Chlorocebus sabaeus (green monkey): 103245842 Help Entry 103245842         CDS       T04361                                  Symbol PLCB2 Name (RefSeq) phospholipase C beta 2   KO K05858   phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] Organism csab  Chlorocebus sabaeus (green monkey) Pathway csab00562   Inositol phosphate metabolism csab01100   Metabolic pathways csab04015   Rap1 signaling pathway csab04020   Calcium signaling pathway csab04022   cGMP-PKG signaling pathway csab04062   Chemokine signaling pathway csab04070   Phosphatidylinositol signaling system csab04071   Sphingolipid signaling pathway csab04072   Phospholipase D signaling pathway csab04081   Hormone signaling csab04082   Neuroactive ligand signaling csab04261   Adrenergic signaling in cardiomyocytes csab04270   Vascular smooth muscle contraction csab04310   Wnt signaling pathway csab04371   Apelin signaling pathway csab04540   Gap junction csab04611   Platelet activation csab04613   Neutrophil extracellular trap formation csab04621   NOD-like receptor signaling pathway csab04713   Circadian entrainment csab04720   Long-term potentiation csab04723   Retrograde endocannabinoid signaling csab04724   Glutamatergic synapse csab04725   Cholinergic synapse csab04726   Serotonergic synapse csab04728   Dopaminergic synapse csab04730   Long-term depression csab04742   Taste transduction csab04750   Inflammatory mediator regulation of TRP channels csab04911   Insulin secretion csab04912   GnRH signaling pathway csab04915   Estrogen signaling pathway csab04916   Melanogenesis csab04918   Thyroid hormone synthesis csab04919   Thyroid hormone signaling pathway csab04921   Oxytocin signaling pathway csab04922   Glucagon signaling pathway csab04924   Renin secretion csab04925   Aldosterone synthesis and secretion csab04926   Relaxin signaling pathway csab04927   Cortisol synthesis and secretion csab04928   Parathyroid hormone synthesis, secretion and action csab04929   GnRH secretion csab04933   AGE-RAGE signaling pathway in diabetic complications csab04934   Cushing syndrome csab04935   Growth hormone synthesis, secretion and action csab04961   Endocrine and other factor-regulated calcium reabsorption csab04970   Salivary secretion csab04971   Gastric acid secretion csab04972   Pancreatic secretion csab04973   Carbohydrate digestion and absorption csab05010   Alzheimer disease csab05016   Huntington disease csab05017   Spinocerebellar ataxia csab05022   Pathways of neurodegeneration - multiple diseases csab05142   Chagas disease csab05143   African trypanosomiasis csab05146   Amoebiasis csab05163   Human cytomegalovirus infection csab05200   Pathways in cancer csab05415   Diabetic cardiomyopathy csab05417   Lipid and atherosclerosis Module csab_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:csab00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     103245842 (PLCB2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103245842 (PLCB2)    04310 Wnt signaling pathway     103245842 (PLCB2)    04070 Phosphatidylinositol signaling system     103245842 (PLCB2)    04072 Phospholipase D signaling pathway     103245842 (PLCB2)    04071 Sphingolipid signaling pathway     103245842 (PLCB2)    04022 cGMP-PKG signaling pathway     103245842 (PLCB2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     103245842 (PLCB2)    04081 Hormone signaling     103245842 (PLCB2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103245842 (PLCB2)    04613 Neutrophil extracellular trap formation     103245842 (PLCB2)    04062 Chemokine signaling pathway     103245842 (PLCB2)   09152 Endocrine system    04911 Insulin secretion     103245842 (PLCB2)    04922 Glucagon signaling pathway     103245842 (PLCB2)    04929 GnRH secretion     103245842 (PLCB2)    04915 Estrogen signaling pathway     103245842 (PLCB2)    04921 Oxytocin signaling pathway     103245842 (PLCB2)    04926 Relaxin signaling pathway     103245842 (PLCB2)    