Cavia porcellus (domestic guinea pig): 100732613 Help Entry 100732613         CDS       T07777                                  Symbol Pkd1 Name (RefSeq) polycystin-1 isoform X1   KO K04985   polycystin 1 Organism cpoc  Cavia porcellus (domestic guinea pig) Brite KEGG Orthology (KO) [BR:cpoc00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:cpoc03037]     100732613 (Pkd1)    04812 Cytoskeleton proteins [BR:cpoc04812]     100732613 (Pkd1)    04040 Ion channels [BR:cpoc04040]     100732613 (Pkd1)    04091 Lectins [BR:cpoc04091]     100732613 (Pkd1) Cilium and associated proteins [BR:cpoc03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    100732613 (Pkd1) Cytoskeleton proteins [BR:cpoc04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     100732613 (Pkd1) Ion channels [BR:cpoc04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    100732613 (Pkd1) Lectins [BR:cpoc04091]  C-Type lectins   Others    100732613 (Pkd1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PKD REJ PKD_4 Polycystin_dom PKD_channel PLAT Lectin_C LRR_8 WSC LRRNT LRR_4 GPS Motif Other DBs NCBI-GeneID:  100732613 NCBI-ProteinID:  XP_003478161 Ensembl:  ENSCPOG00000003228 LinkDB All DBs Position Unknown AA seq 4300 aa AA seqDB search MPPGAPARLALALGLGLWLGGLAGAPGRGCGPCAPPCLCGPAPGASCRVNCSGRGLRKLG PELRIPADTTVLDVSHNLLQTLDVGLLANLSALVELDISNNRISTLEEGIFANLFNLSEI NLSRNPFECDCGLVWLRHWAEEKQVLVVQPEEATCTGPGPLAGQPLLGLSLVDTGCGEEY VACLPDNSSDTMVLVAFSIAHEGPLAPEACSTFCFLGGQGLAALSEQGQCLCGTAQTPNI SVACLSLCSNPLPPTPACGGPTFLQHVFPSSPGTTLVGPHGPLASGQPAAFHISTTSLPL STICWDFGDGSPKLDMAGPAATHRYVLPGHYHVTAVLTLGASSITLETEVQVEVAPAALE LVCPSSVHRDESLELSIRNRGGSDLEATYSILALGEEPVQVVHPLCPSDTEIFPGNGHCY RLVAEKAPWLQAQEQCQAWAGAALAMVDSPAIQHFLVSQVTRSLDVWIGFSTVEGAEAGL APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVWD AENFLMGVPGGGLQGPLILLTPQEALLPPRWPVEVMVFPGLSPSREAFLTTAEFETQELG GPAQLRLQVYRPSGRAGAPENRSEPDNRTEPVPRCMPEGCWCPGASLCMPLDAACHLQAC ANESVVEPGLPRATYALWREFLFSVPAGPPTQYLVTFHGQDVPVLPGDLIGLQHDAGSGA LLQCPLTPNQAGSKVLYLSTNASNWLAHLPTLLDDARPGPACILQLVTATERLSPLLGLR SNPGLQHPGRYEVRATVGNNVSTYNLSCSFNVVSPVAGLRVIYPATLDGQLYVPTSGSVL VLQVDSGANATATAYWPGGNVSAPLETACPTMLDALKPICTQETNNTLFSVLVLPGLSQG EHAVDVVVQNSAGRANLTLRVMAEEPIRGLHATPVPEARVLQGALVRYSPMVEAGSNVVF RWTIDDKQSLTFHNVVFNVIYQSAAIFKLSLTASNHVSNVTVNYNVTVERMNKMRSLQVS AVPAVLASNTMLALMASVMVDSAVEVAFLWTFGDGQQVLGQFKPPYNKSFQVPDPTVAQV LVEHNVTHTYTNAGEYNLTVLVSNAFENLTQQVPVSVRDTLPAVAISVSSSTLVAGWPVI