Cololabis saira (Pacific saury): 133423739 Help Entry 133423739         CDS       T09849                                  Symbol sspo Name (RefSeq) SCO-spondin   KO K24434   SCO-spondin Organism csai  Cololabis saira (Pacific saury) Brite KEGG Orthology (KO) [BR:csai00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:csai04990]     133423739 (sspo) Domain-containing proteins not elsewhere classified [BR:csai04990]  Thrombospondin domain-containing proteins   Other thrombospondin domain-containing proteins    133423739 (sspo) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TSP_1 TSP1_spondin VWD Ldl_recept_a TIL F5_F8_type_C VWF TSP1_CFP_C TSP1_ADAMTS VWC Pacifastin_I F5_F8_type_C_2 TSP1_CCN FnI_RECK Motif Other DBs NCBI-GeneID:  133423739 NCBI-ProteinID:  XP_061570036 LinkDB All DBs Position 22:complement(5231570..5420357) Genome browser AA seq 5694 aa AA seqDB search MWGIMETVVVMVLAVQAVLGAGRWCEHEVEEQVERVLSPRLQLEASCSAVYQYNVQGWRL DVDRMRVRHGGDDGIALYYKQQGPKATCLLYKPPEMEREMVNRTVRACCEGWAGPRCSQG VGLGFRGQCYSTWSCEEFPGVHNSSLMSMEQCCSTMWGLTWRNVSDQTCLSCTYTLLPDA QSSPVVRSGLLGTARVPQSSATCMSWGGAHYRTFDRKHFHFQGSCTYLLASSTDGTWAVY ISTVCDGGGECSKALRMMLGLDLVSIHKRNLTLNNRPVAGESLFQNGVSLHWLGDFVFVE SGLGLRLKFDLLNTVYLTVTAEHLGATRGLCGLYNSNPNDDFTTLGGSVSMYAASFGNSW RVPDQHNEGCSDAAELGHSCDVAGDAALRRRAESVCQQLSENPFTHCHLRVDPAAYMDTC LYLYCSLAPADRQGAVCDTLASYARECAQQNVIVVWRTDKLCGRVCPRGQVFSDCVSSCP PSCSSPQPAGPSAGPGRCSEECVGGCECPPGLYLHQGACLQRDRCPCFHRRRSHRPGDTI QHRCNTCVCRAGQWQCTGEKCAGQCTLIGALRVTTFDKKRYSLQGGDCPFIAVEDFVDRK LVVAVRCGECPAGGRGGGGEQGCLKEVLVTVLHTTVRVTDTGAVTLNGQREALPVMTGDL VVRRASSSFLLIQTFGAQILWYLDGPFALISLQPGFANKVRGLCGTLTWSQHDDFTTPEG DVENSVTSFVEKFTTERCSLPRGLQPDPCSTYTQRRSYAETLCAIIHSPVFQVCHDVVER EPYFHLCLSEVCGCAQKSCHCTILTAYAQHCAQEGAVVQWRNQTFCPVQCSGGQVFQECG RACGGSCSDLQKTWSCMDAGSDSICVPGCQCPAELVQDHRGQCVPSALCPCVQGDQMYSP GASLQNNCNTCVCERGQFNCTQKRCEGVQRCPGSLVYSPHSCLLSCSGLDPPGHQQASGG TQSCREPLSGCVCPQGTVLLGDGCVLPEECPCHHNGRLYYSNDTITKDCNTCVCKQRRWH CTQAVCAGVCVATGDPHYVTFDGRCFSFLGDCQYVLARESSGLFSVTAENVPCGSTGVTC TKSVTLSLGHTVIHLLRGKAVTVNGMPVTLPKSYSGSGLIVERVGLFVSLSSRLGVTLLW DGGMRVYVHLAAHLRGRVGGLCGNFDGDTENDFTTRQGIVESTAELFGNSWKVSPSCPDV ANQDLRDPCALSPHRVPWARRRCSVLTQDLFSQCHADVPFQQYYSWCVFDACGCDSGGDC ECLCTAIASYAEECNRRGIYIRWRSQELCPLQCERGLVYDPCGPACSLSCPSDQQSPYSQ CGVLSCVEGCFCPAGTVQHGGGCVSPAECPCAWDGSMFPPGTTITQHCQNCSCEEGVWQC EGVSCPPPPPPCLESEFPCAAGRCIPSQWACDNQDDCGDGSDEVCPSTCSPDQFRCAGTP SGPCLNLALRCDGHPDCADQSDEEFCGPPTPVPLCPPGEFQCANGKCLAASRVCDGRLDC GFADASDEQDCGVVCDEGEFLCPGGRCILYLHRCDGHDDCGDLSDERGCVCAAGEFQCPG DQCVPAERVCDGHRDCRSGTDEAVCPRKVTCAPDQFACGDGTCVPTSKLCDGAADCPGRE DEDRPGCSTGVVTPPVTPSTACRSYEFSCATGGQCVPRAWRCDGETDCMDGSDEQRCAAP CRSGQVPCFSGDQCVDYQQLCDGIPHCRDASDENIDNCGSTMIPPCPGSFPCDNRTCVNM SQVCNGIPNCPRGDDELVCDKTVSPQPPGGRNTTCFEHTCLDGTCIPFNSVCNGLPDCPD SSLTPIGGPTDEQGCRTWSSWGPWTPCSTSCGTGSMSRERSCPPGDPLRHCSGHSVQRQQ CFNTTCPVDGRWLPWGSWSNCSSACGGVQVRHRGCSPPHYGGRDCLQLAGPSNLSMEIKR CPEDGCVNVSCPPGLERRSCAPCPVSCAHVSSGAPCDPPSSCSSGCWCPDGQVMSHAQRC VWPGECPCDVSGVRYWPGQQVKVDCQVCVCERGKPQRCRPNLDCSVHCGWSSWSGWGDCL GPCGVQSVQWSFRSPNNPSRHGDGRLCRGIYRKARRCQTAPCDECEYQGRSHAVGDRWRS