| Entry |
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| Symbol |
NLRP3
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| Name |
(RefSeq) NLR family pyrin domain containing 3
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| KO |
| K12800 | NACHT, LRR and PYD domains-containing protein 3 |
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| Organism |
csab Chlorocebus sabaeus (green monkey)
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| Pathway |
| csab04621 | NOD-like receptor signaling pathway |
| csab04625 | C-type lectin receptor signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:csab00001]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
103230928 (NLRP3)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
103230928 (NLRP3)
04623 Cytosolic DNA-sensing pathway
103230928 (NLRP3)
04625 C-type lectin receptor signaling pathway
103230928 (NLRP3)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
103230928 (NLRP3)
05164 Influenza A
103230928 (NLRP3)
09171 Infectious disease: bacterial
05132 Salmonella infection
103230928 (NLRP3)
05135 Yersinia infection
103230928 (NLRP3)
05133 Pertussis
103230928 (NLRP3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103230928 (NLRP3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:csab04131]
103230928 (NLRP3)
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors [BR:csab04054]
103230928 (NLRP3)
Membrane trafficking [BR:csab04131]
Autophagy
Other autophagy associated proteins
TRIM-directed selective autophagy
103230928 (NLRP3)
Pattern recognition receptors [BR:csab04054]
Cytoplasmic pattern recognition receptors
NOD-like receptors
103230928 (NLRP3)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
25:84431436..84463387
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| AA seq |
1035 aa
MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCISLPRGQTEKADHVDLATLMID
FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTMICQEDSIEEEWMGL
LEYLSRISICKKKKDYCKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
QEREHELLAIGKTKTWESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKIM
LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIRKIVSKPSRILFL
MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
GLKQQMESGKSLAQTSKTTTAVYTFFLSSLLQPRGGSQEHRLCAPLWGLCSLAADGIWNQ
KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
EGRTNVPGSCLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTCYLEKKLSCKI
SQQIRLELLKWIEEKAKAKKLQTQPSQLELFYCLYEMQEEDFVRRAMDYFPKIEINLSTR
MDHVVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPGSHAACSHRLV
NSDLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPDCNIRRLWLGRCG
LSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTS
ACCQDLASVLSASRSLTRLYVGENALGDAGVAILCEKAKNPQCNLQKLGLVNSGLTSVCC
SALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDL
STLLTSSQSLQKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETL
QEEKPGLTIIFEPSW |
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| NT seq |
3108 nt +upstreamnt +downstreamnt
atgaagatggcaagcacccgctgcaagctggccaggtacctggaggacctggaggatgtg
gacttgaagaaatttaagatgcacttagaggactatcctcctcagaagggctgcatctcc
ctcccgaggggtcagacggagaaggcagaccatgtggatctagccacgctaatgattgac
ttcaatggggaggagaaggcgtgggccatggccgtgtggatctttgctgcgatcaacagg
agagacctttatgagaaagcaaaaagagatgagccgaagtggggttcagataatgcacgt
gtttctaatcccaccatgatatgccaggaagacagcattgaagaggagtggatgggttta
ctggagtacctttcgagaatctctatttgtaaaaagaagaaagattactgtaagaagtac
agaaagtacgtgagaagcagattccagtgcattgaagacaggaatgcccgtctgggtgaa
agtgtgagcctcaacaaacgctacacacgactgcgcctcatcaaggagcaccggagccag
caggagagggagcacgagcttctggccatcggcaagaccaagacgtgggagagccccgtg
agtcccattaagatggagttgctgtttgaccccgatgatgagcactctgagcctgtgcac
accgtggtgttccagggagcggcagggattgggaaaacaatcctggccaggaagattatg
ttggactgggcgtcgggaacactctaccaagacaggtttgactatctgttctatatccac
tgtcgggaggtgagccttgtgacacagaggagcctgggggacctgatcatgagctgctgc
cctgacccaaacccacccattcgcaagatcgtgagcaagccctccagaatcctcttcctc
atggacggctttgacgagcttcaaggtgcctttgacgagcacataggaccgctctgcact
gactggcagaaggccgagcggggagacattctcctgagcagcctcatcagaaagaagctc
cttcctgaggcctctctgctcatcaccacgagacctgtggccctggagaaactgcagcac
ttgctggaccatcctcggcatgtggagatcctgggtttctccgaggccaaaaggaaagaa
tacttcttcaagtacttctctgatgaggcccaagccagggcagccttcagtctgattcag
gagaatgaggtcctcttcaccatgtgcttcatccccctggtctgctggatcgtgtgcact
ggactgaaacagcagatggagagtggcaagagccttgcccagacatccaagaccaccact
gcggtgtataccttcttcctttccagtttgctgcagccccggggagggagccaggagcac
cgcctctgtgcccccctctgggggctctgctctttggctgcagacggaatctggaaccag
aaaatcctatttgaggagtctgacctcaggaatcatgggctgcagaaggcggatgtgtct
gctttcctgaggatgaacctgttccagaaggaagtggactgtgagaagttctacagcttc
atccacatgactttccaggagttctttgccgccatgtactacctgctggaagaggaaaag
gaaggaaggaccaacgttccagggagttgtttgaagcttcccagccgagacgtgacagtc
cttctggaaaactatggcaaattcgaaaaggggtatttgatttttgttgtacgtttcctc
tttggcctggtaaaccaggagaggacctgctacttggagaagaaattaagttgcaagatc
tctcagcaaatcaggctggagctgttgaaatggattgaagagaaagccaaagccaagaag
ctgcagacccagcccagccagctggaattgttctactgtttgtacgagatgcaggaggag
gacttcgtgcgaagggccatggactacttccccaagattgagatcaatctctccaccaga
atggatcacgtggtttcttccttttgcattgagaactgtcatcgggtggagtcactttcc
ctggggtttctccataacatgcccaaggaggaagaggaggaggaaaaggaaggccgacac
cttgatatggtacagtgtgtcctcccgggctctcatgctgcctgttcccacagattggtg
aacagcgatctcacttccagtttttgccggggcctcttttcagttctcagcaccagccag
agtctaactgaattggacctcagtgacaattctctgggggacccagggatgagagtattg
tgtgaaacgctccagcatcctgactgtaacattcggagattgtggttggggcgctgcggc
ctctcgcatgagtgctgcttcgacatctccttggtcctcagcagcaaccagaagctggtg
gagctggacctgagcgacaacgcccttggggacttcgggatcagacttctgtgtgtggga
ctgaagcacctgttgtgcaatctgaagaagctctggctggtcagctgctgcctcacatca
gcgtgttgtcaggatcttgcgtcagtattgagcgccagccgttccctgaccagactctac
gtgggggagaatgccctgggagacgcaggagtcgcaattttatgcgaaaaagccaagaat
ccacaatgtaacctgcagaaactggggttggtgaattctggccttacatcagtctgttgt
tcagctttgtcctcggtactcagcactaatcagaatctcacgcacctttacctgcgaggc
aacactcttggagacaaggggatcaagcttctctgtgagggactcttgcaccccgactgc
aagcttcaggtgttggaattagacaactgcaaccttacgtcacactgctgctgggatctt
tccacacttctgacctccagccagagcctgcaaaagctgagcctaggcaacaatgacctg
ggcgacctgggggtcatgatgttctgtgaagtgctgaaacagcagagctgcctcctgcag
aacctggggttgtctgaaatgtatttcaattatgagacaaaaagtgcgttagaaacactt
caagaagaaaagccggggctgaccatcatctttgagccttcgtggtag |
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