Caenorhabditis remanei (nematode): GCK72_001218 Help Entry GCK72_001218      CDS       T09085                                  Name (RefSeq) hypothetical protein   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism crq  Caenorhabditis remanei (nematode) Brite KEGG Orthology (KO) [BR:crq00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:crq04121]     GCK72_001218 Enzymes [BR:crq01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      GCK72_001218 Ubiquitin system [BR:crq04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     GCK72_001218 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 DNA_PPF UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  9810963 NCBI-ProteinID:  XP_053591526 UniProt:  A0A6A5HQ93 LinkDB All DBs Position I:6490342..6505113 Genome browser AA seq 4220 aa AA seqDB search MNSRRLAIGLARYVQQDTNQEVKGEIIAAFIYRLRVVVNYKSKDVDEICEAMRILIQRLV DLPPVTFAPEVWMPLMAAISEGGIEPQWRMMMETVDVSSLPPPTEPNDPESDFEDEIDLQ LTTSPKYYEQITSICKEFVLKYGLTRRVFAAILGTDLSETMEKMIDQKWDSLKIQTSNES ASQASYLMERNIFDVFSEMKDHEMFAKELFYASLARILKRLQEHQKPSQDSEDVSFYESS FQIFDEVLKKMWPYLSKTDSSIKKNSMKIFEKLLSICPNNVLVQKLTEKFVDTCGWLKIS AEDICEEMEPRLWKVVGSLVARLLDLKKTIPYEIVSYAIAVHITQEVTLASPEDYAPDDF EALCEQPPGGSKKEMFLRSMVDATRASLLQVLIYLRTSKSSSDVVQFMRDYYSELVFSQE TLIMHASIDMFRESTFRDSIKSEDILSIVDSIIDTPAIVSMVLVICGIKDVKTAKQALEK TLIRMANDLEDEDQKREGYVNHLHESSSFWACVAKYADRNILDKAAKRFVEVAIDSPDIR TATLSADIFLTILKLELVSDAEKLSEDAVICNAKFSNWDMEESRFRQVGNKLVECNMAKR PKYAQVPLFTLQHLQEVDSLPMRDLIYTVTLMQFLKTKEGMELHKQFYENYPGLDEIFEN FHSREHKIRLCSRLLGEFAKIVSENEKGSLIFSLDHENVLNWLEEIGIIDSPIISEKLID LTFHVEVWHALNFLQFESTECHFDDVQTFGRIWMTNVMEVIPDKTLREVEDQITIMLRNQ YEKQGYKMKALREKRFNGKFPKYPKPEPLEPQILSMHNRIGIWLTKKKVEEFADESTKLF TWLIGVCSGQKSYGDVVTAEAKKILAKLYPDQQKQEDIKHYFGMSALLNGIGICKEEEGK FSFRPMFIRIYQEVVSRDMTTWEAGYSMEVISKRLGGFHEWLEDVNEEKLEKDNGHHLQV IQKLSHHCWFKLRTIEVAELDNTTPDHILLTLRKFSEVIASRMDKIINWLIPTLSPFTLA SRLDLLLEIIFLFPEIVEKYRKQIESYFFKLFDLFLKEEYIDGLVNNPEFKIQTTDKYLS STLNTKREYYLKDPTQNKLFRVPDLLMLISKYGSKNVQIYCLKKIGEALAILPGKILENQ EVLRGNKNIEENSEKRVACDVIVLSEFLGYFNCLYSQISMETLSEPSEETIMKTFMLLDT GSRSKNETNKRKTSSGLPRHHQDHIDMKYCTFKSTGNKFTSQHWYNCYTCNMMESTGVCS TCAVNCHRGHELAYSKKGAFFCDCGSKPCDAMKGADHYPNAMNSLRGQFPDNSIQKTSPK PRDVFVYFFEFLKTKDDDFEELKNSLKAVQKEFQKAQNDLEKVLESIDYANRKALNVTEH QRSVVESMKNMDRVVLEEKEEFMSPLDAAGHFLPIRGSDSMVQDRGLSITLRQRELADII