ERCRFCHCLPNLTVQCSLYCPYAVSGCPEGLKLVPGEADRCCYCQGENATESVTTSPDRV TSKPAGGSTPLVPTYPLPPEDECWAPLGVQTLPASSFTASSQQAGHPPEAARLHGWDMHR DLQGWSPEPEEYKDLPQRRPEGHAGDTRSPYIQVDLLKPYNITGVLTQGGGAFSTFVSSF SLQFSPDGHRWHTYKELVSDARPRAKVFLANSDDGGVAENRLDRMVSARFVRLLPHDFKN GIYLRLEVMGCGDGSRWSTPTPPSPVSPVSPGGCREKEFSCGNGRCVPAGPLGVVCDGVN DCGDGSDEMHCGTQPSSTAPSPRCPPGQFSCPPPGGCIDAGLRCDGIPHCPRGEDESGCH PHDATTPSVRPHTPTPSPLKTPSTAAVTSPAEAPTDGSPGYHGVCASPLGLEDGRIRYGQ LTSSSHRENSPADAGRLNIVPNIQVMEPGWSPKPTDPQPYFQVDFLEPAWISGLVTQGSE RMWGYLTKYRLSFALHSSLFTNYTENRKPGGPNKVFEVRMVGRKPVTRWLGRLVRARYMR IIPVEFRHPFHLRVEVLGCRGDELVTPSSETTAAHRCPTGQVPCQHSEECVLVSVLCDGR PDCTDHSDETGCGTTGSPGLLTTRSQGGFPGVATPGVTGPTTPSVYPGVTTGHPGLHLRT SVRPGKPGLQTTEAPSVTATSPDGGLPRVLCVQGQFACRSFGCVDSAQVCDGGRDCLDGS DEERCGTTAGPPATSRLPPVPPVPSPCSSKQFSCESGECIQMSRRCNLHRDCADGSDEKH CVDCIMSPWTAWSSCSVTCGLGSLFRQRDILRDALPGGSCGGAQFDSRACFLKACPVNGH WSEWTEWSQCDAPCGGGVRQRIRTCSAPPPKNGGRDCEGMTQQSHSCNMQSCTNETGTQT GCVHGMVLVTRDDCQAGRVEPCPPMCSDVSMTSNCTAACIVGCRCPPGLFLQEGRCVNAS RCLCQWEGEPLQPGQVIRRNPCSTCVCKEGNVTCDTSKCRAACHWSAWSSWSPCDVTCGV GLQQRYRSAVNPAGAVQPCPGDSSEARRCFHQCLPGLPDGAWSKWTVWSECSKTCFSHVN DVGIRRRFRGCDHTHNQSLCHGDSEEQEPCNTVHCPVHGGWSAWSAWSECSTDCDSGVQT RERFCSLPAPQHGGHSCTGPHIQTRDCNSHPCSGVCPEGMTYMTVAECRAQGGACPRVCL DMTPAEVQCATTCYDGCYCGPGFYLFNSSCVPLARCPCYHRGEMYPASTRLPVDACNNCT CTNGEMECGAAPCPVDCGWSTWTGWSDCSRTCDVGVRRRYRSGTNPLPAYGGQPCEGQRV GIDTCSIEPCLGTKEPWSGWSECSVTCGGGYRTRTRGPIRIHGTAQQFSACNLQPCGGSR ACPPGLEWKQCVAGAVSCLDITMELSRNCTAGCQCPPGTVLQDGVCVPESNCRCDVDGVQ YNPGDTVSRKCSNCTCEGGRLVNCSQFSCNSDGQWSGWTPWGQCSVSCGAGLQSRYRFCS TRQQQSSSAPSCVGPHREDQVCVGGPCDRDGGWSQWSNWTDCTKSCGGGMRSRRRSCDSP APEGEGNYCEGLGTKVLSCNTDHCPVAPCSQVPGTAFSSCGPSCPRSCDDLAHCEWLCEP GCYCTEGKVLSANGTACVQREDCPCLDLNTGRRLEPAEITQAPDGCNNCTCHSGRFNCTR KLCPVSGGWCRWSDWTPCSRTCGAESVSRYRSCSCPEPKAGGETCPGEQELHSGTGVQIQ RQPCPVTTFCPVHGSWSSWSAWSECDGCTGSSTRTRECNSPPARFGGLPCLGEGRQSRGC HDNITVCSDCGASQQEWPCGKPCPRDCSDLHGDAECLDSLECSQTCGCQGDMVLQDGVCV GQDECRCKYYNGSTAGGLDPSNSSWVWPGRSDWQFANPGDNIISDCRNCSCEAGVMHCQS VPGCHVDGAWGQWGSWTKCSLSCGGGMKFRKRLCNNPTPQSGGRGCLGDSDQQRGCNTQQ CADPGGPWLPWSPWSQCSVSCGGGQQSRSRLCSSPCHGLSRQSKTCNTQVCFDVGCPPGR LYRECERGEDCPFNCAQVSGREGCYSDGCEEGCHCPPHTYQHRGVCLPECPCLVDEEFLA SLQSVSVTPVSSLLLHNVSEGAELQSGDTVVHECSSCSCEHGRWNCSLEHCPVDGGLSPW GPWSPCSLSCGGLGVRSRFRGCTKPAPAHGGRDCQGPRQETTFCQAPDCPAVVPTEEPPT PEEDSGFSPWSVWSPCTKTCTDVQNPARKSRRRHCIKPPCSGSPREEKACNLPQCPGDIC VSTDCARRNCSWTEWGEWSPCSRSCGVGQQQRIRTFLRPGSNGSWCEDIIGGNLEHQFCN IAPCKVDGGWSRWSPWSHCDKRCGGGRSIRTRSCSSPPPKNGGRRCEGEKNQVKPCNTKA CGEKGCPPGQEFVQCANQCPQRCSDLQQGIECQGHAECQPGCRCPTGQLQQDGACVQLWQ CDCVDALGHTWAAGSRHQVDCNNCSCADGQLVCTNHSCQMSCTWSSWSSWAPCSVSCGQG QRSRYRSLIPETEETICHFEEVQQKSCEPGACPPLCLLDERELGVGDTWLQGECKQCTCT PEGVYCQDVDCRVDGGWTPWSVWSDCSVTCGQGAHVRTRACINPPPRNNGSSCSGPERET QHCQTPLCLDDLCPWLPWSPCSQSCGAGTLSRRRKCMCEEGGDVACPPEVEAERNREETQ LCYKRPCPACPMSAWSVWSRCSCQSQRQQRYRVALVPATRGQQCSPVETQSRTCTLSPCD ACDAPFVYSACGAPCEKQCALLAGGDLCSDTRECSPGCYCPEGLLQLNGSCVPPDECGCT FVQHGAPGQPPKPVVVAQGATVTIGCSSCLCHNGSLHCDSRECEVVLSEWSEWTPCSPCV PASSEPLAALLETAGGSRMVSIQKRFRACLDIDSGLPTAREEESRCPGLLVEQRLCPDVN