Corynebacterium resistens: CRES_0790
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Entry
CRES_0790 CDS
T01538
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
crd
Corynebacterium resistens
Pathway
crd00300
Lysine biosynthesis
crd00550
Peptidoglycan biosynthesis
crd01100
Metabolic pathways
crd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
crd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CRES_0790 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CRES_0790 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CRES_0790 (murF)
Enzymes [BR:
crd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CRES_0790 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEI09146
UniProt:
F8E007
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Position
977350..978864
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AA seq
504 aa
AA seq
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MIELTVGKIAEITGGELVDGADPDTKVLGPVEFDSRRIKPGGIFMALPGAQVDGHDYAAS
AAEQGAALLVVGKRVGAPALVAPSVELRQEASNASAFEHDTQGHGAAVLAAIDRLARFNT
DALVAEHGMTVVGVTGSAGKTSTKDLIGAILREAGPTVAPPGSFNNEIGLPYTALRAEEG
TKYLVSEMSARGVGHIRHLTEVTPPNIGVVLNVGSAHLGEFGSRDAIAQAKGELVEALPE
NGLAVLNADDDKVAAMAARTHARVVRFSTSQETCEWAGREVAVDYYASDIQLDEVARARF
ALHHPYGDPVAVELGVFGAHQVSNALAAAAVGMECGMSATDVARALNGHVAASVNRMDVR
TRARDGVTIINDSYNANPESMRAGIDALAYTASGRDGAESWAVLGQMGELGDDATEAHAD
LGHSLSQRRIRHAVIVGNGVNQQALAHAAREDGVDTHVVEDADAAVNFLDLSLRKSDVVL
VKASYSDGLWAVAEGLLLGEEEGA
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgattgagctaactgttggaaaaatcgccgaaattaccggcggagaattagtagatggc
gccgatccggatacgaaagttttagggccggtagagttcgacagccgccgaatcaagcca
ggaggcatttttatggccctccctggtgctcaagtggacgggcacgattacgcggcctcg
gccgccgagcaaggtgcagcgctgctcgtggtcgggaaacgcgtgggtgcgcccgcgttg
gttgcaccgagtgtggagttgcgccaggaagcctccaatgcctccgccttcgaacacgat
acgcagggtcacggcgctgcggttctggctgcgatcgaccggttggcacgttttaatacc
gacgccctcgtggctgaacacggaatgaccgtggttggggtcacgggttccgccggtaaa
acttccacaaaagacctcatcggcgctattttgcgcgaagcggggccaactgtggcgcca
cccggaagcttcaataatgagatcgggctgccctatacagcactgcgcgctgaagaggga
acgaagtacttggtctcggagatgtccgcccgtggggtcgggcatattcgtcacctcact
gaggtaaccccgccgaacatcggagtggtgttgaacgttggttccgcgcacctcggcgag
ttcggcagccgtgatgctatcgctcaagcaaagggtgaattggtggaagctctgcccgaa
aatgggttggcggtattgaacgctgatgatgacaaagtcgcggccatggcagcgaggact
catgcccgtgttgtgcgattctccacctcgcaagaaacttgtgagtgggcggggcgtgaa
gtggcagttgactactacgccagcgatatccaattggatgaggtcgcccgcgcgaggttc
gctctgcaccatccgtatggcgatcctgtagctgttgagctcggagttttcggtgcccac
caggtttccaatgccctcgctgcggctgcagtgggaatggaatgtgggatgtccgcaacc
gatgtggcacgggcgttgaacgggcacgtcgccgctagtgttaaccgcatggatgtgcgc
acgcgagctcgcgatggtgtgacaatcatcaacgattcttacaacgcaaaccccgagtca
atgcgggctggtatcgatgccctcgcatataccgcttccggtcgtgacggggcggaaagc
tgggcggttctggggcagatgggagagctcggtgacgacgcgaccgaagcccacgcggac
cttgggcactccttgagccaacgccgaattcgccatgcagtgatcgtgggtaatggagtg
aaccaacaggccctggcacatgcggcacgcgaggatggtgtggatacccacgttgttgaa
gatgcagatgcagccgtgaatttcctggacttaagtttgcgcaagtccgatgttgttttg
gttaaggcctcgtactccgatggtctttgggcggtagccgagggcttgctcctcggtgaa
gaagaaggagcgtaa
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