Cryptotermes secundus (drywood termite): 111866591 Help Entry 111866591         CDS       T07421                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism csec  Cryptotermes secundus (drywood termite) Brite KEGG Orthology (KO) [BR:csec00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:csec04040]     111866591    04990 Domain-containing proteins not elsewhere classified [BR:csec04990]     111866591 Ion channels [BR:csec04040]  Voltage-gated cation channels   Ryanodine receptor    111866591 Domain-containing proteins not elsewhere classified [BR:csec04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    111866591 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 EF-hand_1 DUF996 Motif Other DBs NCBI-GeneID:  111866591 NCBI-ProteinID:  XP_023711458 LinkDB All DBs Position Unknown AA seq 5130 aa AA seqDB search MADSEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCYLETIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETEQESLGKGTGSGHRTLLYGNAILLRHQNSDMYLA CLSTSSSNDKLAFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTAKENDLSVVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW TDQPGQNIVIYEGGSVMSQARSLWRLELARTKWAGGFINWYHPMRIRHLTTGRYLGVNEN NELYLVKKDDATLATSTFCLRQEKDDQKVVLEEKDLEVIGAPIIKYGDSTVIVQHSESGL WLSYKSYETKKKGVGKVEEKQAILHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTNF ITGLETLQLNRRASVFFHCVNLGEMVMCLEDLINYFAQPGEEMEHEEKQNRLRALRNRQD LFQEEGILNLILEAIDKINVITSQGFLVALSGDEAGQNWDVISGYLYQLLAAIIKGNHTN CTQFANTNRLNWLFSRLGSQASGEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASVRPNIFVGR VEGSAMYQKWYFEVTVDHVEQTTHMMPHLRIGWANTAGYVPYPGGGEKWGGNGIGDDLYS YGFDGASLWMGGRNTVVIPDAMEPCIKKGDVIGCALDLTVPVITFTFNGHIVKGSFRNFN LDGMFFPVISCSSKLSCRFLLGGDHGRLKYIPPEEFSPLVESLLPQQVLSIDPCFYFGNL NKVVLSGPWPVEDDTAFVPTPVDTTTVTLPSYVESIRDRLAENIHEMWAMNKIEAGWQYG ERRDDVRKIHPCLIQFERLPPAEKRYDSQLAVQTLKTILALGYYITMDKPPSRIKSLRLP NEPFLQSNGYKPAPLDLGAITLTPKMEELVDQLAENTHNLWAKERIQQGWTYGLNEDSDM KRSPHLVPYSKVDDAIKKANRDTASETVRTLLVYGYNLDPPTGEQHEALLAEAARSKHMA FRTYRVEKNYAVTTGKWYFEFEIMTAGPMRVGWARADCSPGYQLGSDEYTWAFDGYNEEK LYCGSAESFGKQWQVGDVVGVFLDLIDRTISFSLNGELLMDALGGETSFADVQGDSFVPA FTLGVGQKGKLTFGQDVNTLKFFTMCGLQEGYEPFCVNMKRPVTYWYTKDQPIFENTEDF VDTRIDVTRIPAGSDTPPCMKISHNTFETMEKANWEFLRLSLPVICQSIFIDEEEKIRRW QEIKIRQHRLLAEADQTHPAHIEQIMKSGFTMNDIKGLQRGYSEDAVEADELIMNGPSPD SPPSKLKHKPSRPPRRGSLSRNTTYDKMENMQLNGTLEPGKMQRSTSDVDLNLYNGADRM INNQESVKDDKKKRGRSPFRFFSRKRDASGDRLKKGKTPERAMDGDISPDRKPIGMGRTS TLHARTPHVRVSQTDLKIIPPSIPDRSPKVMSVPVATGLESIGNEIFDAECLRLINEYFY GVRIFPGQDPTHVYVGWVTTQYHFFSNEFNQSSVRRASVMIVDDHERILERIDRQSCYMV RADELYNEVTHDASGKGASQGMFVGCFVDTATGWITYTCEGKETSRRFKMEPETKVFPAI FVEATSKEVLQIELGRTSTTLPLSAALLQNSERHVIPQFPPRLKVQCLKPHQWARVPNQS LQVHALKLSDIRGWSMLCEDPVSMLALHIPEEDRCIDILELIEMERLLSFHAHTLTLYAA LCYQSNYRAAHALCLHVDQKQLLYAICSEYMSGPLRQGFYDLLIALHLESHATTMEVCKN