Chlorocebus sabaeus (green monkey): 103228031
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Entry
103228031 CDS
T04361
Symbol
RAF1
Name
(RefSeq) Raf-1 proto-oncogene, serine/threonine kinase
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
csab
Chlorocebus sabaeus (green monkey)
Pathway
csab01521
EGFR tyrosine kinase inhibitor resistance
csab01522
Endocrine resistance
csab04010
MAPK signaling pathway
csab04012
ErbB signaling pathway
csab04014
Ras signaling pathway
csab04015
Rap1 signaling pathway
csab04022
cGMP-PKG signaling pathway
csab04024
cAMP signaling pathway
csab04062
Chemokine signaling pathway
csab04068
FoxO signaling pathway
csab04071
Sphingolipid signaling pathway
csab04072
Phospholipase D signaling pathway
csab04140
Autophagy - animal
csab04150
mTOR signaling pathway
csab04151
PI3K-Akt signaling pathway
csab04210
Apoptosis
csab04218
Cellular senescence
csab04270
Vascular smooth muscle contraction
csab04360
Axon guidance
csab04370
VEGF signaling pathway
csab04371
Apelin signaling pathway
csab04510
Focal adhesion
csab04540
Gap junction
csab04550
Signaling pathways regulating pluripotency of stem cells
csab04613
Neutrophil extracellular trap formation
csab04625
C-type lectin receptor signaling pathway
csab04630
JAK-STAT signaling pathway
csab04650
Natural killer cell mediated cytotoxicity
csab04660
T cell receptor signaling pathway
csab04662
B cell receptor signaling pathway
csab04664
Fc epsilon RI signaling pathway
csab04666
Fc gamma R-mediated phagocytosis
csab04720
Long-term potentiation
csab04722
Neurotrophin signaling pathway
csab04726
Serotonergic synapse
csab04730
Long-term depression
csab04810
Regulation of actin cytoskeleton
csab04910
Insulin signaling pathway
csab04912
GnRH signaling pathway
csab04914
Progesterone-mediated oocyte maturation
csab04915
Estrogen signaling pathway
csab04916
Melanogenesis
csab04917
Prolactin signaling pathway
csab04919
Thyroid hormone signaling pathway
csab04921
Oxytocin signaling pathway
csab04926
Relaxin signaling pathway
csab04928
Parathyroid hormone synthesis, secretion and action
csab04929
GnRH secretion
csab04935
Growth hormone synthesis, secretion and action
csab05010
Alzheimer disease
csab05022
Pathways of neurodegeneration - multiple diseases
csab05034
Alcoholism
csab05132
Salmonella infection
csab05152
Tuberculosis
csab05160
Hepatitis C
csab05161
Hepatitis B
csab05163
Human cytomegalovirus infection
csab05164
Influenza A
csab05165
Human papillomavirus infection
csab05167
Kaposi sarcoma-associated herpesvirus infection
csab05170
Human immunodeficiency virus 1 infection
csab05200
Pathways in cancer
csab05205
Proteoglycans in cancer
csab05206
MicroRNAs in cancer
csab05207
Chemical carcinogenesis - receptor activation
csab05208
Chemical carcinogenesis - reactive oxygen species
csab05210
Colorectal cancer
csab05211
Renal cell carcinoma
csab05212
Pancreatic cancer
csab05213
Endometrial cancer
csab05214
Glioma
csab05215
Prostate cancer
csab05218
Melanoma
csab05219
Bladder cancer
csab05220
Chronic myeloid leukemia
csab05221
Acute myeloid leukemia
csab05223
Non-small cell lung cancer
csab05224
Breast cancer
csab05225
Hepatocellular carcinoma
csab05226
Gastric cancer
csab05230
Central carbon metabolism in cancer
csab05231
Choline metabolism in cancer
csab05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
csab00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103228031 (RAF1)
04012 ErbB signaling pathway
103228031 (RAF1)
