Cavia porcellus (domestic guinea pig): 100733391
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Entry
100733391 CDS
T07777
Symbol
Ern1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc04140
Autophagy - animal
cpoc04141
Protein processing in endoplasmic reticulum
cpoc04210
Apoptosis
cpoc04932
Non-alcoholic fatty liver disease
cpoc05010
Alzheimer disease
cpoc05012
Parkinson disease
cpoc05014
Amyotrophic lateral sclerosis
cpoc05016
Huntington disease
cpoc05017
Spinocerebellar ataxia
cpoc05022
Pathways of neurodegeneration - multiple diseases
cpoc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100733391 (Ern1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100733391 (Ern1)
09143 Cell growth and death
04210 Apoptosis
100733391 (Ern1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100733391 (Ern1)
05012 Parkinson disease
100733391 (Ern1)
05014 Amyotrophic lateral sclerosis
100733391 (Ern1)
05016 Huntington disease
100733391 (Ern1)
05017 Spinocerebellar ataxia
100733391 (Ern1)
05022 Pathways of neurodegeneration - multiple diseases
100733391 (Ern1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100733391 (Ern1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100733391 (Ern1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cpoc01001
]
100733391 (Ern1)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100733391 (Ern1)
Protein kinases [BR:
cpoc01001
]
Serine/threonine kinases: Other
IRE family
100733391 (Ern1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
100733391
NCBI-ProteinID:
XP_013003837
Ensembl:
ENSCPOG00000000570
UniProt:
H0UU76
LinkDB
All DBs
Position
Unknown
AA seq
974 aa
AA seq
DB search
MPVRRLLLLLALLLPGPGIFASTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVVDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKV
MHINVAVETLRYLTFMPGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVTVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPRHRENVIPADSEKKSFEEVINLVDQTSETAPTAVSQ
DVEEKLARAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIISYPLSMHQQRQLQHQQFQ
KELEKIQLLQQQPPPFHPPGELTQDTELLDTSSPYSESSGTSSPSPSPRASNHSLHSNSS
ASRAGTSGSLEQDDEGEEASMVIVGKISFCPKDVLGHGAEGTIVYRGMFDSRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAYLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCFNPEKHEDVIARELIENMIAMDPQQRPSAKRVLKHPFFWSVEKQLQFF
QDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPAEVQETLGSLPDDFVRYFTSRFPHLLSHTYRAMELCSHERLFQPYYH
EPPEPQPPVTPDAL
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgccggtccggcgtctgctgctgctgctggcgctgctgctgcccggccctgggattttt
gcaagtaccagcacagtgactttgcctgaaaccttgctgtttgtgtcaaccttggatgga
agtttgcacgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagatcca
gtccttcaggtcccaacacacgtggaggagcctgccttccttccagatcccaatgatgga
agcctgtatacacttgggggcaagaataatgaaggcttgacgaaacttccctttaccatc
ccagagttggtacaggcatccccatgccgaagctcagatggaatcctgtacatgggtaaa
aagcaggacatttggtacgtcgttgacctcctgactggtgagaagcagcagactttgtcg
tcagcctttgcagatagtctctgcccgtcaacctcgcttctgtatcttggacgaacagaa
tacactatcaccatgtatgacaccaaaacccgagagcttcgctggaatgccacctacttt
gactacgcagcctccctgcctgaggatgatggggactataagatgtcccattttgtgtcc
aatggcgatggcctggtggtgactgtggacagtgaatctggggatgtcctgtggatccaa
aactatgcctcccctgtagtggccttctacgtctggcagcgggagggtctgaggaaggtg
atgcacatcaacgttgctgtggagaccctacgctacctgaccttcatgcccggggaggtg
ggccgcatcaccaagtggaagtacccatttcccaaggagaccgaggccaagagcaagctg
acgcctaccctgtatgttggaaagtactccaccagcctctacgcctccccctctatggtg
catgagggggtcaccgttgtgccccgaggtagcactcttcctttgttggaaggcccccag
acggatggtgtcaccattggggacaagggagagtgtgtgatcacacccagcacagacctc
aagtttgaccctgggctcaaagggaagagcaagctcaattacttgaggaattactggctc
ctgataggacaccatgaaaccccactgtctgcatccaccaagatgctggagagatttccc
aacaatctgcccagacaccgggaaaatgtgattcctgctgactcggagaaaaagagcttt
gaggaagttatcaacctggttgaccagacttcagaaactgcacccactgctgtgtctcag
gatgtggaggagaagttggctcgtgctcctgccaagcctgaggcccctgtggactccatg
ctcaaggacatggccaccatcatcctgagtaccttcctcctggtcggctgggtggccttc
atcatctcctaccccctgagcatgcaccagcagcggcagctccagcatcagcagttccag
aaggagctggagaagatccagctcctgcagcagcagccgccgcccttccacccacctgga
gagttgacacaggacactgagctcctggacacgtccagcccttactcagagagctcaggg
accagcagccccagcccatccccgagagcctccaaccactcactgcattccaacagctct
gcctctagggctggcaccagcggctccctggagcaggatgatgagggtgaggaagccagt
atggtgatagttggaaaaatttcattctgccccaaagatgtgctaggccatggagctgag
ggcaccattgtgtacaggggcatgtttgacagccgcgatgtggctgtgaagaggatcctt
cccgagtgtttcagctttgccgaccgtgaagtccagctgctgcgagaatcagacgagcat
cccaatgtgatccgctacttctgcacagagcgggaccggcagttccagtacattgccatt
gagctgtgtgcagccaccctgcaggagtacgtggagcagaaggacttcgcccaccttggc
ctggagcccatcaccttgctacagcagaccacctcaggcctggcatatctccactccctc
aacattgttcacagagatctgaagccccacaacattctcctctccatgcccaatgcacat
gggaggatcaaggccatgatctctgactttggcctctgcaagaagttagcagtgggcagg
cacagttttagccgccgttctggggtccctggcaccgaaggctggatcgctccagagatg
ctgagtgaagactgcaaggagaaccctacctacacggtggacatcttctccgcgggctgt
gtcttttactatgtcatctctgagggcagccacccttttggcaagtccctgcagcggcag
gccaacattctcctgggcgcctacagtcttgactgcttcaacccggagaagcatgaagat
gtcatcgcacgtgagttgatagaaaacatgatcgcgatggatccccagcagcggccttca
gcgaagcgcgtgctgaaacaccccttcttctggagcgtggagaagcagctccagttcttc
caggatgtgagtgaccggatagaaaaggaatccctggatggcccgattgtgaggcagttg
gagagaggcgggcgagccgtggtgaagatggactggcgggagaatatcaccgtgcccctc
cagacagatttgcgtaaatttagaacctacaagggtggctccgtcagagatctcctgcga
gccatgagaaacaagaagcaccactaccgggagctccctgcggaagtgcaggagacgctg
ggctccctccccgatgacttcgtgcgctacttcacgtcacgcttcccccacctcctgtca
cacacctaccgtgccatggaattgtgcagccacgagagactcttccagccctactaccac
gagcccccggaaccccagcccccagtgactccagatgccctctga
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integrated database retrieval system