EYIIPLGPELKGLYDDPEMGHSLRSLRTESVRPQMKMTDIAETVDNIKSLYSPYFPLDVV KNFVMTALDEAVQINQVHNRDPIGGSNENLFLPLLKLVDRLLLVGMLTDEDVVKLLIMID PETWDDSFQKDGKDEHRKGLLHMKMAEGAKLQMCYLLQHLCDIQLRHRVESIIAFSHDFI GDLQTDQLRRYIEIKQSDLPSAVAAKKTREFRCPPREQMNAILGFKNLEGEDRENCPCGE DLSEHLTKFHEKLMYYVSLSALQEPEEPEEPAAGAVKPGPFKRLCNIINAVKELEIEPKE EDEPQKKSPEEVFRKILISTIVRWAEESQIETPKLVREMFSLLVRQYDSIGELIRALQKT YVINSKTKDDVSQMWVGLSQIRSLLPVQMSQEEEGLMRERLWKLVNNHTFFQHPDLIRIL RVHENVMAVMMNTLGRRAQAQSDTQVQTQATGQEGEAPPKEKDTSHEMVVACCRFLCYFC RTSRQNQKAMFDHFAFLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREHYLEK IAIYLSRCGLQSNSELLEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLL IRRPECLGPALRGEGEGLLRAIIDANKMSERIADRRKLMDEAEGTMSVLQFEHPLPESDE DEDYIDTGAAILNFYCTLVDLLGRCAPDASVIAQGKNESLRARAILRSLVPLEDLQGVLS LRFTQTNPAAGEERPKSDMPSGLIPGNKQSIVLFLERVYGIETQELFYKLLEDAFLPDLR AATMLDRNDGYESDMALAMNRYIGNSILPLLIKHSSFYNEADNYANLLDATLHTVYRLSK NRMLTKGQREAVSDFLVALTSQMQPSMLLKLLRKLTIDVSKLTEYTTVALRLLMLHYDRC AKYYGSTSGQGMYGASSDEEKRLTMMLFSNIFDSLSKMDYDPELFGKALPCLTAIGCALP PDYSQSKNYDDEWYSSKTGADPDGPYNPQPINTSSVALNNDLNNIVQQFSEHYHDAWASR KLDNGWVYGEQWSDANKTHPRLKPYGMLNDYEKERYKEPVRESLKALLAIGWTVEHSDVE VPSNNRNSTRRSSKTNPVDKATPFNYHPHPVDMTNLTLSREMQNMAERLAENAHDIWAKK KKEELTTCGGAVSPQLVPYDLLTDKEKKKDRERSQEFLKYLQYQGYKLHRPNRGGGTESE QAATGAAVELRFAYSLLEKLIQYLDSASINMKLLKPSSTFSRRNSFKTSTRDIKFFSKVV LPLMEKYFSTHRNYFIAVATATNNVGAASLKEKEMVASLFCKLANLLRSRLAAFGADVRI SVRCLQVLVKGIDAKSLVKNCPEFIRTSMLTFFNNTAEDLAHTIQNLHDGRYSHLRGAHL KTSTSLFYLNGVILPVLTSMFDHLAACEYGSDLLLDEIQVASYKMLGSLYTLGTDGSLTG DRKYLKTEIERHRPALGSCLGAFSSTFPVAFLEPHLNKHNQFSLLNRIADHSLEAQDVMA RMEATMPTLEAVLTEVDQFTESEKSYADAPHVIDVILPLLCSYLPFWWSQGPDNVSPTGG THVSMVTSEHMNQLLKNVLNLIKKNIGNENAPWMTRIAAYTQQIIINSSEELLKEPFLPL AERVKKRTDNMFHKEESLRGFIKSSSDDTSQIESQIQEDWHLLVRDIYAFYPLLIKYVDQ QRNHWLKNNVVEAEDLYNHVADIFNIWSKSQYFMREEQNFISANEIDNMVLIMPTATRRS AVVSEGGQVAGGSKKKKKHRDKKRDKDKELQASLMVACLKRLLPVGLNLFAGREQELVQH CKDRFLRKLPESDIMEFAKIQLTLPDKIDPADEMSWQHYLYSKLGQKKTDEEGKPMKIDD IVERIVAMSKVLYGLHMIDHPQQQSKGSYRSVVSTQRKRAVIACFRQTSLHSLPRHRAIN IFIRTYHELWLQDENVGQEVMIEDLTQSFEDAELKKCDEVKEEGKPDPLNQLVTTFCRGA MTERSGALQEDPLYMSYAKISAKSCGEEEEEGEEEGGDEEGGASIHEQEMEKQKLLFHQA RLANRGVAEMVLLHISACKGVPSDMVMTTLQLGIAVLRGGNVDIQMGMLNHLKEKKDVGF FTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSDGAAGEKNMHDAEFTCALFRFIQLTCEG HNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKA IGVASQVFNTLTEVIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLK ELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLTSS ASFQEIDVNHDGWVFPKDFREKMEQQKSYTPEEINFLLMCCDTNHDGKIDYVEFTDRFHD PAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGGSKRIERVY FEIKESNIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMAV VESSGGGKAREASYSYMTEEDEERAAKDPIQRGIQTTKDTLYFCMAMLSPSHIKAKINEL QQMTIPEIFIAFFKMIFYSFYYSGFGVSIVIRYIVGILMSLMRGPQIEEPVAEVKEEEKL