Cavia porcellus (domestic guinea pig): 100730168
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Entry
100730168 CDS
T07777
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100730168 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
cpoc03032
]
100730168 (Top2a)
03036 Chromosome and associated proteins [BR:
cpoc03036
]
100730168 (Top2a)
Enzymes [BR:
cpoc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100730168 (Top2a)
DNA replication proteins [BR:
cpoc03032
]
Eukaryotic type
DNA Topoisomerases
100730168 (Top2a)
Chromosome and associated proteins [BR:
cpoc03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100730168 (Top2a)
Centrosome formation proteins
Centriole proteins
100730168 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
100730168
NCBI-ProteinID:
XP_013005083
Ensembl:
ENSCPOG00000006799
LinkDB
All DBs
Position
Unknown
AA seq
1541 aa
AA seq
DB search
MEVSPLQPVNEHMQMNKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELLTQQ
MWVYDEDIGINYREITFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISVWN
NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDERKVTGGRNGYGAKLCNIFSTRFTVE
TASKDYKKMFKQTWMDNMGRAGEMELKPFSGEDYTCITFQPDLSKFKMERLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVTGFRSYVDMYLKDKLDETGNPLKVIHEQVNQRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLMDVVKKKNKGGIAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNKIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYADEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLQHRFLEEFITPIVKVSKNKQELAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKKHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
VNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLNFLYDDNQRVEPEW
YIPIIPMVLVNGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELASNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFIVKMTEEKLSEVERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPEEEENEESDSEKEAAKGDPAADSGPTFNYLLDMPLWYLTKEK
KDELCRQRDEKEQELDTLKKKSPSDLWREDLAAFIEELEVVEAKEKQDEQVGLVGKGGKG
KGKKAPAAETLPSLQGIRVVPRVTTEMKAEAEKKIRKKLKTENTEGAPAEDSVEMDSLKL
KLEKKQKTEPGTKAKKQTTLPFKPVKKGKKRNPWSDSDSEMSSTSEGHFDLPSREVKQRR
AAANTRFTMDLDSDEDFSDFDKKNDDDFVPSDASPLKAKSLPQLTKKEPKPQKSIASVAG
PEPEDSEDGGLPASGPSDDAPARLPASSVTTKKTATKAGQSSSPTTGAKKRAVPKRAPTA
GDKKRAVPKRAKKDPALDPEAPEKPDPKTKSRCKRRPSSSSDDSDSSLAKMAPKGARNKR
PKAEGDDFQLDLQSAVAPRAKSARARKPIKYLEESDEDELF
NT seq
4626 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtcaatgaacatatgcaaatgaacaaaattaagaaa
aatgaagatgccaagaaaagactgtctatcgaaagaatctatcaaaagaaaacgcagttg
gaacatatattgctccgcccagacacttacattgggtctgtggaattactgacccagcaa
atgtgggtttatgatgaagatattggcattaactacagagaaatcactttcgttcctggt
ttgtacaaaatctttgatgagattctagttaatgctgcggacaacaaacagagagatcca
aaaatgtcttgtattagagtcacaattgacccagaaaacaacttaattagtgtatggaat
aatggaaaaggaattcctgttgtggagcacaaagtcgagaaggtgtatgtccccgctctc
atatttggtcagctcttaacatctagtaactatgacgatgatgaaaggaaggtaacaggt
ggacgaaatggctatggagccaaactgtgtaacatattcagtaccagattcactgtcgaa
acagccagtaaagattacaagaaaatgttcaaacagacatggatggataacatggggaga
gctggtgagatggagctcaagccctttagtggggaagattatacctgcatcaccttccag
cctgatttgtctaagtttaaaatggaacgcctggacaaagatattgttgccctgatggtg
aggagagcatatgatattgccggctccactaaagatgtcaaagtctttctcaatggaaat
aagttgccggtaacaggattccgtagctacgtggatatgtatttaaaggataagttagat
gaaactggcaacccactgaaagtgatacatgaacaagtaaaccagcgatgggaggtgtgc
ctcaccatgagtgagaagggcttccagcagatcagcttcgtcaatagcattgctacctcc
aagggtggcagacatgttgactacgtagctgatcagattgtgaccaaactcatggatgta
gtgaagaagaagaacaagggtggcattgccgtgaaagcacatcaggtgaagaatcacatg
tggatttttgtgaatgccttaattgaaaacccaaccttcgactctcagacaaaagaaaac
