Citrobacter portucalensis: FOB25_07620
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Entry
FOB25_07620 CDS
T06238
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
cpot
Citrobacter portucalensis
Pathway
cpot00260
Glycine, serine and threonine metabolism
cpot00261
Monobactam biosynthesis
cpot00270
Cysteine and methionine metabolism
cpot00300
Lysine biosynthesis
cpot01100
Metabolic pathways
cpot01110
Biosynthesis of secondary metabolites
cpot01120
Microbial metabolism in diverse environments
cpot01230
Biosynthesis of amino acids
Module
cpot_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
cpot_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
cpot_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
cpot00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FOB25_07620 (thrA)
00270 Cysteine and methionine metabolism
FOB25_07620 (thrA)
00300 Lysine biosynthesis
FOB25_07620 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FOB25_07620 (thrA)
Enzymes [BR:
cpot01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FOB25_07620 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FOB25_07620 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QET56311
LinkDB
All DBs
Position
complement(1613277..1615739)
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LANISDAERIFSELLAGLAAEQPGFPLAQLKAFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGLLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIP
ADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASSD
DDDLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRAGISVVLITQSSSEYSISF
CVPQGDCTRAQRAMQDEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQTWLKKKHIDLRVCGVANSKALLTNVHGLNLENWQSELESAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRFAAAKSR
RKFLYDTNVGAGLPVIENLQNLLSAGDELQRFSGILSGSLSFIFGKLDEGMSFSQATTLA
REMGYTEPDPRDDLSGTDVARKLLILARETGRELELSDIVIEPVLPKEFDDSGDVSAFMA
KLSQLDDVFAARVAKARDEGKVLRYVGNIEEDGVCRVKIDAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagagcgctttctgcgggtt
gccgatattctggaaagcaatgccagacaggggcaggtcgcgaccgttctctctgccccc
gcaaaaattaccaaccatctggtggcaatgattgagaagaccatcggtggtcaggatgct
ttagctaatatcagcgacgccgaacgcattttctccgagctgctggcgggtcttgccgcc
gagcaaccaggttttccgctggcgcagctcaaagcctttgttgaacaagaatttgcccag
attaagcacgtcctgcacggcatcagcctgctgggacagtgcccggacagtatcaatgcc
gcgcttatctgccgtggtgaaaaaatgtcgattgctatcatggccggcctgttggaagca
cgcgggcataacgtaacggtcatcgacccggtggagaaattgctggctgtcggccattac
ctcgaatctaccgttgatatcgccgaatctacgcgccgcatcgccgccagccgtattcct
gcggaccacatgattctgatggcagggtttaccgctggaaatgaaaaaggtgagttagtg
gtgttggggcgtaatggctctgactactctgccgccgtactggccgcctgtttgcgtgcc
gattgttgtgaaatctggaccgatgtcgacggtgtatatacttgcgatccgcgtcaggta
cccgacgcccgactgcttaagtcgatgtcttatcaggaagcgatggagctttcttacttc
ggcgctaaagtgctgcacccgcgcaccattacccctattgcccagttccagatcccgtgc
ctgattaaaaataccggcaatccgcaagcgcccggtacgctgatcggtgccagcagtgat
gacgatgatttgccggtaaaaggtatttctaacctcaataacatggcgatgtttagcgtt
tccggccctggaatgaaaggcatggtgggcatggcggcgcgcgtttttgccgcaatgtcg
cgtgcgggcatctcggtagtgctgatcacccaatcctcttctgaatacagcatcagcttc
tgcgtcccgcagggcgactgcacgcgtgcacaacgcgccatgcaggatgaattctacctc
gagctgaaagaaggcctgctggagccgctggcggtgactgagcgtctggccatcatctct
gttgttggcgatggtatgcgcaccctgcgcggcatctcggcgaagttctttgccgcgctg
gctcgggcgaacatcaatattgtagcgatagcccagggctcgtctgagcgttctatttcg
gtggtggtgaataacgatgacgcgaccaccggcgtacgcgtgacccatcaaatgctgttc
aacaccgaccaggtgattgaagtgtttgtgattggcgtaggcggcgtgggcggtgcgctg
ctggagcagcttaaacgtcagcaaacctggctcaaaaagaagcatatcgatctgcgcgtg
tgcggtgtggcgaactcgaaggccctgctgaccaacgtccacggtctgaatctggaaaac
tggcagtcggagctggagagcgcgaaagagcctttcaaccttgggcgcttaattcgtctg
gtgaaagaataccatctgctcaatccggtgattgtcgactgtacgtcaagccaggcggta
gcggatcaatatgccgacttcttgcgtgaaggcttccacgtggttacgccgaacaaaaag
gccaacacgtcgtcgatggattactatcatcagctgcgttttgccgccgcgaagtctcgt
cgtaaattcctgtacgacaccaacgtgggcgcgggcttgccggttattgaaaacctgcaa
aatctgctcagcgcaggtgatgaactgcaacgtttttcaggcatcctttctggctcactg
tcgtttattttcggcaagctggatgaaggcatgagcttctcgcaggccaccaccctggcg
cgtgagatgggctataccgaacccgatccgcgtgacgatctttccggtacggacgtggcg
cgtaagctgctgatcctggcccgtgaaaccggtcgtgagctggagctttctgacattgtc
attgagccggtcctgccaaaagagtttgatgactccggtgatgtttccgcgtttatggcg
aaattgtcgcagctggatgacgtctttgccgcgcgcgtggcgaaagcccgtgatgaggga
aaagtattgcgctatgttggcaatatcgaagaggacggcgtttgtcgcgtgaaaattgat
gcagtagacggcaacgatccgctgtttaaagtgaaaaacggtgaaaacgcgctggcgttc
tatagccactattatcagccgttaccgttggttctgcgcggatatggcgcgggtaacgat
gtgacggcggcgggcgtctttgccgacctgctacgcaccctttcatggaagttaggagtc
tga
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