GPVRMLPALPATPDEASSPTQLQAFGLDITKEDNGQFHMAPHESAPPSPQSSLEEGGEST PEEGGEEHPKPEGAEGEPPLSLVDLLGGDAARKAAAATAEAAAQQQAVMAAVEAETKQEV VVEPAAVSQIDFSEYTARAVSFLARNFYNLKYVALVLAFCINFILLFYKVTTLGDDGDDG DDGSGSGEDLADLMDELSAEVNSTEVLSGEESGGQDDEEEDPIELVHVDEDFFYMAHVMR LMAALHTLVSVAMLIAYYHLKVPLAIFKREKEIARRLEFDGLYIAEQPEDDDIKSHWDKL VISAKSFPVNYWDKFVKKKVRQKYSETYDFDSISNMLGMEKTSFSAQEEETGSGFIHFIL NIDWRYQVWKSGVTITDNAFLYSLWYFIFSILGNFNNFFFAAHLLDVAVGFKTLRTILQS VTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYVQEEDEEVDKKCHDMLTCFVFHLYKG VRAGGGIGDEIEPPDGDDYEVYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQLDSV KENMESNCFICGIGKDYFDTVPHGFDTHVAKEHNLANYMFFLMHLINKPDTEYTGQETYV WNMYQQRCWDFFPVGDCFRKQYDELGGGGG NT seq 15393 nt NT seq  +upstreamnt  +downstreamnt atggctgacagcgaaggaggctcggagcaagatgatgtttcatttcttcgaacagaagat atggtgtgcttgtcatgcacagccaccggtgaaagagtgtgcttggcagccgaaggcttc ggcaacagacattgttacctggaaaccatagcagataagaacatcccacctgacctgtca caatgcgtgttcgtaatagaacaagccttgtcagttcgcgctcttcaggaactagtcacc gctgccggctcagagacggaacaagaatctctcggtaaaggtactggatcaggccacaga actctgctatatggcaatgccattcttcttcgacatcagaatagtgatatgtatttggcc tgtttatcaaccagctcttccaatgataaattagcctttgatgtgggtctccaggaacat tcccaaggtgaagcctgttggtggactgttcatcctgcatcaaaacaaagatctgagggt gagaaagtgagagttggtgatgaccttattttagtgtctgtagccacagagcgatatcta catacagcaaaagaaaatgacttgtctgtagtgaatgcatctttccatgtaactcattgg tctgtgcaaccatatggaactggcattagcaggatgaagtatgtaggttatgtctttggt ggtgatgtattaaggttcttccatggaggtgatgaatgtctcaccattccatctacttgg actgatcaacctggtcaaaatattgttatttatgagggtggcagtgtaatgagtcaagcc agatcactgtggcgacttgagctggctagaaccaaatgggctggtggcttcatcaactgg tatcatccaatgagaatccgtcatcttaccactggccgatatttgggagtaaatgagaac aatgagctgtatctggtaaaaaaagatgatgctacacttgccacatccacattctgcctg cgacaagagaaagatgatcagaaagtggtcctggaagaaaaagacctggaagttattggt gctcccatcatcaagtatggtgatagtactgtaattgtacaacactcagaatcaggactg tggctgtcatataagtcttatgagacaaaaaagaaaggagttggtaaagttgaggagaag caagctatactccatgaggaaggaaagatggatgatggcttagatttcagccgcagtcag gaagaagaatcaagaacagctcgtgtgattcgaaagtgcagttccctcttcaccaacttt atcacgggcctggaaactctacagcttaacagacgtgcatccgtgttcttccactgtgtg aatttaggtgaaatggtgatgtgtcttgaagatctgattaactattttgcacaacctgga gaagaaatggaacatgaagagaaacagaatcgtcttcgtgccctaaggaatcggcaggac ctattccaagaagaaggcatactgaacctaattctagaagccattgacaaaattaatgta ataacctctcaaggttttctggtggctttgtcaggtgatgaggcaggccagaattgggat gttatttctggatacttgtatcaattgcttgctgcaatcatcaagggaaatcacactaat tgtacccagtttgcaaacacaaacagattgaactggttgtttagcagattgggctcacag gcttctggtgaaggtactggaatgttggatgtgctgcattgtgtgctaattgactctcct gaagctctgaacatgatgagggatgagcacattaaagttattatctccctactggagaag catggccgagatccaaaggtccttgatgtgttgtgctcattgtgtgttggtaatggtgtt gcagtcagaagttcacagaacaacatatgtgatttcttgctgccaggcaagaatttgctg