04014 Ras signaling pathway
103228031 (RAF1)
04015 Rap1 signaling pathway
103228031 (RAF1)
04370 VEGF signaling pathway
103228031 (RAF1)
04371 Apelin signaling pathway
103228031 (RAF1)
04630 JAK-STAT signaling pathway
103228031 (RAF1)
04068 FoxO signaling pathway
103228031 (RAF1)
04072 Phospholipase D signaling pathway
103228031 (RAF1)
04071 Sphingolipid signaling pathway
103228031 (RAF1)
04024 cAMP signaling pathway
103228031 (RAF1)
04022 cGMP-PKG signaling pathway
103228031 (RAF1)
04151 PI3K-Akt signaling pathway
103228031 (RAF1)
04150 mTOR signaling pathway
103228031 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103228031 (RAF1)
09143 Cell growth and death
04210 Apoptosis
103228031 (RAF1)
04218 Cellular senescence
103228031 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103228031 (RAF1)
04540 Gap junction
103228031 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
103228031 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103228031 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
103228031 (RAF1)
04625 C-type lectin receptor signaling pathway
103228031 (RAF1)
04650 Natural killer cell mediated cytotoxicity
103228031 (RAF1)
04660 T cell receptor signaling pathway
103228031 (RAF1)
04662 B cell receptor signaling pathway
103228031 (RAF1)
04664 Fc epsilon RI signaling pathway
103228031 (RAF1)
04666 Fc gamma R-mediated phagocytosis
103228031 (RAF1)
04062 Chemokine signaling pathway
103228031 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
103228031 (RAF1)
04929 GnRH secretion
103228031 (RAF1)
04912 GnRH signaling pathway
103228031 (RAF1)
04915 Estrogen signaling pathway
103228031 (RAF1)
04914 Progesterone-mediated oocyte maturation
103228031 (RAF1)
04917 Prolactin signaling pathway
103228031 (RAF1)
04921 Oxytocin signaling pathway
103228031 (RAF1)
04926 Relaxin signaling pathway
103228031 (RAF1)
04935 Growth hormone synthesis, secretion and action
103228031 (RAF1)
04919 Thyroid hormone signaling pathway
103228031 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
103228031 (RAF1)
04916 Melanogenesis
103228031 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
103228031 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
103228031 (RAF1)
04720 Long-term potentiation
103228031 (RAF1)
04730 Long-term depression
103228031 (RAF1)
04722 Neurotrophin signaling pathway
103228031 (RAF1)
09158 Development and regeneration
04360 Axon guidance
103228031 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103228031 (RAF1)
05206 MicroRNAs in cancer
103228031 (RAF1)
05205 Proteoglycans in cancer
103228031 (RAF1)
05207 Chemical carcinogenesis - receptor activation
103228031 (RAF1)
05208 Chemical carcinogenesis - reactive oxygen species
103228031 (RAF1)
05230 Central carbon metabolism in cancer
103228031 (RAF1)
05231 Choline metabolism in cancer
103228031 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103228031 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
103228031 (RAF1)
05212 Pancreatic cancer
103228031 (RAF1)
05225 Hepatocellular carcinoma
103228031 (RAF1)
05226 Gastric cancer
103228031 (RAF1)
05214 Glioma
103228031 (RAF1)
05221 Acute myeloid leukemia
103228031 (RAF1)
05220 Chronic myeloid leukemia
103228031 (RAF1)
05218 Melanoma
103228031 (RAF1)
05211 Renal cell carcinoma
103228031 (RAF1)
05219 Bladder cancer
103228031 (RAF1)
05215 Prostate cancer
103228031 (RAF1)
05213 Endometrial cancer
103228031 (RAF1)
05224 Breast cancer
103228031 (RAF1)
