Chlorocebus sabaeus (green monkey): 103238159
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Entry
103238159 CDS
T04361
Symbol
LRRK2
Name
(RefSeq) leucine rich repeat kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
csab
Chlorocebus sabaeus (green monkey)
Pathway
csab05012
Parkinson disease
csab05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
csab00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
103238159 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
103238159 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
csab01001
]
103238159 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
csab04131
]
103238159 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
csab04147
]
103238159 (LRRK2)
Enzymes [BR:
csab01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103238159 (LRRK2)
Protein kinases [BR:
csab01001
]
Serine/threonine kinases: TKL group
LRRK family
103238159 (LRRK2)
Membrane trafficking [BR:
csab04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
103238159 (LRRK2)
Exosome [BR:
csab04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
103238159 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
COR
LRR_4
Ras
LRR_14
LRR_9
WDR55
LRR_13
Arf
Beta-prop_EML_2
LRR_NXF1-5
Beta-prop_RSE1_2nd
WD40_CDC20-Fz
T2SSE
Ank_2
Beta-prop_BBS7
AAA_22
LRR_6
nSTAND3
AAA_7
WD40_like
AAA_16
PduV-EutP
Kdo
Septin
GTP_EFTU
NACHT
ABC_tran
cobW
MMR_HSR1
MobB
WD40_Prp19
G-alpha
TrwB_AAD_bind
FtsK_SpoIIIE
TsaE
TniB
WD40_WDHD1_1st
AAA_29
ARM_LIN_2nd
Motif
Other DBs
NCBI-GeneID:
103238159
NCBI-ProteinID:
XP_008001071
Ensembl:
ENSCSAG00000007254
UniProt:
A0A0D9R4H9
LinkDB
All DBs
Position
11:36490775..36634215
Genome browser
AA seq
2527 aa
AA seq
DB search
MASGSCQGCEEDEETLKKLIVRLNNVQEGKQIETLVQILEDLLVFTYSEHASKLFQGKNI
HVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPGTMQSLMGPQDVGNDWEVLGVHQLILK
MLTVHNASVNLSMIGLKTLDLLLTSGKITLLILDEESDIFMLIFDAMHSFPANDEIQKLG
CKALHVLFERVSEEQLTEFVENKDYMILLSALTNFKDEEEIVLHVLHCLHSLAIPCNNVE
VLMSGNVRCYNIVVEAMKAFPISEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAVQ
RYPENAALQISALSCLALLTETIFLNQDLEEKNENQENDDEGEEVKLFWLEACYKALTWH
RKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGHFPAHREVMLSMLMHSSSKEVFQASAN
ALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNTSLDTL
AAVVPKIVTVMKSHETSLPVQLEALRAILHFIAPGMPEESREDAESHRKLNMVKKQCFAN
DIHKLVLAALNRFIGNPGIQKCGLKVISSIAHFTNTLEVLSMEGAVDSVLHTLQMYPDDQ
EIQCLGLSLIGCLITKKNLCIGTGHLLAKILASSLYRFKDVAEVQTEGFQTILAILKLSA
SFSKLLVHHSFDLVIFHQMSSSIMEQKDQQFLNLCCKCFAKVAMDDDLKNVMLERACDQN
NSIMAECLLLLGADANQAKEGTSLICQVCEKESSPKLVELLLNSGSREQDVRKALTISIG
KGDSQIISLLLRRLALDMANNSICLGGFCIGKVEPSWLGPLFPDKTSNLRKQTNIASTLA
RMVIRYQMKSAVEEGAALGSDGNFSEDVLSKFDEWTFIPDSSMDSVFAQSDDLDSEGSEG
SFLVKKKSNSISVGEFYRDAVLQRCSPNLQRHSSSLGPIFDHEDLLRRKRKILSSDDSLR
SSKLQSHVRHSDSISSLASEREYITSLDLSANELRDIDALSQKSCISGHLEHLEKLELHQ
NALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCVANLDVSRNDIGPSVVLDPAV
KCPTLKQFNLSYNQLSSVPENLADVIEKLEQLILEGNKISGICSPLRLKELKILNLSKNH
ISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTSLKLSQNKFTCIPEAILNLPHLRS
LDMSSNDIQCLPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEI
PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDIIR
FLQQRLKKAVPYNRMKLMVVGNTGSGKTTLLQQLMKTKKSDLGMQSATVGIDVKDWPIQI
RGKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
RASSSPVILVGTHLDVSDERQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKL
RKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDQKRLLQLVREN
QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGCPK
HPKGIISRRDVEKFLSKKRRFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
NWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDI
CGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLI
LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQE
LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVAD
GLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELAIQGKLPDPVKEYG
CTPWPMVEKLITKCLKENPQERPTSAQVFDILNSAELVCLTRHILLPKNVIVDCMVATHH
NSRNASIWLGCGHTDRGQLSFLDLNTEGYTSEEVADSRILCLALVHLPVQKESWIVSGTQ
SGTLLVINTEDGKKRHTLEKMTDSITCLYCNSFSKQSKQKNFLLVGTADGNLAIFEDKTV
KLEGAAPLKILNIGNVSTPLMCLSESTNSTERNVMWGGCGTKIFSFSNDFTIQKLIETRT
SQLFSYAAFSDSNIVTVVVDTALYIAKKNSPVVEVWDKKTEKLCELIDCVHFLREVMVKV
NKESKHKMSYSGRVKALCLQKNTALWIGTGGGHILLLDLSTRRVIRIIYNFCDSVRVMMT
AQLGSLKNVMLVLGYNRKSTEGTQQQKEIQSCLTVWDINLPHEVQNLEKHIEVRKELAEK
MRGTSIE
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggctagtggcagctgtcaggggtgcgaggaggacgaggaaactctgaagaagttgata
gtcaggctgaacaatgtccaggaaggtaaacagatagaaacgctggttcaaatcctggag
gatctgctggtgttcacgtactccgagcacgcctccaagttatttcaaggcaaaaatatc
catgtgcctctgttgatcgtcttggactcgtatatgagagtcgcgagtgtgcagcaggtg
ggttggtcacttctgtgcaaattaatagaaatctgtccgggtacaatgcaaagcttaatg
ggaccccaggatgttggaaatgattgggaagtccttggtgttcaccaattgattcttaaa
atgctaacagttcataatgccagtgtaaacttgtcaatgattggactgaagaccttagat
ctcctcctaacttcaggtaaaatcaccttactgatattggatgaagaaagtgatattttc
atgttaatttttgatgccatgcactcatttccagccaatgatgaaatccagaaacttgga
tgcaaagctttacatgtgctgtttgagagagtctcagaggagcaactaactgaatttgtt
gagaacaaagattatatgatattgttaagtgcgttaacaaattttaaagatgaagaggaa
attgtgcttcatgtactgcattgtttacattccctagcaattccttgcaataatgtggaa
gtcctcatgagtggcaatgtcaggtgttataatattgtggtggaagctatgaaagcattc
cctatcagtgaaaaaattcaagaagtgagttgctgtttgctccataggcttacattaggt
aatttttttaatatcctggtattaaacgaagtccatgaatttgtggtgaaagctgtgcag
cggtacccagagaacgcagcattacagatctcagcgctcagctgtttggccctcctcact
gagaccattttcttaaatcaagatttagaggaaaagaatgagaatcaagagaatgatgat
gagggggaagaagttaaattgttttggctggaagcctgttacaaagcattaacgtggcat
agaaagaacaagcacgtgcaggaggctgcatgctgggcactaaataatctccttatgtac
caaaacagtttacatgagaagattggagatgaagatggccatttcccagctcatagggaa
gtgatgctgtccatgctgatgcattcttcatcaaaggaagttttccaggcatctgctaat
gcattgtcaactcttttagaacaaaatgttaatttcagaaaaatcctgttatcaaaagga
atatacctgaatgttttggagttaatgcagaagcatatacattctcctgaagtggctgaa
agtggctgcaaaatgctaaatcatctttttgaaggaagcaacacttccctggatacattg
gcagcagtggtccccaaaatagtaacagttatgaaaagtcatgagacatcattaccagtg
cagctggaggcgcttcgagctattttacattttatagcgccaggcatgccagaagaatcc
agagaggatgcagaatctcatcgtaagctaaatatggttaaaaaacagtgttttgcgaat
gatattcacaaactggtcctagcagctttgaacaggttcattggaaatcctgggattcag