ICRDLCDWSVWSSWTACADPCSGGVRQRFRQPRASPPGPRCKSQQTQSQSCNTGLCPGER CEDRERTYQETCANRCPRSCADLWEHVQCLQGACHSGCRCPEGQLLQDSRCVPVAECRCG LPSGNGTLQFQPKEEVTVDCNTCVCEGGVLVCTRRPCPVYEAWSSWSPCSVSCGRGQTTR TRSCRDAVGGPPCAETTQTQGCDLPSCPAGCLLGQWSAWSECSATCGGGVSLRNKTVLRE PEPGGAACPGPLEQHTICSTQSCLPECPSGQVYTNCSGSCPYSCEDLWPHTQCLLGPCTP GCKCPPGQVWYKGACVDPADCPCSSLSLPAEYQRWNATTGGLTDVLLQPGTTVQHLCNTC VCRAGAFRCSAEPCHVDCQWSGWSPWRPCSASCGSGQQSSARSVLQPSRYGGAPCDGPAL RTTGCTAPDCACPAGERWRRSVSEETPLCERSCQDIYSSPPVNCSRAAEGCVCQEGLYRN PAGGCVIPALCPCLDQGVLREAASEWDEGCLSCSCVNGRKRCQTRCPPLYCDEGEVKVEE PGSCCPVCRKQFPDEPVPECRRYVRAQNITKGDCRLDNVEVSFCRGRCLSRTDVILEEPY LRSECECCSYRLDQDNPVRFLSLQCESGESEPVVLPVIHSCECTSCQGGDLSRR NT seq 17085 nt NT seq  +upstreamnt  +downstreamnt atgtgggggatcatggagacggtggttgtgatggtgctggctgtgcaggccgtgctggga gcggggcgctggtgtgaacacgaggtggaggagcaggtggagcgcgtcctctctccacgc ctgcagctcgaggccagctgctctgccgtgtatcagtacaacgtccagggctggaggctg gacgtggaccggatgcgtgtccggcatgggggcgacgacggcatcgcactgtattacaaa caacaggggccaaaggcaacctgtctcttgtacaaacccccggagatggagagggagatg gtgaacaggacggtgagagcgtgttgtgagggctgggctggacctcgctgctctcagggt gtgggtttgggctttcgtggtcaatgctactccacatggagctgtgaggaatttcctgga gttcacaattcctccctgatgtccatggagcagtgctgcagcaccatgtggggactgacc tggaggaacgtctccgaccagacctgcctgtcctgcacctacactctcctgccagatgcc cagtcttctcctgtggtgcgtagtggtctgctgggcactgccagggtcccccagagctcc gccacctgcatgtcctgggggggagcccactaccgcacctttgacaggaagcacttccac ttccagggcagctgcacctacctgctggcttcatccaccgacgggacctgggctgtgtac atcagcacggtctgtgatggaggaggggaatgcagtaaggcactgaggatgatgctgggc ctagatttggtttcaattcataaaaggaacttaactctaaacaaccgtcctgttgctggg gaatcgctgtttcaaaatggggtcagcctgcactggctcggggacttcgtcttcgtggag agcggcctgggcctcaggctgaagttcgacctgctcaacactgtgtacctgacggtgacg gccgagcacctgggggccaccagggggctctgcggcctctacaacagcaaccccaacgat gatttcaccactctgggagggagcgtgtccatgtacgcggccagcttcggaaattcctgg agagtcccggaccagcataacgagggctgcagcgatgcggcggagctcggccacagctgt gacgtcgccggcgatgccgctcttcgcaggcgggcagaatccgtctgccagcagctttcg gagaatcctttcacacattgccacctccgggtggacccggctgcctacatggacacctgt ctgtacctgtactgcagcctggcccccgcggaccggcagggtgctgtgtgtgacaccctg gccagctacgcccgcgagtgtgcccagcagaacgtcatcgtggtgtggaggacagacaaa ctctgtggtcgcgtctgtcccagaggtcaggtgttctccgactgcgtgtcctcctgtcct cccagctgctcctccccccagccagcagggccgtcggcgggcccggggcggtgcagcgag gagtgtgtggggggctgcgagtgcccccccggcctctacctgcaccagggcgcctgtctg cagagagaccgctgtccctgcttccaccgcagacgcagccaccggcccggggacaccatc caacaccgatgcaacacctgtgtgtgcagagcaggccagtggcagtgcacgggggagaag tgtgcaggacagtgcacgctgattggggcgttacgggtgaccacctttgacaagaagagg tattccctgcaggggggggactgccccttcatcgctgtggaggactttgtggacaggaag ctggtggtggccgtgcgctgtggagagtgtccggcaggaggacgaggaggcggcggagag cagggctgtctgaaggaggtgctggtcacggtgctccacaccacagtcagagttacagac acgggtgcagtgaccttgaacggccagagggaggcgctgcccgtaatgacaggggacctg gttgtccgcagggcctcgtcttcattcctcctcatccaaaccttcggagcccagatactc tggtacctagacggaccctttgccctcatcagccttcagcctggatttgctaacaaggtg cgtggtctgtgtgggaccctgacctggagccagcacgacgacttcaccaccccggaagga gacgtggagaacagtgtgacatcttttgtggagaagttcacgacggagcgctgcagcctg cccagagggctgcagcctgacccctgctccacctacacccagagacggagctacgcagag