KEGG   Cololabis saira (Pacific saury): 133419771
Entry
133419771         CDS       T09849                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
csai  Cololabis saira (Pacific saury)
Pathway
csai04010  MAPK signaling pathway
csai04012  ErbB signaling pathway
csai04020  Calcium signaling pathway
csai04510  Focal adhesion
csai04520  Adherens junction
csai04530  Tight junction
Brite
KEGG Orthology (KO) [BR:csai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    133419771 (erbb2)
   04012 ErbB signaling pathway
    133419771 (erbb2)
   04020 Calcium signaling pathway
    133419771 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    133419771 (erbb2)
   04520 Adherens junction
    133419771 (erbb2)
   04530 Tight junction
    133419771 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:csai01001]
    133419771 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:csai04147]
    133419771 (erbb2)
   04090 CD molecules [BR:csai04090]
    133419771 (erbb2)
Enzymes [BR:csai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     133419771 (erbb2)
Protein kinases [BR:csai01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   133419771 (erbb2)
Exosome [BR:csai04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   133419771 (erbb2)
CD molecules [BR:csai04090]
 Proteins
  133419771 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Tcell_CD4_C Haspin_kinase DUF5091
Other DBs
NCBI-GeneID: 133419771
NCBI-ProteinID: XP_061565170
LinkDB
Position
19:10902846..10949330
AA seq 1292 aa
MEAVRSLVFLGAALLGAAAAREVCLGTDMKLVLPSSLENHYETLKLLYTGCQVVHGNLEI
THLHGSPDLSFLQEIVEVQGYVLVAHVSVSVVPLDNLRIIRGSQLYNSSYALAVLDNTLA
NKGLRTLRLRSLTEILLGGVYIQGNPQLCFPDPGKIAWMDTLDEQNIHSSQLHLQPRATN
CPTCHPLCGKSCWGETELDCQTLTRSNCTSGCQRCKGPLPNDCCHRQCAAGCTGPKDSDC
LACRHFNDSGVCKENCPPPTIYDPVTFQTKPNPNKKFNFGATCVKTCPYNYLAMEVACTL
VCPRANQEVIITQPDGTETQKCEKCEGDCPKVCYGLGMDNLGVMDNHGVTMVTSSNVEQF
NKCKKIFGSLAFRPQSFARNPATNTSGLTLEQLKAFQKLEEITGYLYIDAWPEEWTNITV
FENLKVIRGRMLYMGVFSLAVQKLHIHSLGMRSLRSVSGGLVLLYNNSQLCYTDSLPWGN
LLHPTQGPHRIVSRNQNSEVCEREGHVCHSLCQGGCWGPGPSQCVSCKSYQRGSECVEQC
DIYQGSVREYVDGSTCLACHAECRPLNGSASCHGAGAEDCTECRNFQDGNFCVDHCPSGV
KEDHHTVWKYSNATGHCLPCNSNCSLSCTVMDERGCPIDTRTGPGTTIAAAVGGVVLFFI
LVALLIFYLRRQRTLKRKATMRRYLQEQELVEPLTPSGASPNKAQMRILKETELKKLRVL
GAGAFGTVHKGVWAPEGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVTSPYVCRLL
GICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEDIRLVHRDL
AARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSDVW
SYGVTVWELMTFGSKPYDTIPARDIPDVLEGGERLPQPPICTIDIYMIMVKCWMINPDSR
PKFKDLVLDFSAMARDPPRYLVIKNDEQMSTCSPVDSTFYRMLLEDGDNMGEMMDAEEYL
VPQPNLFPRTEPQANGPSRHHSYRQSRDHSLDVEPFITGGARSTHSSMSTLGRSQYPTSS
FGVTTANGFLPQYPTLARSMSGQSDSVFLDPVPDSVSPASPGRYCKDPTYPDGSQDDLET
DGPNGFHHPHHPHHLHHSLPRRSHGHNHNHALPEYVNQEIEDLRPAVPERPTTLPRKGCR
VDRRLPNGLSSGHSVENQGYLIPVNSTSPAFDNPYYLDLVAKATAAPESAAADGAAALES
DGGAPRHVNGFVTPTAENPEYLGLADTWSGHT
NT seq 3879 nt   +upstreamnt  +downstreamnt
atggaggcggtgaggagtttggtgttcctgggagccgcgctgctcggagccgccgcggcc
agagaagtctgcctgggtacggacatgaaactggttctgccctccagtctggaaaatcac
tatgagacgctgaagctactctacaccggctgccaggttgtccatggcaacctggagatt
acgcatctccatggaagccctgacctctctttcctacaggaaattgtggaggttcagggt
tacgtacttgttgcacatgtctcggtgagtgtggtgcctctggacaaccttcggatcata
agaggcagccagctgtacaactccagctatgcgctggctgtgctggataacactttggcc
aataaaggactacggaccctccggctgaggagcctcacagagatcctgttgggtggggtg
tatattcaggggaacccccagttgtgcttcccggatcctgggaaaatagcttggatggac
acattagacgagcagaatatccactccagtcagctgcacctgcagcctcgggccactaat
