Chlorocebus sabaeus (green monkey): 103233371 Help Entry 103233371         CDS       T04361                                  Symbol PLCG2 Name (RefSeq) phospholipase C gamma 2   KO K05859   phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11] Organism csab  Chlorocebus sabaeus (green monkey) Pathway csab00562   Inositol phosphate metabolism csab01100   Metabolic pathways csab01521   EGFR tyrosine kinase inhibitor resistance csab04012   ErbB signaling pathway csab04014   Ras signaling pathway csab04020   Calcium signaling pathway csab04062   Chemokine signaling pathway csab04064   NF-kappa B signaling pathway csab04066   HIF-1 signaling pathway csab04070   Phosphatidylinositol signaling system csab04072   Phospholipase D signaling pathway csab04360   Axon guidance csab04370   VEGF signaling pathway csab04380   Osteoclast differentiation csab04517   IgSF CAM signaling csab04611   Platelet activation csab04613   Neutrophil extracellular trap formation csab04625   C-type lectin receptor signaling pathway csab04650   Natural killer cell mediated cytotoxicity csab04662   B cell receptor signaling pathway csab04664   Fc epsilon RI signaling pathway csab04666   Fc gamma R-mediated phagocytosis csab04670   Leukocyte transendothelial migration csab04722   Neurotrophin signaling pathway csab04750   Inflammatory mediator regulation of TRP channels csab04919   Thyroid hormone signaling pathway csab04933   AGE-RAGE signaling pathway in diabetic complications csab04935   Growth hormone synthesis, secretion and action csab05167   Kaposi sarcoma-associated herpesvirus infection csab05169   Epstein-Barr virus infection csab05170   Human immunodeficiency virus 1 infection csab05171   Coronavirus disease - COVID-19 csab05200   Pathways in cancer csab05205   Proteoglycans in cancer csab05206   MicroRNAs in cancer csab05214   Glioma csab05223   Non-small cell lung cancer csab05225   Hepatocellular carcinoma Module csab_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:csab00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     103233371 (PLCG2)  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     103233371 (PLCG2)    04014 Ras signaling pathway     103233371 (PLCG2)    04370 VEGF signaling pathway     103233371 (PLCG2)    04064 NF-kappa B signaling pathway     103233371 (PLCG2)    04066 HIF-1 signaling pathway     103233371 (PLCG2)    04020 Calcium signaling pathway     103233371 (PLCG2)    04070 Phosphatidylinositol signaling system     103233371 (PLCG2)    04072 Phospholipase D signaling pathway     103233371 (PLCG2)   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     103233371 (PLCG2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103233371 (PLCG2)    04613 Neutrophil extracellular trap formation     103233371 (PLCG2)    04625 C-type lectin receptor signaling pathway     103233371 (PLCG2)    04650 Natural killer cell mediated cytotoxicity     103233371 (PLCG2)    04662 B cell receptor signaling pathway     103233371 (PLCG2)    04664 Fc epsilon RI signaling pathway     103233371 (PLCG2)    04666 Fc gamma R-mediated phagocytosis     103233371 (PLCG2)    04670 Leukocyte transendothelial migration     103233371 (PLCG2)    04062 Chemokine signaling pathway     103233371 (PLCG2)   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     103233371 (PLCG2)    04919 Thyroid hormone signaling pathway     103233371 (PLCG2)   09156 Nervous system    04722 Neurotrophin signaling pathway     103233371 (PLCG2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103233371 (PLCG2)   09158 Development and regeneration    04360 Axon guidance     103233371 (PLCG2)    04380 Osteoclast differentiation     103233371 (PLCG2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103233371 (PLCG2)    05206 MicroRNAs in cancer     103233371 (PLCG2)    05205 Proteoglycans in cancer     103233371 (PLCG2)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     103233371 (PLCG2)    05214 Glioma     103233371 (PLCG2)    05223 Non-small cell lung cancer     103233371 (PLCG2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     103233371 (PLCG2)    05171 Coronavirus disease - COVID-19     103233371 (PLCG2)    05167 Kaposi sarcoma-associated herpesvirus infection     103233371 (PLCG2)    05169 Epstein-Barr virus infection     103233371 (PLCG2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     103233371 (PLCG2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103233371 (PLCG2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:csab04131]     103233371 (PLCG2) Enzymes [BR:csab01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      103233371 (PLCG2) Membrane trafficking [BR:csab04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     103233371 (PLCG2)  Endocytosis   Macropinocytosis    Phospholipase C     103233371 (PLCG2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI-PLC-X SH2 PI-PLC-Y EF_HAND_2_PLCG C2 SH3_1 SH3_9 PH PH_12 EF_HAND_1_PLCG SH2_1 SH3_2 PH_14 EF-hand_like Motif Other DBs NCBI-GeneID:  103233371 NCBI-ProteinID:  XP_007992373 Ensembl:  ENSCSAG00000003427 UniProt:  A0A0D9S186 LinkDB All DBs Position 5:67209268..67394865 Genome browser AA seq 1265 aa AA seqDB search MSTMVNVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGTQFVLNTLSLAADSKEDAL NWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSA KFLKDKFVEIGAHRDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA IYLHDFQRFLIHEQQEHWAQDLSKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS IWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDC WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKEHAFVTSSFPVILSIEEHCSVEQQRHMAKT FKEVFGDLLLMKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKQQGE LYMWDSIDQKWTRHYCAVADAKLSFSDDIEQTTEEEVPQDIPPTELHFGEKWFHKKVEKR TSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTTEGGTLKYY LTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYESLSRGEAEDML MRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY EKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY KAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADVEELEKQII EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF QSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE TKADSITRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKF MQMNHALFSLNGRTGYVLQPESMRAEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI ACPFVEVEICGADYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEED MFSDPNFLAHATYPIKAIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNKRLREKRVSN SKFYS NT seq 3798 nt NT seq  +upstreamnt  +downstreamnt atgtccaccatggtcaatgtggattcccttgcggaatatgagaagagccagatcaagaga gccctggagctggggacggtgatgactgtgttcagcttccgcaagtccacccctgagcgg aggaccgtccaggtgatcatggagacacggcaggtggcctggagcaagaccgctgacaag atcgagggcttcttggatatcatggaaataaaagaaatccgcccagggaagaactccaaa gatttcgaacgtgcaaaagcggttcgccagaaagaagattgctgcttcaccatcctgtat ggcactcagttcgtcctcaacacactcagcttggcagctgactctaaagaggatgcactt aattggctctccggcttgaaaatcttacaccaagaagcgatgaatgcgtccacacccacc