acgctctgcgccatcatacacagccctgtctttcaggtgtgtcatgacgtggtggagagg gagccctatttccacctgtgcctgtcagaagtgtgtggctgtgctcagaagtcttgccac tgcactatactcaccgcttacgcccaacactgtgctcaggaaggagcagtggtccagtgg cgcaaccagaccttctgcccggtccagtgttcggggggtcaggtgtttcaggaatgtggt cgtgcctgcgggggctcctgctcagacctgcagaagacctggagctgcatggatgccggt agcgacagcatttgtgttccgggttgccagtgtccagcagaactggtgcaggaccaccgg ggccagtgcgtgcccagcgctctgtgcccgtgtgtgcaaggagaccagatgtactcacct ggggcttcacttcagaacaactgcaacacctgcgtgtgcgaacggggacagttcaactgc actcagaagcgctgtgagggtgtgcagcgatgtccgggctctttggtctactccccacac tcctgcctgctcagctgctccggcctggacccccccggtcaccagcaggcgtccggcggg actcagtcctgcagagagccgctgtctggctgcgtctgccctcagggaacagtcttactg ggtgatggctgtgtgctgccggaggaatgtccgtgtcaccacaacggtcggctttactac agcaacgacaccatcactaaagactgcaacacctgtgtgtgcaagcagcgccgctggcac tgcacccaggccgtctgcgccggggtgtgcgtggccaccggcgacccccactacgtcacg ttcgacggccgctgcttctccttcctgggcgactgccagtacgtgctggccagagagagc agcggcctgttcagcgtcacggcggagaacgtgccctgcgggagcaccggggtcacctgc accaagtcagtcaccctcagcctgggacacaccgtcatccacttgctgagaggtaaagct gtaactgtcaacgggatgccggttaccctcccaaagtcctacagcggcagcggcctcatt gtggagagggtgggcttgttcgtctctctttcttcccgactcggagtcacgttgctgtgg gacggaggtatgcgcgtgtacgttcacctggcagcccatctgcggggcagggtcgggggg ctgtgcggcaactttgacggagacaccgagaacgacttcacaacgcggcagggcatcgtg gagtccaccgctgagctttttgggaattcctggaaggtcagtccctcctgccccgatgtg gcgaaccaggacctccgagatccctgcgctctgagcccccacagggtgccgtgggcccgg aggagatgctccgtcctcacgcaggacctgttctcccagtgccacgccgacgtgcccttc cagcagtactacagctggtgtgtctttgacgcttgtggctgcgactcgggaggcgactgt gaatgtctgtgcacagccatcgcgtcctacgccgaggagtgcaaccggcgagggatttac atccgctggaggtcccaggagctctgtcccctgcagtgtgagagagggctggtgtacgac ccgtgcggcccggcctgctctctgtcgtgtcccagtgatcagcagagtccttattctcag tgtggcgtgctgtcgtgtgtggagggctgcttctgccccgccggcaccgtccaacatggc ggcggctgcgtgtcgcctgcagagtgtccgtgtgcgtgggacggctccatgttccccccc ggaaccaccatcacccagcactgccagaactgctcctgtgaggagggtgtgtggcagtgt gagggcgtgtcctgccctccgcccccccctccctgtctggagtcagagttcccctgcgcc gccggccgttgcatcccctctcagtgggcgtgtgacaaccaggacgactgcggggacggc tcagacgaggtctgtccgtccacctgctccccggaccagttccgctgcgccggcacgccc agtggaccatgtttgaacctggctctgcgttgtgatggccacccagactgtgctgaccaa tcggacgaggagttctgcggaccccccacgcccgtgcccctgtgcccacccggcgagttt cagtgtgcaaacggaaagtgcctggcagccagccgcgtctgtgacggacggctggactgc ggctttgccgatgcgtctgatgagcaagactgtggtgtggtgtgtgatgagggggagttt ctgtgtccgggaggacgctgtattctctacttgcaccggtgcgacggccacgatgactgc ggagacctcagcgacgagagagggtgtgtctgtgcagcgggggagttccagtgtcccggc gaccagtgcgtccctgcagagcgagtgtgtgacggacacagagactgccgttcagggacg gatgaagcagtctgtccacgtaaagtgacctgtgcccccgaccagtttgcctgcggtgac ggcacctgtgtccccacaagcaagctgtgtgacggagcggctgactgtccgggccgggag gacgaggaccgacccggctgctccaccggggtcgtgaccccgccggtcactcccagcaca gcctgcaggtcgtatgagttcagctgtgccaccgggggacagtgcgtgcctcgggcctgg cggtgcgatggggagacagactgcatggatggcagtgacgagcagcggtgtgctgccccg tgccgctctggccaggtgccttgcttcagcggggatcagtgcgtggattaccagcagctt tgtgatggtatcccgcactgcagagatgcctcggatgagaacattgacaactgtggctcg accatgatccctccctgtccgggcagcttcccgtgtgacaaccgcacttgtgtgaacatg tcacaagtctgcaacggcatccccaactgtccacggggcgacgatgagctggtgtgtgat