tgtccaacttgtcaccctttatgtgggaaaagctgctggggagaaactgaactagactgc
cagacattgacccgaagtaactgcacgtcgggctgtcagcggtgtaaaggtcctctgccc
aacgactgctgccaccggcagtgtgctgctggctgcaccggacccaaagactcagactgc
ctggcctgccgtcacttcaacgacagtggtgtttgtaaggagaactgtcctcctcctacc
atttatgaccctgtcacttttcagaccaaacccaacccaaacaaaaagttcaactttgga
gccacgtgcgtcaagacgtgcccctataactatcttgctatggaagtggcctgtactttg
gtatgtccacgagccaaccaggaagttattatcacccagcctgatggaactgagacacag
aaatgtgaaaagtgtgaaggagactgtccaaaagtgtgttatggtctgggtatggacaac
ctcggcgtcatggacaatcatggcgttaccatggtaacatcttctaacgtggagcagttc
aacaagtgtaagaagatttttgggagtcttgctttccgcccacagagctttgcaaggaac
cctgcgaccaacacatctggcctgactttggagcagctgaaggctttccagaaacttgaa
gaaataacaggttatttgtacattgatgcctggccagaagagtggactaacattactgtc
tttgaaaacctgaaggtgatcaggggcaggatgctctacatgggagtgttttcgctggcc
gtccagaaactacacatccattctcttggaatgcgttcgctacgcagcgtcagtggaggt
ttagtgttgttgtacaacaattcacagttgtgttacactgattcgctgccctgggggaat
cttctccatcccacccagggcccccatcgtatcgtcagccgcaaccaaaactctgaagtc
tgtgagagagaggggcatgtttgtcactcactgtgccagggaggctgttggggtccaggg
cccagccagtgtgtgtcctgcaagtcttaccagcgtggctctgagtgtgtagagcaatgt
gacatctatcaggggtctgtgcgtgaatacgtagatggatctacttgccttgcctgtcat
gcggagtgtcggcctctcaatggttcagcctcctgtcacggcgcgggtgcagaagattgc
actgagtgcagaaacttccaagatggaaatttctgcgtggatcactgtcccagcggtgtg
aaagaagaccatcacactgtgtggaagtacagcaacgctacaggacactgtctgccctgc
aacagtaactgctcactatcctgcactgtgatggatgagagaggctgccccattgatacc
aggacaggacctggtacaactattgctgctgctgtgggtggagtagtgctcttcttcatc
ctggtggctctgctgatcttttacttgaggagacagaggacactgaagaggaaggcgacc
atgaggaggtacctgcaggaacaagagctggtggagcctttaacaccgagtggtgcctct
ccgaataaagctcagatgcgtatcctaaaagagactgagctgaaaaaactccgggttctg
ggtgcaggggcctttgggactgttcacaagggggtgtgggctcctgaaggggaaaatgtg
aaaataccagtggccattaaggtgttgcgggagaacacctcaccaaaggccaataaagaa
atcctggacgaagcatatgtgatggcaggggtcaccagcccctatgtgtgtcgcctcctg
gggatctgcctgacctccacggtgcagctggtcacccagctgatgccgtacggctgcctc
ctcgactatgtcagggagaataaggaccgcattggttcacagtttctcctcaactggtgt
gtccagatcgccaagggaatgagttatttggaagacatccggttggtgcacagagatctg
gctgcccgcaatgttttggtgaagaacccgaaccacgtgaagattacagactttggtctg
gcccgcctgctcgatatagacgagaccgagtaccacgctgacggagggaaggtgccaatt
aaatggatggctttagagtctattttgcacaggaaatttactcatcagagtgacgtctgg
agctatggagtgactgtttgggagctgatgacatttggatctaagccctacgacacaatc
ccagcgagagacatcccagatgttttagaggggggagagcggctcccccagccccccatc
tgcaccatcgacatctacatgataatggtcaaatgctggatgattaatccggacagcagg
ccgaagttcaaagatctggtcctcgacttcagtgccatggccagagatccaccgcgctac
ttagtcattaagaacgacgagcagatgagcacatgcagcccggtggacagcaccttctac
cggatgcttcttgaggacggggacaacatgggggagatgatggatgctgaggagtatctg
gtgccgcagccaaacctcttcccaaggacggagcctcaggccaacgggccgtccaggcac
cactcgtacaggcagagcagagatcatagcctagatgtggagcccttcatcactggtggc
gctcggagcacgcactcatccatgagtactctcggccgcagccagtaccctacctcatct
tttggagtcaccaccgctaatggctttttgccgcagtacccgacgctggctcgcagcatg
tcaggccagtccgactccgtcttcctggatccagttccagactctgtctccccagccagc
cctggacgctactgcaaagatcccacctaccccgacgggagccaggatgacctagagact
gacgggccaaatggctttcatcatcctcatcatcctcatcaccttcatcactcgctgccc
agacggagtcacggccataatcacaatcacgccttaccagagtacgtgaaccaggagatt
gaagatctcaggccggcggtccctgaacgacccaccacgcttccccgtaagggctgcaga
gtggacagacgtctccccaacggtctcagttcaggtcacagtgtggaaaaccagggttac
ctgatccccgttaactccacctctcctgcctttgacaacccgtactacctggacctcgtg
gccaaagccacagctgcacccgagtctgccgcggcggacggtgctgcagccctggagagc
gatggcggagctcccaggcacgtgaacgggtttgtgactcccactgcagaaaacccagag
tatctgggactagcggacacctggagcgggcacacttga

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