FSLYPLPLPGGVLYMWNFGDDSPVLIQSQPMVNYTYTRTGTYHICLEVNNTVSSVVAHTD VHVFQELSGLSVQLSPAVEQGAPVVVSATVETGDNVMWTFDMGDGTVFTGPEATVQHIYL RAQNYTVTVNAASPAGHLTQSLPVRVFVLEVLRIEPATCIPTQPEAQLTAHVAGNPAHYL FDWTFGDGSSNTTVQGHPTVTHNFTRSGIFPLVLILSSHVNKAHYFTSVCVEPEVENVTL QPEQQFVQLGDEARLVACPWPHFPYRYTWDFGIEDTVPTHDWGPEATVVYRDPGSYLVTV TVSNNVSAVNDSALVEVQEPMVVTGIRVNGSHVLELQQPYLFSAMGHGHPATYLWELGDG AQLVGPEITHVYNSTGDFTIRVLGWNDVSHSEAWLNVTVKQRIRGLSINASRVVVPLNGS VSFSTTLDAGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVSTAQDSVF IYVLQFIEGLQVAGGGSGCCFPTNHTLQLQALVRDGTNISYSWTIQRDGSPALVGSGKSF LLTVLEASTYHIQLRATNMLGSVSANRTIDFVEPVEFLTVAASPNPAAVNRRITFVAELA GGSDVIYTWTLEEGLSLETSEPSTIHSFSTAGLYPVRVSARNQLGSVNVTIEVTVQVPVS GLSIRVSEPDSSFVAAGATVPFSGLLATGTNVSWCWAVPGGSKHGQHIAVGFPDAGVFSI QLNASNAVSWITALHNLTVEEPIRGLVLWASSKVVAPGQLVYFQILLAAGSAVTFHLQVG GANPEILFRPHFSHSFSRVGDHVVSVQAENHVSRGQAQVRVLVLEAVDGLQVPNCCELGM VTGTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAFN ELGGVNLTLTVEVQDAIQYVVLRSGRCFANRSARFEATTSPSPRRVAYHWDFGDGAPMQD TEEPWADHSYLLPGDYRVEVNASNLVSFFVAQATVTVQVLACREPEVDVALPLQVLMRRS QRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGPMARVALPGVDVSRPQLVVPRLALP VGHYCFVFVVSFGDTPLARSIQANVTVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDP NLEDDDQTPLSFHWACVAATQSETNACVLNFGPRGSSVVTIPRERLEAGIEYTFNLTVWK AGRKEEAASQTVLVRSGQVPIVSLECVSCKAQAVYEVSRSSYIYLEGHCHNCSSGSKHGR WAARTFSNKTLVLDETTTSTGSSGMRLVVRRGVLRDGEGYIFTLTVLGHSGEEEGCASIR LSPNRPPLGGACRLFPLDAVCALTTKVHFECVGWQDAEDASAPLVYALLLRRCRQGHCEE FCIYKGSLSTYGAVLPPGFQPGFEVGLAVVVQDQLGAAVVALNRSLAIVLPEPNSSMGLI PWLYSLTASVLPGLVRQADPQHVIEYSLALITVLNEYEQAPDVATEPNSEQQLRAQMRKN ITEILVSLRVNTVDDIQQITAALAQCMVSSRELVCRSCLKQTLHKLEGMMRILQAETTQG TVTPTTIADSILNITGDLIHLASSDIQSPQPSELGTESPSLMVASKAYNLSSALMCILMR SRVLNEEPLTLAGEEIVAQGKRSDPRNLLCYGNASSSGCHFSIPEAFSGALSNISDVVQL IFLVDSNPFPFGYINNYTVSTKVASMAFQTQAGTQIPIERLAKERAITVKVPNNSDQATQ SLHTPVGSAVIQPQASVSAVVTPDNSNPAAGLHLQLTYTVQSEHYLSEEPEPYLAVYLHS TPQPNEYNCSASRKISLEMLTGTDHRPYTFFIAPGTGYPGGSYHLNLTSHFHWSALEVSV GLYTSLCQYFSEEEMMWRTEGLVPLEDTSPSQAVCLTRHLTAFGASLFVPPSHIHFIFPE PASRVNYIVLLTCAMCLITYTIMVVILRRLDQLDVSWARVIPFCGKGGRFKYEILVKTGW GRGSGTTAHVGIMLYGADSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGNVWKIRVWHDN KGLSPAWFLQHIIVRDLQNAHSTFFLVNDWLSVETEANGGLVEKEVLAASDEALWQFQRL LVAELQRGFFDKHIWLSIWDRPARSRFTRVQRATCCVLLICLFLGANAVWYGVVGDATYS VRPLSSLIPPSVDTVAIGLVSSVVVYPVYLAILFLFRMSRSKVAGGPSPSPTVQQTLELD