04935 Growth hormone synthesis, secretion and action     103245842 (PLCB2)    04918 Thyroid hormone synthesis     103245842 (PLCB2)    04919 Thyroid hormone signaling pathway     103245842 (PLCB2)    04928 Parathyroid hormone synthesis, secretion and action     103245842 (PLCB2)    04924 Renin secretion     103245842 (PLCB2)    04925 Aldosterone synthesis and secretion     103245842 (PLCB2)    04927 Cortisol synthesis and secretion     103245842 (PLCB2)   09154 Digestive system    04970 Salivary secretion     103245842 (PLCB2)    04971 Gastric acid secretion     103245842 (PLCB2)    04972 Pancreatic secretion     103245842 (PLCB2)    04973 Carbohydrate digestion and absorption     103245842 (PLCB2)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     103245842 (PLCB2)   09156 Nervous system    04724 Glutamatergic synapse     103245842 (PLCB2)    04725 Cholinergic synapse     103245842 (PLCB2)    04728 Dopaminergic synapse     103245842 (PLCB2)    04726 Serotonergic synapse     103245842 (PLCB2)    04720 Long-term potentiation     103245842 (PLCB2)    04730 Long-term depression     103245842 (PLCB2)    04723 Retrograde endocannabinoid signaling     103245842 (PLCB2)   09157 Sensory system    04742 Taste transduction     103245842 (PLCB2)    04750 Inflammatory mediator regulation of TRP channels     103245842 (PLCB2)   09159 Environmental adaptation    04713 Circadian entrainment     103245842 (PLCB2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103245842 (PLCB2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     103245842 (PLCB2)   09174 Infectious disease: parasitic    05146 Amoebiasis     103245842 (PLCB2)    05142 Chagas disease     103245842 (PLCB2)    05143 African trypanosomiasis     103245842 (PLCB2)   09164 Neurodegenerative disease    05010 Alzheimer disease     103245842 (PLCB2)    05016 Huntington disease     103245842 (PLCB2)    05017 Spinocerebellar ataxia     103245842 (PLCB2)    05022 Pathways of neurodegeneration - multiple diseases     103245842 (PLCB2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     103245842 (PLCB2)    05415 Diabetic cardiomyopathy     103245842 (PLCB2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     103245842 (PLCB2)    04934 Cushing syndrome     103245842 (PLCB2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:csab04131]     103245842 (PLCB2) Enzymes [BR:csab01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      103245842 (PLCB2) Membrane trafficking [BR:csab04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     103245842 (PLCB2)  Endocytosis   Macropinocytosis    Phospholipase C     103245842 (PLCB2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh C2 EF-hand_like AAA_13 Motif Other DBs NCBI-GeneID:  103245842 NCBI-ProteinID:  XP_008015234 Ensembl:  ENSCSAG00000007432 UniProt:  A0A0D9R4V3 LinkDB All DBs Position 26:42706462..42727516 Genome browser AA seq 1185 aa AA seqDB search MSLLNPVLLPPRVKAYLSQGERFIKWDDETTIASPVILRVDPKGYYLYWTYQSKEMEFLD ITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKE NVGKVWAEDILALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNFFQMFPADRKR VEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEH LTKFINQKQRDSRLNSLLFPPAQPDQVQGLIDKYEPSGINVQRGQLSPEGMVWFLSGPEN SVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDC WKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKM AEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSSPTSSSKDPGGE AEGSSPRSAPAGEGTVWAGEEGTELEDEEVEEEEEEESGNLDEEEIKKMQSDEGTAGLEV TAYEEMSSLVNYIQPTKFISFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQM SRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEF MRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRT KLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHL CLHSESNMPLTMPALFVFLEMKDYVPGAWADLTVALANPIKFFNAHDKRSVKLKEVMGGL PEKPFPLASPVASQVNGALAPRSNGSPAARAWAGEEAIKEVAEPRTASLEELRELKGVVK LQRRHEKELRELERRGARRWEELLQRGAAQLAELGPRGAGGGGAGKLGPGKGSRKKRSLP