ctgcagacacagctggtggaccatgttgcaagtgtgagaccaaacatctttgtgggacga gtagaaggatctgctatgtaccagaagtggtattttgaagtgacagtagaccatgttgaa cagacaactcatatgatgccacacctaaggattggctgggccaacactgctgggtatgta ccttatccaggtggaggtgagaaatggggtggcaatggtatcggtgatgacttgtattcc tatggttttgatggtgcaagcctttggatgggtggccgcaatactgttgtgataccagat gcaatggagccttgtatcaagaaaggagatgtgattggctgtgcactggatttaacagtt ccagtaataacattcacattcaatggacacattgtgaaaggatcattcaggaattttaac ttggatggcatgttcttcccagtaattagctgctcttccaaactaagctgccgatttctt cttggtggtgaccatggccgcttgaaatacattcctcctgaggaattttcaccactagtt gaaagcctgctgccacaacaagtgctctcaattgatccatgtttttattttggaaatctt aacaaggttgtcctttctggaccttggcctgtggaagatgatactgcatttgtgccaaca cctgttgacactacaactgtaacacttccaagttatgtggagagtataagagaccgtcta gcagaaaacattcatgaaatgtgggctatgaataaaattgaagctggttggcagtatggt gaaagacgagatgatgtgaggaaaattcatccgtgtctcattcagtttgagcggttacca ccagctgagaaacgttatgactcccagcttgcagtacaaacattgaaaactatattggca ttgggatactacataacaatggataagcctccatctcgaataaaatctcttcgtcttcca aatgaaccatttctacagtccaatggctacaaaccagctccactggatcttggtgccata acgctcactcctaagatggaagaactggtggaccaattggcagagaatacccataatctg tgggcaaaggaacgaattcagcagggatggacttatgggttaaatgaggattccgatatg aagaggagtccgcatctggttccttacagtaaagtggatgatgctatcaagaaagcaaac cgggacactgcaagtgagacagttcgaacattgttggtatatggttacaaccttgatcct ccaactggagagcaacatgaagccttacttgctgaagcagcaagaagtaagcatatggca ttcagaacctacagagtagagaaaaactatgcagtcactacaggaaaatggtactttgaa tttgagatcatgactgcaggcccaatgcgtgttggatgggcacgtgctgattgcagtcca gggtatcagttgggcagtgatgaatatacatgggcatttgatggatataatgaagaaaag ctttattgtgggtcagctgagtcatttggcaaacaatggcaagtgggagatgtggtcgga gtattcctcgacctaattgatcgtactataagcttctcactaaatggtgagcttttaatg gatgccctgggcggtgagacatcatttgcagatgttcagggtgattcatttgttcctgct tttacattgggagttggccaaaaaggcaagcttacatttgggcaggatgtaaacacgctg aaattcttcaccatgtgtggccttcaagaaggatatgaacctttctgtgtcaatatgaag agacctgtaacatactggtacacgaaggatcagccaatatttgagaacactgaagacttt gttgacacaaggattgatgtgacaagaataccagcaggatcagatacaccaccttgtatg aagattagtcataatacttttgagaccatggaaaaggctaactgggagtttctcagactg tcattacctgtcatatgtcagtcaatattcatagatgaggaagaaaaaatcagacgatgg caagagattaagattcgccagcatcgacttcttgctgaggctgatcagacgcacccagca catatagaacagatcatgaagtctggtttcacaatgaatgacattaaaggtcttcagcga gggtattcagaagatgctgttgaagcagatgaactcataatgaatggaccatcgccagat tctcctccaagcaagctgaagcacaaaccatccagaccgcccaggagaggctcactttct cgaaacaccacatatgacaaaatggaaaatatgcaactgaacggaacattagaaccaggt aaaatgcaacgatccacaagtgatgtagacttaaacctgtataatggtgcagatcgaatg atcaataatcaggaatcggtgaaagatgataagaagaaacgaggacgttctcctttcaga ttcttctctcgtaagcgtgatgccagtggtgatcgtctgaagaaaggaaaaactccagaa cgagctatggatggagacataagtcctgatagaaaacccattggtatgggccggactagc acactacatgcgcgaacaccacacgtgagagtctcacagacggatttaaaaattattccg ccttccatcccagatagaagtccaaaggttatgtctgtcccagttgccacaggattagaa