atgactttacaagtcaagagctttggatccacatgccaattaagtgaaaaattcatcaaa
gctgcaattggctgtggcattgtggaaagcatactgaattgggtgaagtttaaggcccag
gtccagttaaacaagaagtgttcagcagtcaagcataacaaaatcaagggaatccccaag
ctggacgatgccaatgatgcaggaagccgaaattccacagagtgcacgcttattctgact
gagggggactcagccaaaactttggctgtttcaggccttggcgtggttggacgagacaaa
tacggggttttccctcttagaggaaaaatgctcaatgtccgggaagcgtctcataagcag
atcatggaaaatgctgaaattaataacatcatcaagattgtgggtcttcaatataagaaa
aactatgcagatgaagattcactgaagactcttcgttatggaaaaataatgattatgact
gatcaggatcaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcaacatcgttttctggaggaatttatcactcccattgtgaaggtg
tctaaaaataagcaagaactggccttctacagccttcctgaatttgaagaatggaagagt
tctactccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagccaaggaatactttgcagatatgaaaaaacatcgaatccaattcaaatat
tctgggcccgaagatgatgctgccattagcttggcctttagcaaaaagcagatagatgat
cgaaaggagtggttaactcatttcatggaagacagaagacaacggaagttacttggtctt
cctgaggattatttgtacgggcaaactaccacttacctgacatataatgacttcatcaac
aaggaacttatcctgttctcaaattctgataacgagagatctatcccatctatggtggat
ggtttgaaaccagggcagagaaaggttttgtttacttgtttcaagcggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtggcagaaatgtcctcttaccatcatggc
gagatgtcactaatgatgacaatcatcaatttggctcagaattttgtgggcagcaataat
gtgaacctcttgcaacccattggtcagtttggcaccaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttgtttccaccg
aaagatgaccacaccctgaacttcttgtacgatgacaaccagcgtgtggagccagagtgg
tacatccccatcattcccatggtgctggtgaacggggccgaggggatcggcaccggctgg
tcctgcaagatccccaacttcgatgtgcgggaaattgtaaataacatcaggcgtttaatg
gatggagaagaacctctgccgatgcttccaagttataagaacttcaagggtactattgaa
gaactggcttcaaatcagtatgtgattaatggtgaagtagccattctgaattctacaacc
attgaaatctcagagcttcccatcagaacatggacccagacatacaaagagcaagtccta
gaacccatgttgaatggcaccgagaagaccccacctctcataacagactacagggagtac
cacacagacactaccgtcaagttcattgtgaagatgactgaagaaaagctgtcagaggtg
gagagagccgggctccataaagtcttcaaactccagaccagcctcacctgcaactccatg
gtgctctttgaccacgtaggctgtttaaagaaatacgacacagtgctggacatactgaga
gacttctttgaactcaggcttaaatactatggattaaggaaagagtggctcctaggaatg
cttggcgctgaatcctctaaattgaacaatcaagctcgctttatactggagaagatagat
ggcaaaataatcattgaaaacaagcccaagaaagagctgattaaggttctgattcagagg
ggctatgactccgaccctgtgaaggcctggaaagaagcccagcagaaggttccagaggaa
gaagaaaatgaagaaagcgacagcgaaaaggaggccgcaaagggtgaccctgcagctgac
agcgggccaaccttcaactacctcctggacatgcccctctggtacctgaccaaggaaaag
aaggacgagctgtgccgacagagggatgaaaaggagcaagagctggacacactaaagaaa
aagagtccatccgacttgtggagggaagacctggctgctttcattgaagagctggaggtt
gttgaagccaaagaaaaacaagatgagcaagtgggacttgtgggaaaaggaggaaaaggg
aaagggaaaaaggcacccgcagctgaaaccctgccttctctgcaaggaatcagagtcgtc
ccccgagtgaccacagagatgaaagcagaggcagaaaagaaaatcaggaaaaaacttaag
actgaaaatactgaaggggcccctgctgaagacagtgtggaaatggatagcctgaaacta
aagttagaaaagaaacagaagacagaaccaggtaccaaggcaaagaaacaaaccacattg
ccatttaagcctgtcaaaaaaggaaagaagagaaacccctggtctgactctgactcagaa
atgagtagcacttctgaaggtcattttgacctcccgtcacgggaggtgaagcagcggcga
gctgcagcaaacaccagattcaccatggatttggactcagatgaagatttctcagatttt
gataaaaaaaatgatgatgactttgttccatcagatgctagtcctctgaaggccaagagc
ctcccacaacttactaaaaaagaaccaaagccacagaaaagcattgcgtcagtcgctggc
cctgagcctgaggactcagaggatggggggctccctgcctctggcccttccgacgatgcc
cctgccaggctgcctgcaagcagcgtgaccaccaagaagacagcaaccaaagcaggtcag
tcttccagccctaccactggggccaagaagagggcggtgcccaagagggcccctaccgct
ggggacaagaagagggcggtgcccaagagggccaaaaaggacccagccttggaccctgaa
gcccctgaaaaacctgatcccaaaaccaagagccgctgcaaaaggaggccctcttcctcc
tcggatgactccgactccagcttagcaaagatggctcccaaaggggccaggaacaagaga
cccaaggcagaaggtgacgacttccagctggacctccagtcggccgtggccccgcgggcg
aagtctgcccgtgccaggaagcccataaagtacctggaggagtccgatgaggacgagctg
ttttaa
DBGET
integrated database retrieval system
