Cynoglossus semilaevis (tongue sole): 103387429 Help Entry 103387429         CDS       T04866                                  Symbol dst Name (RefSeq) dystonin   KO K10382   dystonin Organism csem  Cynoglossus semilaevis (tongue sole) Pathway csem04382   Cornified envelope formation Brite KEGG Orthology (KO) [BR:csem00001]  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     103387429 (dst)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:csem04812]     103387429 (dst) Cytoskeleton proteins [BR:csem04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     103387429 (dst) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Plectin SR_plectin_7 CH GAS2 Spectrin_3 Spectrin_2 SH3_10 EF-hand_1 EF-hand_6 EF-hand_7 Spectrin_SYNE1 Spectrin_4 EF-hand_5 CAMSAP_CH Motif Other DBs NCBI-GeneID:  103387429 NCBI-ProteinID:  XP_016892539 LinkDB All DBs Position 12:complement(10508230..10595473) Genome browser AA seq 7638 aa AA seqDB search MMIAAAFLVLLRPYSIQCVLLLLLLLLGTIATILFFCCLHRRLRNGKHPIKSALSGRSRS RVGLRTHHFRSEGFRHSPRHARRSVHARVTEEKQNPIDVPVSEPEASSTLRKRKVKKRVL PEFYQSVQVTPTRKPSTSSGNPSLHCSMSSSADFSDEDDYSLKSGSASPAPGDTLPWNLP RHERSKRKIQGGSILDPAERAVLRIADERDRVQKKTFTKWINQHLLKVRKHINDLYEDLR DGHNLISLLEVLSGDTLPRERGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPK LTLGLIWTIILHFQISEIHVTGESEDMTAKERLLLWSKQITDGYVGVRCDNFTTSWRDGR LFNAIIHKYRPDLVDMSRVSTQTSRSNLEQAFCVAEQLGVARLLDPEDVDVQSPDEKSVI TYVSTLYDAFPKVPDGVDGISPNDVDIKWVEYQNMIKYLSQWIRHNVALMSDRSFPNSPV EIKALYTQYLHFKEHEIPLKENEKTKIKNLYKMLEMWIEFGRIQLPQGHHPNDVEKEWGK LIVAMLEREKSLRPEVERLEMLQQVANRVQRDCLNGEDKLALAQIALQSDAKRLESGIQF LHEAEIAGYLLECENILRQQVVDIQLLLDGKFPFADQLVQRVSRLRDDLLSLRAECSSVY SKGRTLTTEQTKMMISGITQSLNSGFSQSMGTNLTPALTPALTPGGFGTPGSTFTSSLTP CLTPSLTPALTPGLQPSTVQSYMGGGGTVDPGSLRHLKHLQIRKPLQKSSLADPNLTEEE VNMKYVQDLLMWVEEMQMQLDRSEWGSDLSSVEVHLENHKSIHRAIEEFQMSLKEAKLSE IQMTIPLKLSYSDNLKRLEKQYEKLLNSSRERQNHLESLYDFVSHATQELIWLNEKEEEE VAFDWSDRNSNIAKKRDYHADLMKELDEKEETIKLVQDKAERLLFKSHPARITIEAYRAA