SCVDSSMLGSSFLTFSGLRAEAFTGQVKNDLLMDDSKSLACWPSSEGTLSWPDLLSDPSI VGSTLQRLARGQTGRGLGPEEDSLSLVSPSSPAKYFSASDEDLIQQVLAEGTSGLVVTQD TLVETDLLTGLSSVAGEKMEAPAIQRFGGSGPPGSGLTWEQPPLARLSRTGLVEGLQKRL MPAWCAPLAHGLSLLLVAVAVGVSGWVGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVL LEALYFSLVAKRLYPDEDDMLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVKRLHS MLRSLLVHMLFLLVTLLANYGDASCHNHAYHLQSAIKQELDSQAFLAITRSDEFWPWMSH VLLPYIHGNQSSPELGPPRLRQVRLQEALCPDPPSPGTHLCPAAAGFSTTDYGVGWQSVA HNGSETWTYTVPDLLGTWYWGYCAVYDSGGYVQELGLSLEESRTRLSFLQQHNWLDSRSR AVFVELTRYSPAVGLHAAITLRLEFPAAGRALAALSVHPFALLRFSTGLSLPLLTSVCLL LFAVYFSVAEARAWRREGCSHAMQPGAWAQWLLVTLTAAAALVRLAQLGTADRQWTRFLR GRPHHFTSFDQVAQLSTAARGLAASLLFLLLVKTAQQLRFVRQWSVFGKTLCRALPELLG ATLGLVILGVAYAQLAILLVSSCTDSLHNMVQALLVLCPSTRVPTLCPGESWNLSLLLCM GLWALRLCGALRLGAVLLRWRYHSLRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKE FRHKVRFEGMEPLPSRSSRGSKSSPEAPPPSGGSDSSHPSTSSSQLDAPNAGPGRPGGPG AQGEPEPEPSRLHAVFEALLTQFDRLNQATEDVYQLEQKLQRLQGCGSTQFSRSPHGSPF QSPKSALPSHLVQASEGMDPGIGHSRTSLWTKNRVCQHST NT seq 12903 nt NT seq  +upstreamnt  +downstreamnt atgccgcctggcgcgcccgcccggctggcgctggccctgggcctgggcctgtggctcggg gggctggcgggggcccccgggcgcggctgcgggccgtgcgcgcccccttgtctttgcggc ccggcgccgggcgcctcctgccgcgtcaattgctcaggccgtgggctgaggaagctaggg cccgagctgcgcatcccggccgacaccacagttctagatgtctcgcacaacttgctccag acgctggacgtcgggctcctggcaaacctttcggcactggtggaactagatataagcaac aataggatttctacattagaagaaggaatatttgctaatttatttaatttaagtgaaata aacctaagcaggaatccatttgagtgtgactgtggtctagtgtggctgaggcactgggca gaggagaagcaggttcttgtggtacaaccagaggaggcaacatgcacagggcctggcccc ctggctggccaacccctccttgggctgtccttggtagacaccggctgtggtgaggagtat gttgcctgccttcctgacaacagctcggacaccatggtgctggtggccttctccattgct cacgagggcccattggcacctgaggcttgcagcactttttgcttcttaggtggccagggc ctcgcagctctctcagagcagggccagtgtctgtgtgggacagcccagacccccaacatt tcagtggcatgcctctccctgtgttccaatcccctgcctcccacccctgcctgcgggggc cccaccttcctccagcatgtcttcccttcttccccagggaccaccctggtggggccccat ggacccctggcctctggccagccagcagccttccacatctctaccacctcccttcctctc agcactatatgctgggactttggtgatggctctcctaagctggacatggctggtcctgct gccacccaccgctatgtgctgcctgggcactatcatgtgacagcagtgctgactttgggg gctagttcaatcacactggagacagaggtgcaagtagaggtggcacctgctgctctggag cttgtgtgcccatcctctgtgcacagagatgagagccttgaattgagtatccggaaccgt ggaggctcagaccttgaggctacctatagcatcttagccttgggtgaggagccagtccaa gtagtacatccgctctgcccctcggacacggagatcttcccaggcaatgggcactgctac cgcctggtggcagagaaggcaccttggctgcaggcacaggagcagtgccaggcctgggct