Caldicellulosiruptor saccharolyticus: Csac_1146
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Entry
Csac_1146 CDS
T00506
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
csc
Caldicellulosiruptor saccharolyticus
Pathway
csc00290
Valine, leucine and isoleucine biosynthesis
csc00620
Pyruvate metabolism
csc01100
Metabolic pathways
csc01110
Biosynthesis of secondary metabolites
csc01210
2-Oxocarboxylic acid metabolism
csc01230
Biosynthesis of amino acids
Module
csc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
csc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Csac_1146
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Csac_1146
Enzymes [BR:
csc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Csac_1146
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Ecm33
Motif
Other DBs
NCBI-ProteinID:
ABP66754
UniProt:
A4XIL9
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Position
1301864..1303444
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AA seq
526 aa
AA seq
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MEDNKTIIIYDSTLRDGAQAGGISYTLEDKLKIVERLDKFGVKFIEAGNPGSNIKDQEFF
ARVKKMKLKNAKLIAFGSTRRVGIDVKDDINIQSLIAANTEAVAIFGKSWDFHVKEVLKT
TEDENLQMIYDTIKYLKSLGKYVVFDAEHFFDGYKNNRKYALETLKVAKEAGADSLDLCD
TNGGTFPMDIYNITKEVVEMFPGTLIGIHCHNDTGMAVANSIMAVLAGARQVQGTINGYG
ERCGNADLITLIPNLQLKLGFKCVPDENIKHLTSLSRYVAEIANMIPNERAPYVGAYAFT
HKAGMHIDAVKKNPASFEHVNPEIVGNTRRIVLSEVAGRSTILDKIREIDPTVTKDSPVT
KEIIDELKRLENEGYQFESAEASFEMLIRKKLGLYQPFFTLKEFKVLINEPAVEYSSSAI
VKIAVDGVTAITAAEGDGPVHALDNALRKALEKFYPELKEVHLVDYKVRVLNAETATAAK
VRVLIESTDGKDTWTTVGVSTDIVNASWIALVDSLEYKLCKEKVGK
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
gtggaagataataagaccatcatcatctatgactcaaccttaagagacggtgctcaggct
gggggaatttcatatactttggaagataagctcaagattgtagagaggcttgacaaattt
ggtgtgaaatttatcgaagcaggcaatcccggctctaacatcaaggaccaggagtttttt
gcaagagttaaaaagatgaaattgaaaaatgcaaagcttatagcttttggttcgacaaga
cgagtgggaattgacgtgaaagatgatattaacattcagtcactaattgcagctaatacc
gaagctgttgcaatctttggcaaatcgtgggattttcatgtcaaagaggtcttaaaaaca
acagaggacgaaaatcttcaaatgatttatgacacaataaaatatttaaagtccttgggc
aagtatgttgtatttgacgcagagcacttttttgatgggtataagaataacagaaaatac
gctttggagactttaaaggttgcaaaagaggcaggtgcagactctttagacctgtgcgat
acaaatggtggtacttttccaatggatatttacaacataacaaaagaagttgttgagatg
tttcctgggacattaattggtattcactgtcacaacgatacaggtatggctgttgcaaac
tcaatcatggcagttttggcaggagcacgtcaggtacagggaactataaacggatatggt
gagagatgtggaaatgcagaccttatcacgctcattccaaatcttcagctaaagcttgga
tttaaatgtgtaccagatgagaacataaaacacctgacatctctttcaaggtatgttgca
gaaatagcaaacatgattccaaacgaaagagcaccatatgttggagcgtatgcgtttact
cacaaggctggtatgcatattgatgcagtcaagaaaaatccagcatcttttgagcatgtt
aaccctgaaattgttggaaacacaagaagaatagtactgtctgaggttgcaggaagatct
acaattcttgacaagattcgcgaaattgacccgacagttacaaaagactcacctgtgaca
aaagagattattgatgagctaaaacgtcttgaaaacgaaggatatcagtttgaatctgca
gaggcttcatttgagatgttaattaggaaaaagctggggctttatcagccgttctttact
ctaaaagaatttaaagttctcattaatgaaccggcagtagagtacagctcatctgcaatt
gtcaagattgcagtagatggtgtcacagcaatcacagcagcagaaggtgatggtcctgtt
catgctttagataatgctttgagaaaagctttggaaaagttctatcctgagctcaaagag
gttcatcttgttgactacaaagtaagagtgctcaacgccgagacagcaactgctgcaaag
gtaagggttctgattgagtcaacagacggaaaagacacatggacaactgtaggtgtttca
acagacattgtaaatgcaagctggattgcacttgtggattcgcttgagtataaactctgc
aaagaaaaagtggggaaataa
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