Chlorocebus sabaeus (green monkey): 103234360 Help Entry 103234360         CDS       T04361                                  Symbol TYK2 Name (RefSeq) tyrosine kinase 2   KO K11219   non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] Organism csab  Chlorocebus sabaeus (green monkey) Pathway csab04217   Necroptosis csab04380   Osteoclast differentiation csab04620   Toll-like receptor signaling pathway csab04621   NOD-like receptor signaling pathway csab04630   JAK-STAT signaling pathway csab04658   Th1 and Th2 cell differentiation csab04659   Th17 cell differentiation csab05145   Toxoplasmosis csab05160   Hepatitis C csab05161   Hepatitis B csab05162   Measles csab05164   Influenza A csab05165   Human papillomavirus infection csab05167   Kaposi sarcoma-associated herpesvirus infection csab05168   Herpes simplex virus 1 infection csab05169   Epstein-Barr virus infection csab05171   Coronavirus disease - COVID-19 Brite KEGG Orthology (KO) [BR:csab00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     103234360 (TYK2)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     103234360 (TYK2)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     103234360 (TYK2)    04621 NOD-like receptor signaling pathway     103234360 (TYK2)    04658 Th1 and Th2 cell differentiation     103234360 (TYK2)    04659 Th17 cell differentiation     103234360 (TYK2)   09158 Development and regeneration    04380 Osteoclast differentiation     103234360 (TYK2)  09160 Human Diseases   09172 Infectious disease: viral    05161 Hepatitis B     103234360 (TYK2)    05160 Hepatitis C     103234360 (TYK2)    05171 Coronavirus disease - COVID-19     103234360 (TYK2)    05164 Influenza A     103234360 (TYK2)    05162 Measles     103234360 (TYK2)    05168 Herpes simplex virus 1 infection     103234360 (TYK2)    05167 Kaposi sarcoma-associated herpesvirus infection     103234360 (TYK2)    05169 Epstein-Barr virus infection     103234360 (TYK2)    05165 Human papillomavirus infection     103234360 (TYK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     103234360 (TYK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:csab01001]     103234360 (TYK2) Enzymes [BR:csab01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      103234360 (TYK2) Protein kinases [BR:csab01001]  Non-receptor tyrosine kinases   JAK family [OT]    103234360 (TYK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Jak1_Phl Pkinase FERM_F2 FERM_F1 SH2_1 Kdo Kinase-like ABC1 Motif Other DBs NCBI-GeneID:  103234360 NCBI-ProteinID:  XP_007994269 Ensembl:  ENSCSAG00000007285 LinkDB All DBs Position 6:complement(9399945..9420054) Genome browser AA seq 1142 aa AA seqDB search MGGGVSAGDVVAVRGGGVGSGFELLSPGKAEPPAGSMPLRHRGTTRGSKPVGDGAQPMAA MGGLKVLLHWAGPGGREPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVW LPPNHILEIPRDASLMLYFRMRFYFQNWHGMNPQEPAVYRCGPPGTEASSDQTAQGMQLL DPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFKNESLGMAFLHLCHLALRRGVPLEE VAKKTSFKDCIPLSFRRQIRQHSALTRLRLWNVFRRFLQDFQPDRLSQQMVMVKYLATLE RLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGEAPTDPGPESAAGPPTHEVLVTGTGGI QWRPVQEEVNKEEGSSGGSSRNPQASLSGKKAKAHKAIGQPADRLREPLWAYFCDFRDIT HVVLKERCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLV MSIQDGIHGPLLEPFVQAKLRPEDGLYLIQWSTSHPYRLILTVAQRSQAPDGTQSLRLRK FPIEQQAGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIVM RGARASTRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE DPLLPGRDRGQELRVVLKVLDPSHHDIALVSGRARPGGSGGGGMGGVCLEERAEAGRSPQ SSCVFADIMVTEYVEHGPLDVWLRRKRGHVPMAWKMVVAQQLASALSYLCSQLCIILDSK WIQLLQEKVFLPLGSDPGVAVAGFVTPKCVPAGERIGVRPLTTAALPDLADVLIVNPDSS ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK QEIEILRTLYHEHIVKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQ QICEGMAYLHAQHYIHRDLAARNVLLDNDKLVKIGDFGLAKAVPEGHEYYRVREDGDSPV FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGSTQGQMTVLRLT ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFKNLIPILKTVHEKYQGQAPSVFS VC NT seq 3429 nt NT seq  +upstreamnt  +downstreamnt atgggaggaggcgtctcggcgggggacgtagtggctgtccgcgggggcggggtggggtcc gggttcgagctcttgtcccccgggaaggccgagccacctgctgggagcatgcctctgcgc catcgggggacgaccaggggcagcaagcccgttggggatggagcccagcccatggctgcc atgggaggcctgaaggtgcttctgcactgggctggtccaggcggcagagagccctgggtc actttcagcgagtcatcgctgacagctgaggaagtctgcatccacatcgcacataaagtc ggtatcactcctccttgtttcaatctcttcgccctcttcgatgctcaggcccaagtctgg ttgcccccaaaccacatcctagagatccccagagacgcaagcctgatgctgtatttccgc atgaggttttatttccagaactggcatggcatgaatcctcaggagccagctgtgtaccgt tgtgggcccccaggaaccgaggcatcctcagatcagacagcacaggggatgcaactcctg gacccagcctcatttgagtacctctttgagcagggcaagcatgagtttgtgaatgatgtg gcgtcactgtgggagctgtcgagtgaggaggagatccaccactttaagaatgagagccta ggcatggcctttctgcacctctgtcacctcgctctccgccgtggtgtccccctggaggag gtggccaagaagaccagcttcaaggactgcatcccgctctccttccgtcggcagatccgg cagcacagcgccctgacccggctgcgcctttggaacgtcttccgcaggttcctgcaggac ttccagccagacagactctcccagcagatggtcatggtcaaatacctggccacacttgaa cggctggcaccccgctttggcacagagcgtgtgcccgtgtgccacctgaggctgctggcc caggcagagggggagccctgctacatccgggacagtggggaggcacctacagaccctggc cccgagtctgctgctggacccccaacccatgaggtgctggtgacaggcactggtggcatc cagtggcggccagtacaggaggaggtgaacaaggaggagggttctagtggcggcagcagc aggaacccccaagccagcctgtctgggaagaaggccaaggctcacaaggcaattggccag ccggcggacaggctgcgggagccactgtgggcctacttctgcgacttccgggacatcacc cacgtggtgctgaaagagcgctgtgtcagcatccaccggcaggacaacaagtgcctggag ctgagcctgccttcccgggctgcggcgctgtccttcgtgtcgctggtggacggctatttc cgcctgacggccgactccagccactacctgtgccacgaggtggctcccccacggctggtg atgagcatccaggatgggatccacggacccctgctggagccgtttgtgcaggccaagctg cggcccgaggacggcctgtacctcattcagtggagcaccagccacccctaccgcctgatc ctcacagtggcccagcgtagccaggcaccagacggcacacagagcttgcggctccggaag ttccccattgagcagcaggccggggcctttgtgctggagggctggggccggtccttcccc agtgttcgggaacttggggccgccttgcagggctgcttgctgagggccggggacgactgc ttctctctgcgtcgctgttgcctgccccaaccaggagaaacctccaacctcatcgtcatg cggggggctcgggccagcaccaggacactcaacctcagccagctcagcttccaccgggtt gaccagaaggagatcacccagctgtcccacttgggccagggcacaaggaccaacgtgtac gagggccgcctgcgagtggagggcagtggggaccctgaggagggcaagatggacgacgag gatcccctcctgcctggaagggaccgtgggcaggagctacgagtggtgctcaaagtgctg gacccaagtcaccatgatatcgccctggtgagtggcagggccaggcctggggggtctgga ggaggcgggatgggaggggtgtgtctggaggagagggcagaagcaggcaggtcgccccag agcagctgtgtctttgcagatatcatggtgacagagtacgtggagcacggacccctggac gtgtggctgcggaggaagcggggccatgtgcccatggcttggaagatggtggtggcccag cagctggccagcgccctcagctacctgtgcagccaactctgcatcattttggacagtaag tggattcagctgttgcaggaaaaagttttcttacctctgggatcagatcctggggtagct gtagctggctttgtaactcccaagtgtgtgcctgctggggaaaggatcggggtcaggcct ttaaccaccgcagctcttccagatcttgctgatgtcttgattgtgaacccggactcatcg gcgtcagaccctacggttttccacaagcgctatttgaaaaagatccgagatctgggcgag ggtcacttcggcaaggtcagtttgtactgctacgatccgaccaacgacggcactggcgag atggtggcggtgaaagcccttaaggcagactgcggcccccagcaccgctcgggctggaag caggagattgagattctgcgcacgctctatcacgagcacatcgtcaagtacaagggctgc tgcgaggaccaaggcgagaagtcgctgcagctggtcatggagtacgtgcccctgggcagc ctccgagactacctgccccggcacagcgtcgggctggcccagctgctgctcttcgcccag cagatctgcgagggcatggcctatctgcacgcgcagcactacatccaccgagacctagcc gcgcgcaacgtgctgctggacaacgacaagctggtcaagatcggggactttggcctagcc aaggccgtgcccgaaggccacgagtactaccgcgtgcgcgaggatggggacagccccgtg ttctggtatgccccagagtgcctgaaagagtataagttctactatgcgtccgatgtctgg tccttcggggtgaccctgtatgagctgctgacgcactgtgactccagccagagccccccc acgaaattccttgagctcataggcagcacccagggtcagatgacagttctgagactcacc gagttgctggaacgaggggagaggctgccacgacctgacaaatgtccctgtgaggtctat catctcatgaagaactgctgggagacagaggcgtccttccgcccaaccttcaagaacctc atacccatcctgaagacagtccatgagaagtaccaaggccaggccccttccgtgttcagc gtgtgctga

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