KLDDGTELLVMIPDSVQSCLQLHYMDTRTHLLQGMHCLRTETEQIPFSPVSLDVSGNRLV VCGTYEIYALRFSPQGTVIDRAHIKLLENGSSGSMNGNPVKKARFCPEIEGDTRKKQLIA VATMQYIRVYDLTLHETNFVEEMVLTTGNVEDVLILNPVNGNIRVLVLSSSGYLYEHNIS DCTADNNSIFLTNVVNTPGMDMNGDGVSLHYSSKFNLLFVSLDSALYVARLPEPTGNSQA PIYDWKPMNIKWPVEVWREASGIIACLSKEITDQVMYFHPTVDKIMIQKTQVNRPIMTFF MMTSSKNQSIYSVMIFPNLPTCEIWESSWENVHDLWIADVPSERFAIEVVEQKTVPKPLD KEDLVLLAEQCEPIGTVEWSCRDIEMFYTHTELNHRLSISESMPITVVQQTHFTLTARVT NSRQIVRMIRLEVEGPTGPEYLKIGNTRYTVSTRNAKVYDLRLTREESLTLDHRNITIEV IPKTNQNTVKLKSLKLYGCDRNAMDEIQPRFERQPVLNTPNRLVYSILEFPGEDVQWVEK VAESHLSRKLNHPSVCSISTKSILKCHPKIDEKLFQIIDRSYLQEWKSLANWTEESGFSE MRMHHVEHLLDRMEAVRTRWPYFYQTLKQEFGAVTCFVELMRDEMRKMPLHRCQMMAQAI VKVVFGMLSYGTDESEKLIHVFLDIFTDNSTYHLANDLRSAVQETFSRYDNVLKQEKQLI EGKDKKELIRIGNTGLAPFYGAPRVLAKTPANLMISNVTDTLPLEEIEKTTWLDQIISLL LEKLSRSKSTSTWQNISDSPAYNLSRVLASCVAICDPKIIGSHFSRLIRLISYDANEIYP FSEKTFPNYSLLRSVELLLFVCLEKRGEEKKENLEMLDSIVNELQTVGIRDLCFNVLEKV IPEWKERGPATFARNSSESHRKVWLPHVPLVSSSANPPNANVMNWPSSLEDAYIIACTDL VLLIPQHLQELDRRKSVPRDDRWIQKLCQLANLSNGCSAYRQCKKLLLAMCYNDETKYKI MRDKYKMQELLQQLVNKYLNVSKEVGGHQQLTEIVDILASITKLAMIRPDMWRDVCSTYT TWLLRLACYTTKVVASQVVELLIVAVRDSSVGGQLSIQLADSIIEAQNGEFIEKIIKRFL IGKDEQLRWTLHGMLRSVIQLASRQNQCSIVKKLYNTVYPMVENLGVQGAQLVDLIATYA PRVFSSAELVSMTQSEISTIQKIGDTLDKDGYQGMYELMSHLGLGWKSIQFDRNPCLVCF TSRGIHDVVKMTTIKSDTRYSANTMIYKLLSNYEISKVIIKLSDVKKSKAIRKVSLYYSA KSVESVELKLHPELWRKCAVVNVGENETIINLSLAVPVVTSSLIIEFDEVTDQRSSSQLH CPRCSGPVRTHSGVCDSCGENAFQCMKCRSINYVEKEPFLCQSCGYCKYARIELSAVCRA LPGAQHITCDAERGQCVQEITQLLTKMETTKTKLTGYRAVCESLYLKNRPLPPYKLHVEN NHASEFFETNGTMSTEQLAFQSVTNPMSNLAVTIKTLHTELCQQTQQLMYLHEELNRYDH ASEVSIVFHKSQNTSYYSTSESCFGCLCNQLLHSIALLHSACDDENALNLLLSFDSTIER LGILAQTYETLREEVEELLVRLMFGRTDVTSKIEKLIENGDVNLSVMVKSLMYAADPTWQ QKLKLLVRFAIEKRDENSCLQALMVLNKYLEATKTVSMDERKKIKVTKKEGVVKWLTSDE DWNDCCSIASTSTAPPPSTPSNPYEWISECLFSQWMSVRSAANQLLINLSRQQFHEPIAL LLLCENLAKLTTLPSADCDQFMSSCHTIIDSSVNTKTRLFVQQFHVYLIRKIHEECANLH GQKITLSTDNTFGERLRCFVELLSLLLSGSYVENVLLKAGADDLLIFLLHSTIFLKRMMT RRTRAIDSSRTALEKLLKRVSCRDGTKLMSVCVDSLKLVKDTSTLGIIVGVMMEIMNPQQ ETEESFLIQIEKDVAQEDFLQGRMTHNPYNSNDLGMGPLMRDIKNKICRDTEMIALMEDD NGMELLVNGNIISLSLSVREVYDRLWKRTNNGSPMLIVYRMRGLMGDAVETFIENFGVAE NSEEDDEEDEQLVRMTNCLTQCGGIDKLMDLMATNVESSSGRFLLGHLRKMFERIVKIPV GRRVLIERRMVERMMSVVRTCCADPTNESKVAIGMELYKVVEFVVSDKHVQDILCGIKEE