tctattggcaatgagatcttcgatgctgaatgtctcagacttataaatgagtacttctat ggtgtgaggatcttccctggacaagacccaacacatgtctatgtgggctgggtgacaaca cagtatcacttcttcagcaatgaattcaatcagagcagtgttcgcagagcttctgttatg attgtagatgaccatgaaaggatacttgaaagaattgatcgtcagagttgctacatggtc cgagctgacgaactgtacaacgaagtaactcatgatgcatcaggcaaaggggcatctcaa ggaatgtttgttggttgctttgttgacacagcaactggctggatcacctacacttgtgaa ggaaaggaaaccagccgcaggttcaagatggaacctgaaacaaaagttttccctgccatc tttgtggaagcaactagcaaagaagttttgcaaattgagttgggtagaacatcaaccact ctacctctttcagcagctctgcttcagaattctgagaggcatgttataccacagtttcca ccaagacttaaggtgcagtgcttgaaacctcaccagtgggcacgagttcctaaccagtcc ttgcaagtacatgccctgaaactgtcagacattcgtggttggagtatgctttgtgaagac cctgtgtccatgttggcacttcacattccagaagaagataggtgcattgacatattagaa ttaattgagatggaacgtctgctgagttttcatgcccacactcttaccttgtatgccgca ctctgctaccagtccaactatcgtgcggctcatgccctctgtctccatgtagaccagaaa cagcttttatatgccatatgttcagagtacatgtcggggcccctgcgacagggcttttat gatttgctcattgcactccatttggagtcacatgctacaactatggaagtttgtaagaat gaatatatcattccattgggtccagagttgaagggattgtatgacgatcctgaaatgggt cacagtttacgttcactcagaacagaatcagtgagaccacagatgaagatgaccgacatt gctgagacagttgacaacatcaagagcctgtacagtccctatttccctctggatgtggta aagaattttgtaatgacagctttagatgaggctgtgcaaataaatcaggtacacaacagg gatcccattggaggcagtaatgagaacctcttcctacccttattgaaattagtggatcgt ttgttactggttggaatgctgactgatgaggatgtcgttaagttgctcatcatgatagac ccagagacgtgggatgactcattccagaaagatggtaaggatgagcataggaagggcttg ctacatatgaagatggctgaaggagctaaacttcagatgtgctacttacttcagcatctt tgtgatattcagttgcggcacagagtggaatccattattgccttcagtcatgacttcatt ggtgatttacaaactgatcaacttagaagatacattgaaatcaagcaatctgacttgcca tcagctgttgcagctaaaaagaccagagaattcagatgtccacctcgggaacaaatgaat gcaattcttggcttcaagaacttggaaggagaagacagggaaaactgtccctgtggagaa gacctgagtgagcacctgacaaagtttcatgagaaacttatgtattatgtttcactaagt gctttacaggagcctgaggaacctgaggaacctgctgcaggtgctgtaaagcctggacca tttaagcgtttgtgtaatattataaatgctgtgaaagaattggaaatagagcctaaagaa gaggatgagccacaaaagaaatcacctgaagaggtattcagaaagatactgattagcacc atagtaagatgggctgaggagtcacagattgaaacacctaagcttgtacgagaaatgttc agcttgttggttcggcagtatgacagcattggtgagctcattagagcactgcagaaaaca tacgtcattaacagtaagacaaaggatgatgtttctcaaatgtgggtcggtttaagtcag ataaggtctctcttacctgtgcaaatgtcgcaagaagaggaggggcttatgagagagcga ctgtggaagctggtgaacaaccatacattcttccagcatcctgacttgataagaatctta cgtgtccatgagaatgtgatggcagtgatgatgaatactcttggcagacgagctcaggcc caatcagatacccaagtacaaactcaagccacaggccaagaaggagaagcacctccaaag gagaaggatacctctcatgagatggtggtagcttgttgccgattcctgtgctacttctgc agaacttcacgccagaaccagaaagccatgtttgaccatttcgcatttcttttggagaac agtaacatccttctgtcaagaccatctttgcgtgggagtacacctctagatgtggcttat tcctccctgatggagaatactgaacttgcactggcacttcgagaacactacttggaaaaa attgctatctatctttctcgttgtggtttacaatccaactcggagcttcttgagaaaggc tatccagacctaggttgggatccagtggaaggagagagatatttggatttcttacgattc