KEGG   Cavia porcellus (domestic guinea pig): 100730075
Entry
100730075         CDS       T07777                                 
Symbol
Nfkb1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc01523  Antifolate resistance
cpoc04010  MAPK signaling pathway
cpoc04014  Ras signaling pathway
cpoc04024  cAMP signaling pathway
cpoc04062  Chemokine signaling pathway
cpoc04064  NF-kappa B signaling pathway
cpoc04066  HIF-1 signaling pathway
cpoc04071  Sphingolipid signaling pathway
cpoc04151  PI3K-Akt signaling pathway
cpoc04210  Apoptosis
cpoc04211  Longevity regulating pathway
cpoc04218  Cellular senescence
cpoc04380  Osteoclast differentiation
cpoc04613  Neutrophil extracellular trap formation
cpoc04620  Toll-like receptor signaling pathway
cpoc04621  NOD-like receptor signaling pathway
cpoc04622  RIG-I-like receptor signaling pathway
cpoc04623  Cytosolic DNA-sensing pathway
cpoc04625  C-type lectin receptor signaling pathway
cpoc04657  IL-17 signaling pathway
cpoc04658  Th1 and Th2 cell differentiation
cpoc04659  Th17 cell differentiation
cpoc04660  T cell receptor signaling pathway
cpoc04662  B cell receptor signaling pathway
cpoc04668  TNF signaling pathway
cpoc04722  Neurotrophin signaling pathway
cpoc04917  Prolactin signaling pathway
cpoc04920  Adipocytokine signaling pathway
cpoc04926  Relaxin signaling pathway
cpoc04931  Insulin resistance
cpoc04932  Non-alcoholic fatty liver disease
cpoc04933  AGE-RAGE signaling pathway in diabetic complications
cpoc04936  Alcoholic liver disease
cpoc05010  Alzheimer disease
cpoc05022  Pathways of neurodegeneration - multiple diseases
cpoc05030  Cocaine addiction
cpoc05132  Salmonella infection
cpoc05133  Pertussis
cpoc05134  Legionellosis
cpoc05135  Yersinia infection
cpoc05140  Leishmaniasis
cpoc05142  Chagas disease
cpoc05145  Toxoplasmosis
cpoc05146  Amoebiasis
cpoc05152  Tuberculosis
cpoc05160  Hepatitis C
cpoc05161  Hepatitis B
cpoc05162  Measles
cpoc05163  Human cytomegalovirus infection
cpoc05164  Influenza A
cpoc05165  Human papillomavirus infection
cpoc05166  Human T-cell leukemia virus 1 infection
cpoc05167  Kaposi sarcoma-associated herpesvirus infection
cpoc05168  Herpes simplex virus 1 infection
cpoc05169  Epstein-Barr virus infection
cpoc05170  Human immunodeficiency virus 1 infection
cpoc05171  Coronavirus disease - COVID-19
cpoc05200  Pathways in cancer
cpoc05202  Transcriptional misregulation in cancer
cpoc05203  Viral carcinogenesis
cpoc05206  MicroRNAs in cancer
cpoc05207  Chemical carcinogenesis - receptor activation
cpoc05208  Chemical carcinogenesis - reactive oxygen species
cpoc05212  Pancreatic cancer
cpoc05215  Prostate cancer
cpoc05220  Chronic myeloid leukemia
cpoc05221  Acute myeloid leukemia
cpoc05222  Small cell lung cancer
cpoc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cpoc05321  Inflammatory bowel disease
cpoc05415  Diabetic cardiomyopathy
cpoc05417  Lipid and atherosclerosis
cpoc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100730075 (Nfkb1)
   04064 NF-kappa B signaling pathway
    100730075 (Nfkb1)
   04668 TNF signaling pathway
    100730075 (Nfkb1)
   04066 HIF-1 signaling pathway
    100730075 (Nfkb1)
   04071 Sphingolipid signaling pathway
    100730075 (Nfkb1)
   04024 cAMP signaling pathway
    100730075 (Nfkb1)
   04151 PI3K-Akt signaling pathway
    100730075 (Nfkb1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100730075 (Nfkb1)
   04620 Toll-like receptor signaling pathway
    100730075 (Nfkb1)
   04660 T cell receptor signaling pathway
    100730075 (Nfkb1)
   04658 Th1 and Th2 cell differentiation
    100730075 (Nfkb1)
   04659 Th17 cell differentiation
    100730075 (Nfkb1)
   04657 IL-17 signaling pathway
    100730075 (Nfkb1)