CEESAGAAPGEGPEGMDARVRELKDRLELELLRQGEEQYECVLKRKEQQAAEQISKMMEL AREKQAAELKALKETAEIDTKEMKKKLETKRLERIQGMTKVTVDKMAQERLKREINNSHI QEVVQVIKQMTENLEKHQEKLEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKE LVRACFRTCFPSETKDKPERDCECPPELCEQDPVIAKADVQESRL NT seq 3558 nt NT seq  +upstreamnt  +downstreamnt atgtctctgctcaaccctgtgctgctgccccccagggtgaaggcctatctgagccaaggg gagcgcttcatcaaatgggatgatgaaactacaattgcctctccggttatcctccgtgtg gatcctaagggctactacttatactggacatatcaaagcaaggagatggagtttctggat atcaccagcatccgggacactcgctttgggaagtttgccaagatgcccaagagccagaag ctccgggacgtcttcaacatggactttcctgacaacagcttcctgctgaagacactcacc gtggtgtctggcccggacatggtggacctcaccttccacaacttcgtctcctacaaggag aacgtgggcaaggtctgggctgaggacatactggccctagtcaagcatccgctgacggcc aacgcctcccgcagcaccttcctggacaagatcctcgtgaagctcaagatgcagctcaac tctgaagggaagattccagtgaagaactttttccagatgtttcctgctgaccgcaagcgg gtggaagctgctctcagtgcctgccacctccctaaaggcaagaatgacgccatcaatcct gaggacttcccagaacctgtctacaagagtttcctcatgagcctctgtcctcggccagaa atagatgagatcttcacttcttaccatgctaaggccaaaccctacatgacgaaggagcac ctgaccaaattcatcaaccagaaacagcgggactcccggcttaactccctgctgttcccg ccagcacagcctgaccaggtgcagggcctcatcgacaagtatgagcccagtggcatcaat gtgcagaggggccagttgtcacctgagggcatggtctggtttctctctgggccggagaac agtgtgctggcccaggacaagctgctgctccaccacgacatgacacagccactcaatcat tacttcatcaactcgtcccacaacacctacctgacagctggccagttctcaggcctctcc tcggctgagatgtaccgccaggtgctgctgtccggctgccgttgcgtggagctagactgc tggaaggggaaaccccctgacgaagagcccattatcacccacggcttcaccatgaccaca gacatcttcttcaaagaagcaattgaggctattgcagaaagcgcctttaagacctccccg tatcctatcatcctgtcgtttgagaaccatgtggactcaccccgccagcaggctaagatg gctgagtattgccggacgatctttggggatatgctgctcacagagcccctggaaaagttc ccactgaaaccaggtgtccccctgcccagccctgaggatctcaggggcaagatcctcatc aagaacaagaagaaccagttttccagccccacctcctccagtaaggatcctggtggggag gctgagggcagcagcccacgcagtgcccctgcaggtgagggcacagtgtgggctggcgag gaagggactgagctggaggacgaggaggtggaagaggaagaggaggaggagtcaggaaac ctggacgaagaagagattaagaagatgcagtcggatgagggcacagcgggcctagaagtg acagcttatgaggagatgtccagcctagtcaattacattcagcccaccaagttcatctcc tttgagttctctgctcaaaagaaccgaagttatgtcatctcatccttcacagaactcaag gcatatgacctgctctccaaggcctcggtgcagtttgtggactacaacaagcgccagatg agccgcatttaccccaagggaacccgtatggactcctccaactacatgccccagatgttc tggaatgctggatgccagatggttgccctcaacttccagacgatggacttgcccatgcag cagaacatggcagtgtttgagttcaatgggcagagcggctacctcctcaagcacgagttc atgcgccggccagacaagcagttcaaccccttctcagtggaccgcatcgatgtggtggtg gccaccaccctttctatcacggtgatctctgggcagttcctgtcagaacgcagcgtgcgc acctatgtggaagtggagctgtttggccttcctggggaccccaagaggcgctaccgaact aagctgtcacccagtaccaattccatcaatcctgtctggaaggaggagccctttgtcttt gaaaagatcttgatgcctgagctggcctctctcagggtggctgtgatggaggaaggcaac aagtttcttggacaccgcatcatccccatcaatgccctaaattctgggtaccaccacctg tgcctacacagtgagagcaacatgcccctcaccatgcctgcgctcttcgtcttcctggag atgaaggactacgtacctggtgcctgggcagatctcactgtggccctcgccaaccccatc aagttcttcaatgcccatgacaagaggtcggtgaagctcaaggaggtcatgggagggctg cctgagaagcccttcccactggcgagtccagttgccagccaggtcaatggtgcgttggcc ccaaggagcaatgggtcaccagcagccagggcctgggccggggaagaggctataaaagaa gttgcggagccacggaccgccagcctggaggagctccgggagctaaagggcgtcgtgaag ctgcagcggcggcacgagaaggagctgcgggagttggagcggcgcggagcgcggcgctgg gaggagctgctgcagcggggcgcggcgcagctggccgagctcgggccacggggcgctggg ggtggcggggccggcaagctcggcccgggcaaaggctctcgcaagaagaggagcctgcct tgcgaggagagcgccggagccgcgccgggcgagggccctgagggcatggacgcgcgcgtg cgggagctgaaggacaggctggagctagagctgctgcggcagggcgaggagcagtacgag tgcgttctgaagcgcaaggagcagcaagcggccgagcaaatctccaaaatgatggagctg gccagagagaaacaggcggcagagctgaaggccctgaaggagacggcggagatcgacacc aaagagatgaagaaaaagctggagaccaagagactggagcggatccagggcatgaccaaa gtcactgtagataagatggcccaggagaggttgaagagagagattaacaattcccacatc caggaagtagtgcaggtgatcaagcagatgacagagaacttggagaagcaccaggagaag ctggaagagaagcaggctgcttgcctggaacagatacgggagatggaaaagcagttccag aaggaggcgctggcagaatacgaggccaggatgaagggtctggaggcagaggtgaaggag ttggtgagggcctgcttcaggacctgctttccctctgagaccaaggacaagcctgagagg gactgcgagtgccccccagagctgtgtgagcaggacccagtcatagcaaaggcagatgtc caggagagccgcctttga

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