KEGG   Cynoglossus semilaevis (tongue sole): 103383928
Entry
103383928         CDS       T04866                                 
Symbol
tsc2
Name
(RefSeq) tuberin isoform X1
  KO
K07207  tuberous sclerosis 2
Organism
csem  Cynoglossus semilaevis (tongue sole)
Pathway
csem04115  p53 signaling pathway
csem04140  Autophagy - animal
csem04150  mTOR signaling pathway
csem04218  Cellular senescence
csem04910  Insulin signaling pathway
csem05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:csem00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    103383928 (tsc2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103383928 (tsc2)
  09143 Cell growth and death
   04115 p53 signaling pathway
    103383928 (tsc2)
   04218 Cellular senescence
    103383928 (tsc2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    103383928 (tsc2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    103383928 (tsc2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:csem01009]
    103383928 (tsc2)
Protein phosphatases and associated proteins [BR:csem01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     103383928 (tsc2)
SSDB
Motif
Pfam: Tuberin DUF3384 Rap_GAP HEAT
Other DBs
NCBI-GeneID: 103383928
NCBI-ProteinID: XP_008315481
LinkDB
Position
9:12633643..12653968
AA seq 1868 aa
MNKQPSKESLKDKVKGIFGLGPARPPSRQSDSKSSEIIITNDIIKELHPDCGLNTRIRMI
NYVCELAKTKKFEEHAVETVWKSVEDMLVPEQPPEARHAVLQLLKAIIQGQGEHFGPLRA
YFFKVIRDYQPSNEDLSYRLDVFKALTEDGKDITYLEEDIAFFVLLWMDIGLTSDFLHVL
VNLVKFNSCYLDQNVSVMVQKICLLCNRTISSTDIEVALQVLDAVVCYNCLPSDSLIVFI
ITLCRTVNVKEFCESCWKLMRKVLGTHLGHSAIYTMCRIMEERVYMEDAPLLRGAVFFVG
MALWGAHRLPALKNTPTLVLPSFYKAMSCANEVVSYEIVLSITRLIKKYGKELQVVTWDI
LLGIIERLLQQIQTIGSAELKVIVYELLTTVEELYDQNDYHGSTEKFFSLVEKCADKRPD
ASVLTLISYRAQSIQPAKDGWIQSLYHLMEKFFKNETRSVIRIKVLHILSFVLSTNRQLY
EDELIEIVVIPLLSGIAEDRDLAVRKQATQLLVDLAEGCNTHHFTSLLDIIERVASCSLV
CSETPEFSERDPTLESPVEDVRTAVLGLLEILQSKLYSLPVSHASRVYELLINHLQLHYR
NKYCSAIASSIRLQVFDFFLMMRADSLHRLGVPNKDGVIRFSPYCYCDTGETEKRVNEKK
TIGTTSPPADRAATLAPPLSASSVRSAYLPYAPAFSVILQCLKMEVDWKVLKLVLDKLPW
TLQYKVLLLTSPCSLDLLCSNLCYMVTDRLISERLKKTPEGFSRTDVQLAVVPVLTALTS
YHNYLEQSRQRELVQCLETGLIYRCAKQCVVALTMCTVEMPDIMIKLLPAFIVKLTHISA
TVAMASPMLEFLSTLVRLPHLYANFVAEQYVSVFAISLPYTNPSKFNQYIVSLAHHVIAM
WFIRCRLPFRKDFVQYITKGLRSNALLPFDDSHEQSPFRARSTSLNERPKSLRAAKVANA
AAAVANSSGSPVKELRDLSAIDAFRSRSISVSEHAVRRMHTSTTTCSLGAADENAVTQAD
EGLKTVHLELTETCLDMMARYVFSNFSALPKRSPIAEFLLAGGRSMTWLVGNKLVTITTS
AGVRTQALLGLDMAERLAGGVGELTRSDPSLHTRITKEAPAKLESQSSQQNRAARIRVRS
MSGGHALRTGPLQSLSPLVSSFEGELAAPPSHCSGPTLDPLGTPPCTSATSSVPSPFKDN
PSLADFVPILTQGWAEIFIRRPSGNTSWLMCLENPPSPFSSEIGNIPLQELSSVLMAMKG
VKEPPTQTSSDPTSTAAPAPTQLSDSPTQTYSSAGGKAHLIQRSNTESVVVLEGSGVKAS
AHTTSDWVESKDFEPLTTDPIFKSADSFTKTPATLSRSSSTSSQDGDKSTLEEISEGAIP
IDLPTPGTFTPGKQGSELSFQTHSQSQGHGLNKSSSSPELQTLPEAFTKGVIESETVLPD
TSRPRAPSVGKLQCQQPHFENEKLEINTVDKINGSGGQTQNTEGPGAPSAQSGGAGLRLE
FPAAAQPGPVSPGGGHRPRGHTISVSAPSSRRERRNERDSYLNRPGSSNAEKLSGLSPSF
VFLQLYHSPFFGNEANKPLLLPKTQVIDRAVKVLDQMPPYDTHKIGVVFVGAGQVNNEVA
ILSNEYGSNRYTGFLTGLGKLIHLKDCDPDQIFLGGLDQYGDDGEFTYCWHDDIMQAIFH
