Cavia porcellus (domestic guinea pig): 100733410
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Entry
100733410 CDS
T07777
Symbol
Acaca
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00061
Fatty acid biosynthesis
cpoc00620
Pyruvate metabolism
cpoc00640
Propanoate metabolism
cpoc01100
Metabolic pathways
cpoc01212
Fatty acid metabolism
cpoc04152
AMPK signaling pathway
cpoc04910
Insulin signaling pathway
cpoc04922
Glucagon signaling pathway
cpoc04936
Alcoholic liver disease
Module
cpoc_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100733410 (Acaca)
00640 Propanoate metabolism
100733410 (Acaca)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100733410 (Acaca)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100733410 (Acaca)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100733410 (Acaca)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100733410 (Acaca)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100733410 (Acaca)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100733410 (Acaca)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100733410 (Acaca)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100733410 (Acaca)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100733410
NCBI-ProteinID:
XP_003469510
Ensembl:
ENSCPOG00000006043
UniProt:
H0V6W7
LinkDB
All DBs
Position
Unknown
AA seq
2393 aa
AA seq
DB search
MPKWRCNDERMWWSTLISILRASSFWRRISAQTVRITRALRAYFKRIMDEPSSLAKPLEL
NQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASGSSDTLSDLGISSLQDGLAS
HIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKC
MRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELI
LDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTA
GIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKAS
EGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISL
FGRDCSVQRRHQKIIEEAPAAIATPVVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSF
YFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFE
NSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFA
DSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWL
DRLIAEKVQAERPDTMLGVVCGALHVADVNLRNSISNFLHSLERGQVLPAHTLLNTVDVE
LIYDGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDR
YRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTVTA
SESGCIHYVKRPGAALDPGCVIAKMQLDNPNKVQQAELHTGSLPRIQSTALRGEKLHRVF
HYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLN
VEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQ
RYRSGIRGHMKAVVMDLLRQYLKVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQ
VTKKNLLVTMLIDQLCGRDPTLTDELLTILTELTQLSKTTNAKVALRARQVLIASHLPSY
ELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVY
VRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTH
VASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTS
LYDEDKVPRDEPIHILNVAIKTDCDIEDDSLAAMFREFTQQNKATLVDHGIRRLTFLVAQ
KDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTA
IPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEA
MDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEL
KINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLI
NTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLT
YTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYRIGSFGP
QEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYL
TPQDYKRVSALNSVYCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDE
IITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQ
IMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKAPYD
PRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTV
ELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGM
KDMYDQVLKFGAYIVDSLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRES
RGSVLEPEGTVEIRFRKKDLVKTMRRVDPVYIRLAERLGTPELSPVERKELENKLKEREE
FLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIH
NANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIK
YISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEIVQILSTMDSPST
NT seq
7182 nt
NT seq
+upstream
nt +downstream
nt
atgcccaaatggaggtgcaatgatgagaggatgtggtggtccacactgatatcaatcttg
agggctagttctttttggagacggatatctgcccagacagtaagaattacgagagctctc
agagcttatttcaaaagaataatggatgaaccatcttccttggccaaacctctggagctg
aaccagcactcaagattcataattggttctgtgtctgaagataattcagaagatgagatc
agcaatttggtgaagttggacctactggaggagaaggaaggctctttgtcaccagcttct
ggcagctcagatacactctctgacttgggaatctctagcttacaggatggcctggcctca
cacataaggtctagtatgtctgggttacacctcgtaaaacaaggtcgagacaggaagaaa
atagattctcagcgagattttactgtggcttctcctgcagaatttgttactcgttttggg
ggaaataaggtgattgagaaggttcttattgctaataatggcattgcagcagtgaaatgt
atgagatctatccggcggtggtcgtacgaaatgtttcgaaatgagcgtgcaattcgattt
gttgtcatggtcacacctgaagaccttaaagcaaatgcagaatatattaagatggctgat
cattatgtgccagtgcctggaggaccaaacaacaacaactatgcaaacgtggaattaatt
cttgacattgctaaaagaatcccagtacaagcagtgtgggcaggttggggtcatgcttct
gagaatcccaagctcccagaacttctcttgaaaaatggcattgcctttatgggtcctcca
agccaggccatgtgggctttgggcgataagattgcatcttccattgtagctcaaactgca
ggtatcccaactcttccctggagtggcagtggtcttcgtgtggactggcaggaaaatgat
ttttcgaaacgtatcttaaatgttccacaggaactctatgaaaaaggttacgtgaaggac
gtggatgatgggctgaaggcagcagaagaagttggatatccagtaatgatcaaggcctca
gaaggaggaggagggaagggcatcaggaaagtcaacaatgcagatgactttcctaacctc
ttccgacaggttcaagctgaagtccctggatctcctatatttgtgatgagactagccaaa
caatctcgtcacctggaggtgcagattctagcagatcagtatggcaatgccatctctttg
tttggccgtgactgctctgtacaacgaaggcatcagaagattattgaagaggctcctgct
gctattgctactccagtagtatttgaacacatggaacagtgtgcggtgaaacttgccaaa
atggtgggttatgtgagtgctggaactgtggaatatctgtacagccaggatggcagcttc
tactttctggaactgaatcctcggctacaggtggagcacccttgtacagaaatggtggct
gatgtcaatctccctgcagcacaactccagattgccatggggatccctctatttagaatc
aaggatatacggatgatgtatggggtatctccctggggtgatgctcctattgattttgaa
aattctgctcatgttccttgcccaaggggtcatgttattgctgcccggatcactagtgaa
aatccagatgagggttttaagccaagctcaggaacagttcaggaactaaatttccgtagc
aacaagaatgtttggggttatttcagtgttgctgctgcaggaggacttcatgaatttgct
gattctcagtttggtcactgcttttcctggggcgaaaacagagaagaagcaatttcaaat
atggttgtggctttgaaggaactatctattcggggtgactttcgaactacagttgaatac
ctgatcaaattgttagagactgaaagctttcagttgaacagaattgatactggctggctg
gacagactgatagcagaaaaagtacaggcagaacgacctgatactatgttgggagtcgtg
tgtggggctctccacgtggcagatgtgaatctgcggaatagcatctccaactttcttcac
tccttagaacggggtcaagtcctacctgctcatacacttctgaacacagtagatgttgag
cttatctatgatggaatcaaatacgtacttaaggtaactcggcagtctcccaactcctac
gtggtgatcatgaatggctcatgtgtggaagttgatgtccatcggctgagtgacggagga
ctgctcttgtcatatgacggcagtagttacaccacatacatgaaggaagaagttgataga
taccgcattacaatcggcaataaaacctgtgtgtttgagaaggaaaatgacccatcagta
ttgcgttcaccttctgctgggaagttaatccaatacattgtggaggatggaggccatgtg
ttcgctgggcagtgctatgctgagattgaggtaatgaagatggtgatgaccgtaacagct
tctgaatctggctgcattcattatgtcaagcgacctggagcagctcttgaccctggctgt
gtaatagcaaaaatgcaattggacaaccccaacaaggttcagcaggctgagcttcacact
ggtagtctgccacggatccagagcacagcacttagaggcgagaagctccatcgagtgttc
cactatgtcctggataatctggtcaatgtaatgaatggatactgccttccagatcctttc
tttagcagcagggtaaaagactgggtagagcgcttgatgaagaccctcagagatccctcc
ctgcctctccttgaattgcaagatatcatgaccagtgtctctggccgtatccctctcaat
gtggaaaagtcaatcaagaaagaaatggctcaatatgctagcaatatcacatcagtcctc
tgtcagtttcccagccaacagattgccaacatcctagatagtcatgcagctacattgaac
cggaaatctgaacgggaagttttctttatgaacactcagagcattgttcaactagtacag
agataccgaagtggcattcgaggccacatgaaggctgtggtgatggatctgctccggcag
tacctgaaagtagagacacagttccagaatggtcactatgacaaatgtgtgtttgccctt
cgtgaagagaacaaaagtgacatgaacactgtactgaactacattttctctcatgctcaa
gtcaccaaaaagaatcttctggtcacaatgcttattgatcagttatgtggccgggaccct
actctcactgatgagctgctgactatcctcactgaattaactcaactcagtaagaccacc
aatgccaaagtggcacttcgagcccgtcaggttcttattgcctcccatttgccatcatat
gaacttcgccataaccaagtagagtctatttttctatcagctattgacatgtacggacat
cagttttgcattgagaatctgcagaaacttatcctatctgaaacttctatttttgatgtc