ggggctgccctggccatggtggacagtcctgcaatccagcacttcctggtttcccaggtt accaggagcctggatgtgtggatcggcttctcaactgtggagggagcagaggcaggcctg gcaccccagggtgaagccttcagcctggagagctgccaaaactggctgcctggggaacca cacccagccacggctgaacactgtgtgcggctggggcctgctggacagtgcaacacagac ctgtgctcagcaccacatagctacgtctgtgagctgcggcctggaggccccgtgtgggat gctgagaacttcctcatgggagtgcctggtgggggcctgcaggggcccctgattctactg acaccacaggaagccctcctgcccccccggtggcctgtggaggtcatggtgttccctggc ttaagcccaagccgtgaagccttcctcactacagccgagtttgagacccaggagcttggg gggcctgcccagttgcggcttcaggtgtaccggccttcaggaagggcaggggctccagaa aatagaagtgagcctgataacaggactgagccagtccccaggtgtatgccagagggatgc tggtgtcctggtgccagtctctgtatgccattggatgctgcctgccaccttcaagcctgt gccaatgagtccgtggtagagcctgggctccccagagccacctatgctctgtggagagag ttccttttctccgtgcccgcagggccccccacacagtacttggtgaccttccatgggcag gatgtccctgtgctccctggtgacctcattggcttacagcatgatgctggctcaggtgcc ctactgcagtgtcccctgacacccaaccaagctggctccaaggtcttgtacctctctacc aatgcctccaactggctggcccacctgcccaccttgctggatgatgctcggcctggccct gcctgtatcctgcagctggtcacagccactgaacgactcagccctcttctgggcctaagg tccaaccctggactgcagcatcctggacgctatgaggtccgggccacagtgggcaacaat gtatccacgtacaacctttcctgcagcttcaatgtggtctccccagtggctgggctccgg gtcatctacccggctactcttgatggccaactctatgtgccaaccagcggctcggtcttg gtgcttcaggtggattctggtgccaatgccacagccacagcttactggcctgggggcaat gtcagtgcacccttggagactgcctgccctaccatgctggatgccctcaagcctatctgt acccaagagaccaacaacactctgttttcagtgttggtacttcctgggctcagccaaggg gagcatgctgtggatgttgtagtgcagaacagcgctggccgggccaacctcaccctgaga gtaatggcagaggaacccattcgtggcctccatgctacgcctgttcccgaggcccgggta ctacagggtgccctggtgcgatacagccccatggtggaggccggttccaatgtggtcttt cggtggacaattgatgacaaacagtccctaactttccacaatgttgtcttcaatgtcatc tatcagagtgctgccatcttcaagctttcgctcacagcctccaatcacgtgagcaacgtc actgtgaactacaatgtcacggtggagcgcatgaataaaatgcggagcctacaggtgtct gcagtgccagctgtgctggcctccaacaccatgttggcactgatggccagtgtgatggtg gactcagctgtagaggtggctttcctgtggacctttggggatgggcagcaggtgctcggc cagttcaagcctccatacaacaagtccttccaggtcccggaccccactgtggcccaggtg ttggtggagcataatgttacacatacctacaccaatgcaggtgagtacaacctgactgtc ctcgtgtccaacgcctttgagaacctgacacagcaagtgcctgtgagtgttcgtgacaca ctgcctgctgtggccataagtgtgagtagcagcaccctggtggccggctggcctgtcatc ttctcactgtacccgctgcctttgcctggtggtgtcctatacatgtggaactttggggat gactcccctgtcctgatacagagccaaccaatggtgaattatacttatactagaacaggt acctaccacatctgcctggaggtcaacaacacagtgagcagtgttgtagcacacacagat