KEGG   Crocodylus porosus (Australian saltwater crocodile): 109317893
Entry
109317893         CDS       T07440                                 
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
cpoo  Crocodylus porosus (Australian saltwater crocodile)
Pathway
cpoo04270  Vascular smooth muscle contraction
cpoo04350  TGF-beta signaling pathway
cpoo04510  Focal adhesion
cpoo04520  Adherens junction
cpoo04530  Tight junction
cpoo04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:cpoo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    109317893 (ROCK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109317893 (ROCK1)
   04520 Adherens junction
    109317893 (ROCK1)
   04530 Tight junction
    109317893 (ROCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109317893 (ROCK1)
 09150 Organismal Systems
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    109317893 (ROCK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cpoo01001]
    109317893 (ROCK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cpoo03036]
    109317893 (ROCK1)
Enzymes [BR:cpoo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     109317893 (ROCK1)
Protein kinases [BR:cpoo01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   109317893 (ROCK1)
Chromosome and associated proteins [BR:cpoo03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    109317893 (ROCK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Pkinase_C Cortex-I_coil DUF1192 APH
Other DBs
NCBI-GeneID: 109317893
NCBI-ProteinID: XP_019402399
LinkDB
Position
Unknown
AA seq 1377 aa
MSTGEGFEPRLEKIDAMLRSPRSEVNVDCLLDGLDALVYDLDFPALRKNKNIDNFLNRYK
DTVNKMRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSSRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFTNSPWVVQLFYAFQDDHYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNEISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYNNRQYLSVSEENSNDNRTSS
NMDKSVLENMQKTIYELEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRKNLE
STVSQIEKEKILLQHKINEYQRKTEQENEKRRNLENEVSTLKEQLEDLKKLSQHSHIANE
KITQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERCRVLESTKLQ
VEKDYYQLQAALEAERRDRNHGSERIGELQARITSLQEEVKHLKNNLEKVEAERKQAQDM
LNNSEKEKNNLEIDLNYKLKTLQERLDQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEK
KVKEERAAREKAENRIVQIEKQCSMLDFDLKQSQQKLEHLIEQKERLEDEVKNLTLQLEQ
EANKRVLAQNDLKMQASEADNLKSSEKQLKQEINTLLETKRLLEFELAQLAKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNKETQRKIQELQNEKETLAAQLDLAETK
AESEQLARALLEEQYFELTQESKKAASRHRQEIIDKDGIISRLEETNNTLTKDVEFLTKE
NTEVNEKIKKQEEEFKLKKEEEISNIKVQYEKNLNTERTLKTQAVNKLAEIMNRKDFKID
RKKANIQDLRKKEKENRKLQLDLNQEKEKFNQMVVKYQKELNEMQAQLAEESTYRNELQM
QLDSKESDIEQLRSKILDLQQGMDSTSVASLQADETDGNVSESRLEGWLSVPNKGNIKRH
GWKKQYVVVSSKKILFYNDEKDKDQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIF
QILYANEGECRKELEVESTQPAEKTNFLNHKGHEFIPTLYHFPANCEACAKPLWHVFKPP
PALECRRCHVKCHKDHLDKKEELIAPCKVSYDVTSARDMLLLASCQDDQKKWVNHLVKKI
PKTPPASFVRSSPRTMSARSSANQSFRKAVKNTSGKTRSKECGSVGEITHSENSSYC
NT seq 4134 nt   +upstreamnt  +downstreamnt
atgtcgacgggggaaggcttcgagccccgcttggagaagatcgatgcgatgctaaggagc
ccccgttccgaggtcaacgtggactgtctgctggatggattagatgccttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatatcgataacttcttaaacagatataaa
gacacagtaaataaaatgagagatttgcgtatgaaagctgaagattatgaagtggtgaag
gtgattggtagaggtgcatttggggaagtgcaactggtaaggcataaatcttcaaggaag
gtgtatgctatgaagctcctgagcaagtttgagatgataaaaagatcagattctgcattc
ttctgggaagaaagggatattatggcttttactaatagcccctgggttgttcagttattt
tatgcattccaagatgaccattacctgtacatggtgatggaatacatgcctggtggggac
cttgtgaatttaatgagcaactatgatgttcctgagaaatgggcaagattttatacggca
gaagttgttcttgcattggatgccattcattcgatgggctttattcacagagatgtgaag
