Cololabis saira (Pacific saury): 133443208 Help Entry 133443208         CDS       T09849                                  Symbol pkd1a Name (RefSeq) polycystin-1   KO K04985   polycystin 1 Organism csai  Cololabis saira (Pacific saury) Brite KEGG Orthology (KO) [BR:csai00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:csai03037]     133443208 (pkd1a)    04812 Cytoskeleton proteins [BR:csai04812]     133443208 (pkd1a)    04040 Ion channels [BR:csai04040]     133443208 (pkd1a)    04091 Lectins [BR:csai04091]     133443208 (pkd1a) Cilium and associated proteins [BR:csai03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    133443208 (pkd1a) Cytoskeleton proteins [BR:csai04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     133443208 (pkd1a) Ion channels [BR:csai04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    133443208 (pkd1a) Lectins [BR:csai04091]  C-Type lectins   Others    133443208 (pkd1a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PLAT PKD_channel Polycystin_dom LRR_8 Lectin_C LRR_4 PKD_3 WSC GPS LRR_LRWD1 Motif Other DBs NCBI-GeneID:  133443208 NCBI-ProteinID:  XP_061576649 LinkDB All DBs Position 1:complement(33068989..33168677) Genome browser AA seq 4652 aa AA seqDB search MPCGNGQTLTKRKHGVCFPRLSFLPGVLVALCWLQACGSGPAGAGGGSCGPCPVNCSCAP AGPQQLCAVNCSSMGLERAPAAADFPLATAVLDLSKNHISSLDTSLLERLTGLQELYLQG NRINVLPRGVFCCGPLSVLDLSNNQITTIEERICDNLCNLTQIDLSGNPFVCDCKLFRLV RWLQEKGVQVRRPYAMLCNHPSDLRDQPLLNVSLLCGPSYAACLEDSGSGGGPSELVIFT SSNPGNFTREQCNSVCFGLSHLYGGLGDRHECLCSTNNEPNFISESQCSAACTNRHVMTE CGWTLARDVFAVEFSVSLRSLPLQSVHDHILFTAASSVMPVTLSWDFGDLSTRVNTTGTE VTTATHKYGLPGRYTVSLKAWAGHKEFLARTEVTVTLPPMLELHCPPIAVANKSIEVSLV SWGGVGLDVDWTITKNDVQVAKAFPHCTGDRVWHAESSSCFQILPEELSWTDARQQCVNR SGDLAVVRSDALRNLLAPKVTKERGAWLGLSDVDSPGKLRWVNGSEAQEGEEGLPPRSAI SRGNLCVSFDQRGQTSSHLCDAKRAFVCQYTPQVRVPDAGVFMVGMAVFPSHNPRHQASS TSLSAPQQRTISGVELLLFPALSFIQAGRLSSLEFVTGELSSQVHIRFQTYRPHCHYPSQ HLLLPSCGGPVCAPFALCVPNATVNGDPPSCPRLEQWCPFQRRCLPLFSPCQPSSCPNCT HVYHLPPGMQRPRYILQKEVVFTLPAGPAAHVLLQDQLEDILVSRGDVIALQHDGGPSSL LQCQSSPQSSWRQPVFALNTSEWLWLNGTRQLADSSDDPAPDPELDMEALEKDGEGGWVG EVVCPIRVLYVGHNGTQLQGAQLSAGLPRPGLYSLLVNSTETSYPASASCPLRVVPPLGL TILHPPPQNGTLYLQPSNTRLLLRVQSRYLTLASQHGSNVSATFRSECPQEFSHSPGLCE PGLSWGSGVEAAEPSLYAALDLNLGAEEHKSPLKVELEAKSNVTEASLVVAVHLEKPLRD LVVQPDPSRRVLKETLVSYTASVLDGSNPSFKWTLDDKPFFTYYNTVLNVIYQHAATYKL TVKGSNHVSTLTQHFNVTVDQLQPIANLTVKGVPDVVPQGSNQTLTTSVLLDMSVAATFR WSFGDGGYEEFEFKPPYSPSLLCPDSPNQVLLSKNITYIYSQPGIYAALVSVSNRYENIS QSINMSVYSILTRVDLQTEPQLLLVGKSADFEAHPLPSPYGIHYDWDFGDGSARQQGRRV