gtccacgtcttccaggaactaagtgggctgagtgtgcaactgagcccagctgtggagcag ggagctcccgtggtagtcagtgctacagtggagacaggtgacaatgttatgtggacgttt gacatgggggatggcacagtgttcactggccctgaggctacagtgcagcacatatatctg cgagcacagaactatacagtgacagtgaatgcagccagccctgcaggccacttgactcaa agcctgcctgtgcgtgtttttgtcctggaggtactgcgtattgagcctgccacctgcatc cccactcagcctgaggcccaactgacagcccatgttgctgggaaccctgcccactacctc tttgactggacctttggagatggctcctctaacacaactgttcaggggcacccaacagtg acacataacttcacaaggagcggcatattccccctggtgttgatcctatcaagccatgtg aacaaggcacattacttcaccagtgtttgtgtagagcctgaggtggagaatgttaccctg cagcctgagcagcagtttgtgcagcttggggatgaagcccggctggtggcctgcccctgg ccccatttcccctaccggtacacgtgggactttggcatcgaagacactgttccgacccat gactggggccctgaggcaacagtggtctaccgagatccagggtcctacttggtgacagtc actgtgtccaacaatgtctctgctgtcaatgactcagctcttgtggaggtacaggagccc atggtagtcactggtatcagagtcaatggctctcatgtactggagctgcagcagccctac ctgttctctgccatgggccatgggcaccctgctacctacctgtgggagctgggggatggc gcacagcttgtgggccctgagattactcatgtctacaacagcacaggtgacttcaccatc agggtgttgggctggaatgacgtgagccacagtgaggcgtggctcaatgtcacagtgaag cagcgcatacggggcctgagcattaatgctagccgtgtggtggtgcccctgaatggcagt gtgagttttagcaccacactggatgcaggcagtgatgtgcactattcctgggtgctgtgt gaccgctgcacacccatccccgggggccccaccatctcttacaccttccgctcagtgggt acctttaacatcattgtgacggctgagaatgaggtgagcacagcccaggacagtgtcttc atctacgttctgcagttcattgagggcctgcaggtggcaggtggtggcagtggctgctgc tttcccaccaaccacacgctgcagctgcaggccctagtcagggacggaaccaacatttcc tacagctggaccatccagagggatggcagcccagcactagtaggtagtggcaagagtttc ttactgactgtgctcgaggccagcacctatcacatccagctgcgggccaccaatatgctg ggcagtgtctcagccaaccgcaccatagactttgtggagcctgtggagtttctgactgtg gctgcctctcccaacccagctgctgtcaatagaaggatcacgtttgttgctgagctggca ggtggcagtgatgtgatttacacttggaccttggaggaagggctaagcttggagacctct gaaccatctaccatccattccttttccacagctggcctctacccggtcagggtttcagct aggaaccagctgggctcagtcaatgtcaccattgaggtgactgtgcaggttcctgtgagt ggccttagcattagggttagtgaaccagacagcagctttgtagcagccggcgccactgtg cccttctcaggactcttggccacaggtactaatgtaagctggtgctgggctgtgccgggt ggcagcaagcatggccagcatattgctgtgggcttcccagatgctggggtcttctccatc cagctcaatgcttccaatgcagtcagctggatcacagctttgcacaacctcacagtagaa gaacccatcaggggcctggttctgtgggccagcagcaaggtggtagcacctgggcagctg gtctactttcagatattgctggcagctggctcagctgtcactttccacctgcaggttggt ggggccaatcctgagatactcttcaggccccatttctcccatagcttctcccgggttgga gaccatgtagtgagtgtgcaggctgagaaccatgtgagccggggtcaggcgcaggtgcgt gtcttggtgctagaggctgttgatgggctacaggtacctaactgctgcgagctgggcatg