DANWWFDLFEKRGNEEGSVTELHRKTAQILDQMTSSIGNIVMGSDASENVLVGMYSRILK WDVIDAGVPPSDIQARQRISRRDQTIMMTEQLANITANILPSTYGARLKQKILDSGVIAT TCQYLMKDLPNLYQPTESPEWKVFLSQPSLKLILTLLAGLARGHQASQKEIAKTTLKLMH RLEQVASDNSIGTLAENVIEALNEDEEVKNQIKMVRDETEKKKKQMAMMNREKQLMKMRM KVGTGGQIKVSSRTLHNEPSIDDTDSLSCCICRESVIRGSQASGVYAFAAIDQESARTCT VSMMVMVHLDCHKNAIRGGGGGRAVDEWTRSKLHNAGAKCNVITPIAMGTTTDEIWIEAI HRYEIDIGRVSGLAHVVVNRNFVFIDICKLVNRFIHKRSFSLQSEGGGRESNMQYLAILH LFGVSLPADAAELEISSSDQRLIGFLFTELTTESWNDQKNDVLRATLHDAQTNGPIATYQ DAKPILMTWAFVDAYFNKVIKITGDDRLEWLREHLVETINKTRGFVDDFDSNVLPCEGLA EFCDVTGALLNELAVFLPDN NT seq 12663 nt NT seq  +upstreamnt  +downstreamnt atgaacagccgtcgattggcaatcgggcttgctcgatatgttcaacaggacaccaatcaa gaagttaagggagaaataatagctgcatttatctatagactacgggttgtggtaaattac aaaagcaaagatgttgacgaaatctgcgaagcgatgcgaattctcatccaaagacttgtc gatcttcctccagtaacgttcgcacctgaagtatggatgcccttaatggcagcaatatca gaaggtggaatcgaaccacaatggagaatgatgatggaaacagttgatgtctcaagtctt cccccacccacagaaccaaatgatcctgaatctgattttgaagatgaaattgatctacaa ttaacgacttctccgaaatattatgaacaaataacatcaatttgcaaagaatttgtactt aaatatggtctgactcggagagttttcgcagcaattttgggtacagatttgagtgaaaca atggagaaaatgattgatcagaaatgggattcgctgaaaattcagacatcgaatgagtca gcaagtcaagcaagttatctgatggaaaggaatatttttgacgttttttctgaaatgaag gatcatgaaatgtttgcgaaagagctgttttatgcatcgttggcaaggattttgaaacgt ctccaagagcaccaaaaaccgagtcaagattctgaagacgtttcattttatgagtcatct ttccaaattttcgatgaagtcctcaagaaaatgtggccatatctttcgaaaacagattcg agcatcaagaaaaacagtatgaaaatattcgaaaaacttctaagtatttgtccaaacaac gtgcttgttcaaaaattgacagaaaaatttgtggatacgtgtggatggctaaaaatttct gcagaagatatttgtgaagaaatggagccaagattgtggaaagttgttgggtcacttgtg gcacgacttcttgatttgaagaaaacgattccatatgaaattgtttcgtacgcaatcgct gttcatataacacaagaagtgacgctagccagtccagaggattatgctccagacgatttt gaggcactttgcgaacaaccaccaggtggaagtaagaaggaaatgtttttgagatcaatg gttgatgcgacccgtgcctcacttctccaagtgctcatttatctcagaacttccaaaagt agttcagatgttgttcagtttatgagagactactattcagagctggttttcagtcaagaa actctgattatgcatgcatcaattgacatgttcagagaatcaacatttcgggattcaatt aaatctgaagatattctatccatcgttgattctatcattgatacacctgcgattgtgtcg atggttctcgttatatgtggaatcaaagatgtaaaaacagcaaaacaggctcttgagaaa acattgattcgaatggccaacgatttggaagatgaagatcaaaaaagagaaggatatgtc aatcatttacacgaatctagctcattctgggcatgtgttgcgaagtatgcggataggaat attcttgataaagctgccaaacgatttgttgaagttgctattgacagtcccgatattcgg