AHTYMEKGVFNVCVSVNNTISSTKACAQMFVYEEIEDLTANSSTPSELNSLTTVWAHLGS GNKISWTFSMGDGKIYTTPEPYVSHRYTKEGNYTVNVTAMNAVSSGWTILPVHVFVFQVI KMEPSGCVQERTNVSFQAWVSGNASIHLYKWSFGDGSPNETLYGNPRVSHTYETSGKYHL SLLLSSGVNKATKANFFNWVCVQPALTSISFIPEKSRYAVGEDVKFHVTAIPDFNYSYHW DFGTEGDLVLKHGSGIIATTYKKPGRYLVTVHVFNNISTGNSSAVIEVLMPIGAVFIQHN GTKSNNLTLGAPYAFMTSSLASNVTYTWNFGNGNILTGQNILYTYNISGTYNITLRAINI ISQNDTVLPVTVLAPIRGLTVNASLINVPLNVSVYFEAHKEEGDGVRYSWIVCDHCTSIS GNNNMFYTFRSVGTFNIIVTAENDVGAAQASIFLFVQRELEGLQILAEEMVVGELDGCCY ATNRVLHLQAGLKEGTNMSFTWNIIRELDPSLFNISGKTVELNFSKPGPCDIFLRAANLL GQLSVNRTIYFIEPVGGVYLQISNNPVAVSASTNLTLLVREGSHLYYQWSVDGNKLQWNK PWLTHNFSNPGQKLITVGVSNEVSSEVVSENVYVQEVISGLSFSAANVAEQSFVATGVNI SLQGEVLTGTNVTWTWLLEGRTQTGRESSVIFREPKTAIVTLNATNDVSGQVVSKEFFVE EKIQWLELRSSTKLAAVNEKVEFTISMAGGSNVQLILSINGDPTTDLKPNQTYTHVFTRV DTYMVNLTAHNQVSFLWHHVHVVVLEPVRGLAIEKIPKAIPVGENQVFKASINTGNPVSF LWTFDLHMHQASRVGKQVHYTPADQGSLTIYLKAFNNLHGQNITEHILVQHKLQSASLHA VPQDTFINKTVRLEASVMPRSNPLECMWHFGDGSKPVQTKGTIVDYKYRIPGPYLVQVNC SNRVSWVLAQVVVSIGVLECEEPEVQVAQTRLVIWRSQPTFVEASVDLKGCTRYGAQYLW RIFSASCGDDEIMKDGLETRFSPSQAVRLPVEVDVRRLQLSLPKMSLAAGNYSLVFSLSY KSVPLRKAACLHLSVMAAKLKPIIEGGTYRVWSKTQDLQLSAEQSYDPNMDPDSQSLLHY HWECHGTSEGPEYCSNLNFGLGSSGPVLGISGDELEAGIEYTFKLTISKDGMDPESTTQT VLVQSGDIPMVYLECVSCKAQSIYEVSHNSYVYLKGRCSNCHGFHRGRWSAMNLRNKTLV LDYSSTTTGSDGMNLVLRKGILKDGDSYIFTLHVIDSDLDGEGAASITLHHNNPPEGGEC HLRGEGEAGTVYGDGSIEGWRIRSLLDHVHFNCSGYSDLGVSETPFVYSLLVTRCREDYC EDLCIYKGSSQEYSAFLPPGFRSARHRVSVYITVEDHQGAASLALNKTIEVVLPDPPPEY SSLPHWLSELIDTKLKKLLEQGDSQKVRELSLALITVLNEYERTRKSSRVSRDERNYRVR VRSNITRALTALDLTTVSDIQQTSAALAQCTAVSREFICEECQNSTLNKLESMLEILQTD TKQGTVTPTEIADNILNIMGDLIHQVSQSASNSNFQPAYVDSPSPSSSFSISPGEEHGNA LLDASPASLEPHPLRVAAKAYSLSSVLMLILMHARVLNEEPLILGGAEIAATGKLADPQS LLCYHGNNSPECQRFSIPRAFDKSLGKVASGNSIMQLLFQVDSNPFPFNYVSNYAVSTEV ASMEFRTENGTHIPISGLDDSLAITVAVNNASSGDAGAEDSGARGVPTAGAVNISHCDSV VVRVSTGNDNRQAGLFVQLNFTTLEVVREKDERENVEEEPFVTAFLHSHEHPNEFNCTER KRITLSMTKGEDHKKYTFFLSPEIYDTTLDYFINVSTPCSPGARPVGVHLEVGVFASLCQ YFSESEKQWRTDGMVPLAETNSSRAVCRTRHLTAFAAGLFVPTNAVSFKMPERLSAPSLV VLLVCILGLLSYVVAAAILHKLDQLDLRRAGVVPLCGRDGLFKYEVQVKTGWSRSAGTTA HVGISLYGRESRSGHRHLDSRGAFTRNALDIFHIATDTSLGSVWKIRVWHDNKGLSPAWM LQYVLVKDLQTGSSYFFLVDEWLSVDSEKTDGRVEIEVEASEEAVLRRLPRLLRCELQRA LCESHLWLSLWERPPRSPFTRLQRATCCAVLLQLFLLANTLWYGTVVDNRYSPRAVSRLS SLDGETVAAGLVTCLVVYPLYLLVFTLFRMSRSKCVTVEQVPPQTDQESVEIDDFLDNSM AGSSFLFFNGETNSEETNVDFPTPSINSEDSWDMADGDTEDRDWPELLSDVSVVGGAGHG AGMPRLKRGQGSRHLGVDMTFGPDEEKGADQHNKYFTSSDEDLIKHILADGQNFFPQADE SEMADLSSIFGDKTEVILLQKLSDPLPLESLRRDPPKTAFISNTVVTDVCRPRRFPPWCG RAAMWGSWAGIALASAVSIWAGYGFSGSMAMRWLISCFASLSCSCLLLEPIKVFCEAVYY