attatcgagagttggctgagaaagcagatatattctgtggatcaaactagaagaaacagc atcagtctccgagagctgaagaccatcttgcccctgatcaactttaaagtgagcagtgcc aagttccttaaagataagtttgtggaaataggagcacacagagatgagctcagctttgaa cagttccatctcttctataaaaaacttatgttcgagcagcaaaaatcgattctcgatgaa ttcaaaaaggattcgtccgtgttcatcctggggaacacagacaggccggatgcctccgct atttacctgcatgacttccagaggtttctcatacatgaacagcaggagcattgggctcag gatctgagcaaagttcgtgagcggatgacaaagttcatcgatgacaccatgcgcgaaact gctgagcctttcttgtttgtggatgagttcctcacgtacctgttttcacgagaaaacagc atctgggatgagaagtatgacgcggtggacatgcaggacatgaacaaccccctgtctcat tactggatctcctcgtcacataacacgtacctcacaggtgaccagctgcggagcgagtcg tccccggaagcttacatccgctgcctgcgcatgggctgtcgctgcattgaactggactgc tgggacgggcccgatgggaagcccatcatctaccacggctggacgcggaccaccaagatc aagtttgacgacgtcgtacaggccatcaaagagcacgcctttgttacctcaagcttccca gtgatcctgtccatcgaggagcactgcagtgtggagcagcagcgtcacatggccaagacc ttcaaggaagtgtttggcgacctgctgctgatgaagcccacggaggccagcgctgaccag ctgccctcgcccagccagctgcgggagaagatcatcatcaagcataagaaactgggtccc cgaggcgacgtggatgtcaacgtggaggacaagaaggatgagcacaagcaacagggagag ctgtacatgtgggattccattgaccagaaatggactcggcactactgcgccgttgccgat gccaagctgtccttcagtgatgacattgaacagactacggaggaggaagtgccccaggat ataccccctacagagctacattttggggagaaatggttccacaagaaggtggagaagagg acgagtgccgagaagttgctgcaggaatactgcatggagacggggggcaaggacggcacc ttcctggttcgggagagcgagaccttccccaatgactacaccctgtccttctggcggtca ggccgggtccagcactgccggatccgttccaccacggagggtggaaccctgaagtactac ctgactgacaacctcaccttcagcagcatctacgccctcatccagcactaccgcgagacg cacctgcgctgcgccgagttcgagctgcggctcacggaccctgtgcccaaccccaacccc cacgagtccaagccgtggtactatgagagcctgagccgcggagaggcagaggacatgctg atgaggatcccccgggacggagccttcctgatccggaagcgagagggaagcgactcctac gccatcaccttcagggctaggggcaaggtgaagcattgtcgaatcaaccgggatggccgg cactttgtgctggggacctccgcctattttgagagcctggtggagctcgtcagttactac gagaagcattcactctaccgaaagatgagactgcgctaccccgtgacccccgagctcctg gagcgctacaacatggaaagagatataaactccctctacgacgtcagcagaatgtatgtg gatcccagtgaaatcaatccatccatgcctcagagaaccgtgaaagctctgtatgactac aaagccaagcgaagcgatgagctgagcttctgccgtggcgctctcatccacaatgtctcc aaggagcccgggggctggtggaaaggagactatggaaccaggatccagcagtacttccca tccaactacgtcgaggacatctcaacggcagatgtcgaggagctggaaaagcagattatt gaagacaatcccttagggtctctttgcagaggaatattggacctcaatacctataacgtc gtgaaagccccacagggaaaaaaccagaagccctttgtcttcatcctggagcccaagaag cagggcgatcctccggtggagtttgccacagacagggtggaggagctcttcgagtggttt cagagcatccgagagatcacctggaagattgacaccaaggagaacaacatgaagtactgg gagaagaaccagtccatcgccatcgagctctctgacctggttgtctactgcaaaccaacc agcaaaaccaaggacaacttagaaaatcctgatttccgagaaatccgctcctttgtggaa acgaaggctgacagcatcaccagacagaagcccgtcgacctcctgaggtataatcaaaag ggcctgacccgcgtctacccaaagggacaaagagttgactcttcaaactacgaccccttc cgcctctggctgtgcggttctcagatggtggcactcaatttccagacggcagataagttc atgcagatgaatcacgcgttgttttctctcaatgggcgcacgggctacgttctgcagccc gagagcatgagggcagagaaatatgacccaatgccacccgagtcccagaggaagatcctg atgacgctgacggtcaaggttctcggtgctcgccatctccccaaacttggacgaagtatt gcctgtccctttgtagaggtggagatctgtggagccgactatgacaacaacaagttcaag acgacggttgtgaatgataatggcctcagccctatctgggctccaacacaggagaaggtg acatttgaaatttatgacccaaacctggcatttctgcgctttgtggtttacgaagaagat atgttcagtgatcccaactttcttgctcatgccacttaccccattaaagcaatcaaatca ggattcaggtctgttcctctgaagaatgggtacagcgaggacatagagctggcttccctc ctggttttctgtgagatgcggccagtcctggagagcgaagaggaactttactcctcctgt cgccagctaaggaggcggcaagaagaactgaacaaccaactctttctgtatgacacacac cagaacttgcgcaatgccaaccgggatgccctggttaaagagttcaatgttaatgagaac cagctccagctgtaccaggagaaatgcaacaagaggttaagagagaagagagtcagcaac agcaagttttactcatag

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