KEGG   Cavia porcellus (domestic guinea pig): 100732296
Entry
100732296         CDS       T07777                                 
Symbol
Atf4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc04010  MAPK signaling pathway
cpoc04022  cGMP-PKG signaling pathway
cpoc04137  Mitophagy - animal
cpoc04141  Protein processing in endoplasmic reticulum
cpoc04151  PI3K-Akt signaling pathway
cpoc04210  Apoptosis
cpoc04211  Longevity regulating pathway
cpoc04261  Adrenergic signaling in cardiomyocytes
cpoc04668  TNF signaling pathway
cpoc04720  Long-term potentiation
cpoc04722  Neurotrophin signaling pathway
cpoc04725  Cholinergic synapse
cpoc04728  Dopaminergic synapse
cpoc04911  Insulin secretion
cpoc04912  GnRH signaling pathway
cpoc04915  Estrogen signaling pathway
cpoc04918  Thyroid hormone synthesis
cpoc04922  Glucagon signaling pathway
cpoc04925  Aldosterone synthesis and secretion
cpoc04926  Relaxin signaling pathway
cpoc04927  Cortisol synthesis and secretion
cpoc04928  Parathyroid hormone synthesis, secretion and action
cpoc04932  Non-alcoholic fatty liver disease
cpoc04934  Cushing syndrome
cpoc04935  Growth hormone synthesis, secretion and action
cpoc05010  Alzheimer disease
cpoc05012  Parkinson disease
cpoc05014  Amyotrophic lateral sclerosis
cpoc05020  Prion disease
cpoc05022  Pathways of neurodegeneration - multiple diseases
cpoc05030  Cocaine addiction
cpoc05031  Amphetamine addiction
cpoc05034  Alcoholism
cpoc05161  Hepatitis B
cpoc05163  Human cytomegalovirus infection
cpoc05166  Human T-cell leukemia virus 1 infection
cpoc05203  Viral carcinogenesis
cpoc05207  Chemical carcinogenesis - receptor activation
cpoc05215  Prostate cancer
cpoc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100732296 (Atf4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100732296 (Atf4)
   04668 TNF signaling pathway
    100732296 (Atf4)
   04022 cGMP-PKG signaling pathway
    100732296 (Atf4)
   04151 PI3K-Akt signaling pathway
    100732296 (Atf4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    100732296 (Atf4)
  09143 Cell growth and death
   04210 Apoptosis
    100732296 (Atf4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100732296 (Atf4)
   04922 Glucagon signaling pathway
    100732296 (Atf4)
   04912 GnRH signaling pathway
    100732296 (Atf4)
   04915 Estrogen signaling pathway
    100732296 (Atf4)
   04926 Relaxin signaling pathway
    100732296 (Atf4)
   04935 Growth hormone synthesis, secretion and action
    100732296 (Atf4)
   04918 Thyroid hormone synthesis
    100732296 (Atf4)
   04928 Parathyroid hormone synthesis, secretion and action
    100732296 (Atf4)
   04925 Aldosterone synthesis and secretion
    100732296 (Atf4)
   04927 Cortisol synthesis and secretion
    100732296 (Atf4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100732296 (Atf4)
  09156 Nervous system
   04725 Cholinergic synapse
    100732296 (Atf4)
   04728 Dopaminergic synapse
    100732296 (Atf4)
   04720 Long-term potentiation
    100732296 (Atf4)
   04722 Neurotrophin signaling pathway
    100732296 (Atf4)
  09149 Aging
   04211 Longevity regulating pathway
    100732296 (Atf4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100732296 (Atf4)
   05203 Viral carcinogenesis
    100732296 (Atf4)
  09162 Cancer: specific types
   05215 Prostate cancer
    100732296 (Atf4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100732296 (Atf4)
   05161 Hepatitis B
    100732296 (Atf4)
   05163 Human cytomegalovirus infection
    100732296 (Atf4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100732296 (Atf4)
   05012 Parkinson disease
    100732296 (Atf4)
   05014 Amyotrophic lateral sclerosis
    100732296 (Atf4)
   05020 Prion disease
    100732296 (Atf4)
   05022 Pathways of neurodegeneration - multiple diseases
    100732296 (Atf4)
  09165 Substance dependence
   05030 Cocaine addiction
    100732296 (Atf4)
   05031 Amphetamine addiction
    100732296 (Atf4)
   05034 Alcoholism
    100732296 (Atf4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100732296 (Atf4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100732296 (Atf4)
   04934 Cushing syndrome
    100732296 (Atf4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:cpoc03000]
    100732296 (Atf4)
Transcription factors [BR:cpoc03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    100732296 (Atf4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF3450 DUF4407 OVT1 KIF21A Fez1 Asd-4 AAA_13 Nop53 COG3_N GAS
Other DBs
NCBI-GeneID: 100732296
NCBI-ProteinID: XP_003470556
Ensembl: ENSCPOG00000022485
UniProt: H0VUY0
LinkDB
Position
Unknown
AA seq 354 aa
MAEMSFLSSEVLGGDFMSPFDQSALGAEESLGLLDDYLEVAKHFKPHGFSSDRAKAGSSD
YLAVDELVSASDTGKEDAFYGTDWMLEKMDLKEFDFDALLNVDDLETMPDELLATLDDTC
DLFAPLVQETNTEPPQAVNPIGHLPESLTKTDQVAPFTFLQPLPLSPGVLCSTPDHSFSL
EVGSEVDISEGDRKSDTIAYITLVPQCVKEEDAPSDNDSGICMSPESYSGSPQHSPSTSR
GSPFRSLPSPSVPCGSAWPKPYDPPGEKLVAAKVKGEKLDKKLKKMEQNKTAATRYRQKK
RAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKKGPLG
NT seq 1065 nt   +upstreamnt  +downstreamnt
atggccgagatgagcttcctgagcagcgaggtgttggggggggacttcatgtcccccttc
gaccagtcggctttgggggctgaagaaagcttaggtctcttagatgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacagggctaaggcgggctcctccgat
tatctggctgtggatgagttggtcagtgcctcggacaccggcaaggaggatgccttctat
gggacagactggatgttggagaaaatggatctgaaggagtttgattttgatgcgctgttg
aacgtagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacatgt
gatctgtttgcccccctagtccaggagactaatacggagcccccccaggcagtgaaccca
attggccatcttccagaaagtttaacaaaaactgaccaggttgcccctttcaccttcttg
caacctcttcccctttccccaggggttctgtgctctactccagatcattcctttagctta
gaggtaggcagcgaggtggatatttctgaaggagataggaaatctgacaccattgcttac
attaccttggttcctcagtgtgtaaaagaggaagatgccccctcagataatgacagtggc
atctgtatgagtcccgagtcctactctggttctccccagcacagcccctctacctccagg
ggctctccatttaggagcctgccatctccaagtgtcccctgtggttctgcctggcccaaa
ccctatgatccccctggagagaagttggtagcagccaaggttaagggtgaaaagctagat
aagaaactgaaaaaaatggaacaaaacaagacagcagctaccaggtaccgccagaagaaa
cgggcagagcaagaggcgctcactggcgagtgtaaagagctagaaaagaaaaatgaggct
ctgaaagagaaggcagattctctggctaaggagattcagtatctgaaagatctgatagaa
gaggtccgcaaggcaagggggaagaagaagggtcccttagggtag

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