ALCVRRLRPEDQDVLVEFPRVERVVQRVTRVRPPQGFALSQARNQARKVHMLHTMLKNFL LYMFFLLVALLLNYSDSAKDAHSLRLRTQLQQALPTPEYHTISSRDDVLKWLNGSLLPRL LNEPLLMRDTGSILLGTVRLRQVRDAQGGFRAISPRGKSWVTTPTAGNGNVSVSGAIDAD RVWHRGEMGTYNSRDVVHQLNRSLDEASSSLQQLQQLHWLSHRTRGVSVEFSLYNINTNL LAVFSFLFEFPVSERAQSSLDLVVFTLWPVTGLDLQLLLSMVLLALVLYFLVRGVLGFLS EGYGYLLSVWRFLGICKLCLAASVCGLHLSRSVMAAQLWASFLKHPRDVFTDFSPLARQS QLYTIVSATLLFILVLKASHQLRFLREWAVFGRALRRSVWELLGVSLVLLLLLLAYSHTG HLLFHSVLDGYGSVMSACLSLLGVGRRGLLAWRPAVTMTGPSSTISSLVFHVSFAILRLV FLWLVISVILRNYRRARAELYRPAVDLQDHEMVELFLRRLKMWMGLSRAKEFRHKVRFEG MELPPSRSSSTSDCKSLCLPPLDSPDSPPSPDSVDAGSEASWRPASSSPCSLTEAPGISL GLGLGLGLGVGLGSGTGVGGTSWRERAETEASLRRLLPTLDALLQQLDRVTVATEDVYHV ECKLERTQRKRKRKERKREKGDYGQGGRSEAKQRGKGEDKDQREQKTGKDKHKGSRKGKK TEKSELSKESWSSPGNTRKTPAATPVPFLKPKPATASVHPPTPQSSLKCSVSAAPPSPLT GKCATDLHPLPVSSSSTLPPRTPTAPSSVRAPVTSMPPTPGSTPISRDWDPLSDRDALPY SSPFNHPAHTATIPKRKRKRKPPPLKNKVHPT NT seq 13959 nt NT seq  +upstreamnt  +downstreamnt atgccttgtggaaatggacagactttaaccaagcgaaaacatggcgtctgcttcccgagg cttagctttctccccggcgtgcttgtggcgctgtgctggctgcaggcgtgcggctccggg ccggcgggggccggcggcggcagctgcggcccctgccccgttaactgcagctgcgcgccg gcggggccgcagcagctctgcgccgtcaactgctccagcatgggactggagagggcccca gcggcggcagacttcccgctggccaccgctgtgctagatctgtccaagaaccacatctcc tccctggataccagcctgctagaacgcctcaccggcctccaggagctataccttcaaggg aaccggatcaatgttctccccagaggagttttctgctgtggaccgctgtcagtcctggat ttgagcaacaaccaaatcaccaccatcgaagaaaggatatgtgacaacttgtgcaattta actcaaatcgatctgagcggcaacccgtttgtgtgtgattgtaagctgttccggttggtg aggtggctccaggagaaaggggtgcaagttcgacgcccgtatgccatgctctgcaaccat ccctctgaccttcgcgaccaacctttgctcaatgtcagcctgctctgcggtccgagttat gcggcttgtctcgaggacagcggcagtggaggaggaccaagtgagctcgttatcttcact tcttccaacccgggaaacttcacccgtgaacagtgcaacagtgtgtgctttggtttgtcg cacctctacgggggcctgggggacaggcacgagtgtctctgcagcaccaacaacgagccc aacttcatcagcgaatcccagtgctcggccgcctgcaccaaccgccacgtaatgacggaa tgtgggtggactctggctcgcgatgtgtttgcggtggagttctcggtttcactgagaagt ctcccactgcaaagcgttcatgaccacatccttttcaccgccgcctcctctgtcatgcct gtgacactctcctgggacttcggcgacctttcaacgcgggtcaacactacaggaacagag gtcaccacagcgactcacaaatatggacttccaggtcgctatacagtcagtttgaaggcc tgggctggacacaaggagttcctggcacgcacagaggtgactgtgactcttcctcccatg ctggagttgcactgtcctcccatcgctgtggccaataagagcatcgaagtctctcttgtc agctggggcggcgtcggcttggatgtagactggacgataacaaagaacgatgtccaagtt gccaaagccttccctcactgcacgggagatagagtgtggcacgccgagtcctcgagctgt ttccagatccttccagaggagctgagctggacggatgcacggcagcagtgtgtgaatcgc agcggggacctggcagtagtcaggagtgacgcgttgcgtaacctgctggcaccaaaagtc acaaaggagcggggtgcgtggctggggttgagtgacgtcgactctccgggcaagctgcgc