actgctacgctgtcggctgatatttttttgacaattttaaagttggaactagtttctgat gccgaaaagttgtcagaagatgctgtaatctgtaatgcgaagttctcaaattgggatatg gaagaatcgagattcagacaagtcggaaacaaactagtagagtgtaacatggcgaaacga ccgaaatatgcgcaagtgccccttttcacacttcaacatttacaagaagtcgatagtctt ccgatgagagatttgatctacactgtgactctgatgcaatttctgaaaacaaaagaagga atggagttgcataaacagttctatgaaaactatccgggactcgatgaaatcttcgaaaac tttcattcacgagaacacaagattcgattgtgttcgagacttctgggagagttcgccaaa attgtttcggaaaatgaaaaaggaagtctgattttcagtttggatcatgaaaatgttctg aactggttagaagaaattggtattatagattcgcctataatctctgagaaactgattgat ctcactttccatgttgaagtatggcatgctttgaactttctgcaattcgagagtaccgag tgtcatttcgacgatgttcaaacttttggacgaatctggatgacgaatgtgatggaagtt ataccagacaaaacactaagagaagttgaagatcaaataacaattatgttgaggaatcag tatgaaaagcagggttataaaatgaaggcgttacgagagaaacgattcaatggaaaattc ccaaaatatccgaaacctgaaccattggaaccacagatattgtcgatgcataatagaatt ggtatttggttaacgaagaagaaagtggaagagttcgctgatgaatctacaaagcttttc acgtggcttattggagtttgctctggacaaaagtcatatggggatgtggtcacggcggaa gcgaagaagattctggcaaagctctatccggatcaacaaaaacaagaagacattaaacat tattttggaatgtcagcactgttgaatggaattggaatatgcaaagaagaagagggaaaa ttctcattccgcccaatgtttattcgaatttatcaagaagttgtgtctagagatatgact acttgggaagctggttattcgatggaagtcatcagtaaacgattaggaggattccatgaa tggttggaagatgtgaatgaggaaaagttagagaaagacaatggtcatcatctccaagtg attcaaaagctatcccatcattgctggtttaaactcagaactattgaagtggctgaattg gacaatacgactccagaccatattcttcttactctcagaaagttttctgaagttatagca agtcgaatggacaagatcataaattggctcattcctacactcagtccattcactttagct tcacgactcgatctacttttagaaattattttcttattccctgaaatagtggaaaagtac aggaagcaaattgaatcgtatttcttcaaactattcgatttgttccttaaagaagaatac attgatggacttgtcaataatccagagttcaaaattcaaacaactgacaaatatctgtcg tccactttgaacacaaaaagggaatactatttgaaagatccgacccaaaataaactgttt cgagttccggatctgttgatgttgatcagcaaatatggatcaaagaatgttcaaatttat tgtttgaaaaaaatcggagaagcattggcaatccttcctggaaaaattctggagaatcag gaagttcttagaggaaataagaatattgaggagaactccgaaaaacgtgttgcctgtgat gtaatcgttctgtcagagttcctggggtacttcaactgtctttactctcaaatttcgatg gaaactctatctgaaccttctgaagaaaccataatgaagactttcatgctgctcgatact ggatctcgctcgaaaaatgagactaacaagaggaaaacgagtagcggtttgccacgtcat catcaggatcatatagacatgaagtactgtaccttcaagtcaactggaaacaagttcaca agccagcattggtacaactgttacacttgcaacatgatggaatctactggagtatgcagt acttgtgctgtcaactgtcatcgtggccatgagcttgcctactcgaaaaagggagcattt