IATLMPNRESDKGCCNKKRHIGNDFVMVVYNDSGEDYKLGTIKGQFNFVEVIIKPLDYEC
NLVTLQCRKDLEKLVDTSVAKIISDRNLPLLVRQMALHANMASLVHQYRANPSDAYASKW
LARLRHIKRIRTRAQEDIQSRSTPSISLTQVHSQQNKSFQQSAPAPNPETSGQRKRLVST
VDDFTDFV
NT seq 5607 nt   +upstreamnt  +downstreamnt
atgaataaacaaccgagcaaggagagcctgaaggataaggtgaaggggatatttgggcta
ggtcctgctcgcccacccagtcgacaaagtgattcaaaatcatctgaaattataatcaca
aatgacatcataaaggagctacacccagattgtggtctcaatacaagaattcgtatgatt
aactatgtctgtgaacttgccaaaacaaaaaaatttgaagagcatgcagttgaaactgta
tggaaatcagttgaggatatgctggttccagagcagccacctgaagcccgacacgctgtc
ttacagcttttaaaggctattatacagggacagggagaacactttggtcctttgagagct
tattttttcaaagtgatcagagactaccaaccaagcaatgaagacctctcctataggctg
gatgttttcaaggccttaacagaagatggaaaagatatcacatatcttgaggaagacata
gccttctttgtcctcctgtggatggacataggtctcacatcagactttctccatgttctt
gtaaacctggtgaagttcaatagctgctacctggaccaaaatgtgtcagtcatggtccag
aaaatttgtcttttgtgcaatagaacaatatcatccactgatattgaggttgcgcttcaa
gtactggatgctgtggtgtgttacaactgcctgccttcagactctctcattgtctttatc
atcacactctgtcgaaccgtaaatgtcaaggagttttgtgagtcttgttggaagctgatg
aggaaggtgttagggactcatctaggccacagtgccatttacactatgtgccgaatcatg
gaggaaagggtgtacatggaggacgctccattgttgagaggagctgtattttttgttggc
atggcactttggggggcacacagactccctgccctcaaaaacacacccacactggttttg
ccatccttttataaggctatgtcgtgtgccaatgaggtggtttcctatgaaatcgtcctc
tccatcaccaggctaatcaaaaagtatggcaaggaacttcaggtggtcacctgggacatc
ctgctggggatcattgaacgactgctgcagcaaatccagacgataggcagtgctgagtta
aaggtcattgtctatgagctgttgaccacagtggaggaactctatgaccagaatgattac
cacgggtccacagagaagttcttcagtctggtggagaaatgtgccgacaaaagacctgat
gcatcagtgctgaccctcatctcatatagagcccagtccatccagccagccaaggatggt
tggattcaaagcctttatcatctaatggagaagttttttaagaatgagactcgcagtgtt
ataaggattaaagtgcttcacatcctgtccttcgtcctcagcaccaacagacagctgtac
gaggatgagttaattgaaatagtggtaattccactgctcagtggtatagctgaagaccgg
gacctggctgtcaggaaacaagccacacagctgcttgtagatcttgccgaaggatgtaac
acacaccatttcaccagcctgctggacatcatcgagcgagtggctagttgctctctggtg
tgttcagaaacccccgagttttctgaaagagacccaacactagagtctcctgtggaggat
gttaggacagctgttcttggcctactggaaatcctgcagagcaagctctacagtcttcct
gttagccatgcaagtcgtgtttatgaattactcatcaaccacctgcagcttcactacaga
aacaagtattgttcagctattgcctccagtattagactacaggtatttgacttcttcctg
atgatgcgtgcagactctctgcatcgtcttggcgttcccaacaaagatggagtcattagg
tttagcccttactgctactgtgacacaggggaaacagaaaaacgagttaatgaaaagaag
acaatcggcacaacatctccgcctgctgaccgtgcagccaccctggctcctcctctttca
gcatcctcagtacgctcggcctatctgccgtatgcaccagccttcagtgttattcttcag
tgcctgaagatggaagtggactggaaggttctgaagctcgttcttgacaagctgccatgg
accctgcagtataaagtgctgctactgacatcaccgtgcagcttagatcttctctgttca
aatctctgctacatggttactgatcgtcttatctcggagcgtctaaaaaagactcctgaa
ggattttcccgcactgatgttcaacttgcagtggttcctgtcctcacagctcttacctcc
taccataattatctagagcagtcaagacagagggaactggttcagtgtcttgagactggc
ctcatttaccgttgtgcaaagcagtgtgtagtggccctgacaatgtgtacagtggagatg
cctgacatcatgattaagcttcttcctgcgttcatagtcaagctcacccatatctctgcc
actgttgccatggcatctccaatgctggagtttctgtccactttggtgcgcctcccccat
ctctatgccaactttgtagccgagcagtacgtcagtgtgtttgccatctctctaccctac
accaatccatcgaagtttaaccagtacatcgtatctctggctcatcatgtgatcgcaatg