tgggtgaacggatcagaggcccaggagggagaagagggcctgccacctcggtcggcaatc tcccgcggaaacttgtgcgtgtccttcgatcagcgcggccagacgagttcacacctgtgt gatgctaagcgtgccttcgtctgccagtataccccccaagtgcgtgttccagatgccggg gttttcatggtcggcatggctgtgtttccctcccataatcccagacaccaagcttcatcc acttcactctctgctccacagcagcgcaccatcagcggcgtagagctgctgttgttccct gcacttagcttcattcaggcaggccgtctgtcctccctggagtttgtcactggagagctg agttcacaagtccatataagattccagacctacagaccccactgccattatcccagccag cacctgctgctgcccagttgtggaggtccggtgtgtgctccgtttgcactttgtgtcccg aacgccacagtgaacggcgacccaccttcttgcccccggctggagcagtggtgtcccttt cagcgccggtgtctgcccctctttagtccatgccagccatcctcctgtcccaactgcacc catgtgtaccacctgccacccgggatgcagaggcctcgttacatattgcagaaagaggtg gtatttactctaccagcaggaccagcagctcacgtgctgttacaagaccagctggaggac attctggtttcacgtggcgatgtcatcgccctgcagcacgacggcggcccatcctctctt cttcagtgccaatcttctccacagtcgtcgtggcgacagcctgtttttgcccttaacaca tcagaatggctgtggctgaacggtaccagacagttggcagattcttcggatgaccccgcg cctgacccggagcttgacatggaggctttggagaaggatggcgagggaggctgggtgggg gaagtggtctgcccaatcagagtgctctatgtgggacacaacgggacccagctgcaggga gcgcagctgtctgcaggtctgcccaggccgggactgtacagcctgctggtgaattcaaca gagacgtcatacccagcctcagcgtcgtgcccgctgcgggtggtgcctcctctgggtttg acaattctccaccctcctccgcaaaatggtacactgtatttgcagcccagcaacacccgg cttctactccgggtgcagtctcgctacctgacactggcatctcagcatggcagcaatgtc agcgctactttccgctccgaatgcccccaagagttttcgcacagtccgggactctgtgag cccgggttgagctggggttcaggcgtggaggcggccgagcccagcctgtacgcggccctg gatctgaacctgggagcagaggaacacaagagtccgctgaaggtggagctggaagccaaa agtaatgtgacagaggccagtctggtggtggctgttcacctggaaaagccactgagagac ctggtggtgcagccggacccgtcacgcagggtactgaaggagacgctcgtgagctacacc gcttcggtcctggacggttccaatccctcgttcaaatggacactggatgacaagcccttc ttcacctattacaacactgtcctcaacgtcatctaccaacacgccgccacctacaagctc acggtgaagggctcaaaccacgtcagcacgctcacacagcatttcaacgtcacggtggat cagctgcagcccattgccaacctcacagtcaagggtgtgccagatgtcgtccctcagggc tccaatcagactctcaccacctccgtgctcttggacatgtcggtggcagccaccttccga tggtctttcggtgacggaggatatgaggagtttgagttcaagcctccctattctccatcc ctcctctgtccagactctcctaatcaagtccttctcagcaaaaacatcacctatatttat tctcagccaggaatatatgcagcgctggtgtcggtgtccaatcgttacgagaacatcagt cagagcattaacatgagtgtttacagcatcctgacccgtgttgatctacaaacggagcct caactcctcctggtggggaagtcggctgatttcgaggctcaccctctgccttccccgtat ggaattcactatgactgggactttggagacggttctgcccggcagcaaggtcgccgcgtg gcgcacacctacatggaaaaaggcgtgttcaatgtctgtgtgtcggtaaacaacaccatc agctccactaaggcttgcgctcagatgtttgtttatgaggagattgaagatctgacggct aacagctccacgccctcggagctcaacagtctcaccacggtgtgggcacatcttggctct ggtaataaaatctcatggaccttttcaatgggtgatggcaagatctacactactcctgag