgttggggacctgacctctgcaggagtgcgatgctttggccccaatgcagaagca
gctcagttggagtccagcaaaaggtttgccaaggagtttatggaccgacatggaatccca
actgcacagtggagagctttcaccaaagcagaagaggcctgtggcttcattatgagggct
gacttccctgctctggttgtgaaggccagtggcctggcagctgggaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtgcaggagatcatgcaagagaaagctttt
ggagcagctggagaaacaattgttgttgaagaacttcttgaaggagaagaagtatcttgt
atgtgtttcaccgacgggaggactgtggttcccatgcccccagcacaggaccataagcga
ttactggaaggagaccttggacccaacaccggaggaatgggagcttactgtccagcaccc
caggtttccaaggatttgttactaaaaattaaaaatactgttcttcagaggacagtagat
ggcatgcagcaagagggcacgccatacacaggagttctgtacgctggtataatgctgaca
aaggatggcccaaaagtcctggagtttaactgccgttttggtgatcctgagtgccaagta
atcctcccacttcttaaaagtgatctttacgaaatgattcagtctaccttagatggctcg
ctgggcgcatctccacccatttggctagatgaccacactgcagtgaccgtggtcatggca
agtaaaggttatcctggagcctacaccaaaggcatggagatcacaggctttcctgaggct
caagctttaggactagaggtgttccacgcaggcactgccctcaaagatgggaaagtagta
accagcgggggtagagtccttacagtgacagccgtccgggaaaatctcaaattggctctt
gaggaagcccagaaaggactcgcggttatcaagtttgagggagccgtgtataggaaggac
attggctttcgcgcaatagctttcctccagcagcccaggggcctgacttataagggctct
ggggtagacattgaagctggaaatatgctggttaagaaaattcagcctttagcaaaagct
acctccagacctggatgtgatgttgatcttggaggttttgctggcctctttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctggaacagatggtgttgggactaaactg
aagattgcccagctgtgcaataaacacagtaccattggtcaagatttggttgcaatgtgt
gtaaatgatattctggcacaaggagcagagcccctgttcttccttgattatttttcctgt
ggaaaactggacctcagtacgaccgaagctgtcatcgctggagtcagtgaggcttgtaaa
gaagctgggtgtgctctcctaggaggtgaaacggcagaaatgccggacatgtaccctccc
ggagaatatgacctagcaggttttgctgttggtgctatggagcgagatgagaaactccct
cacctggaacagatcgtggaagaggacaccattgttgggatagcctcatctggtcttcat
agcaatggatttagccttgtaaggaaaattgtggcacagtcttcattggaatactcctct
ccagcacctgctggttgtggtgaccagactttaggagacttacttctcactccaaccaga
atctacagccgttcactgttacctgtcattcgttcaggacatctagacagctcttgcttg
ttcccagatgcccgaacctggaggatccccagagtcttctcatggctacagcaggaaggg
cagctctctgaagaggagatggccagaacatttaactgtggagttggagctgccctcgtg
gtttcaaaaagtcagacagagcaaattctgagagagattcagcagcgccaggaggaggcc
tgggtgattggcagcgtggttgcctgccctaaaggttccccgcgtgtgaaagtcaagaat
ctgattgaagccatgcagatgaatgggtcagtgttggtgaatggctccttgaagactcat
ttccctgcccagcctacaaaggcaagagtggctgtcttgatctctggaacaggatcgaac
ctccaagcacttatagacagcactcaggatccaaacagctctgcagacatcgttgtcgtt
atttccaacaaagctgcagtggctggattaaacaaagctgaaagagctggcattcctacc
agagtaattaatcacaaattatataaaaatcgtgaagaatttgacaatgccattgaccaa
gtccttgaagagttctccacagacatagtctgtctcgcagggttcatgagaattctgtct
ggcccctttgtcagaaaatgggatgggaaaatgcttaatatccacccatccctgctacct
tcctttaagggttcaaatgctcacgagcaagtcctggaagccggagtcacaatcactggg
tgcactgtgcactttgtagctgaagacgttgatgctggacagattattttacaagaggcc
gttcctgtgaagaggggtgacactgttgcaactttgtctgagaaagtaaaagtagcagag
cataaaatatttcctaaagcccttgagcttgtggccagcggaacagtatcgcttggaaaa
aacggcaagatctgttgggccaaagaagaataa
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