ttctgtgattgtggatcaaaaccgtgtgatgcaatgaaaggagccgatcattatccgaat gcgatgaactcgttaagaggacaatttccagataatagtattcagaaaacgtcaccaaag cctagagatgtttttgtgtacttcttcgaattcttgaaaacaaaagatgatgactttgaa gaattgaagaattcactgaaagcagttcagaaagaatttcaaaaagctcaaaacgacttg gagaaagttttggaatcgatcgattacgcaaatcgaaaggcattgaatgtcaccgaacat cagagatcagttgttgagtcgatgaagaatatggatagagttgtgttggaagagaaagag gaattcatgtcgcctctagatgcagcaggtcactttcttccaatacgtggatccgattca atggttcaagacaggggcttgagtataactctacgtcagcgagaactggcagacatcata aaattggatgatggaacagagctactcgtgatgataccagatagcgttcaatcgtgtctt caattacattatatggacacgaggactcatttgcttcaaggaatgcattgtcttcggact gaaactgagcaaattccatttagtcccgtcagtttggatgtgtccggaaatcgtttggtt gtttgcggaacctatgagatctatgcattgagattctctccgcaaggtactgttattgat agagcacacattaagctattggagaatggaagttctggctcgatgaatggaaatccggtg aagaaagcaagattttgtccggagattgaaggggacacgaggaaaaaacagttgattgca gtagccacaatgcaatacatccgggtctacgacctgactctccatgagaccaacttcgtg gaagaaatggttttgactactggaaatgttgaagacgtgctcattctgaatccggttaat gggaatattagagtattggttctctcgtcatctggatatctctatgagcataatatcagc gactgtactgctgataacaactcaattttcctgacaaatgttgttaatactcctggaatg gatatgaatggtgatggagtatctcttcactactcatcgaaattcaatctgctctttgta tcgctcgactctgccctctacgtagctcgtttacctgaaccaactggcaactcacaagcg ccaatctatgactggaaaccaatgaatatcaaatggccagtggaagtttggagagaagca tctggaatcattgcgtgtttatcaaaagaaataacagatcaagtcatgtatttccatccg actgttgataaaatcatgatccaaaaaactcaagtaaatcggccaattatgacatttttc atgatgacaagttccaaaaatcaatcgatttactctgttatgatattccctaatttgccg acatgtgaaatttgggaatcctcatgggaaaacgttcatgatttatggattgccgacgtg ccaagtgaacgtttcgcgattgaagttgtcgagcagaagacggttccaaaaccattggat aaagaagatttggtgttgctggctgaacaatgtgaaccgattggaactgttgaatggagt tgtcgagatattgaaatgttctatacgcatactgaattgaatcatcgtttgtcgatttcc gaatcaatgccgattactgtagttcagcagacacacttcacgttgactgcaagagttact aattcaagacaaatcgttcgtatgatccgtctcgaagtagaaggaccaacaggaccagag tatctcaaaatcggaaatactcgttacacagtgtctacccgaaatgcaaaagtttatgat ttgagactcacacgtgaagaatctcttactctcgatcatcggaacataactattgaagtg attccaaagaccaatcagaatactgtaaaacttaaatctctgaaattgtatggatgtgat cggaatgcaatggatgaaatccaaccaagattcgaacgtcaaccagtattaaatactcca aatcgtctggtttattccattctagaattcccaggagaagacgtccaatgggttgaaaaa gttgcagaatctcatctctccagaaaactgaatcacccatctgtttgctcaatctccaca aaatcaattttgaaatgtcatccgaaaatcgatgaaaaactgttccaaattatcgacaga