ccctatgtgtcacacagatacacaaaagaaggcaactacaccgtaaacgtaactgccatg aatgcagtgagctctggttggaccatacttccagttcatgtctttgtcttccaagttata aaaatggaaccatccggatgtgtccaggagcgaaccaatgttagttttcaagcctgggtt tctggtaatgcatcaattcatctttataaatggagctttggggacgggagccccaacgag acactctacggaaaccccagagtctcacacacctatgagacgagcgggaagtaccacctc tccctgctcctgtccagcggagtcaacaaggccaccaaggccaatttcttcaactgggtg tgtgtgcaaccggcactgaccagcataagcttcatcccagagaaatcccgctacgccgtc ggcgaggatgtaaagttccacgtcacagccattcctgattttaactacagctatcactgg gacttcggcacagagggggaccttgtgctcaaacatggttctgggattattgcgacaacc tataaaaaaccaggccgctacttagtgacagtacatgtcttcaataacatctctacaggt aacagcagtgctgtgattgaagttctgatgcctattggagcagtttttattcaacataac ggcacaaaatccaacaacctgacacttggggctccatacgctttcatgacttcttcctta gcctccaatgtcacttacacttggaattttggaaatggaaatatccttactggccagaat atcctctatacgtacaacatctccgggacctacaacatcacattgagagcgatcaacatt atcagccagaatgacactgttctccccgtcacagtgctcgcacctatccgtgggttgacg gtcaatgccagtttaataaatgtccctctgaatgtctcagtctactttgaggcccacaag gaggagggagatggtgtccggtattcttggatagtgtgtgatcactgcacctccatatca ggaaataacaacatgttctacaccttccgctctgttggcacattcaacatcatcgtgaca gcggagaacgacgttggagcagcacaagcgagcatcttcctgtttgtccagcgtgagttg gagggtctgcagattttagcagaggaaatggtcgtaggtgaattggacggctgttgctat gccacaaatcgtgtccttcaccttcaggcaggactgaaggagggcaccaacatgagtttt acgtggaacatcatcagagagttggatccttccttgttcaacataagtggtaaaaccgtg gagctgaatttctcaaaaccaggcccgtgtgacatctttctacgggcagccaacctcctc ggccagctgtctgtcaacagaaccatctacttcattgaaccagtcggaggcgtgtacctg cagatcagcaacaacccagttgctgtgagtgcttcaacaaacctgacgttgctggttagg gaaggttcacatctgtactatcagtggtctgtagatgggaacaagctacagtggaacaag ccctggttgacccacaacttcagcaatccaggtcaaaaactaattactgtgggggtctcc aatgaagttagctcagaagtggtgtcggagaatgtttatgtccaggaagtcatttctggg ttgagtttctcagccgccaatgtggctgagcagagtttcgtagcaacaggagtcaacatt tctctgcaaggagaagtgctgacaggaacaaatgttacgtggacatggctactggaagga cggactcaaacaggaagggaatcatcagtgatctttcgggagccaaagacggccatcgtt actttaaatgccaccaatgatgtcagtgggcaagtagtttcaaaggagttctttgttgag gagaagattcagtggttggagctcaggtcgagtacaaagctcgcagcggtcaacgagaaa gtggaattcaccatttccatggcagggggttcgaatgttcagctgatcctcagcatcaac ggcgatcctacgactgaccttaaacctaaccagacctacacccatgtcttcaccagggtg gatacgtacatggtgaatctcaccgctcacaaccaggtgagttttttgtggcaccatgtc catgtggtggtattggagccggtgcgtggacttgccatcgagaaaatccctaaagcgatt cccgttggtgagaatcaagtgtttaaagccagcatcaacacgggcaaccctgttagtttc ctgtggacttttgatctgcacatgcaccaggcgtcgcgagttggcaaacaggtgcactac accccagcagatcaaggttcactgaccatctatctcaaggcctttaacaatctgcatggt cagaacatcaccgagcacatattggtgcagcacaagctgcagtctgctagtctgcatgca gtaccgcaggacactttcatcaacaagacggtgaggctggaggcctccgtcatgcccaga