gtcacgggcactgagaagaactttacagctcgggtacagcggggctctcgagttgcctat gcttggtacttctccttgcagaaggtccagggtgactcactggtcattctctcaggccgt gatgtcacctacactcctgtggctgcagggctgctggagatccacgtgcgtgcctttaat gaactgggtggggtgaacctcacacttacagtggaggtccaggatgccatccagtatgtg gtgctgcgaagtggtcgctgctttgccaaccgctcggcccggtttgaggccaccacaagc cctagtccccggcgtgtggcttatcactgggacttcggggacggggctccaatgcaggac acagaggagccttgggctgaccactcctacttgctgcctggggactaccgtgtggaggtg aatgcctccaacctggtgagcttctttgtggcccaggccacagtgacggtccaggtgtta gcttgcagggagcctgaggtggacgtggccctccccctgcaggtattgatgcggcgctcc cagcgcaactacctggaggctcatgttgacctgcgtgattgtgtcacctaccagactgag taccgctgggaggtgtaccgtactgccagctgccagcgaccagggcctatggcacgggtg gccctgcctggcgtagacgtgagccggccccagctggtggttccacggctggcattacct gtaggccactattgctttgtgtttgtggtgtcatttggggacacaccattggcacggagc attcaggccaatgtaacagtggctgccgagcgcctagtgcctatcattgaaggtggctca tatcgcgtgtggtcagacacgcaagacctggtgctggatgggagcaagtcctacgacccc aacctggaggatgatgaccagacaccacttagcttccactgggcctgtgtggccgctaca cagagtgagaccaatgcgtgtgtcctgaactttgggccccgagggagcagtgtagtcacc atccccagggaacgtctagaggccggtatagaatacacctttaacctcaccgtgtggaaa gcaggcaggaaggaggaggctgccagccagacggtgctggtccgaagtggtcaggtgccc attgtgtcactggagtgtgtatcctgcaaggcacaggcagtatatgaagtgagccgcagt tcatacatatatctggaaggccactgtcataactgcagcagtggctccaagcacgggcgc tgggctgcacgaacctttagcaataagactctggtgctggatgagactaccacatccaca ggcagctcaggcatgcggctagtggtgcggcgtggtgtgctgcgggatggtgagggctac atcttcacgctcacagtgctgggccactcaggtgaggaggaaggctgtgcctccatccgc ctgtcacccaaccgccccccactggggggtgcatgtcgcctctttccactggatgcagtg tgcgccctcaccaccaaggtgcactttgaatgtgtgggctggcaggatgcagaagatgcg agtgccccactggtgtatgccctgctgctgcggcgctgtcgtcagggccactgtgaggag ttctgcatctacaagggtagtctctctacctatggggctgtgctgcctccaggattccag cctggctttgaggtgggactggctgttgttgtgcaggatcagttgggtgctgcagtggtt gccctcaacaggtctttggccattgtcctgccggagcctaatagctccatgggtcttatt ccctggctgtacagcctgactgccagtgtgctacctgggctcgtgagacaggctgacccc caacatgtcattgaatactcgctggctctcatcactgtgctcaatgagtatgaacaggct ccagatgtggccacagagcctaactcagagcagcagctgcgggcccagatgcgcaagaac atcacagaaatcctggtttccctgcgggtcaatactgtggatgatatccagcagatcacg gctgcgctggcccagtgcatggtgtctagcagagagctcgtgtgccgctcctgcctgaaa cagacactgcataagctggagggcatgatgcgcatcctgcaggctgagaccacccagggg actgttacacccaccaccattgctgacagcatcctcaatatcacaggtgacctcatccac ctggccagctcggacatacagagcccacagccttcagaactggggactgagtcgccctca ttgatggtggcatctaaggcctacaacctttcatcagccctcatgtgtattcttatgcgt