tcgtatttacaagagtggaaatcacttgccaactggacagaagaatccggattctcagag atgagaatgcaccatgtggagcatttactggatagaatggaagcagttagaacaagatgg ccttatttctatcagaccctgaaacaagagttcggagcagtgacatgttttgtggaattg atgagagatgaaatgagaaagatgccacttcacagatgtcaaatgatggctcaagcgata gtgaaagttgtttttggaatgttgagttatggaactgatgaatcagagaaacttattcat gtcttcttggatatcttcacggataactccacctatcatttagctaacgaccttcgatca gcagttcaagagactttttcgagatatgataatgtattgaaacaagagaaacaattgatt gaaggaaaggacaaaaaagagctcatccgaatcggcaatactggtcttgctccgttctat ggtgctccgagagttcttgcaaagacgccagctaacttgatgatttcaaatgttaccgac actttgccgttggaggaaatagagaaaactacttggctagatcagataatatcgttactt ttagagaaactttcgagatcgaaatcaacatccacgtggcaaaacatctctgactctcca gcttacaatttgtcaagagtcttggccagttgtgttgcaatctgtgatccaaaaatcatt ggatcccacttctcgagactgattcgactgatcagttacgatgcgaatgagatttatccg ttcagtgaaaaaacattccccaactattctctgttaagatctgtggaacttcttcttttt gtatgtctcgaaaaacgaggagaggagaaaaaagagaatttggaaatgttggattcaatt gttaacgaactccaaactgtcggaattcgagatttatgtttcaacgttttggagaaagtg attcctgaatggaaggagagaggacctgccacgtttgcgagaaactcttctgaaagtcat cgaaaagtttggttgccacacgttccattggtttcatcgtctgcaaatccgccaaatgca aatgttatgaactggccatctagcctcgaagacgcttacattatagcttgcaccgatttg gttctcctaatcccacaacatcttcaagaattagaccgcagaaaatcagtaccacgtgac gatcgttggattcagaaattgtgtcaattggctaatttgagcaatggatgttcagcatat cgacaatgtaaaaagcttcttcttgcaatgtgttacaatgatgaaacgaaatacaaaata atgagagacaagtataaaatgcaagaacttcttcaacaattggttaataagtatttgaat gtgagtaaagaggttggaggacatcaacagttgactgaaatcgtggatattcttgcttca attacaaagctcgcaatgattcgaccagatatgtggagagatgtttgcagtacttatacc acttggctcctccgtctcgcttgttacacaacaaaagttgtcgcatcccaagttgtcgaa cttctcatagtcgctgtccgtgattcaagtgttggtgggcaactgagcattcagttggct gatagtatcattgaagctcaaaatggagaatttattgaaaagataatcaaaagattttta ataggaaaggacgaacaattgagatggacacttcatggcatgcttcgatctgttatccaa ttggcaagtcggcagaatcagtgttcgattgtcaagaaattgtacaacactgtatatcca atggtagagaatcttggagttcaaggtgctcagctggtcgatctcattgcaacgtacgcc cccagagtgttcagttctgcagagctggtatccatgactcaatctgaaatttcaacgatt caaaagatcggggacacgctggataaggatggatatcagggaatgtacgaactaatgagt catttgggtctcggatggaaatcaattcaattcgacagaaatccatgtcttgtttgcttc acaagtagaggaattcatgatgttgtgaagatgactacaatcaaatcagataccagatat tctgccaataccatgatctacaagctactctcaaattatgaaatttcaaaagtcattatc aaactgagtgatgtcaaaaagagtaaagccatcaggaaagtttccctctattactcagcc