cctgataacatgctgctagataaggctggtcatttaaaactagcagattttggtacttgt
atgaagatgaacaaggaaggtatggtacgatgtgatacagctgttggaacaccggattac
atttcccctgaagtattgaaatcccagggtggtgatggttactacggacgagaatgcgac
tggtggtcagttggagtttttttgtatgaaatgcttgtaggcgatacacctttttatgca
gattctttagttggaacatatagtaaaattatgaaccataagaactctctgactttccct
gatgataatgagatttctaaagaagcaaaaaacctgatttgtgccttcttaactgacagg
gaagtgaggttaggacgaaatggtgtagaagaaattaaaagacacctcttcttcaaaaat
gatcagtgggcttgggaaactcttagagacactgttgcaccagttgtgcctgatttaagt
agtgacattgacactagtaactttgatgatttggaagaagacaagggagaggaagaaaca
ttccctatacctaaagcatttgttggcaaccagctaccttttgtaggatttacatactac
aacaatcgccagtatttgtctgtctctgaagagaattccaatgataacaggacaagctcc
aatatggataaaagtgtgctggaaaacatgcagaaaacaatctatgagttggaagagcag
ctacataatgaaatgcagttgaaagatgaaatggagcaaaagtgcagaacttcaaacata
aaactagataagataatgaaggaacttgatgaagagggaaatcaaagaaaaaacttagaa
tcaacagtatcgcagattgagaaggaaaagattctgttgcaacataaaataaatgaatac
caaagaaaaactgaacaagagaatgaaaaaagacgcaatttagaaaacgaagtgtctacg
ttaaaagaacagttagaagacctgaaaaaacttagtcagcattcacatattgcaaatgag
aagataacacaattacagaagcaactagaagaagccaatgatttgctgaggacagaatca
gatacagcagtaagactgagaaagagccatacagaaatgagcaagtctgtaagccaatta
gaatcgctaaacagagaactacaggagaggtgccgtgttttggagagcacaaaattgcaa
gtggagaaggattattatcaactacaagcagctttggaagcagaacgaagggaccgaaac
catggatctgaaaggataggagagctacaagctcggattacatctttacaagaagaggtc
aagcatcttaaaaataatcttgaaaaagtggaagcagaaagaaaacaggcacaggatatg
cttaataattctgaaaaggagaaaaataacttggaaatagatttaaactacaagctcaaa
acattacaagagcggctagaccaggaggtaaatgagcataaagtgactaaagcacggtta
actgacaaacatcaatcaattgaagaggcaaaatcagttgcgatgtgtgaaatggaaaaa
aaagtcaaggaagagagggccgcaagagagaaagcagagaatcgaatagttcagattgaa
aaacaatgttccatgctggactttgacctgaagcagtctcagcagaagctggaacatctt
attgaacaaaaggagagactagaggatgaagttaagaatctaacacttcagctggagcaa
gaggcaaataaacgagttctggcacaaaatgacttgaagatgcaagcttctgaggcagac
aacttgaagagttctgagaagcagctgaaacaggagatcaatacattgctggaaacaaag
agattattggaatttgagttggctcaacttgctaagcaatatagaggaaatgaaggtcag
atgcgggaacttcaggatcaacttgaagctgaacagtatttttcgacactttacaaaact
caggttaaggagcttaaagaagaaattgaggaaaagaataaagaaactcaaaggaaaata
caggaattgcaaaatgaaaaagaaactctggctgcacagctggatctggctgaaaccaaa
gctgagtcagaacagttggctcgagctctcttggaagaacagtattttgaacttactcag
gagagcaagaaagcagcatcaagacatagacaagaaattattgataaggatggcattata
agtcgactggaagaaacaaataatacattaaccaaagatgttgagtttctaacaaaagaa
aatacagaggtaaacgaaaaaatcaagaagcaggaagaagagtttaaactgaagaaagaa
gaggaaatcagtaacattaaagtgcagtatgagaagaatcttaacacggaaagaactctt
aaaacgcaggctgtcaacaagttggctgaaataatgaatcggaaagattttaaaatagat
agaaaaaaagctaacatccaagatttgaggaaaaaagagaaggaaaaccgaaagctacag
ttggaccttaaccaagagaaagaaaaattcaatcagatggtagtaaaataccaaaaagag
ctcaatgaaatgcaggcgcaactagcagaagagtctacatataggaatgagcttcagatg
cagctggatagtaaagaaagtgatatagaacagttgcgaagcaaaattttggacctccag
caaggaatggactctactagtgttgcaagcctccaggcagatgaaaccgatggaaatgtt
tcagagtcaagactagagggctggctttcagtaccaaacaaaggaaacataaagcgacat
ggctggaagaagcagtacgttgtagtgagcagtaaaaagattttgttctataatgatgaa
aaggacaaggaccagtccaatccatccatggtactagatatagataaactgttccatgtc
cgacctgtaacacaaggagatgtatatagagcagaaactgaggaaatccctaaaatattc
cagattttgtacgctaatgagggtgaatgcaggaaagaattggaagtagaatcaacacag
ccagcagaaaagacaaattttctaaatcacaaaggtcatgaatttattcctacattatac
cattttccagccaactgtgaggcctgtgccaaacccctctggcatgtttttaaaccccct
cctgcactggaatgtcgaagatgccatgttaagtgccacaaagaccacttagataaaaag
gaggaattaattgctccatgcaaagtgagttacgatgtaacttcagcaagggatatgttg
ctattggcatcctgtcaggatgaccagaagaaatgggtgaatcatttagtaaagaagatc
cccaagacaccaccagccagttttgtccgttcttcccctagaactatgtctgcaagatcc
tcagcaaatcaatcattccgaaaagctgttaaaaatacttctggaaaaactaggtcaaag
gagtgtggatctgtgggggagattacccattcagagaactccagttattgctaa

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