tcccgcgtgctaaatgaggagcctctgaccctggcgggtgaagagatcgtggcacagggc aaacgctcagacccacgtaacctgctgtgctacggcaatgcttcaagctctggctgtcat ttctctatccccgaggccttcagtggggccctgtccaacatcagtgatgtggtgcagctc attttccttgtggattccaatccttttccctttggctacatcaacaattacactgtctcc accaaggtggcatccatggctttccaaacacaggctggcacccagatccccatagaacga ctggccaaagagcgtgccatcactgtgaaggtgcccaacaactcggaccaggctacccag agtctccacacccctgtggggtcagctgtcatccagccccaggcctctgtcagcgctgta gtcactccggacaacagcaaccctgcagcagggctgcacctgcagctcacctacacagtg cagagtgagcactacctgtctgaagagcctgaaccctacctggctgtctacctgcactca acgccccagcccaatgagtataactgctcagccagcagaaagatcagcctggagatgctc actggaaccgaccacaggccctataccttcttcatcgccccagggactggatacccaggt gggagttaccacctgaacctgactagccacttccactggtcagcactggaggtgtccgtg ggactgtacacatccctgtgccagtacttcagcgaggaggagatgatgtggaggacagag gggcttgtgcctctggaggatacttcacccagccaggccgtctgcctcacccgtcacctc actgcctttggtgccagcctctttgtgccacccagccatatccacttcatcttccctgag ccggcttctcgtgtgaactacattgtgctcctgacatgtgccatgtgccttataacctac accattatggttgtgatcctgcgcaggctggaccagctggatgtcagctgggcccgtgtc atccctttctgcggaaaggggggccgcttcaagtatgagatcctggtcaagactggctgg ggccgaggttcaggtaccacagctcatgtgggcatcatgctatatggagcagacagccgg agtggccaccgacatctggatggggacagggcctttcaccgcaacagcctggacatcttt aggattgccaccccacacagcctgggcaatgtgtggaagatacgggtgtggcatgacaac aaagggctcagccccgcctggtttctgcagcacatcatcgtcagggacctacagaatgcc cacagcaccttcttcttggtcaatgattggctgtctgtggagacagaggccaatggtggc ctagtagagaaggaggtgctggctgcaagtgatgaagctctgtggcagttccagcgcctc ctagtggccgaactgcagcgtggtttctttgacaagcacatctggctctccatatgggac aggccagctcgcagtcgctttactcgtgtacagagagccacctgctgtgtcctcctcatc tgcctcttcctgggtgccaatgcggtctggtatggggtcgtgggagatgccacctacagt gtacggcctctgtccagtctgatcccaccaagtgttgacacagttgccattggcttggta tccagtgtggttgtctaccctgtctacttggccatcctgtttctcttccgaatgtctagg agcaaggtggctggtggcccaagccccagccccacagtgcaacagacactggagctggat agctgtgtggactcatctatgctgggcagctccttccttacattctcaggcctccgcgct gaggccttcacaggacaggtgaaaaatgacttacttatggatgattctaaaagcctggcg tgttggccctccagtgaaggcacactcagttggccagacctgcttagcgacccatcaatc gtgggaagcaccctgcagcggttggcaaggggccaaacaggccgagggctgggcccagag gaagacagcctgtctctggtgagcccctcctcacctgccaaatacttctcagcatcagat gaagaccttatccagcaagtcctggctgaagggactagtggcctggtggtcacccaggac accctcgtagaaacggacctgctcactggcttgtccagtgttgctggggagaagatggag gcaccagcaatacagaggtttgggggcagtgggcctcctggctcaggcctgacctgggaa cagcccccactggcccggctctccagaacaggactggtggaaggtctacagaagcgactg