05223 Non-small cell lung cancer
103228031 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
103228031 (RAF1)
05161 Hepatitis B
103228031 (RAF1)
05160 Hepatitis C
103228031 (RAF1)
05164 Influenza A
103228031 (RAF1)
05163 Human cytomegalovirus infection
103228031 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
103228031 (RAF1)
05165 Human papillomavirus infection
103228031 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
103228031 (RAF1)
05152 Tuberculosis
103228031 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
103228031 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
103228031 (RAF1)
09165 Substance dependence
05034 Alcoholism
103228031 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103228031 (RAF1)
01522 Endocrine resistance
103228031 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
csab01001
]
103228031 (RAF1)
Enzymes [BR:
csab01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103228031 (RAF1)
Protein kinases [BR:
csab01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
103228031 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RBD
C1_1
Kinase-like
ABC1
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
103228031
NCBI-ProteinID:
XP_007983458
Ensembl:
ENSCSAG00000009721
UniProt:
A0A0D9RB89
LinkDB
All DBs
Position
22:complement(48560270..48643537)
Genome browser
AA seq
648 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNL
SPTGWSQPKTPVPAQRERAAVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggagcttggaagacgatcagcaatggttttggattcaaagatgcc
gtgtttgatggctccagctgcatctctcctacaatagttcagcagtttggctatcagcgc
cgggcatcagatgatggcaaactcacagatccttctaagacaagcaacactatccgtgtt
ttcttgccaaacaagcaaagaacagtggtcaatgtgcgaaatggaatgagcttgcatgac
tgccttatgaaagcactcaaggtgaggggccttcaaccagagtgctgtgcagtgttcaga
cttctccacgaacacaaaggtaaaaaagcacgcttagattggaatactgatgctgcctct
ttgattggggaagaacttcaagtagatttcctggatcatgttccactcacaacacacaac
tttgctcggaagacgttcctgaagcttgccttctgtgacatctgtcagaaattcctgctc
aatggatttcgatgtcagacttgtggctacaaatttcatgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttattgtttccaaattccact
attggtgatagtggagtcccagcactaccttctttgactatgcgtcgtatgcgagagtct
gtttccaggatgcctgttagttctcagcacaggtattctacacctcacgccttcaccttt
aacacctccagtccctcatctgaaggttccctctcccagaggcagaggtcgacgtccaca
cctaacgtccacatggtcagcaccaccctgcctgtggacagcaggatgattgaggatgca
attcgaagtcacagcgaatcagcctcaccttcagccctgtccagtagccccaacaatctg
agcccaacaggctggtcacagccgaaaacacccgtgccagcacaaagagagcgggcagca
gtatctgggacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagtgaagtgatgctgtccactcggattgggtcaggctctttt
ggaactgtttataagggcaaatggcatggagatgttgcagtaaagatcctaaaggttgtt
gacccaaccccagagcaattccaggccttcaggaatgaggtggctgttctgcgcaaaaca
cggcatgtgaacattctgcttttcatggggtatatgacaaaggacaacctggcaattgtg
acccagtggtgcgagggcagcagcctctacaaacacctgcatgtccaggagaccaagttt
cagatgttccagctaattgacattgcccggcagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggccta
acagtgaaaattggagattttggtttggcaacagtaaagtcacgctggagtggttctcag
caggttgaacaacctactggctctgtcctgtggatggccccagaggtgatccgaatgcag
gataacaacccattcagtttccagtcggatgtctactcctatggcatcgtattgtatgag
ctgatgacgggggaacttccttactctcacatcaacaaccgagatcagatcatcttcatg
gtgggccgagggtatgcctccccagatcttagtaagctatataagaactgccccaaagca
atgaagaggctggtagctgactgtgtgaagaaagtaaaggaagagaggcctctttttccc
cagatcctgtcttccattgagctgctccaacactctctaccgaagatcaaccggagcgct
tccgagccatccttgcatcgggcagcccacactgaggatatcaatgcttgcacgctgacc
acgtccccgaggctgcctgtcttctag
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