Cynoglossus semilaevis (tongue sole): 103387418
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Entry
103387418 CDS
T04866
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
csem
Cynoglossus semilaevis (tongue sole)
Pathway
csem00270
Cysteine and methionine metabolism
csem00480
Glutathione metabolism
csem01100
Metabolic pathways
csem01240
Biosynthesis of cofactors
csem04216
Ferroptosis
Module
csem_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
csem00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
103387418 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
103387418 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
103387418 (gclc)
Enzymes [BR:
csem01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
103387418 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
103387418
NCBI-ProteinID:
XP_008320272
UniProt:
A0A3P8VMY5
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Position
12:complement(10311890..10320761)
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AA seq
630 aa
AA seq
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MGLLSLGSPLNWEESKKYADHIRKHGIIQFLNIYNKLKDRQKDVLKWGDEVEYMLLEMDH
QDQKVRLVLHGEDVVETLQHQGEKINPNHPTLWRPEYASYMIEGTPGQPYGGTMSEFNTV
EANMGKRRREASSVLRQNESICTITSFPRLGCPGFTKPEHRPSPVEKGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIYKDKFTPSPFVEEFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTQEERGLLPLKNNKFRIFKSRYDSIDSYLSSCGDKYNDIDLTIDNEIYEQLL
AAGIDRLLAQHIAHLFIRDPLTVFEEKIHLDDENESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQRRNAV
QEGMFYFRKDIFKGCSTVLDGATSPQNGLESDCGNEEYTLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCAILNYLKLIKKRASGELMTMAKWMREFVAKHPEYKQDSVISDKI
NYDLIQQCDRISKGEEACPELIGTPGNKVK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgctgtcactgggctctccactcaactgggaagagagcaagaagtatgctgac
cacataagaaagcacggcatcatccagttcctcaacatctacaacaagctgaaagatcgc
cagaaagatgtgctcaagtggggcgacgaggttgagtacatgctactggaaatggatcac
caggatcagaaggttcgactcgtcctgcacggtgaagacgttgttgaaactctgcaacac
cagggggaaaagataaaccccaatcaccccacactctggagaccagagtacgccagctac
atgattgaaggaactccaggacagccgtacggcggcaccatgtcggagttcaacactgtg
gaggccaacatggggaagagacggcgagaagcctcatctgtgctaagacagaatgaaagc
atttgcaccatcacctcattccccaggttaggctgtccaggcttcaccaaaccagagcac
cgaccatcccctgttgaaaaaggagtgtccaaatcactgtttttccccgatgaagccatc
aacaggcatccgagatttagcaccctcactagaaacatacgtcaccgaagaggagagaaa
gttgttataaatgtaccaatctacaaagacaagttcactccgtctccgtttgtggaggag
tttcctgaagatgacggtgaagcagccagggcagctctacccgaccatatctacatggat
gccatgggcttcggtatgggcaactgctgtctgcaggtgacattccaggcttgcagtatt
gatgaggcgagatatctttatgatcaactagcaacattttgcccaattgtgatggcgctg
agtgcagcgtcacccttctacagaggctacgtgtcagacatcgattgtcgttggggggtt
atttctgcctcagtggatgacaggactcaggaggagcgtggtttactgcctttaaaaaac
aacaaattccggattttcaagtccagatacgattcgattgacagttatctctccagctgc
ggtgacaagtacaacgacatcgatttgacaatagacaatgagatctacgagcagctgctc
gctgcaggtatcgacagactgctggcccagcacatagcccacctcttcatccgagaccca
ctcactgtttttgaggagaaaatacatctggatgatgaaaatgagtcagatcactttgag
aacatccagtcgaccaattggcagacaatgaggttcaaacctcctccacccaactctgac
atcggctggagagttgagtttcgccccatggaggtgcagctcactgactttgaaaacgct
gcgtacgtggtcttcgttgtgctgctcaccagagtgatcctgtcgtacaaactggatttt
ctaatacctttgtcaaaggttgatgaaaacatgaaggtggcacagagaaggaatgcagtc
caggagggaatgttttacttcagaaaggacatcttcaaaggctgcagcacagtgctcgat
ggcgccacttctcctcaaaatggcctggagagcgattgtggaaatgaagaatatacactg
atgagcattgacacaatcatcaacggaaaggaaggcgtttttcaaggcctcatccccatc
cttaactgctatcttgagaacatggaggtggacgtggacaccagatgtgccattttgaat
tatttgaagctcatcaagaaacgtgcctcaggtgaactgatgaccatggccaagtggatg
cgggaatttgttgctaaacatccagagtacaagcaggacagtgtgatcagtgacaagatc
aactatgacctgattcaacagtgcgacagaatctccaaaggagaagaggcctgccctgag
ctcattggaactccaggaaacaaagtcaaatga
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