Clostridium scindens: HDCHBGLK_01423
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Entry
HDCHBGLK_01423 CDS
T06591
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
csci
Clostridium scindens
Pathway
csci00300
Lysine biosynthesis
csci00550
Peptidoglycan biosynthesis
csci01100
Metabolic pathways
csci01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
csci00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HDCHBGLK_01423 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HDCHBGLK_01423 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HDCHBGLK_01423 (murF)
Enzymes [BR:
csci01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HDCHBGLK_01423 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QBF74027
UniProt:
B0NI27
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All DBs
Position
complement(1404188..1405561)
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AA seq
457 aa
AA seq
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MKNLTLENITKACKGVYHGDESKLGREVGGVVIDSRKVQKDYLFVAIDGENVNAHQFIPD
TIEKGALCVISHEDLGDTDFSYILVESTGQALLDIAKLYRDSFDVKVVGITGSVGKTSTK
EMIASVVAQKYKVHKTIGNFNNEWGLPLTIFELNEDHQVAILEMGVNHFGEMRRLSSVAS
PDICVITNIGVAHLEFFKTREGILQEKSKMIQDMKDGGTIIFNGDDDLLSQAGPIKGATP
ILFGLGDNCQFYADNIQPMGLRGTSCTIHLPDEYSFECVVPLPGTHMISNALAGAAVGYT
LHLTSEEIKAGIEGLPSIPGRNNIIKTDRLIILDDCYNANPVSMKAAIDVLDMAIGRKVA
VLGNMGELGNNEKVLHREVGEYAAAHGIDLVCGIGHLAKELVDGATNGSSSTRGLWFENK
ADFLDAMKDLIKDGDNVLVKASHGMDLTTIVEALKNI
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaccttaccctagaaaacattaccaaagcctgtaaaggcgtctatcacggagac
gaaagcaagctgggcagggaagtaggaggagtagtgatcgatagtcggaaggtacagaag
gattatctgttcgtcgcaatagacggcgagaatgtcaatgcccatcagttcatccctgat
actatagaaaaaggcgcattatgcgtcatttcccacgaagaccttggagatacggatttc
tcttacatcctggtagaatccaccggacaagcgcttcttgatattgccaaactgtaccgg
gattcctttgacgtcaaggttgtgggaattaccggaagcgtgggaaagacaagcaccaaa
gagatgatcgcttctgtagtcgcccagaaatataaggtacacaagaccattggcaacttc
aataacgagtggggacttcctcttacaatctttgaattgaacgaagatcatcaggtggcc
atactggaaatgggcgtcaaccatttcggcgagatgcgccgcctctcttcggttgccagc
ccggatatctgcgtcattaccaatatcggcgttgcgcacctggaattcttcaagacccgc
gaaggcattctccaggagaagtcgaagatgattcaggatatgaaggatggcggaaccatc
atatttaacggagacgatgaccttctctcgcaggctggcccaatcaaaggcgccactcct
atacttttcggacttggagataactgccagttctatgctgacaatatccagcccatgggg
cttagaggaacctcctgcacgatccatctgccggatgaatactcctttgaatgcgtcgtt
cccctgccaggcacccacatgatctccaatgcattggcaggcgcggcagtaggctatacc
cttcatctgacttccgaagagatcaaggccggaatcgaagggctgccttccatcccggga
cgcaacaacatcatcaagacggatcgcctgatcatcctggacgactgctacaatgccaat
ccggtatccatgaaggccgctatcgacgttctggatatggccattggacgaaaagttgcc
gtccttggcaacatgggcgaacttggaaataacgagaaagtacttcaccgggaagtaggc
gaatacgctgctgcccacggcatcgacctggtatgcgggatcggccacctggcaaaggaa
ctggtagacggcgccacaaacggttcttcctctacccggggactttggttcgagaacaag
gcggactttctggatgccatgaaagatctcattaaagacggcgacaacgtactggtcaaa
gcctcccatggcatggatctgacaacgatcgtggaagcgctgaaaaatatatag
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