aaatgtggattaaaagtaatttcttctattgcacattttactaatacattagaggtgtta
tccatggaaggtgctgtggattcagtgcttcacacactgcagatgtatccagatgaccaa
gaaattcagtgtctgggtttaagtcttataggatgcttgattacaaagaagaatttatgc
ataggaactggacatctgctggcaaaaattctggcttccagcttataccgatttaaggat
gttgctgaagtacagactgaaggatttcagacaatcttagcaatcctcaaattgtcagca
tctttttctaagctgctggtgcatcattcgtttgacttagtaatattccatcaaatgtct
tccagtatcatggaacaaaaggatcaacagtttctaaacctgtgttgcaagtgttttgca
aaagtagctatggatgatgacttaaaaaatgtgatgctagagagagcgtgtgatcagaat
aacagcatcatggctgaatgcttgcttctcttaggagcagatgccaatcaagcaaaggag
ggaacttctttaatttgtcaggtatgtgagaaagagagcagtcccaaattggtggaactc
ttattgaatagtggatctcgtgaacaagatgtacgaaaagcactgacaataagcattggg
aaaggcgacagccagatcatcagcttgctcttaaggaggctggccctggacatggccaac
aatagcatttgccttggagggttttgtataggaaaagttgaaccttcttggcttggtcct
ttatttccagataagacttctaatttaaggaaacaaacaaatatagcatctacactagca
agaatggtgatcagatatcagatgaaaagtgccgtggaagaaggagcagccttaggcagt
gatggaaatttttctgaagatgtgctgtctaaatttgatgaatggacctttattcctgac
tcttctatggacagtgtctttgctcaaagtgatgatctagatagtgaaggaagtgaaggc
tcatttcttgtgaaaaagaaatcaaattcaattagtgtaggagaattttaccgagatgcc
gtattacaacgttgctcaccaaatttgcaaaggcattccagttccttggggcccattttt
gatcatgaagatttactgaggagaaaaagaaaaatattatcttcagatgattcactcagg
tcatcaaaacttcaatcccatgtgaggcattcagacagcatttcttctctggcttctgag
agagaatatattacatcactagacctttcagcaaatgaactaagagatattgatgcccta
agccagaaatcctgtataagtggtcatttggagcatcttgaaaagctggagcttcaccag
aatgcactcacgagctttccacaacagctatgtgaaactctgaagagtttgacacatttg
gacttgcacagtaataaatttacatcatttccttcttacttgttgaaaatgagttgtgtt
gctaaccttgatgtctctcgaaatgacattggaccctcagtggttttagatcctgcagtg
aaatgtccaactctgaaacagtttaacctgtcatataaccagctgtcttctgttcctgag
aaccttgctgatgtgatagagaaactggagcagctcattttagaaggaaataaaatatca
gggatatgctcccccttgagactgaaggaactgaagattttaaaccttagtaaaaaccac
atttcatccctatcagagaactttcttgaggcttgtcctaaagtggagagtttcagtgcc
agaatgaattttcttgctgctatgcctttcttgcctccttccatgacaagcctaaaatta
tctcaaaacaaatttacatgtattccagaagcaattttaaatcttccacacttgcggtct
ttagatatgagcagcaatgatattcaatgtctaccaggtcctgcacactggaaatctttg
aacttaagggaactcttatttagccataatcagatcagcatcttggacttgagtgaaaaa
gcatatttatggtctagagtagagaaactgcatctttctcacaataaactgaaagagatt
cctcctgagattggctgtcttgaaaatctgacatctctggatgtcagttacaacttggaa
ctaagatcctttcccaatgaaatggggaaattaagcaaaatatgggatcttcctttggat
gaactgcgtcttaactttgattttaaacatataggatgtaaagccaaagacatcataagg
tttcttcaacagcggttaaaaaaggctgtgccctataaccgaatgaaactgatggttgtt
ggaaatactgggagtggtaaaaccaccttattgcagcaattaatgaaaaccaagaaatca
gatcttggaatgcaaagtgccacagttggcatagatgtgaaagactggcctatccaaata
aggggcaaaagaaagagagatctcgttctgaatgtgtgggattttgcaggtcgtgaggaa
ttctatagtactcatcctcattttatgacgcagcgagcattgtaccttgctgtctatgac
cttagcaaaggacaggctgaagttgatgccatgaagccttggctcttcaatataaaggct
cgcgcttcttcttcccctgtgattctcgttggtacacatttggatgtttctgatgagagg
cagcgcaaagcctgcataagtaaaatcaccaaggaactcctgaataagcgagggttccct
gctatacgagattaccactttgtgaatgccaccgaggaatctgatgctttggcaaaactt
cggaaaaccatcataaacgagagccttaatttcaagatccgagatcagcctgttgttgga
cagctgattccagactgctatgtagaacttgagaaaatcattttatcggagcgtaaaaat
gtgccaattgaatttcctgtaattgaccagaaacgattattacaactagtgagagaaaat