atgcctgcttggtgtgccccactagcccatggtctcagtctactcctggtggctgtggct gtgggagtctcagggtgggttggtgccagcttcccccccagtgtgagtgtcatgtggctc ctctcgagtagctccagcttcctggcctcattccttggctgggagccacttaaggtcctg ctggaagccctttacttctcattggtggccaagcggctataccctgacgaagatgacatg ctggtggagagtccagccgtgacaccagtgagcgagcgtgtgccccgtgtgcggcctcct catggctttgctctcttcctggcaaaggaagaagctcggaaggtcaagaggctgcacagc atgctgagaagcctcttggtacacatgcttttcctgctggtgacactgttggccaactat ggggatgcttcctgtcacaaccatgcctatcatctgcagagtgccatcaaacaggagctg gatagccaagcctttctggccatcactcggtctgatgagttctggccatggatgtcccac gtgctgctgccctacatccacgggaaccagtccagccctgagctggggcccccgcggctg cggcaggtgcggctgcaagaagcactctgtccagacccccccagccctgggacacatctg tgcccagctgcagcaggcttcagcacaactgactacggcgttggctggcagagtgtagcc cacaatggctcagagacatggacttacactgtgcctgacctactgggcacctggtactgg ggttattgtgcggtctacgacagtggtggttacgtgcaggagctgggtctgagcttagag gagagccgcacacgtctgagcttcttgcagcagcacaactggcttgacagcaggagccgt gctgtgtttgtggagctcacacgatacagcccagccgtagggctgcacgctgccatcact ctgcgccttgagtttcctgctgccggccgtgccctggcagctctgagtgtccacccattt gcgctgctgcgcttcagcacaggactgtctctgccactgctcacatcggtatgtctgctg ctgttcgcagtctacttctctgtggctgaggctcgagcctggcgcagggagggctgttca catgccatgcagcctggagcctgggcacagtggctcctggtcacactgacagcagctgcg gcactggtacgtctggcccagctaggcactgctgaccgccagtggacccgcttcctccgt ggccgccctcaccatttcaccagctttgaccaggtggcacagttaagcactgcagcccgt ggcctggcagcttcactgctcttcctgcttttggtcaagactgcccagcagctgcggttt gtgcgccagtggtctgtgttcggtaagaccctgtgcagggccctgccggagctcctgggg gccacattgggcttggttatacttggagtggcctatgcccagctggctattctgcttgtc tcctcttgtacagattccctccacaacatggtccaggctctcctggtgctatgccccagt accagggtccctactctgtgcccaggcgagtcttggaacctgtcccttctgctatgcatg ggactctgggctctgcgtctgtgtggagctctgagactgggcgcagtccttctgcgttgg cggtaccactctctgcggggggaactctaccgcccagcctgggaaccccaggactatgag atggtagagctcttcctgcgcaggctgcgcctctggatgggcttcagcaaggtcaaggag ttccgccacaaagtccgctttgaagggatggaaccgctgccctctcgatcgtccaggggt tccaagtcttccccagaggcacctccacccagtggtggttccgactcttcacatccttcc acctcgtcgagccagctggatgcgccaaacgcaggcccaggccgcccaggtggcccaggt gcccagggagagcctgagccagagccctcccgcctccacgctgtattcgaggccctgctc acccagtttgaccgactcaaccaggccacggaggatgtctaccagctggagcagaagctg caaaggctccaaggctgtgggagcacccagttttctaggtcacctcacggtagccctttc caaagcccaaagtcagccctgcccagccaccttgtccaggccagtgaaggcatggaccca ggtataggccacagcaggacatcactgtggaccaagaacagggtctgccagcacagcact tag

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