Entry
Symbol
Mgst2
Name
(RefSeq) microsomal glutathione S-transferase 2
KO
Organism
cpoc Cavia porcellus (domestic guinea pig)
Pathway
cpoc00980 Metabolism of xenobiotics by cytochrome P450
cpoc05204 Chemical carcinogenesis - DNA adducts
cpoc05207 Chemical carcinogenesis - receptor activation
cpoc05208 Chemical carcinogenesis - reactive oxygen species
cpoc05418 Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cpoc00001 ]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100730296 (Mgst2)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
100730296 (Mgst2)
00982 Drug metabolism - cytochrome P450
100730296 (Mgst2)
00983 Drug metabolism - other enzymes
100730296 (Mgst2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100730296 (Mgst2)
05204 Chemical carcinogenesis - DNA adducts
100730296 (Mgst2)
05207 Chemical carcinogenesis - receptor activation
100730296 (Mgst2)
05208 Chemical carcinogenesis - reactive oxygen species
100730296 (Mgst2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100730296 (Mgst2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100730296 (Mgst2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100730296 (Mgst2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:cpoc02000 ]
100730296 (Mgst2)
Enzymes [BR:cpoc01000 ]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.18 glutathione transferase
100730296 (Mgst2)
Transporters [BR:cpoc02000 ]
Other transporters
Pores ion channels [TC:1 ]
100730296 (Mgst2)
BRITE hierarchy
SSDB
Ortholog Paralog GFIT
Motif
Motif
Other DBs
LinkDB
All DBs
Position
Unknown
AA seq
147 aa AA seq DB search
MAGDAVLLAAVSLLSACQQSYFAFRVGRTRLKCKVMPPAVTGSLEFERVFRAQQNCVEFY
PVFLIALWMAGWYFNQVFASCLGLAYIYSRHKYFWGYSEAAEKRMGGFLSSLGILALLTV
LGALGIANVFLDEYLDVHVGKKLGRYF
NT seq
444 nt NT seq +upstream nt +downstream nt
atggcgggggatgcagtgctgctggcggctgtctctctcctctctgcttgtcagcaaagt
tattttgctttccgggttggaaggacaagattaaaatgcaaggtgatgcccccggctgtc
actgggtctctggagtttgagagagtgtttcgtgcacaacaaaactgtgtggaattttac
cctgtgttcttgattgcactgtggatggctggatggtatttcaaccaagtttttgcttct
tgtctgggtctagcgtacatatatagccgtcacaagtacttctggggatattcagaagct
gctgaaaaaaggatgggcggtttcctgtcgagcctggggattttggccttgttgacggtc
ctgggtgccctgggcatcgcaaacgtctttctcgatgaatatctggacgtccatgttggc
aagaaactggggcggtacttctaa