aaatccgttgaatctgtggaattgaaattacatcctgaattgtggagaaagtgtgcagta gtcaatgttggagaaaacgagacaataatcaacctctcgttggctgttccagtcgtaact tcctcattgattattgagttcgatgaagtcacggatcaacgtagttccagtcaacttcat tgtccccgttgctctggacctgttcgaactcattcgggagtgtgtgatagttgtggagag aatgcattccaatgcatgaagtgtcgatccataaattacgtggaaaaggaaccattctta tgtcaaagttgtgggtactgtaagtacgcgaggatcgagttatcggcagtgtgtcgggct cttcctggtgctcaacatatcacctgtgatgctgaaagaggacaatgtgtacaggaaatc acgcagttattgactaaaatggagactactaaaaccaaattaactggatacagagctgta tgcgagtctctctacctcaaaaaccgtcctctcccgccctacaaacttcacgtggaaaac aaccatgcatctgaattcttcgaaacgaacggaacaatgagcacagagcaattggcattc caatcggtcacgaatccaatgagtaatcttgcggttacaatcaaaactcttcacacagag ctatgtcaacaaactcaacagctgatgtacttacacgaggaattgaatcgatatgatcat gcatcagaagtatcaattgtgttccataaatcacagaacacttcttactattcaacaagt gaatcatgtttcggatgtctctgtaatcaacttctccattcgatcgcccttcttcattct gcttgtgacgatgaaaatgcactgaatctccttctttcattcgattcaacaatcgagaga cttggaatattagctcaaacttatgagacacttcgagaagaagttgaagaactgctagtt cgtttgatgtttggaagaactgatgtcacctcgaaaattgagaaattgattgaaaatgga gatgtcaacttgtcggtgatggtcaaatccttgatgtatgcagctgatccaacatggcaa caaaaactgaaattattagttcgatttgcaattgagaagagagatgagaacagttgtctt caagctttgatggttttgaataaatatttggaagcgacgaaaacagtttcgatggatgag aggaagaagattaaagtgacgaagaaggaaggagtcgtcaaatggcttacttcagacgaa gattggaacgactgttgttcgatagcctcaacatctaccgctcctccaccctcaacaccg tcaaatccttacgaatggatttctgaatgtcttttctctcaatggatgtctgttcgatcg gcagcaaatcaattgttgataaatctatctcgtcaacaattccatgaaccaattgcttta cttcttctgtgtgagaatttagcgaaactgacgactcttccttcggcagactgcgatcag ttcatgagttcatgtcatacgataattgattcgtccgtcaatacgaaaacaagattattt gtacaacagttccatgtgtacctcatcagaaaaattcatgaagaatgtgcaaatctacat ggacagaagatcacactttcaacggataatacatttggagagagattgagatgcttcgtt gaattactgtcgcttctcttatctggatcatatgtcgaaaacgttcttctgaaggctgga gctgatgatttattgattttcttgcttcattctaccatctttttgaaaagaatgatgact agaaggacgcgtgcaatcgattcatctcggacggcattagagaaactattaaaaagagtt tcatgtcgagatggtacgaaactgatgagtgtatgtgtggattcgttgaagttggtgaaa gatacttccacattgggaatcattgttggcgtcatgatggaaatcatgaatccacaacag gaaactgaagagtcgttcctcattcagattgagaaagatgtggcacaagaagacttttta caaggaagaatgacacataacccgtataattcaaacgatcttggaatgggacctctgatg cgtgatatcaagaacaaaatctgccgagacactgaaatgatagcgttgatggaagatgat aatggaatggaattgcttgtaaatgggaacattatttcactctccttgagtgttcgagag