tgtgtctgggtcaatggtgagagtgtggaagaaaatgccaaccttgtaattcgtcttctg atccgtcggccagaatgcttaggtcctgcactgagaggtgaaggagaaggattgctgaga gccatcattgatgccaacaagatgtcagagcgcatagctgacagaaggaagttgatggat gaagcagaaggaacaatgtcagtactgcagtttgaacatccactgccagagagtgatgaa gatgaagattacattgacactggagcagccattcttaacttctactgtactttggtggat cttcttggtcgctgtgctccagatgcttctgtcattgcacaggggaaaaatgagtctctc cgagcaagagccattctgcggtcactggtgcctctggaagatctacaaggggtactgagt ctgaggttcactcagacaaatcctgcagcaggagaggaacggcctaagagtgacatgcca tctggtctcattcctggcaataaacagagtatagttctcttccttgagagagtgtatggt attgagactcaagaattgttctataagctcctggaagatgcgttccttcctgatctccga gcggccaccatgttggacaggaatgatggctatgaatctgatatggcattagcaatgaat cgttacattggcaattccatcttgccacttcttatcaaacactcttcattctacaatgaa gctgataattatgccaatttattggatgccaccttgcatacagtttataggctgtccaaa aacagaatgcttaccaagggtcagagagaagctgtatcagactttctcgtggcacttacc agtcaaatgcaaccaagcatgttactgaagttgttgaggaaactaaccattgatgtttcc aagctgacggagtacaccacagtagcactgaggttgctgatgctgcattatgacaggtgt gccaagtattatggttctacatcaggacaagggatgtatggtgcttccagtgatgaagag aagaggttgactatgatgctcttcagcaacatctttgattctctctctaaaatggactat gatccagagctgtttggaaaagcacttccatgcttgactgccattggttgtgctctgcca ccagactactctcagtccaaaaactatgatgatgaatggtacagctcaaagacaggtgca gatcctgatggtccttataacccacagcctatcaacaccagcagtgtggccttaaacaat gatctcaacaatattgttcagcaattctcagaacattatcatgatgcatgggctagtagg aaactggataatggttgggtgtatggagagcagtggtctgatgctaacaagactcaccct cgcttgaaaccatatggcatgctgaatgactatgagaaagagcgttataaggaacctgtg agagagtccttgaaggccctgcttgctattggttggactgtagagcactctgatgttgaa gtaccatcaaacaatagaaattccacaagaagatcatccaaaacaaaccctgttgacaaa gcaacgccatttaactaccaccctcacccagtagatatgactaacctcactctaagcaga gagatgcaaaacatggctgagagattggctgaaaacgctcatgatatctgggcaaagaag aagaaggaagagctcacgacttgtggaggagctgtcagtccacagttggtgccatatgat ttgctgactgacaaggagaagaaaaaggacagagagcgttcacaggaattcctcaaatat ctacagtaccaaggctacaagctacacaggcccaaccgtggtggtggaactgaatcagaa caagcagctacaggagctgcagtggaactaaggtttgcatacagcctgctggaaaaactt atacagtacttggactcagcttccatcaatatgaaacttcttaaaccatcaagcactttc agtagaagaaacagcttcaaaacttccacaagggacattaaatttttctcaaaggtggtg ttgccgttgatggaaaaatatttcagcactcatagaaattacttcattgctgtagcaact gctactaacaatgtaggggctgcatctctgaaggagaaagaaatggtggccagtttgttt tgcaaacttgccaacctgctacgttcccgcctggcagcatttggagctgatgtgcgcatt agtgtcagatgtttacaagtgttagtaaagggaattgatgccaaatcactggtgaagaac tgtccagaatttattcgtacatcaatgttgactttcttcaataacacagcagaagatctg gcacacactatacagaatctgcatgatggccgttacagccatttgaggggcgctcacttg aaaacgtctacatctctgttctacttaaatggtgtcattctaccagttctgacctccatg tttgatcatctagcagcttgcgagtacggaagtgatctactattggatgaaatccaagtg gcttcttacaaaatgctgggcagtttatatacattggggactgatggatctttgacagga gacaggaaatatttgaagactgaaattgagaggcatcgtcctgctcttgggagctgccta ggagctttctcctcaacattcccagttgctttcttagagcctcatctcaacaagcacaac