tctaatcctctggaatgcatgtggcactttggtgacggctctaaaccagtgcagaccaaa ggcaccatagtggactacaaatacagaattcctggaccctaccttgtacaagtgaactgc agtaaccgggtgagctgggtgttggcccaggtggtggtgagcataggcgtgttggagtgc gaggagccagaagtgcaggtggctcagacgcgtctggtcatctggcgctcacagcccact tttgtggaggccagtgtggatttgaaaggctgcacacgctacggggcccagtacctctgg aggatattctcagcgtcttgtggcgatgatgaaataatgaaagacggattggagactcgg ttttctcccagccaagcggttcgcctgccagtggaggtggatgtgcgacggctccagctg tcattaccgaagatgtctttggcagctggcaactatagcttagtgttttctctgtcgtac aaaagcgtaccactaaggaaggctgcctgtctgcacctcagtgtcatggctgccaagctg aagcccattatagaaggaggcacctaccgggtgtggtcgaagacgcaggacctgcagctc agtgcagagcagtcctacgaccccaacatggacccagacagccagtctttactgcactac cactgggagtgtcacggtacttctgagggtccagagtactgctccaatctgaacttcggc cttggctccagcggtcctgtgctgggaatctctggcgatgaacttgaagcaggcatcgag tacactttcaaattaaccatcagcaaagacggcatggatccggagtccaccacacagact gtgctcgtgcagagtggcgacattcccatggtgtatctggagtgtgtgtcctgtaaggct cagtccatttatgaggtcagccataactcgtatgtttacctcaaaggaagatgctccaac tgccatggctttcatcgtgggcggtggagtgcaatgaatcttcgcaacaagactctggtc ctggactactcctccaccaccacgggaagtgacggcatgaatctggtgctgcgaaagggc atcctgaaagatggggattcctacattttcactctgcacgtgattgacagcgatctggat ggcgagggcgctgcctcgatcacgttgcaccataacaatcctccagaaggtggagagtgt cacctgagaggggaaggggaggcgggaacggtgtatggggatggcagcattgaaggctgg aggatacgctccctgctggaccacgttcactttaattgctcaggttatagcgatctgggt gtctcagaaactccctttgtgtatagcctgctggtgacgcgctgcagggaagactactgc gaggacctctgcatttacaaaggcagcagtcaggagtactctgccttcttgccaccaggc ttcagatcagctcgacaccgtgtgtccgtgtacatcacagtggaggaccaccagggggct gccagcctcgcactcaataagaccattgaggttgtgttgccagatccacccccagagtac agcagtctacctcactggctgtctgagctgatagacaccaaactcaaaaaactgctggaa cagggagactcccaaaaggtcagagagttatcgctggctctcattacagtcctaaatgag tacgagcggaccagaaagtcatcccgggtgtctcgagatgaacgcaattacagagtcaga gtccgcagcaacatcacaagagctctgactgctcttgacctgactacagttagtgacatc caacaaacctccgctgccctggcacagtgcacggcggtgagtcgagagttcatctgtgag gagtgtcagaacagcactttaaacaagctggagtccatgctggagattctgcagacagac accaagcaaggcaccgtcacgccaactgaaatagccgataacatcctaaacatcatggga gatctgatccatcaggtcagccagtcggcctccaattcaaacttccagcctgcctacgtg gattctccctccccctcttcttccttctccatttctcccggtgaagagcatggaaacgcc ctgttggacgcctcgcccgcctcactggagccacaccctctgcgtgtggcggccaaggcc tacagcctgtcgtcggtcctgatgctgatcctcatgcacgcccgtgtgctcaacgaggag ccgctcattctcgggggggctgagatcgctgccacaggaaaactagcagatcctcagagt ctgctctgctaccatggcaacaacagtccagagtgccagcggttctccatcccccgagct ttcgacaaaagtctcggtaaagttgcttcaggaaatagcatcatgcagctactttttcag gttgattccaatccgttccctttcaactacgtgtccaactacgctgtctccactgaagtg gcatccatggagtttcgcactgaaaatggcacacatatcccaatctctggattagatgat agtctggccatcacagttgccgttaacaacgccagcagtggagatgctggtgctgaggac tctggcgcaaggggggtccccactgccggagccgtaaacataagccactgcgactccgtt gtggtcagggtgagcacaggaaacgacaacaggcaagcagggctgtttgtgcagctcaac ttcaccactttggaagttgtaagagagaaggatgaaagagaaaatgtagaagaggagcca ttcgtaactgcttttctccactcccatgagcatccaaacgagttcaactgcacggaaaga aagcgcatcacactcagcatgaccaagggggaggatcacaagaaatacaccttcttcctg tcaccagaaatctatgacaccactctcgactacttcatcaacgtaagcacgccctgcagc cctggcgctcggcccgtcggtgttcatctggaggtcggggtgtttgcctccctgtgccag tacttcagcgagagtgaaaagcagtggcggacagatggcatggttcccctggcagagacc aactccagcagagcagtgtgccgcaccagacacctcacagccttcgctgcgggtctcttc gtaccgaccaacgctgtcagctttaaaatgccagagcgtttgagtgcgccgagtctggtg gtgctgttggtgtgcatattgggcttgctaagctacgtcgttgctgcggcgatcctgcac aaactggaccagctggatctgcgacgagccggcgtggttccgctctgtggccgagatgga ctgttcaagtacgaggtccaggtcaaaactggctggagccggagtgcaggcacaacggct cacgtgggcatcagtctgtatggaagagagagccgcagcggacaccgccatctcgacagc cgaggggctttcacacgtaatgctcttgacatctttcacatcgccacggacaccagcctg ggtagcgtgtggaaaatacgggtttggcatgacaacaaaggtctgtctccagcgtggatg ctgcagtacgtcctggtcaaagacctgcagacgggaagcagctacttcttcctggttgac gagtggctgtcggttgactctgaaaaaacggatggacgagtggagattgaagtggaggcc tcagaggaggctgtgcttcgtcggctgccgcgcctcctgcgttgtgaattgcagagggcg ctgtgtgagagtcacctgtggctttcgctgtgggagagacccccgcgcagccccttcacc cgcctgcagagagccacatgctgcgccgtgttactgcagctcttcctgttggccaacact ctgtggtacggcaccgtggtggacaacagatacagccccagggctgtgtcgaggttgtcc tcattagatggagagacagtggcagccggcttggtgacctgtctggtcgtctaccctctc tacctgcttgtcttcactctattcagaatgagccgcagcaagtgtgtaacggtggagcag gtaccaccgcaaacggatcaggaatcggtggagatcgatgacttcctggacaactccatg gcgggaagttccttcctcttctttaatggcgagaccaactccgaggaaacaaacgtggat tttcctactccatcaatcaacagtgaagacagctgggacatggcagacggggacacggag gacagagattggccggagctactgagtgacgtgtcggtggtgggaggggcgggacacggc gcagggatgccccggctgaagaggggtcaggggagccgacacctgggggtcgacatgacc ttcggccctgatgaggagaagggtgctgaccagcacaacaaatacttcacctcatctgat gaggatcttatcaagcacatactggcagacgggcagaacttctttccccaggcggatgaa agtgagatggccgacctgtcaagtatttttggagataagactgaagtgattctccttcaa aagctcagcgacccccttcctctcgaatctctccgaagggacccgccgaaaacggctttc atctccaatacagttgttacggacgtgtgccgccccagaaggttccccccctggtgtgga cgcgccgccatgtggggcagctgggctgggatcgctctggccagcgccgtttccatttgg gccggctacggcttcagtgggagcatggccatgaggtggttaatctcctgctttgccagt ttgtcgtgctcctgcctgctcttggagccgattaaggtgttctgtgaagcggtctactac gctctctgtgtgagacggctgcgtccagaagaccaggacgtgctggtggagttccctcgg gtggagagagtagtccagcgggtcaccagggtgagaccgccgcagggctttgctctgtct caagcccgcaaccaggcgcgcaaggtccacatgctgcacaccatgctaaagaatttcctg