gtttatgatcggttgtggaagagaacaaataacggttctcctatgctcattgtctaccgt atgcgtggattgatgggagatgctgtggaaacgttcattgagaattttggagtcgctgag aattcagaagaagacgatgaagaggatgagcagttggtccgaatgactaattgtttgaca caatgtggaggaattgataagttgatggatttgatggcgactaacgtggagtcaagctct ggaagatttcttctcggacaccttcggaagatgttcgaacgaattgtgaagattcctgtc ggccgaagagttttaattgaacgtcgaatggttgaaagaatgatgtcagtggttcgaacg tgttgtgcagatccaacaaatgaatcgaaagttgcaatcgggatggagttatataaagtt gttgaattcgtggtttccgataagcatgtccaggatatattatgtggaatcaaagaagaa gacgctaattggtggtttgacctgttcgagaaacgtggaaatgaagagggatcagtaaca gaattacatcgaaaaactgcacaaattctggatcaaatgacatcgagcatcggaaacata gtaatgggatcagatgcatctgaaaatgttctcgttggaatgtactccagaattctgaaa tgggatgttattgatgcaggtgtaccaccttcggatattcaagcacgtcaacgaatttca agaagagatcaaactattatgatgactgaacagctggcgaatattacagcaaacattctt ccatccacttatggagcaagattgaagcaaaagattctggattctggagttattgccacg acttgtcagtacttgatgaaagatcttccgaatctttatcagccaacagagtcacctgaa tggaaggttttcttgtcacagccatcgttgaagttaattttgactcttctcgctggactc gcacgtggacatcaagcttcgcagaaagagattgcaaagactactttgaagctgatgcac cgtctcgaacaagtggcatctgataattcaattggaacattggctgaaaacgtgatcgaa gctttgaatgaagatgaggaagtgaaaaatcaaatcaaaatggttcgagatgaaacggag aagaaaaagaagcagatggcaatgatgaatcgagagaaacaattgatgaaaatgagaatg aaagtgggaacaggaggacagattaaggtctcctcaagaacccttcacaatgaaccaagt atcgatgacaccgactcgctttcgtgttgtatctgtcgagaaagtgtgattcgtggaagt caggcatctggagtctacgcattcgccgctatcgatcaagagtcagcccgtacttgtaca gtttcaatgatggttatggtacacctggactgccataaaaatgcgattcgtggtggaggc ggcggacgggcggttgatgagtggacacgatcaaaattgcacaatgcaggtgccaagtgt aatgtgattactccgattgcaatgggaacgactactgatgagatatggatagaagcaatt catcgatacgagatcgatattggaagggtttctggattggctcatgtagttgttaacaga aatttcgttttcattgacatctgtaaattggttaatcgattcattcataagagatccttc tcccttcaatcagaaggcggtggtcgcgaatctaacatgcaataccttgccattcttcat cttttcggtgtttctcttccagctgatgctgcagaattggaaatctcctcttccgatcaa cgtctcattggattcctcttcacagagctgaccactgagagttggaatgatcagaagaac gacgtactgcgtgcaactctacacgatgctcagacaaatggaccgattgccacgtatcaa gatgcgaaacccattcttatgacgtgggcgttcgtggatgcgtatttcaataaagttatc aagatcaccggagatgatcgtttggaatggctccgtgagcatcttgtcgaaactatcaat aagacacgtggatttgttgatgacttcgattcgaacgttcttccatgtgagggactagca gagttctgcgacgtcaccggtgcgctactcaatgagttagctgtattccttccggataac taa

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