cagttctcccttctcaaccgcattgcggatcattccctggaggcacaggatgtgatggcc aggatggaggctactatgccaacactagaggctgttctcacagaagtggaccagtttact gaatcagagaaaagttacgcagatgctccccatgttattgatgttattctacctttactt tgttcataccttccattctggtggtcacaaggaccagacaatgtcagccccacaggagga acacacgtgtccatggtgacaagtgaacatatgaaccagttactgaagaatgttctgaat cttatcaaaaagaacatcggtaatgaaaatgctccatggatgacaaggattgcagcatac acacagcaaattatcatcaattcatctgaagaactgctgaaagaaccattccttcctttg gctgaacgtgtaaagaaacgaactgataatatgttccacaaagaagaatcactgagagga ttcattaagtcatcctctgatgacacttctcagattgagtctcaaattcaggaagactgg cacctgctagtgagagacatctatgccttctatccacttcttatcaagtatgttgatcag caacgtaaccactggctgaagaacaatgtggtggaagctgaggacctatataaccatgtt gcagacatcttcaacatttggtccaagtcacaatactttatgcgtgaggagcagaatttc atatccgctaatgagattgataacatggtactgatcatgcctacagcaactcgcagatcc gctgttgtttctgaaggtgggcaagttgctggaggaagtaagaaaaagaagaaacatcgt gataagaagcgtgataaagataaggaactgcaggctagtttgatggttgcctgtctcaag agacttctgccagttggtctcaacctttttgctggtagagaacaggaattggttcagcac tgcaaggatcgtttcctcaggaaactgccagagagtgacataatggaatttgccaaaata caacttactcttcctgataagattgatccagcagatgaaatgtcatggcaacattatctt tactccaagcttggacagaagaagactgatgaggaaggcaagcccatgaaaatagatgac attgttgagaggattgttgcaatgtcaaaggttctatatggactgcacatgattgaccac cctcagcaacaaagtaagggcagctatcgttcagttgtttccacgcagaggaagcgtgct gtcattgcctgcttccgacaaacatcactgcattccctgccaaggcatcgggcaatcaac atttttattcgaacataccatgaactgtggttacaagatgaaaatgtgggccaggaagtc atgattgaagatctcacacaatcatttgaagatgcagagttgaagaaatgtgacgaggta aaggaagaaggaaaaccagatcccctgaaccaacttgttaccacattctgccgaggggca atgacagagcgcagtggagctttgcaagaggacccactgtacatgtcatatgctaaaatc tctgcaaagtcatgtggtgaggaagaagaggaaggagaagaagaaggtggggatgaagaa ggaggtgcttccattcatgaacaagaaatggagaagcaaaagttactgttccatcaggca aggttagcaaacaggggtgtggcagaaatggtactcctccacatctcagcatgcaaaggt gttcctagtgacatggtcatgacaacactgcagttgggcattgcagttcttcgaggaggc aatgttgacattcaaatgggaatgctgaatcaccttaaagaaaagaaggatgttggtttc tttacttccattgctggtctcatgaattcttgtagtgtgctggatctggatgcctttgaa cgcaataccaaggcagagggtctgggtgtaggttcagacggagcagctggagagaagaac atgcatgatgctgaatttacttgtgctctcttcaggttcattcaactgacctgtgaaggt cacaatcttgagtggcagaattatctgagaactcaggctgggaacacaactacggtcaat gttgttatctgcacagttgattacttgctaaggcttcaggaatctatcatggatttctac tggcattattctagtaaagagatcattgatccagccggaaaagcaaatttcttcaaagct attggggtagcaagtcaggtatttaacacacttactgaagtgatccagggtccatgtaca cagaatcagcaagccttagctcactcaaggttgtgggatgctgttggaggtttcttgttt ctcttctcacacatgcaggacaagctatcaaaacattcaagccaggtagacttactgaaa gaacttctcaatcttcagaaggacatgataactatgatgctgtctatgcttgaaggcaac gttgtcaatggcacaattggtaaacagatggtggacaccttggtagagtcagcatctaat gttgagttgatcctgaagtactttgacatgttcttgaagctcaaagatttaacatcatca gctagcttccaggaaattgatgttaaccatgatggatgggtttttccaaaggatttcaga gaaaaaatggagcaacaaaagagctatactcctgaagagatcaacttcttgttgatgtgt