   04662 B cell receptor signaling pathway
    100730075 (Nfkb1)
   04062 Chemokine signaling pathway
    100730075 (Nfkb1)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    100730075 (Nfkb1)
   04926 Relaxin signaling pathway
    100730075 (Nfkb1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100730075 (Nfkb1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100730075 (Nfkb1)
  09149 Aging
   04211 Longevity regulating pathway
    100730075 (Nfkb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100730075 (Nfkb1)
   05202 Transcriptional misregulation in cancer
    100730075 (Nfkb1)
   05206 MicroRNAs in cancer
    100730075 (Nfkb1)
   05207 Chemical carcinogenesis - receptor activation
    100730075 (Nfkb1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100730075 (Nfkb1)
   05203 Viral carcinogenesis
    100730075 (Nfkb1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100730075 (Nfkb1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100730075 (Nfkb1)
   05221 Acute myeloid leukemia
    100730075 (Nfkb1)
   05220 Chronic myeloid leukemia
    100730075 (Nfkb1)
   05215 Prostate cancer
    100730075 (Nfkb1)
   05222 Small cell lung cancer
    100730075 (Nfkb1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100730075 (Nfkb1)
   05170 Human immunodeficiency virus 1 infection
    100730075 (Nfkb1)
   05161 Hepatitis B
    100730075 (Nfkb1)
   05160 Hepatitis C
    100730075 (Nfkb1)
   05171 Coronavirus disease - COVID-19
    100730075 (Nfkb1)
   05164 Influenza A
    100730075 (Nfkb1)
   05162 Measles
    100730075 (Nfkb1)
   05163 Human cytomegalovirus infection
    100730075 (Nfkb1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100730075 (Nfkb1)
   05169 Epstein-Barr virus infection
    100730075 (Nfkb1)
   05165 Human papillomavirus infection
    100730075 (Nfkb1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100730075 (Nfkb1)
   05133 Pertussis
    100730075 (Nfkb1)
   05134 Legionellosis
    100730075 (Nfkb1)
   05152 Tuberculosis
    100730075 (Nfkb1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100730075 (Nfkb1)
   05145 Toxoplasmosis
    100730075 (Nfkb1)
   05140 Leishmaniasis
    100730075 (Nfkb1)
   05142 Chagas disease
    100730075 (Nfkb1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100730075 (Nfkb1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100730075 (Nfkb1)
   05022 Pathways of neurodegeneration - multiple diseases
    100730075 (Nfkb1)
  09165 Substance dependence
   05030 Cocaine addiction
    100730075 (Nfkb1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100730075 (Nfkb1)
   05418 Fluid shear stress and atherosclerosis
    100730075 (Nfkb1)
   05415 Diabetic cardiomyopathy
    100730075 (Nfkb1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100730075 (Nfkb1)
   04932 Non-alcoholic fatty liver disease
    100730075 (Nfkb1)
   04931 Insulin resistance
    100730075 (Nfkb1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100730075 (Nfkb1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100730075 (Nfkb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:cpoc03000]
    100730075 (Nfkb1)
Transcription factors [BR:cpoc03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    100730075 (Nfkb1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 100730075
NCBI-ProteinID: XP_003468075
Ensembl: ENSCPOG00000007789
UniProt: H0VAV7
LinkDB
Position
Unknown
AA seq 967 aa
MTDDDSYLRGHEQMFHLPPLTHAIFNPELFPPEMPLPTADGPYLQILEQPKQRGFRFRYV
CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNVHLHAHSLVGKHCED
GVCTVTAGPKDMVVSFANLGILHVTKKKVFETLEARMTDACVRGYNPGLLVHPDLAYLQA
EGGGGDRQLTDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI
YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGD
FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV
QRKRQKLMPNFSDSFGGGGGGTGAGGGGMFGGGGSGAGGTGGTGPGYGFPHYGFPTYSGI
AFHPGTTKSNAGMKHGTVNTERNQDPEGCDAGENETVLPATEAEEEPAEPSPGEDGVPLT
HAPAEEDKDMGLQDNLFLEKALQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGD
SVLHLAVIHLHAQLVRDLLQVTSGLISEDIINMRNDLYQTPLHLAVITKQEDVVEDLLQA
GADLSLLDRLGNSALHLAAKEGQDKILSVLLKHRKAALLMDQPNGEGLNAIHIAVTSNSL
SCLLLLVAAGADVNAQEQKSGRTALHLAVEQDNVSLAGCLLLEGEAHVDSTTYDGTTPLH
IAAGRGSTRLAALLKAAGADPLVENFEPLYDWDESWERTGEDEGVVPGTTPLDMAASWQV
FDILNGKPYEPEVVADDPLAQGDMKQLSEEAKLQLYKLLEIPDPDRNWATLAQKLGLGIL
NHAFRLSPAPAKTLMDNYEVSGGTVKELLEALAQMGYTEAIEVIQAACCGSGTPSSMKGT
TQAPLLSLSISPQIDELRDQDSICDSGVETSFRKLSFTESLTGGGPLLTLNKGSPEFGQQ
GPIEGKI
NT seq 2904 nt   +upstreamnt  +downstreamnt
atgacggacgacgattcgtatctgagagggcacgaacaaatgtttcacctgcctcctctg
acgcatgccatatttaacccagaattatttccaccagagatgcccctgccgacagcagat
ggtccataccttcaaatattagagcaacctaaacagagaggattccgtttccgttacgtg
tgtgaaggcccctcccacggtgggcttccgggcgcatccagtgagaagaacaagaagtcc
tacccgcaggtcaaaatctgcaactacgtgggccctgccaaagtcattgtccagctggtc
acaaacgggaagaatgtccacctccacgcccacagcctggtgggaaaacactgcgaggac
ggcgtctgcactgtcaccgcgggccccaaggacatggtagtcagcttcgccaacctgggc
atcctccacgtgacaaagaagaaggtgttcgagaccctggaggctcggatgacagacgcg
tgcgtcaggggctacaaccctgggctcctggtgcaccccgatctcgcctacctgcaggcc
gagggtggcggaggcgaccggcagctcacggaccgagaaaaggagctcatccgccaggcg
gccctgcagcagaccaaggagatggacctgagcgtggtgcggctcatgttcaccgccttc
ctgcccgacagcaccggcagcttcacgcggcgcctggagcctgtggtgtctgacgccatc
tacgacagcaaggctcccaatgcatccaacttgaaaatcgtaagaatggacagaacggct
ggatgtgtaactggcggggaggagatttacctcctctgtgacaaagtacagaaagatgac
attcagattcggttctatgaagaggaggagaacggaggcatctgggaagggtttggagac
ttctccccgacggacgtccacagacaatttgctattgtcttcaaaactccgaagtataaa
gacatcaacatcaccaaaccggcatctgtgtttgtccagcttcggaggaagtcagacttg
gaaacgagcgagcccaagcctttcctctactaccccgaaatcaaagacaaagaggaagta
cagaggaagcggcagaagctgatgcccaacttctcagacagcttcggcggcggtggtggc
ggcacgggcgcaggaggcgggggcatgtttggtggtggtggcagcggagcagggggcaca
ggcggcaccggaccagggtatggcttcccacactacggattcccgacatacagtgggatc
gccttccatcctggaaccaccaagtccaacgccggcatgaaacatggaactgtaaacact
gaacggaatcaggaccctgaaggctgtgatgctggtgaaaatgagacagtgctcccagcc
acagaagcagaggaggagcctgccgagcccagccccggggaggacggggtgccgctgacc
cacgccccggcagaagaggacaaggacatggggcttcaggacaacctgttcttggagaag
gccctgcagctcgccaagcgccatgccaacgccctcttcgactacgcagtcacaggggac
gtgaagatgctgctggctgtgcagcgccatctcaccgcggtgcaggatgagaatggcgac
agcgtcttgcaccttgctgtcatccacctccacgcccagctcgtgagggacctcttgcaa
gtaacctcaggactgatttccgaggacatcatcaacatgagaaatgatctctaccagaca
cccttgcacttagcagtgatcacgaagcaggaggacgtggtagaggacctgctgcaggct
ggagcggacctgagcctgctggaccgcctgggcaactctgcactgcaccttgctgccaag
gaggggcaggacaaaatcctcagcgtcctgctcaagcaccggaaggcggcgctgctgatg
gaccagcccaatggcgaaggtctcaatgccatccacattgccgtgacaagcaacagcctt
tcctgcctgctgttgctggtggccgcaggtgccgacgtcaatgcccaggaacagaagtcg
gggcgcacggcactacacctggcagtggagcaggacaatgtgtccctggcgggctgtctg
ctgctcgagggtgaagcccatgtggacagcaccacctatgatgggaccacaccactgcat
attgcagccgggcgaggctccaccaggttggctgcactgctcaaggctgcaggggcagac
cccttagtggagaacttcgagcccctgtacgactgggatgagtcctgggaaaggaccggc
gaggacgaaggtgtggtgccagggacgacgccactggacatggcggccagctggcaggtg
tttgacatcctaaacgggaagccatacgagcccgaggtcgtggccgatgaccccctggct
caaggggacatgaagcagctgagcgaggaagccaagctgcagctctacaagctgctagaa
atccccgacccggacagaaactgggcgacgctggcacagaagctgggcctgggcatcctg
aaccacgccttccggctgagccctgcaccagccaagaccctgatggacaactacgaggtc
tcgggaggcaccgtcaaggagctgctggaggccttagcacagatgggctacacggaagcc
atcgaagtgatccaggcagcctgctgcggctcagggacccccagctccatgaagggtacc
acgcaggcccccctgctgtccctgtcaatatcaccgcagatcgatgagcttcgagaccag
gacagcatctgtgacagcggcgtggagacctccttccgcaagctcagcttcacggagtct
ctgacgggcggtggccccttgctaacacttaacaaaggttcgcccgaatttgggcagcaa
ggacccatagaaggcaagatctag

DBGET integrated database retrieval system