Citrobacter rodentium: ROD_00011
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Entry
ROD_00011 CDS
T01145
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
cro
Citrobacter rodentium
Pathway
cro00260
Glycine, serine and threonine metabolism
cro00261
Monobactam biosynthesis
cro00270
Cysteine and methionine metabolism
cro00300
Lysine biosynthesis
cro01100
Metabolic pathways
cro01110
Biosynthesis of secondary metabolites
cro01120
Microbial metabolism in diverse environments
cro01230
Biosynthesis of amino acids
Module
cro_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
cro_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
cro_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
cro00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
ROD_00011 (thrA)
00270 Cysteine and methionine metabolism
ROD_00011 (thrA)
00300 Lysine biosynthesis
ROD_00011 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
ROD_00011 (thrA)
Enzymes [BR:
cro01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
ROD_00011 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
ROD_00011 (thrA)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
PEG10-RTL1_C-capsid
DUF6247
Motif
Other DBs
NCBI-ProteinID:
CBA35022
UniProt:
D2TGQ2
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All DBs
Position
313..2775
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFAELLTGLAQVQTGFPLAQLKAFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGLLEARGHHVTVIDPVEKLLAVGHYLESTVDIAESTRRIAAARIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDDLPVKGISNLNNMAMFNVSGPGMKGMIGMAARVFAVMSRSGISVVLITQSSSEYSISF
CVPQADCARAQRALQDEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQTWLKSKHIDLRVCGVANSRALLTNVHGLNLENWQAALAEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRFAAAKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQKFSGILSGSLSFIFGKLDEGMSLSEATKVA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPETFDNSGDVAAFMA
KLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacgtcagtggcaaatgcagaacggtttctgcgggtt
gccgatattctggaaagcaatgccaggcaggggcaggtagcgaccgtactttctgccccc
gcaaaaattaccaaccacctggtggcgatgattgaaaagactatcggcggtcaggatgcc
ttacccaatatcagcgatgccgaacgtatttttgccgaactgctgaccgggcttgcacag
gtccagacgggatttccgctggcgcagttgaaggccttcgttgagcaagaatttgcgcag
attaagcatgttttgcatgggatcagcctgctgggccagtgtccggacagcattaacgcc
gcgcttatctgccgtggcgaaaagatgtcgattgccatcatggccgggctgttggaggcg
cgcggccaccatgttaccgttatcgatccggtcgaaaaactgctggcggtagggcactat
ctggaatccaccgttgatattgccgaatccacccgccgtatcgccgccgcgcgcattcct
gccgatcatatggtgctgatggcgggttttaccgccgggaatgagaaaggcgagctggtg
gtgctggggcgtaatggttccgattattccgccgcggtgctggccgcctgcctgcgcgcc
gactgttgcgagatctggaccgacgtggacggcgtttatacctgcgacccgcgccaggtg
ccggatgccaggctgctgaagtcgatgtcttaccaggaagcgatggagctttcctacttc
ggcgccaaagtccttcaccctcgcaccatcaccccaatcgctcagtttcagatcccttgc
ctgattaaaaacaccggcaacccgcaggcgccaggtacgcttatcggcgccagccgcgat
gaggacgatctgccggtgaagggcatctccaacctcaacaatatggcgatgttcaacgtc
tccggtcctggcatgaaaggtatgatcgggatggcggcgcgcgtctttgcggtgatgtcc
cgctccgggatctcggtagtactgatcacccagtcctcgtcggaatacagcatcagcttc
tgcgtgccgcaggcggactgcgcccgcgcccagcgcgcgttacaggatgagttttatctt
gagttaaaagaaggtctgctggagccgctggcggtgaccgagcgcctggcgattatctcc
gtggtcggcgacgggatgcgcacgctgcgcggtatctcggcgaagttttttgccgcactg
gcgcgcgccaacatcaatattgtcgcgatcgctcagggctcctccgagcgctccatttcg
gtggtggtgaacaatgacgatgccaccacgggcgtgcgcgtgacccatcagatgctgttc
aataccgatcaggtgattgaagtgtttgtcattggcgtcggcggcgtcggcggcgcgttg
ctggagcagctcaagcgccagcagacctggcttaagagcaaacatatcgatctgcgcgtc
tgcggggtggcgaactcacgagcgctgctgaccaacgtgcatgggctgaacctggagaac
tggcaggcggcgctggcggaagcgaaagagccgtttaacctggggcgcttaattcgcctg
gtgaaagaataccatctgcttaacccggtgattgtcgactgcacctccagccaggcggtg
gcggatcagtatgctgatttcctgcgcgaaggtttccacgtggttacgccgaataaaaag
gcgaatacctcatcgatggactattaccaccagctgcgttttgcggcggcgaaatcgcgg
cgtaaattcctctacgacactaacgtcggcgcgggcctgccggtaatcgagaacctgcaa
aacctgctgaacgccggtgacgagctgcaaaaattctccgggattctgtccggttcgctc
tcctttattttcggcaagcttgatgagggaatgagcctctctgaggccacgaaagtggcg
cgtgaaatgggctacaccgagccggatccgcgtgatgacctttccgggatggatgtggcg
cgtaagctgctgatcctcgcccgcgaaaccggacgcgagcttgaactttctgacatcgtt
atcgagccggttttgccagaaacctttgacaattccggcgatgtcgctgcgtttatggcg
aagctgccgcagcttgatgacgcttttgccgcccgcgtggcgaaagcccgtgatgagggc
aaagtgttgcgctatgttggcaatattgaagaagacggcgtctgccgggtaaaaattgcc
gaggtcgatggtaacgatccgctgtataaagtgaaaaacggcgaaaacgcgctggcgttc
tacagccactattatcagccgctgccgctggtgctgcgcggctacggtgcgggcaacgac
gttacggcggcaggggtattcgccgacctgttgcgtaccctctcatggaagttaggagtt
taa
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