aaaacggtgtcaccgcagccccctggcggcaggaacaccacctgctttgagcacacctgc ctggatgggacctgtattccctttaactcggtgtgcaacggtttgccagactgtccggac tcctccctgacacctattggaggacccacggatgagcagggctgcaggacctggagctcc tgggggccctggaccccctgcagtacctcctgcgggactggttccatgagccgggagagg tcctgccccccaggggacccgctgcgccactgcagcggccacagcgtccagaggcagcag tgcttcaacaccacctgccctgtggacggccggtggcttccctggggcagctggtccaac tgttccagtgcttgtggcggggtgcaggtgaggcacaggggctgctcccccccgcactac gggggccgggactgtcttcagctcgctggaccatccaatctctccatggagatcaaacgg tgtcctgaagacgggtgtgtgaacgtcagctgtcctccgggcctagagagacgcagctgc gccccctgcccggtgtcctgcgcccacgtcagcagcggggccccctgtgacccccccagc tcctgctcctccggttgctggtgtccggacggccaggtgatgagccacgcccagcgatgc gtgtggccgggagagtgtccgtgtgacgtctcaggcgtgcgttactggcccggccagcag gtcaaggtggactgccaggtctgtgtgtgcgagcgagggaagcctcagcggtgtcggccc aatctggactgctcagtgcactgcggctggtcgtcctggtccgggtggggggactgtctg gggccctgcggggtccagagtgtgcagtggtccttccgcagccccaacaaccccagcagg cacggagacgggaggctctgcagagggatctacaggaaggcccgccggtgtcagacggcc ccgtgtgacgagtgtgagtatcagggtcgctcccatgcagtgggagacagatggcggtca gagcgctgccgtttctgccactgcctccccaacctgacggtgcagtgttccctctactgc ccatacgctgtcagcgggtgcccggagggcctgaagttggttcccggcgaggcagacagg tgttgttactgccaaggtgaaaatgccaccgagtctgtcaccaccagccccgacagggtc acctccaaaccagcagggggcagcacacccctggtccccacatatccacttcctcctgaa gacgagtgttgggctcccctgggagtccagactctaccagcgtccagcttcacagcctcg tcccagcaggcgggtcacccccctgaggccgctcgtctgcacgggtgggacatgcacagg gacctccagggctggagtccagagccagaggagtataaggatttaccccagcggagaccg gagggccacgctggtgacacacggagtccctacatacaagtagacctgctgaaaccatac aacatcacgggcgtgctgactcagggcggtggtgcgttcagcaccttcgtgtccagcttc tccctccagttcagcccggatggacaccggtggcacacgtacaaggagctggtgtctgac gcccggccccgagccaaggtttttctggccaactctgatgacggaggtgtggcggagaac agactggacaggatggtgtcggcccggttcgtccgcctgctgccccatgacttcaaaaac ggcatctacctccggcttgaggtcatgggctgcggggatggttcccgttggtcgaccccg actccaccttctccggtctctccggtctctccaggggggtgcagagagaaggagttcagc tgtgggaacggtcgctgtgtgccggcaggccccctgggagtcgtctgtgacggggtgaac gactgcggggacggatcagacgagatgcactgcggcacccagccctcctccacagccccc agcccccgctgcccccccgggcagttctcctgcccccctccagggggctgcatcgacgcg gggctgcgctgtgacggcattcctcactgcccgagaggagaggatgaaagtggatgtcac ccccacgatgccaccactccgtcagtgaggccacacacacccactccttcccctctgaaa actccctccacggctgccgtcaccagccctgctgaggcaccgacagatggcagccctgga tatcatggtgtgtgcgcctctcccctgggactggaggacggcagaattcgctacggtcag ctgacatcgtcctcacatcgggagaacagccctgccgatgctggaaggctgaacatcgtc ccaaacattcaggtgatggaacccggctggagcccgaagcctacagatccgcagccatat ttccaggtggatttcctggaacctgcgtggatctcggggctggtgacgcagggcagtgaa cgcatgtggggttacctcaccaaataccgcctgtcgttcgccctgcacagcagcctgttc acaaactacacagagaacaggaagcctggtggccccaataaggtgtttgaggtgcggatg gtgggcaggaagcccgtgacccgctggctcgggcggctggtccgagctcgctacatgcgc atcatcccggtggagttcaggcaccccttccacctgcgggtggaggtcctgggctgcaga ggagacgagctggtgacccccagcagtgagaccacggccgcgcaccgctgtccaactggc caggtcccgtgccagcacagtgaggagtgtgtcctggtgtcggtgctgtgtgacggccga ccggactgcacggaccactctgacgagaccggctgtggaactacaggttccccaggtctg cttactaccaggtctcaaggtggttttcctggtgtggcaacgcctggagttacaggacca