tgtgatacaaaccatgatggtaagatagattacgtagaattcacagataggttccatgat cctgccaaagaaattggcttcaaccttgctgtactgcttaccaacttgtctgagcacatg cctaatgaaccaaggttggccagattcttggaaacagctggcagtgtcctcaactacttc gaaccattcctagggcgtattgaaatccttggtggcagcaagaggatagagagggtgtac ttcgaaatcaaggaatctaacattgaacagtgggaaaagccacaaattaaggaatcgaaa cgcgcattcttctactccattgttactgaaggaggtgataaggagaagttggaagcattt gtgaatttctgtgaggatgccatttttgaaatgacacatgccagtgggctgatggctgta gtggagagctctggaggaggaaaggcaagggaagcctcatacagttacatgacagaagaa gatgaagaacgcgctgctaaggaccccatccaacgaggcatccaaactacaaaggatact ttgtacttctgtatggcaatgctgtctccatcacatatcaaagcaaagatcaatgagctg caacagatgacaataccagaaatcttcattgcctttttcaagatgattttctattctttc tattactctggatttggtgtctcaattgtcatacggtacattgtgggaattctgatgtcg ttaatgcgaggtccacaaatagaagagccagtggcagaagtgaaagaggaggaaaagcta ggcccagtacgaatgttaccagcattaccagcaacacctgatgaagcttcatcaccaaca cagttgcaggcatttggactcgatatcaccaaggaggacaatgggcagttccacatggcc ccacatgaaagtgctccaccatcaccacagtcaagcttggaagaaggtggggagtctacc ccagaagaagggggagaagagcatccaaagcctgagggcgctgaaggagaacctccattg tctctagttgacttacttgggggtgacgcagctcgtaaagctgctgctgcaacagcagag gcagcagcccagcagcaggctgtgatggcagcagtagaggcagaaacaaaacaggaagtt gttgtagaaccagccgctgtgtcccaaattgacttcagtgagtacacagcaagggctgtt agtttcttggctcgaaatttctacaacctcaagtatgtggctttagtattggctttctgc ataaacttcattctactgttctataaggtaacaactcttggtgatgatggtgatgatggt gatgatgggagtggttctggggaagacttggctgatttgatggatgaattgtctgctgaa gttaattcaacagaagttctgagtggagaggaaagtggaggacaggatgatgaagaggaa gatcctatagaattggtccatgttgatgaagatttcttctatatggcacatgttatgagg ttaatggcagcattacatacgcttgtgtccgtggccatgcttattgcatattaccatctc aaggtgccattggctatattcaagcgagagaaggagatagcaaggcgactggaatttgat ggtttatatatagcagagcaaccagaggatgatgatatcaagtcacactgggataagcta gtcatatcagcaaaatcattccctgttaactattgggataaatttgtgaagaagaaggta cgccaaaaatatagtgagacttacgactttgactcaattagtaatatgctgggaatggag aaaacatctttcagtgctcaagaggaagagacaggaagtggctttatacatttcatcttg aatattgactggaggtatcaagtttggaagtcaggtgtcacaatcaccgacaatgctttc ttgtacagtttatggtatttcatattctccatccttggaaacttcaataacttcttcttt gcagcccatttgctcgatgttgctgtaggtttcaagacattgcgcactattctgcagtca gtaacacataacgggaaacagcttgtgctaacggtaatgctgctgacaataattgtgtac atatacactgttattgccttcaacttcttcagaaagttttatgtgcaagaggaagatgaa gaggtggataagaaatgtcatgacatgttaacttgctttgtattccatttatacaaagga gtacgtgctggtggaggcattggtgatgaaattgaacctccagatggtgatgactatgaa gtatatcgtattctctttgatatcactttcttcttctttgtcattgtcattctgcttgct attattcaaggtttgataattgatgcttttggtgagctgagagatcagttggatagtgtg aaagaaaatatggaatccaactgctttatctgtggcattggcaaagactactttgacaca gtaccacatggttttgatacacatgtcgcaaaggagcacaatctagccaattatatgttc ttcctgatgcatctcatcaacaaaccagatacagagtacacaggtcaagagacatatgtg tggaacatgtatcaacagaggtgctgggacttcttccctgttggtgactgcttcaggaag caatatgatgaattaggaggtggtggtggctaa

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