tggttcatacgctgcagactacccttccgtaaagactttgttcagtatataactaagggt
ttgcgttccaacgcccttttgcctttcgacgacagtcatgagcagagtccatttcgtgcc
aggagcaccagcctcaatgaacgacccaagagtctacgggcggcaaaagtggcaaatgca
gcagcagcagtagccaatagcagcggctctcctgttaaagagctgagggacctgtcagcc
atcgacgctttccgctcccgcagcatcagtgtctccgaacatgctgtccgaaggatgcac
acttcaaccactacatgcagcctcggtgccgctgatgaaaatgcggtgacccaggcagat
gaggggctgaagactgtacacctggagctcactgaaacctgtcttgatatgatggcacga
tacgttttctccaacttctctgcactgccaaagagatctccaattgcagagttcctgttg
gctgggggtcgcagtatgacctggcttgtgggcaacaagctggtgactataacaactagt
gcgggggtcagaactcaggcactactgggtttggacatggctgaacgactggcaggagga
gtgggggaacttacaaggtcagatccgtcactacacactcgaattaccaaagaggctcca
gctaaactggagtcacagtccagccagcagaacagagctgcacgcatccgcgttcgctcc
atgtcaggggggcatgctctacgcacaggtcctttgcagagtctgagtcctcttgtgtca
tcatttgagggggagttagctgcccctccctctcactgctctggtccgacccttgatccc
ctgggcactcccccctgcacctctgctacatcctcagttccgtcacctttcaaagacaac
cccagtctggctgactttgtccctatactcacgcagggttgggcagagatcttcatccgc
agaccatctggtaacacgagctggctgatgtgtctggagaatccacccagtcccttctcc
tctgagattggcaacatacctctgcaggagctctccagtgtcctgatggccatgaaagga
gtgaaagaacctccgacccagaccagtagtgatcccaccagcacggcagctcctgcacca
acacagctgtctgattccccaacccaaacgtacagcagtgcaggaggaaaggcacatctg
atccagcgctcaaacacagagtcggtggtggtgttggaggggtcaggagtcaaagcatca
gcacacacgacttctgattgggtggagagcaaagacttcgagccactgactactgatccc
atttttaagtctgctgacagtttcaccaagactcccgcaacacttagcaggtcatcctcc
acctccagtcaggatggtgataagtcaacactggaagaaataagtgagggagcgattccc
attgatctgcccaccccaggaactttcaccccagggaaacaggggtctgagctttctttt
cagactcactctcagtcccagggtcatggactcaacaagtccagctcctcacctgaactg
cagacattacctgaagccttcaccaagggagtgattgagtcagagacagtgttgccagac
acctcacggccaagagcgccttcagttggcaaacttcagtgccagcagcctcactttgaa
aatgagaaattagaaataaacacggtagataaaataaatgggtcaggaggtcaaacccaa
aacaccgaaggtccaggtgcaccttctgcacagagtggaggcgcagggttgaggttggag
tttccagcagcagcacaacctggacctgtctcccccggtggaggccaccgtcctcggggt
cataccatttcagtatcagccccctcctccaggagggagaggaggaacgagagggactcg
tatctcaatcgaccaggatctagcaacgcagaaaagctttcaggactgagtccaagcttt
gtcttcctgcaactttaccattctcccttctttggcaatgaggccaacaagccactgctg
ttgcccaaaactcaggtgattgaccgtgctgtgaaggtcctggaccagatgccaccgtac
gacacacataaaattggagttgtgtttgtgggagctggacaggtaaacaatgaggtggcc
attctgtcaaatgagtacggttcaaaccgatacacaggatttctaacaggccttggcaaa
ttgatacacctcaaagactgtgaccctgaccagatctttctcggagggcttgaccagtac
ggagatgacggggagttcacctactgctggcacgatgacatcatgcaagctatcttccac
attgccactctgatgccgaacagggagagcgacaaaggctgctgcaacaaaaagcgtcat
attggcaacgattttgtcatggtggtgtacaatgactctggagaggactacaaactgggc
actatcaagggtcagttcaacttcgttgaagttattattaagccactggactacgaatgt
aacctggtaaccctccagtgccgcaaagacctggagaaactggtcgacacgtcggtggca
aaaataatttcagaccgcaaccttccacttttagtcagacagatggctctgcacgcaaat
atggcttcgttggtgcatcagtacagagcaaacccctctgatgcttatgcgtccaagtgg
ctcgcacgattaagacacattaaaaggatcaggaccagggcccaagaggacattcagtct
cgctcgactcccagcatctccctgacccaagtgcacagtcagcagaacaaatcatttcag
cagagcgctccagcaccaaaccctgaaacgtcagggcagaggaagagacttgtgtccaca
gtggatgattttactgattttgtttga

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