actactccgtctgtctatcctggggtcaccacaggtcaccctggactgcacctcaggaca tcggtccggccgggaaaacctggtcttcaaaccaccgaggccccctcggtcactgcaacc tcccctgatggtggcctacccagggtgctttgcgttcagggacagtttgcatgccggtca tttggctgtgtggactctgcacaagtctgtgatggaggaagggactgcttggatgggtca gatgaagagcgatgcggcaccacggccgggcccccggcgacctcccggctgcccccggtc cccccggtccccagtccctgctcctccaagcagttctcctgtgagagcggggagtgcatc cagatgagccgcaggtgcaacctgcacagggactgtgccgatggctcagatgagaagcac tgtgtggactgcatcatgtctccatggacggcgtggagcagctgcagcgtgacgtgtggc ctgggctccttgttccggcagagggacatcctgagggacgctctgcccgggggctcctgc ggtggagctcagtttgacagcagagcctgcttcctgaaagcctgtccagtgaacggtcat tggtccgagtggacagagtggtctcagtgtgacgccccctgtggaggaggagtccggcag aggatccggacctgctccgcccccccccctaagaacggtggacgagactgtgagggcatg actcagcagagtcacagctgcaacatgcagtcatgcaccaatgagactgggacccagaca ggctgcgtccacggcatggtgctggtgacgagggacgactgccaggctggacgagtcgaa ccctgtcctcctatgtgttcagatgtcagcatgaccagcaactgcactgcagcatgtata gtggggtgccgctgtccccccgggctgttcctgcaggagggccggtgtgtgaacgccagc cggtgtctctgccagtgggagggagaaccactgcagccaggacaggtgatcaggaggaac ccgtgcagcacatgtgtgtgcaaagaggggaacgtgacctgcgacacatccaaatgccgg gccgcctgtcactggtcagcctggtcttcgtggtccccctgtgatgtcacctgcggcgtg gggctgcagcaacgatacaggtctgcggtgaatccagcaggagccgtccagccctgtcca ggagactcctccgaggcccggcgctgtttccaccagtgtctccccggacttccagatgga gcgtggagtaaatggaccgtctggtctgagtgcagtaagacatgtttcagccatgtaaat gatgtcgggattaggcgacgatttcgcggctgcgatcacacacacaatcagtctctctgc cacggggacagtgaggagcaggagccctgcaacactgtacactgtccagttcatggtggt tggtcggcctggtcggcgtggtctgagtgctccactgactgtgactctggtgttcagaca agagagagattctgcagtttaccggcaccgcagcacggtggccatagctgcaccgggcct cacattcagacaagagactgcaactcccacccctgttcaggtgtgtgtccagagggcatg acgtacatgacggtggctgagtgcagggctcagggcggtgcgtgtccgcgggtgtgcctg gacatgacccccgccgaggtgcagtgtgccaccacctgctacgatggctgctactgcggc ccgggtttctacctgttcaacagcagctgcgtgcctttggcccggtgtccctgttaccac cggggggagatgtacccagccagtactcgcctgcctgtcgacgcttgtaataactgtact tgcactaacggagaaatggagtgtggtgctgctccttgcccagtggactgtgggtggagc acttggacagggtggagcgactgcagcagaacgtgtgatgtcggagtgcgaaggcgctac cgttcgggcaccaatcctctcccggcgtacggcggccagccctgcgaagggcagcgagtc ggcatcgatacctgcagcatcgagccctgccttggaaccaaggagccgtggagcgggtgg tccgagtgctcggtgacgtgcggcggaggttacaggacccggacccgcgggcctatcaga atccacggcactgctcagcagttcagtgcctgcaacctgcagccttgtggcggcagcagg gcctgtcctccgggcctggagtggaaacagtgtgtggcgggggccgtgtcctgtctggac atcaccatggagctgagcaggaactgcaccgccggctgccagtgtcctccggggaccgtt cttcaggacggagtctgtgtgccggagtctaactgccgctgtgacgtcgacggagtgcag tacaaccctggagacaccgtcagcagaaagtgcagtaactgcacatgtgaaggaggacgg ctggtcaactgctctcaattcagctgcaactctgatggccagtggtcggggtggaccccc tggggccagtgctcggtgtcgtgcggggccggtctccagtcccgataccggttctgttca actcgccagcagcagtccagcagtgctccgtcatgtgtcggccctcaccgggaagatcaa gtctgtgtcggcggcccatgcgaccgagatggaggctggagtcagtggagtaattggacc gattgcaccaagtcctgtggtggagggatgcggagccggaggagaagttgtgacagcccg gcgccggagggggaggggaactactgcgagggcttgggaaccaaagtcctatcgtgtaac actgaccactgccccgtggctccgtgttcccaggttccaggcacggcgttcagcagctgt gggccgtcctgcccgcggtcgtgtgacgacctggcgcactgtgagtggctctgtgagccc ggctgctactgcaccgaggggaaggtgctgtcggccaacggcacggcgtgtgtccagagg