Cavia porcellus (domestic guinea pig): 100734840
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Entry
100734840 CDS
T07777
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc01521
EGFR tyrosine kinase inhibitor resistance
cpoc01522
Endocrine resistance
cpoc04010
MAPK signaling pathway
cpoc04014
Ras signaling pathway
cpoc04015
Rap1 signaling pathway
cpoc04066
HIF-1 signaling pathway
cpoc04068
FoxO signaling pathway
cpoc04081
Hormone signaling
cpoc04114
Oocyte meiosis
cpoc04140
Autophagy - animal
cpoc04144
Endocytosis
cpoc04150
mTOR signaling pathway
cpoc04151
PI3K-Akt signaling pathway
cpoc04152
AMPK signaling pathway
cpoc04211
Longevity regulating pathway
cpoc04213
Longevity regulating pathway - multiple species
cpoc04510
Focal adhesion
cpoc04520
Adherens junction
cpoc04550
Signaling pathways regulating pluripotency of stem cells
cpoc04730
Long-term depression
cpoc04913
Ovarian steroidogenesis
cpoc04914
Progesterone-mediated oocyte maturation
cpoc05200
Pathways in cancer
cpoc05202
Transcriptional misregulation in cancer
cpoc05205
Proteoglycans in cancer
cpoc05214
Glioma
cpoc05215
Prostate cancer
cpoc05218
Melanoma
cpoc05224
Breast cancer
cpoc05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100734840 (Igf1r)
04014 Ras signaling pathway
100734840 (Igf1r)
04015 Rap1 signaling pathway
100734840 (Igf1r)
04066 HIF-1 signaling pathway
100734840 (Igf1r)
04068 FoxO signaling pathway
100734840 (Igf1r)
04151 PI3K-Akt signaling pathway
100734840 (Igf1r)
04152 AMPK signaling pathway
100734840 (Igf1r)
04150 mTOR signaling pathway
100734840 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
100734840 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100734840 (Igf1r)
04140 Autophagy - animal
100734840 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
100734840 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100734840 (Igf1r)
04520 Adherens junction
100734840 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
100734840 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100734840 (Igf1r)
04914 Progesterone-mediated oocyte maturation
100734840 (Igf1r)
09156 Nervous system
04730 Long-term depression
100734840 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
100734840 (Igf1r)
04213 Longevity regulating pathway - multiple species
100734840 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100734840 (Igf1r)
05202 Transcriptional misregulation in cancer
100734840 (Igf1r)
05205 Proteoglycans in cancer
100734840 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100734840 (Igf1r)
05214 Glioma
100734840 (Igf1r)
05218 Melanoma
100734840 (Igf1r)
05215 Prostate cancer
100734840 (Igf1r)
05224 Breast cancer
100734840 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100734840 (Igf1r)
01522 Endocrine resistance
100734840 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cpoc01001
]
100734840 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
cpoc04090
]
100734840 (Igf1r)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100734840 (Igf1r)
Protein kinases [BR:
cpoc01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100734840 (Igf1r)
CD molecules [BR:
cpoc04090
]
Proteins
100734840 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
100734840
NCBI-ProteinID:
XP_003475316
Ensembl:
ENSCPOG00000005399
UniProt:
H0V5D0
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKSPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTEYQECCHPECLGSCH
APDDDTACVACRHFYYAGICVPACPPGTYRFEGWRCVHRDFCANIPNAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLRFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDAEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERRRRDVAQMANTTMSSRSRNTTVADTYNATDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EARPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLSRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKTTYENFIHLIIALPVAILLIVAGLAIMLYVFHR
KRNSSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEVENSPILAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSVKDELEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPPPDRH
SGHKGENGPGPGVLVLRASFDERQPYAHMNGGRTNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttctctct
gctgcgctctcgctctggccgacgagtggagaaatctgtgggccgggcatcgacatccgc
aatgactatcagcagctaaaacgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcaccgtc
atcaccgagtacttgctgctgttccgggtcgctggcctcgagagcctcggagacctcttc
ccgaacctcaccgtcatccgcggctggaaactcttctataactacgccctggtcatcttc
gagatgaccaacctgaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaagaatgctgacctgtgctacctctccacagtggactggtcgctgatc
ctggatgcggtgtccaataactacattgtggggaacaagtccccaaaggaatgtggagac
ctgtgtccagggaccatggaggagaaaccattgtgcgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaatcgctgccagaaaatgtgcccaagtgcctgcggg
aagcgtgcgtgcaccgagtaccaggagtgctgccatcctgagtgcctgggcagctgccat
gcacccgacgacgacacggcctgtgtggcctgcagacacttctactatgctggcatctgc
gtgcccgcctgtccacccggcacctaccgcttcgagggctggcgctgtgtgcaccgagac
ttctgcgccaacatccccaatgctgagagcagtgactccgagggcttcgtcatccatgac
ggggagtgcatgcaggagtgtccctcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgcgaggaagaaaagaagacgaaaacc
attgactctgtgacttctgctcagatgctccaagggtgcaccatcttcaagggcaacctg
ctcattaatatccgacggggcaataacattgcgtcggaactggagaacttcatggggctc
attgaggtggtgactggctacgtgaagatccgccattcccatgccttggtctccttgtcc
ttcctgaaaaaccttcgcctgatcctgggggaggagcagctggaagggaactactccttc
tacgtcctggacaaccagaacctgcagcagctgtgggattgggaccaccgcaacctcacc
atcaaatctgggaagatgtactttgctttcaatcccaaactgtgtgtctctgaaatttac
cgcatggaagaagtgacggggacgaaagggcgccagagcaaaggggacataaacaccagg
aacaacggggaacgagcctcctgtgaaagtgacgtattgcgtttcacctccaccaccaca
tcgaagaaccgcattatcatcacctggcaccggtaccggcccccagactacagggatctc
atcagcttcactgtttactacaaggaggcaccgtttaaaaatgtcaccgagtatgatggg
caggatgcttgtggctccaacagttggaacatggtggacgtggacctgcctcctaacaag
gacgcggagcctggcatcctactgcatgggctgaagccctggacacagtacgcggtctat
gtcaaggccgtgaccctcaccatggtagagaacgaccacatccgtggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgtcctttcggca
tccaactcctcttctcagctcatcgtcaagtggaaccccccatctctgcccaacggaaac
ctgagttattatatcgtgcggtggcagcggcagcctcaggacagctacctataccggcac
aattactgctccaaagacaaaatccccatcagaaagtatgcggatggcaccatcgatgtc
gaagaggtcaccgagaaccccaagactgaagtatgtggtggcgagaaagggccttgctgc
gcttgccccaaaaccgaagccgagaagcaggccgagaaggaggaggccgagtaccggaaa
gtgtttgagaatttcctgcacaactccatcttcgtgccgaggcctgaaaggaggcggcga
gatgttgcgcagatggccaacaccaccatgtccagccgcagcaggaacaccacggtggct
gatacctacaatgccacagatccagaggagctagagaccgaataccctttctttgagagc
agagtggataacaaggaaagaactgtaatttcaaacctccggccttttaccttgtaccgc
attgacatccacagctgtaaccatgaggctgagaagctgggctgcagcgcttctaacttt
gtttttgcaagaaccatgcccgcagaaggagcagatgacattcctggcccggtgacgtgg
gaagcaaggcctgaaaactccatctttttaaagtggccagagcctgagaatcctaatgga
ttgattctaatgtacgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtg
tccagacaggaatacaggaaatacggaggggccaagcttagccggctaaacccagggaac
tatacagcccggattcaagctacctcgctctctgggaatgggtcgtggacagatcctgtg
tttttctatgtcccagccaaaacaacgtatgaaaacttcatccatctgatcatcgctctg
ccagtcgccatcctgttgattgtggcaggcttggcgataatgctgtacgtcttccatagg
aagagaaacagcagcaggctggggaatggagtgttgtacgcctctgtgaacccggagtac
ttcagtgctgcggatgtgtacgttcctgatgagtgggaggtagcgcgagagaagatcacc
atgagccgggagctggggcaaggctcctttgggatggtctacgaaggagtggctaaaggt
gtggtgaaagacgagcctgagacccgggtagccatcaagacagtgaacgaggccgcaagc
atgcgtgaaaggatcgagtttctcaatgaggcctctgtgatgaaggagttcaactgtcat
catgtggtgcgactgctaggcgtggtgtcccagggccagcccacactggtcatcatggag
ctgatgacgcggggggatctcaagagctatctcaggtctttgaggccggaagtagagaat
agccccatcctggcacctccaagcctcagcaagatgatccagatggccggagagattgca
gatggcatggcatacctcaacgccaacaagtttgtccacagagaccttgctgcccgcaat
tgcatggtagctgaagatttcacagtcaaaattggagattttgggatgacgcgagatatt
tacgagacagactactaccggaaaggagggaaagggctgctgcctgtgcgctggatgtct
cctgagtccctcaaggatggagtcttcaccactcattcggacgtctggtccttcggggtc
gtcctctgggagatcgccacgctggctgagcagccataccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggtggcctcctggacaaacccgacaactgcccagacatg
ctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcgtcaaagacgagctggaggccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggacctggagcccgagaacatg
gagagcgtcccgctggacccatcagcctcctcgtcctccctgccgccgcccgacagacac
tcaggacacaagggcgagaacggcccgggccccggcgtgctggtgctccgcgccagcttc
gacgagagacagccttacgcgcacatgaacggaggccgcacgaacgagagggccttgccg
ctgccccagtcgtcaacctgctga
DBGET
integrated database retrieval system
