Chlorocebus sabaeus (green monkey): 103224682 Help Entry 103224682         CDS       T04361                                  Symbol JAK1 Name (RefSeq) Janus kinase 1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism csab  Chlorocebus sabaeus (green monkey) Pathway csab01521   EGFR tyrosine kinase inhibitor resistance csab04151   PI3K-Akt signaling pathway csab04217   Necroptosis csab04380   Osteoclast differentiation csab04550   Signaling pathways regulating pluripotency of stem cells csab04620   Toll-like receptor signaling pathway csab04621   NOD-like receptor signaling pathway csab04630   JAK-STAT signaling pathway csab04658   Th1 and Th2 cell differentiation csab04659   Th17 cell differentiation csab05140   Leishmaniasis csab05145   Toxoplasmosis csab05152   Tuberculosis csab05160   Hepatitis C csab05161   Hepatitis B csab05162   Measles csab05163   Human cytomegalovirus infection csab05164   Influenza A csab05165   Human papillomavirus infection csab05166   Human T-cell leukemia virus 1 infection csab05167   Kaposi sarcoma-associated herpesvirus infection csab05168   Herpes simplex virus 1 infection csab05169   Epstein-Barr virus infection csab05171   Coronavirus disease - COVID-19 csab05200   Pathways in cancer csab05203   Viral carcinogenesis csab05212   Pancreatic cancer csab05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:csab00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     103224682 (JAK1)    04151 PI3K-Akt signaling pathway     103224682 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     103224682 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     103224682 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     103224682 (JAK1)    04621 NOD-like receptor signaling pathway     103224682 (JAK1)    04658 Th1 and Th2 cell differentiation     103224682 (JAK1)    04659 Th17 cell differentiation     103224682 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     103224682 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103224682 (JAK1)    05203 Viral carcinogenesis     103224682 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     103224682 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     103224682 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103224682 (JAK1)    05161 Hepatitis B     103224682 (JAK1)    05160 Hepatitis C     103224682 (JAK1)    05171 Coronavirus disease - COVID-19     103224682 (JAK1)    05164 Influenza A     103224682 (JAK1)    05162 Measles     103224682 (JAK1)    05168 Herpes simplex virus 1 infection     103224682 (JAK1)    05163 Human cytomegalovirus infection     103224682 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     103224682 (JAK1)    05169 Epstein-Barr virus infection     103224682 (JAK1)    05165 Human papillomavirus infection     103224682 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     103224682 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     103224682 (JAK1)    05140 Leishmaniasis     103224682 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103224682 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:csab01001]     103224682 (JAK1) Enzymes [BR:csab01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      103224682 (JAK1) Protein kinases [BR:csab01001]  Non-receptor tyrosine kinases   JAK family [OT]    103224682 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  103224682 NCBI-ProteinID:  XP_007976644 Ensembl:  ENSCSAG00000001351 UniProt:  A0A0D9S727 LinkDB All DBs Position 20:68122134..68253361 Genome browser AA seq 1154 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEVPEPGVEVIFYMSDREPLRLGSGEYTAEEL CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHSNDSGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLESKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEQGQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRIFKKDLVQGEHLGRGTRTHIYSG TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT SFQNLIEGFEALLK NT seq 3465 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgaggtgaacctggaggtccctgagccaggggtggaagtgatcttc tatatgtcggacagggagcccctccggctgggcagtggagagtatacagcagaggaactg tgcatcagggctgcacaggcatgccgtatctctcctctttgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccaaatcgcaccatcaccgttgatgacaag atgtccctccgactccactaccggatgaggttctatttcaccaattggcatggaaccaac gacaatgagcagtcagtgtggcgtcattctccaaagaagcagaaaaatggctacgagaaa aaaaaggttccagatgcaacccctctccttgatgccagctcactggagtatctgtttgct cagggacagtatgatttggtgaaatgcctggctcccattcgagaccccaagaccgagcag gatgggcatgatattgaaaacgagtgtctggggatggctgtcctggccatctcacactat gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagc gtgtccacgcatgacctaaaggtgaaatacttggctaccttggaaactttgacaaaacat tatggcgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat tggtttcattcaaatgacagtggaaacgttctgtactatgaagtgatggtgactgggaat cttggaatccagtggaggcataaaccaaatgttgtttctgttgaaaaggaaaaaaataaa ctgaagcggaaaaaactggaaagtaaacacaagaaggatgaggagaaaaacaagatccgg gaagagtggaacaatttttcttacttccctgaaatcactcacattgtaataaaggaatct gtggtcagcattaacaagcaggacaacaagaaaatggaactgaagctctcttcccatgag gaggccttgtcctttgtgtcactggtagatggctacttccggctcaccgcagacgcccat cattacctctgcaccgacgtggcccccccgttgatcgtccacaacatacagaatggctgt catggtccaatctgtacagaatacgccatcaataaattgcggcaagaaggaagcgaggag gggatgtacgtgctgaggtggagctgcaccgactttgacaacatcctcatgaccgtcacc tgctttgagaagtctgagcaggggcagggtgcccagaagcagttcaagaactttcagatc gaggtgcagaagggccgctacagcctgcatggttcggatcgcagcttccccagcttggga gacctcatgagccacctcaagaagcagatcctgcgcacggataacatcagcttcatgttg aaacgctgctgccagcccaagccccgagaaatctccaacctgctggtggctactaagaaa gcccaggagtggcagcccgtctaccccatgagccagctgagttttgatcggatcttcaag aaggatctggtgcagggcgagcaccttgggagaggcacgagaacacacatctactctggg accctgatggattacaaggatgacgaaggaacttctgaagagaagaagataaaagtgatc ctcaaagtcttagaccccagccacagggatatttccctggccttcttcgaggcagccagc atgatgagacaggtctcccacaaacacatcgtatacctctatggcgtctgtgtccgtgac gtggagaatatcatggtggaagagtttgtggaagggggtcctctggatctcttcatgcac cggaaaagcgatgtccttactacaccctggaaattcaaagttgccaaacagctggccagt gccctgagctacttggaagataaagacctggtccatggaaatgtgtgtactaaaaacctc ctcctggcccgtgagggcatcgacagcgagtgtggtccgttcatcaagctcagtgaccct ggcatccccattacggtgctgtctaggcaagagtgcattgaacgaatcccgtggattgct cccgagtgtgttgaggactccaagaacctgagtgtggctgctgacaagtggagctttgga actacgctctgggaaatctgctacaatggcgagatccccttgaaagacaagacactgatt gagaaagagagattctatgaaagccggtgcaggccagtgacaccatcatgtaaggagctg gctgacctcatgacccgctgcatgaactacgaccccaatcagaggcccttcttccgagcc atcatgagagacattaataagcttgaagagcagaatccagatattgtttcagaaaaaaag ccagcaactgaagtggaccccacgcattttgaaaagcgcttcctaaagaggatccgtgac ttgggagagggccactttgggaaggttgagctctgcaggtatgaccccgaaggggacaat acaggggagcaggtggctgtcaaatctctgaagcctgagagtggaggtaaccacatagct gatctgaaaaaggaaatcgagatcttaaggaacctctatcatgagaacattgtgaagtac aaaggaatctgcacagaagacggaggaaatggtattaagctcatcatggaatttctgcct tcgggaagccttaaggagtatcttccaaagaataagaacaaaattaacctcaaacagcag ctaaaatatgccgttcagatttgtaaggggatggactatttgggttctcggcaatatgtt caccgtgacttggcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattgga gacttcggtttaaccaaagcaattgaaaccgataaggagtattacaccgtcaaggatgac cgggacagccctgtgttttggtatgctccagaatgtttaatgcagtctaaattttatatc gcctctgacgtctggtcttttggagtcactctgcatgagctgctgacttactgtgattca gattctagtcccatggctttgttcctgaaaatgataggcccaacccatggccagatgaca gtcacaagacttgtgaatacattaaaagaaggaaaacgcctgccgtgcccgcctaactgt ccagatgaggtttatcaacttatgaggaaatgctgggaattccaaccatccaatcggaca agctttcagaaccttattgaaggatttgaagcacttttaaaataa

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