ctttacatgtttttccttttggtcgccttgctcctgaactactctgactcagccaaagac gctcacagcttgagactgcggactcagctgcagcaagccttacccacaccggagtaccac actatcagcagccgagatgatgttctgaagtggctgaatgggtctttgttgccacggcta cttaatgagccattactcatgagagacacaggaagcatcttgctcggcacagtgagactg cgccaggtccgggacgcacagggcgggttcagggcgatatctcctcggggaaagagctgg gttaccactccgactgcaggcaatgggaatgtctccgtttctggtgctattgatgcagat cgggtgtggcatcggggtgagatggggacgtacaacagcagagatgtggttcaccagctg aacagaagcctggacgaggcctcttcctccctgcagcagctgcagcagctgcactggctc agccacaggactcgtggcgtgtccgtggagttctccctctacaacatcaacacaaacctg ctggccgtcttctccttcttgtttgagtttccggtgtccgagcgtgcccagtccagcctg gatcttgttgtcttcactctgtggccagttacaggcttggatctacaacttcttctctcg atggttctgctggcgttggtgttgtatttcctggtgcggggagtcctgggttttctcagt gaaggttacggctacctcctgtccgtttggaggttcttgggtatctgtaaattatgtctg gcagcgtctgtgtgtgggctacacctgagccgctccgtcatggccgcacagctgtgggcg tcgttcctgaagcacccgcgggacgtcttcacagacttctcccccctggccaggcagagc caactgtacaccatcgtgtctgccacgctattgttcatactggtgctcaaggcgtcccac cagctgcggttcctgcgagagtgggctgtgtttggccgggcactgcgacgctccgtgtgg gagctgctgggagtctccctggtccttctgctgttactgctggcttattcacacacagga cacctgctcttccactcggtgctggacggctacggcagtgtgatgtccgcctgtctgtcc ctgctgggcgttggcagacgaggtttgttggcatggcgccctgcagtgacgatgaccggt ccctccagcaccatctcctcattggtgttccacgtgagcttcgccatacttcggctggta tttctgtggttggtcatttctgtgatactgagaaattaccggcgtgcacgagcggagttg taccgtcctgccgtggatctccaagaccacgagatggttgagctcttcctcagacgactc aaaatgtggatgggactcagccgggccaaggagttccgtcacaaagtgcgcttcgaaggc atggagcttcctccgtcccgctcgtcctccaccagcgactgcaagtccctgtgtttgccc ccactggacagtccagactccccacccagtccagacagcgtcgatgctggatccgaggcg tcgtggcgcccggcgtcgtccagcccctgcagcctgaccgaagccccggggatcagcctg ggtctgggactgggcctggggctgggcgtggggctcggctcaggaaccggagtgggagga accagctggagggagagagcggagacagaagcctctctacggaggctcctccccaccctg gacgccttgctgcagcagcttgaccgtgtcaccgtggcaactgaggacgtgtaccacgtc gagtgtaaactggagcgaacccagaggaagaggaagcgtaaggagagaaaaagagaaaag ggagattatggtcagggagggaggagtgaagctaaacagagagggaagggggaggacaag gaccagagggaacaaaagactggaaaggacaaacacaagggaagcaggaagggtaaaaag acagagaaaagtgaactttcaaaagaatcctggagcagtcccggtaacaccagaaagact cctgcagccacacctgttccttttttaaagccgaagccagcgacggcctctgtgcatcct cccaccccacaatcttcactgaaatgttcagtcagcgctgctccgccctccccactcaca ggtaaatgtgccactgaccttcaccctctgccggtgtcatcatcaagcactctgccaccc agaacacccactgccccgtcaagcgtgcgtgcgcctgtcacttccatgccacctacccct ggatcaacgcccatttccagagactgggatcctctcagtgacagagacgccctcccctac tcgagtccgttcaatcacccagctcacactgccacaatccccaagcgtaagaggaaacgg aaaccgccccctctcaaaaataaggtgcacccaacttag

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