gaggactgcccctgcctggacctgaacactggacgcaggctggaacctgcagagatcacc caggcccctgatggatgcaataactgcacctgccacagtgggaggttcaactgcaccagg aagctctgcccagtttcaggcggctggtgccggtggtccgactggactccctgctccagg acctgcggggctgagtccgtgtcccgctacaggagctgcagctgtcctgaacccaaggct ggaggggagacttgtcccggagaacaggagctccacagcgggactggggttcagatccag agacagccctgccccgtcaccactttctgcccagttcacggttcatggagttcctggtcg gcgtggtcggagtgtgacggctgcaccggttcatccacccgcaccagggagtgcaacagc ccgcccgccagattcggtggcctgccctgtctaggggagggcaggcaaagccgcggttgc catgacaacatcaccgtctgctcagactgcggtgccagccagcaggaatggccctgtggg aagccttgtccccgcgactgctcagatctccatggtgatgccgagtgcctggactccctg gagtgcagccagacctgcggttgtcagggcgacatggtcctgcaggatggagtgtgtgtg ggccaggacgagtgtcgctgcaaatactacaacggctccactgccggtggactggaccct agtaactcatcctgggtgtggcccggtcgatctgattggcagtttgcaaatccaggagac aacatcattagtgactgcagaaactgctcatgtgaggctggggtgatgcattgtcaatcc gtgcccggttgccatgtcgacggggcctggggccaatggggaagctggaccaagtgctcg ctttcctgcggtggaggaatgaaattcaggaaacggctgtgcaacaacccgactcctcag agcggcgggagaggctgcctgggcgactccgaccagcagaggggctgcaacacgcagcag tgcgcagaccctgggggcccgtggctgccctggtctccgtggtcccagtgctcggtcagc tgtgggggggggcagcagtcccgctcccggctctgcagctccccctgccacggcctcagt cgccagagcaaaacctgcaacacacaagtctgcttcgatgtgggctgccctcctggccgc ctgtacagggagtgtgagcgcggagaagactgtcccttcaactgcgcccaggtcagcggc agggagggctgctactccgacggctgtgaggaaggctgtcactgtcccccgcacacctac cagcaccgcggagtctgcctgccggagtgcccgtgtctggtggatgaagagttcctggcc tccctgcagagtgtgtccgtcacccccgtctcctcgctgctgctccataacgtgtcggag ggagctgaactgcagtctggagacacagtggtgcatgaatgcagctcctgttcctgcgag cacggcaggtggaactgctccctggagcactgccccgtggacgggggcctgtccccgtgg ggcccctggagcccctgctcgctctcctgcggaggtctcggggtcaggtcccggttcagg ggctgcacaaagcctgctccggcccacggagggagagactgtcaggggccccgccaggaa acaaccttctgccaggctcccgactgtccagctgttgtcccgacagaggaaccacccact ccagaagaggattctggcttctctccttggtcagtgtggagtccttgcacaaaaacgtgc actgacgttcagaacccggccaggaagtctcggcgtcggcactgcatcaaacctccgtgc tctggaagccctcgggaggagaaggcctgcaacctgccccagtgtccaggtgacatatgt gtgagcaccgactgtgcacgtagaaactgttcgtggacagagtggggggagtggagcccc tgttcacggtcctgtggagtgggacagcagcagaggatcagaactttcctccggcccggc tccaacggctcgtggtgcgaggacatcatcggagggaacctggagcatcagttctgcaac atcgccccctgcaaagttgacggaggctggtcccgctggagtccctggtcccactgtgac aaacgctgcggtggcggacgctccatacgaacgcgctcctgctccagccctccgcccaag aacggtggcaggaggtgtgagggagagaagaaccaggtcaagccctgcaacactaaagca tgtggtgagaagggctgccccccaggccaagagtttgtgcagtgtgcaaaccagtgtccg cagcgctgctccgacctccagcagggcatcgagtgccagggacacgcagaatgtcagcct ggttgtcgctgtcctacaggtcagctgcagcaggacggagcgtgtgtgcagctgtggcag tgcgactgcgtggacgcgctgggacacacttgggcggccggcagccggcaccaggtggac tgtaacaactgcagctgcgcagacggacagctcgtctgcaccaatcacagctgtcagatg agctgcacttggagctcctggtccagttgggcgccatgcagtgtatcctgcggacagggt caaagaagcagatacaggtccctgatcccggagactgaagaaaccatttgccactttgag gaagttcagcagaagtcgtgcgagccgggagcgtgccccccgctctgcctgctggacgag cgggagctcggcgtgggagacacctggctgcagggggagtgcaagcaatgcacatgtacc ccggagggagtttactgtcaggacgtcgactgcagggtggacggaggttggaccccctgg tccgtgtggtccgactgctccgtgacgtgtggtcagggtgcacatgttcgaacccgggcc