cagttgcagttagatgaaaatgagcttcctcacgcagttcactttctaaatgaatcagga
gtccttcttcattttcaagacccagcactgcagttaagtgacttgtattttgtggaaccc
aagtggctttgtaaaatcatggcacagattttgacagtgaaagtggaaggttgtccaaaa
caccctaagggaattatttcacgtagagatgtggaaaaatttctttcgaagaaaaggaga
tttccaaagaactacatgtcacagtattttaagctcctagaaaaattccagattgctttg
ccaataggagaagaatatttgctggttccaagcagtttgtctgaccacaggcctgtgata
gagcttccccattgtgagaactctgaaattatcatccgactatatgaaatgccttatttt
ccaatgggattttggtcgaggttaatcaatcgattacttgagatttcaccttacatgctt
tcagggagagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctactta
aattggtctcctgaagcttattgtctggtgggatctgaagtcttagacaatcacccagag
agtttcttaaaaattacagttccttcttgtagaaaaggctgtattcttttgggccaagtt
gtggaccacattgattctctcatggaggaatggtttcctgggttgctggagattgatatt
tgtggtgaaggagaaactctgttgaagaaatgggcattatatagttttaatgatggtgaa
gagcatcaaaaaatcttacttgatgacttgatgaagaaagcagaggaaggagatctctta
gtaaatccagatcaaccaaggctcaccattccaatatctcagattgcccctgacttgatt
ttggctgacctgcctagaaatattatgttgaataatgatgagctggaatttgaacaagct
ccagagtttctcctaggtgatggcagttttggatcagtttatcgagcagcctatgaagga
gaagaagtggctgtgaagatttttaataaacacacatcacttaggctgttaagacaagag
ctggtggtgctttgccacctccaccaccccagtttgatatctttgctggcagctggtatt
cgtccccggatgttggtgatggagttagcctccaagggttccttggatcgcctgcttcag
caggacaaagccagcctcactagaaccctacagcacaggattgcactccatgtggctgac
ggtttgagatacctccattcagccatgattatataccgagacttgaagccccacaatgtg
ctgcttttcacactgtatcccaatgctgccatcattgcaaagattgctgactatggcatt
gctcagtactgctgtagaatggggataaaaacgtcagagggcacaccagggtttcgtgca
cctgaagttgccagaggaaatgtcatttataatcaacaagctgatgtttattcatttggt
ttgctactctatgacattttgacaactggaggtagaatagtagagggtttgaagtttcca
aatgagtttgatgaattagcaatacaaggaaaattacctgatccagttaaagaatatggt
tgtaccccatggcctatggttgagaaattaattacaaagtgtttgaaagaaaatcctcaa
gaaaggcctacttctgcccaggtctttgacattttgaattcagctgaattagtctgtctg
acgagacacattttattacctaaaaacgtaattgttgactgcatggttgctacacatcac
aacagcaggaatgcaagcatttggctgggctgtgggcacactgacagaggacagctctca
tttcttgacttaaatactgaaggatacacttctgaggaggttgctgatagtagaatattg
tgcttagccttggtgcatcttcctgttcaaaaagaaagctggattgtgtccgggacacag
tctggtactctcctggtcatcaataccgaagatgggaaaaagagacataccctagaaaag
atgactgattccatcacttgtttgtattgcaattccttttccaagcaaagcaaacaaaaa
aattttcttttggttggaaccgctgatggcaatttagcaatttttgaagataaaactgtt
aagctcgaaggagctgctcctttgaagatactaaatataggaaatgtcagtactccattg
atgtgtttgagtgaatccacaaattcaacagaaagaaatgtaatgtggggaggatgtggc
acgaagattttctccttttctaatgatttcaccattcagaaactcattgagacaagaaca
agccaactgttttcttatgcagctttcagtgattccaacatcgtaacagtggtggtagac
actgctctctatattgctaagaaaaatagccctgttgtggaagtgtgggataagaaaact
gaaaaactctgcgaactaatagactgtgtgcactttttaagggaggtaatggtaaaagta
aacaaggaatcaaaacacaaaatgtcttattctgggagagtgaaagctctctgccttcag
aagaacactgctctttggataggaactggaggaggccatattttactcctggatctttca
actcgtcgagttatacgtataatttacaacttttgtgattcggtcagagtcatgatgaca
gcacagctagggagccttaaaaatgtcatgctggtattgggctataaccggaaaagtact
gaaggtacacaacagcagaaagagatacaatcttgcttgactgtttgggacatcaatctt
ccacatgaagtgcaaaatttagaaaaacacattgaagtgagaaaagaattagctgaaaaa
atgagaggaacatctattgaataa
DBGET
integrated database retrieval system