ctaccaaacttcttctatcacagcaaccaggtagtgaggatggcagctctggaggtatat
gttcgaagagcttatattgcctatgaacttaacagtgtacagcaccgccaacttaaagac
aatacctgcgtggtggaatttcagtttatgctacccacatctcacccaaacagagggaac
atccccacgctaaacagaatgtccttctcctccaacctcaaccactatggcatgactcat
gtagctagtgtcagcgacgtgctgttggacaactccttcactccaccatgtcagcggatg
ggtggaatggtctctttccgtacttttgaagattttgtcaggatctttgatgaagtgatg
ggctgcttctgtgactcccctccccaaagtcctacattcccagaggcgggtcatacatct
ttatatgatgaagacaaggtcccccgggatgaaccaattcacattctgaatgtggccatt
aagactgactgtgacattgaggatgacagtctggcagctatgttcagagagtttacccag
caaaataaagctaccctggttgaccatgggattcggcgccttactttcctggttgcacaa
aaggattttagaaaacaagtcaactgtgaagtggatcaaagatttcatagagaattccct
aaattttttactttccgagcaagagataagtttgaggaggatcgtatctatcgtcacctg
gagcctgctctggcttttcagttagagctgaaccggatgagaaattttgaccttactgcc
attccttgtgctaatcacaagatgcacctgtatcttggggcagccaaggtagaagtgggc
acggaagtgacagactacaggttctttgttcgtgcaattatcagacattctgatctggtc
actaaggaagcttcttttgaatacctgcaaaatgaaggggaacggctactgctggaagcc
atggatgagttagaagttgcttttaataatacgaatgtccgtactgactgtaatcacatc
ttcctcaactttgtgcccacagtcatcatggacccctcaaagattgaggaatctgtgcgg
agcatggtaatgcgctatggaagtcggttgtggaaattgcgcgtcctccaggcagaactg
aaaatcaacattcgcctgacaccaactggaaaagcaattcccatccgccttttcctgaca
aacgagtctggctattacttggacatcagcctgtacaaggaagtaactgactccaggaca
gcacagatcatgtttcaggcatatggagataaacagggtccactacatggaatgttaatc
aatactccgtacgtgaccaaagatctccttcagtcgaagagattccaggcacagtcctta
ggaacaacatatatatatgatattccggagatgtttcggcagtccctgatcaaactctgg
gagtctatgtccactcaagcattccttccatcaccccctctgccctctgacatgttgaca
tatactgaactggtgttggatgatcaaggtcagctggtccacatgaacaggcttccagga
ggaaatgagattggcatggtagcttggaaaatgaccctcaaaagtcctgagtatccagaa
ggccgggatatcattgttattggaaatgacatcacataccgaattgggtcctttgggccc
caggaggatttgctgtttctcagagcttctgaacttgcccgggcagagggtattccacgc
atctatgtagcagccaacagtggagcaagaattggactcgcagaagaaatccgccatatg
tttcatgtggcctgggtagatcctgaggatccttacaagggatacaagtatttatatttg
acccctcaagattataagagagtcagtgctctcaactctgtctattgtgaacatgtggaa
gatgaaggagaatccaggtacaagataacagatattattggaaaagaagagggacttgga
gcagaaaaccttcgaggttcagggatgattgctggagaatcttcattggcctatgatgaa
atcatcaccatcagcctggtgacatgccgggccattggaattggggcttaccttgttcgt
ctaggacagagaaccatccaagttgagaattctcacttgattttaacaggagccggtgcc
ctcaacaaagtcctcgggcgggaagtatatacttccaataaccagcttgggggcatccag
atcatgcacaacaatggagtgactcacagcactgtttgtgatgactttgaaggagtcttt
actgtcctgcattggctgtcatatatgcctaagagtgtgcacagttcagttcctcttctc
aactccaaggatcctatagacagaatcatcgagtttgttcctacaaaggccccttatgat
cctcggtggatgctagcaggccgtcctcacccaacccagaaaggtcagtggttgagtgga
ttttttgactatggatctttctcagagattatgcagccatgggcacagactgtggtggtt
ggtagagccaggctaggaggaatacctgttggcgtagttgctgtggaaacccgaacagta
gaactaagtatcccagctgatccggcaaacctggattctgaagctaagataattcagcaa
gctggccaggtttggttcccagactctgcgtttaagacctatcaggctatcaaggacttc
aaccgtgaaggactccctttgatggtctttgccaactggagaggcttctctggtgggatg
aaagatatgtatgaccaagtgctgaagtttggtgcttacatcgtggatagcttgcgggag
tgctcccagccagtgatggtttacattcctccgcaggctgagctgcggggtggctcctgg
gttgtgattgaccccaccatcaaccccaggcacatggagatgtacgctgaccgagaaagc
aggggatcagttctggagccagaagggacagtagaaatcagattccgcaaaaaggatctg
gtgaaaaccatgcgtagggtggatccagtctacatccgcttggctgagcgattgggcacc
ccagagctaagtccagtggagcggaaggagcttgaaaataagctaaaggagcgggaagaa
ttccttattcccatttaccatcaggtagccgtgcagtttgctgacttgcatgacacacca
ggccggatgcaagagaagggtgttattaacgacatcctggactggaaaacatctcgcacc
ttcttctactggcggctgaggcgtctcctgctagaggacctggtcaagaagaaaatccac
aatgctaacccagagctgactgatggccagatccaggccatgttaaggcgctggtttgtg
gaagtggaaggaacagtgaaggcctatgtttgggacaataataaagatctggtggagtgg
ctggagaagcagctgacagaggaagatggtgttcgctcagtaatagaggagaacatcaaa
tacatcagcagagactacgtcctcaagcagatccgcagcttggtacaggccaatccagaa
gttgccatggattccattgtccatatgacccagcacatctcacccactcagcgagcggaa
attgtacagatcctctccacgatggattccccttccacgtag
DBGET
integrated database retrieval system
