Cavia porcellus (domestic guinea pig): 100731108 Help Entry 100731108         CDS       T07777                                  Symbol Hspa5 Name (RefSeq) 78 kDa glucose-regulated protein   KO K09490   endoplasmic reticulum chaperone BiP [EC:5.6.1.10] Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc03060   Protein export cpoc04141   Protein processing in endoplasmic reticulum cpoc04612   Antigen processing and presentation cpoc04918   Thyroid hormone synthesis cpoc05012   Parkinson disease cpoc05014   Amyotrophic lateral sclerosis cpoc05020   Prion disease cpoc05022   Pathways of neurodegeneration - multiple diseases cpoc05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:cpoc00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    03060 Protein export     100731108 (Hspa5)    04141 Protein processing in endoplasmic reticulum     100731108 (Hspa5)  09150 Organismal Systems   09151 Immune system    04612 Antigen processing and presentation     100731108 (Hspa5)   09152 Endocrine system    04918 Thyroid hormone synthesis     100731108 (Hspa5)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     100731108 (Hspa5)    05014 Amyotrophic lateral sclerosis     100731108 (Hspa5)    05020 Prion disease     100731108 (Hspa5)    05022 Pathways of neurodegeneration - multiple diseases     100731108 (Hspa5)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100731108 (Hspa5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03110 Chaperones and folding catalysts [BR:cpoc03110]     100731108 (Hspa5)    04131 Membrane trafficking [BR:cpoc04131]     100731108 (Hspa5)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:cpoc04147]     100731108 (Hspa5) Enzymes [BR:cpoc01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.1  Enzymes altering polypeptide conformation or assembly     5.6.1.10  non-chaperonin molecular chaperone ATPase      100731108 (Hspa5) Chaperones and folding catalysts [BR:cpoc03110]  Heat shock proteins   HSP70 / DNAK    100731108 (Hspa5) Membrane trafficking [BR:cpoc04131]  Endoplasmic reticulum (ER) - Golgi transport   Forward pathways    ER-Golgi intermediate compartment (ERGIC) proteins     100731108 (Hspa5)  Autophagy   ER-phagy    ER stress-related proteins     100731108 (Hspa5) Exosome [BR:cpoc04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    100731108 (Hspa5)   Exosomal proteins of other body fluids (saliva and urine)    100731108 (Hspa5)   Exosomal proteins of colorectal cancer cells    100731108 (Hspa5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  HSP70 MreB_Mbl FtsA Hydantoinase_A FGGY_C DDR ParM_N NPA Motif Other DBs NCBI-GeneID:  100731108 NCBI-ProteinID:  XP_003470822 Ensembl:  ENSCPOG00000012520 LinkDB All DBs Position Unknown AA seq 654 aa AA seqDB search MKLCLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVED KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL NT seq 1965 nt NT seq  +upstreamnt  +downstreamnt atgaagctgtgtctggtggctgcggtccttctgctgctcggcgcggcgcgggccgaggag gaggacaagaaggaggacgtaggcacggtggtcggcatcgacctggggaccacctactcc tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgc atcacgccatcgtatgtggccttcacccccgaaggggagcggctgatcggcgatgcggcc aagaaccaactcacctccaaccccgagaacactgttttcgacgccaagcggctcatcgga cgcacttggaacgacccctccgttcagcaagacatcaagttcttgcctttcaaggtggtt gaaaagaaaactaaaccatacattcaggttgatattggaggtgggcaaaccaagactttt gctccagaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggcttat ttgggaaagaaggttactcatgcagtcgttactgtacctgcctactttaatgatgctcaa aggcaagcaaccaaagatgctggaacaattgctggactgaatgttatgagaatcatcaat gagccgacagcagctgccattgcttatggcctggataagagagagggggagaagaacatc ctggtgtttgacctgggtggtggaaccttcgatgtatctcttctcaccatcgacaatggt gtcttcgaagtcgtggccactaatggagatactcacctgggtggagaggactttgaccag cgtgtcatggaacacttcatcaagctgtacaaaaagaagactggcaaagatgtgaggaag gacaacagagctgtgcagaaactccgacgtgaggtagaaaaggccaagagggccctatct tctcagcatcaggcaagaattgaaattgaatctttctatgaaggagaagacttttctgag actctgactcgggccaaatttgaagaactaaacatggacctgttccgctctaccatgaaa cctgtccagaaagtgttggaagactctgacttgaagaagtctgatattgatgagattgtt cttgttggtggctccactcgaattcccaagatccagcaactggttaaagagttcttcaat ggcaaggagccatcccgaggcataaacccagatgaggctgtagcctatggtgctgctgtc caggcaggtgtactctctggtgaccaagatacaggagacctggtactgcttgatgtatgt ccccttacacttggcattgaaactgtgggaggtgtcatgaccaaactgattccaagaaac actgtagtccctaccaagaagtctcagatcttttccacagcttctgataatcaaccaact gttacaatcaaagtctatgaaggtgagcgacctctgacgaaagacaatcacctcctgggt acatttgacctgactggaattcctcctgctccccgtggggtcccccagattgaagtcacc tttgagatagatgtgaatggcattcttcgggtgacagctgaagacaagggtacagggaac aaaaataagatcacaatcaccaatgaccaaaatcgcctaacacctgaagagatcgaaagg atggtcaatgatgctgagaagtttgctgaggaagacaaaaagctcaaggagcgcatagac acccggaatgagctggaaagctacgcctactctctaaagaaccagattggagataaagaa aagctgggaggcaaactttcctcggaagacaaggaaaccatggaaaaagctgtagaggac aagattgaatggctggaaagccaccaagatgctgacattgaagacttcaaagcaaagaag aaggaattagaagaaatcgttcagccaatcatcagcaaactctatggaagtgcaggccct cctccgactggtgaagaggatacagcagaaaaagacgagttgtag

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