tgtatcaaccccccgccgcgcaacaacggctcgtcctgcagcggtccggagagggagacc caacactgccagacgcctctctgtctggacgacctgtgtccgtggttgccatggtcaccg tgctcccagagctgcggggcggggactctgtcccgacgcaggaagtgcatgtgtgaggag ggaggagatgtggcgtgtcctcctgaggtggaggcggaaagaaacagggaggagacccag ctgtgctacaagcggccctgtccagcctgtcctatgtcagcgtggagcgtttggtcgcgc tgctcctgccagtctcagaggcagcagcgctaccgtgtcgctctggtcccggccaccagg ggccaacagtgctctcccgtagaaacccagagccggacctgcaccctcagcccctgtgac gcctgcgacgccccgtttgtgtactctgcatgcggcgctccctgtgagaagcagtgtgct ctgctggcaggtggagatctgtgctcggacaccagggagtgctcacctggctgttactgc ccagagggtctgctgcagctgaacggcagctgtgttcctccagacgaatgcggctgcacc ttcgtgcagcacggagctccaggacaaccgcccaaacccgtcgtcgtggcccagggggcc accgtcaccatcggctgcagtagctgcctttgccacaatgggagtttgcattgtgactcc agagagtgtgaggttgtcctgagcgagtggtcggagtggaccccctgctccccctgcgtc ccggcctcctccgagccgctggctgctctcctggaaacggctggtggctcccgcatggtc tccatccagaagcgcttccgtgcgtgtctggacatagattcaggtcttcccacggccaga gaggaggagagccggtgtccggggctgctggtggagcagcggctctgtccagatgtgaac atctgcagagatctgtgtgactggagtgtgtggagcagctggacggcgtgtgcagaccca tgcagcggtggggtcaggcagcgcttcaggcagccccgggcatcaccaccaggaccccgc tgcaagagccagcagacgcagagccagagctgcaacacgggactctgcccaggcgagcgc tgtgaggacagggagcggacctaccaggagacctgcgctaatcgctgtcctcgcagttgt gctgacttatgggagcatgtgcagtgtctccaaggagcctgccactcaggatgtcggtgt ccagaaggccagctgttgcaggacagccgctgtgtgccggtggcagagtgccgttgtggt ctcccatccggcaacgggacgctgcagttccagcccaaagaggaggtgaccgtagactgc aacacctgtgtgtgtgagggtggagttctggtgtgcaccagacggccctgcccggtgtac gaggcctggagctcgtggagcccctgctccgtgtcctgtgggcgaggccagacgacgagg actcggagctgccgtgacgctgtgggcggccccccctgtgctgaaaccacgcagacacaa ggctgtgatctgccctcctgtccagcgggctgtttgctgggccagtggtcggcctggagc gagtgcagcgccacctgtggcggcggcgtgtcactacggaacaagaccgtcctccgagag ccggagccgggcggggccgcctgccccggcccactggagcagcacactatctgcagcacc cagagctgcctgcccgagtgtcccagcgggcaggtctacactaactgttcaggttcttgt ccgtattcctgtgaggacttgtggccacacactcagtgtttgctgggaccctgcacaccc gggtgcaaatgccctccaggacaggtgtggtataagggcgcctgtgtagatcctgctgac tgtccctgttcatcactgtcgctgccagctgaataccagcgttggaacgccaccactgga ggtctcacagacgtgctgctgcagcctggaaccaccgttcagcacctctgcaacacatgt gtgtgccgcgctggggcgttccgctgctccgcagagccctgccatgtggactgccagtgg tccggctggtcgccgtggcgaccctgctcagccagctgcggtagcggtcagcagagctcg gcccgctctgtgctgcagcccagccggtacggaggagccccgtgtgacggcccggccctc cgcacgaccggctgcaccgctccagactgtgcgtgtcctgctggggagcggtggcggagg agcgtgtcggaggagacccccctgtgtgagaggagctgccaggacatctactcttctcct cccgtcaactgcagccgtgcggcggagggctgcgtgtgtcaggaaggcctttaccggaac ccggcggggggctgtgtcatcccggccctctgcccctgcctggaccagggcgtgctgcgg gaggcagcatcagagtgggatgagggctgtctgtcctgcagctgtgtgaacgggaggaag cgttgccagacgaggtgtccccccctctactgtgacgagggagaagtcaaagtggaggaa ccaggcagttgctgtccagtctgcagaaaacagtttccagacgagcccgtgccggagtgt cggcgctacgttcgagcccagaacatcaccaagggagactgcaggctggacaacgtggag gtcagcttctgcaggggacgctgcctgtccaggaccgacgtcatcttggaggagccgtac ctgcgctcagagtgtgagtgctgcagctaccggctggaccaggacaacccggtgcgcttc ctcagcctgcagtgtgagagcggggagagcgagcccgtggtgctccccgtcatacacagc tgcgagtgcactagttgccaagggggggacctgtcccggcgctga

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