MQTQWSWILQLCSCVEQHLKENAVYFEFFTDAKESIDYLKGLQDAIQRKYSCDRTSSLHR LEDLIQESMDEKEQLLQYRSTVAGLVGRAKNIVQLKPRNPEMPVRSSLPVKAICDYRQIE ITIYKDDECILANNSHRAKWKVINPAGNEAMVPSVCFTVPPPNREATDMATRMEQLYQNV LALWHHSHINMKSVVSWHNLMADIRAIRKWNVASIKTMLPGEHQQVLSNLQSHFDEFLED TEESEVFTLADCTQLERDVAACKEYYQELLRSAEREEHEESVYNNYISEIRNFRMHLEAH EEHMIRQIRTPLERDDLDQSLQRIAEHERKMAELNKLKEDLDVLKEKCELFLRQAAGSPS APTLSSELTVLVQSMSQVYSMSSIYMDKLKTVSSVVKLSQNSELLVKTYESKLYGEDTIN SDVKSTEAVISTLKQWRTEIDEKQEMFHDLEDALQRARLISERMFKVHNERDFDLDWHKE KADQLNERWQNIHSQTDNRLRDLDSINKSLKHYRETYTSLDEWVREMEVAQLKTQENKPE DSKALAELLNKQKVLVAEIEQKQGSIDECQKYSEQYSSAIKDYELQLMTFRAMVDSQHKS PLKKRKMQSSSDAIQQKFMDLRTRYTALVTLMTQYVKFASETLKRTEDEENRKSFEQAQN AKRTECMDLQKAACNVEISQLKQRLHEQEIMLAERRTQLEKLEAEVGMQQKTIDNLNFQK SNLEHEIHQYRTKLDVVVRDKAATEQELFHTKLLIEQAEAKLSVTQSKLDDLKTQSALLQ RKAIIEAGREEELEHQVQVKVNDLTQQPSAAHSQVVVEGQASAHRENEKKMTEALQEKLK ELVQAQRNADLAEEKAQSFKKLLDDSSNRLKKLQMEVEEEIKSLQRAKSSLEQSTFFQST EIEGLKEQLKITQGELHKKVSTEQENIYKINNFEEEVTCKQAEIDQLKFKCSELTRINVS STNDVRGLQLLTESLEKERSLNEKKIKSLKSEMENWKQKQQAVEEENSSLKRSEQALKLK CKNVEAELENRELVISQLQKKLEELKQINTETDKNLKNMRDNLDQMMAEINTKDQQIQIF KSQALEDELINQKHSTKDLTSSSEKVTQSLKQQLYVLQDEKEASERQIENLNVKLSDLSA SLKKSKDELTREIRERQVRESKILQMECELQKTKLNLNPDKSQSNMQHENTMLKRDKAEV LEKNISLCSEIKTLKEKCEHAEKEAEQKHRENSVLQLKSQQMEEQLEKCKKMLDELKTKL QLQKEGYEKQLVLVQREVEKKLSLLQAEISGEEKSKQQSQSSELAEMLKYFKQDVSPIKT AVNQSNLASTQESAPKQLQVQMDQLQQENSKLSQDLTNAKSKISQLEEDKLKLSLKINAQ RGHGNEELSESDKIKQLLKDSEGKVTTKEHDERTLREQMQAYVKEVKGLQEKILKVGLVP KTDNPKMNKQEVNETSRQQEKDKPLNVNVMAPQKMTSSHEGSTEDKIYKMKILPEMTAVE KGTSLDRVNPLKQDQSQATPGQYLLESRTKKNFSSSTPVRKSSGSSLLETDLTHKSPKTA VEQGTKEKLGHMYPGGPMDPQQKETHSITRTKIYQITQTCEAVNISEKDSAGGDVTTIYS TPQKGSTVKQNLINSKVFEETQYLGKPTAIAGVYVESSKKKISFLEAAEKGFLAKTYALE FLEAQAVTGSLTDLSTGQTLSVVQALERGLIDKGIKDKLKEAEKAVIGYEHAGKKLSVFQ AMEGRLLDRYKGKRFLEVQASTGGLINPDTGVRVPTSLAVDQGLLNKDTLRTLYDPVNNP KGFHNPDTGQKAYYSEILKTCLYDIDGCVLLYPFGDRRLTDSSPSSTHRVSVVNSSAGVE ISAYEAFKGNRIDKRTYLSLSRQESDWQETSTVDASGTTVHIITDVTSGRQLCLESALSQ RFLEPSEFDSYRSGLLTIYEIADLIFSRMVVVEEVNSPVAGLWDVARKKRLSILQGFQQS FIDRTTALRLLEAQACTGGIFDPSSGYKFTVCEAVKRGLVDEALKQQLQQFEQAFKGIDQ PNNAKKLSVFQAVQENVLPKDVGFRCIEFQLLTGGLINPDTHDRVSLEEVIQRGLVDKAT ASILKDETLHNRSLTCPKTKRKITFKEAIDRSVFDCHTGLRLLEARSVDEEKREHTDKVS KLLHWVKQTTNTDGSAVADSNANTDASNKHKASVEEMVTKKEQIAEALRATQTMLSKHSD KMTEEEREEAQEQMKALNQAYSEVSQQCLDQTTSAEEDPNSSLGNAELGSGTNGSLTAQL MSNGQHVTSDASKRNPGYKSTPISEVTDANKCIQSSHVSSVFLSDVAAATKRPTCDDLVI KVIEVTPDSDGVKVCYTGSQLTPEQALQSGHELELDQSSRLMGAILNRNKNLKPGRNVNI LTPVSDGLGDQVQELSVLQEAMGTLNSAPSGDCQDNQLGTLDSIMKESPEAEGERAPEEN LSPQTDACQQEEARNKFPSQLFSIQDYLECVGRLQDHADVLEDLRNDISTPAAVTNNMDE LQVQIEECQSVESQLSELADVLAIDMEKAKLLLSSANEDIPVQIHQDLASAHLELEANVT TVSQLCEEKSHSFIQAMEREKVQLKSKYQKHLTDLDELAGLVQKYSEIQDVDLNACDVDS LNQMIQQSKDTESRLLKEVRHSLEDVTFDIQCFISEHAQFLSAAQSSHLLKFLSSTQRAL RDQTEKIVTHRTTLEHVLETKENESHAKSLLEKHKQLTDKLEDVCGNLTLTENRLIGHQQ QAENTESVTDLQQYQQEHQALQKDVLTNASALNEVISSTKLFLEENRNKLTPDQIATIES KLEEAKSKAKLINERAEESRKDLEKAVTTAIKQESEKAAAVEKLEESKNKIEGLLDWISN IGNENENVLNHNDRISNENGNLPEQTAAKGILEENDDANGNAPQTTENDSGKETGGKSDA SLDLDKQYERVKGHHQQILSQQQDLLLATQSAQALLDKQANVLSPEEKDKLQKNIQELKG RYEASLTQAEQQMKQVQCVQEELKKFQGDCEEFEGWLDQAEGQIEDLGAPAGSLNILSDK LQQQKVFAEDVISHKGDLRFITISGQKVLDVAKACEQSDPAAKNTPMFVDTSGTCSAVKD KLDSAASRYKTLHSQCNQLGNNLKDVVDKYKKYDDSSASLFKWLNSSEEEARKQQSETIA ADPQTLQKQLEETKALQSKMTGQQTAVETLRKTAESLITSEGDLLTNPEEIQETVDDIAE RYDNLSKSVSDRNEKLQITLTRSMSVQDGLDEMMAWMQGVEASVEEKGQIPLDSASIGDI LSREAALEQDIASRQSSISAMKAKVKKFVETADPSAAALLQSKMEALSQRFSDACDKHQR KVSQLEGLREKVEQFESIADKVQQFVVRSTQELNETDSSLKTFDEMSQQMQSTKTEMAEH ADDLAKLQQLCKELCEISPEGNKAQIQSKVENLTNVFSTFKDGVKEKEEEVSSCQEQLKE FRSAASSLNKWLAETNEKVPAVQSSISEKSLEKDLQKVTELLDDWTSKDPAVQDLNSKGS SLCNLITFLTSPAKTKTPNKSALTNGGGPMNHFYLTNKELMEIQQNMSFVNEGYSSLGEM LKSRVAELSSSVQEVNEAQKETEDMMTWLRDMKKTAASWTNAATERDAVKTQLEQQKAFE GNMKQKQEHLQKLREKLLNLIKTHPNSPEASKWKQMLAEIDAAWTDISGSVEQRKERLEQ SNKNLDTFQTAEVQLGQWLSEKELMMSVLGPLSIDPNMLKMQKQQVQILQNEFKSRKPQF EQLEGAGAAILSSPGNQEHSNGKLVREQLDAISQKWRGLTGQLDQRDSLIDQAIVKTGQF QELLKSLSQASVQLENQLTDHQAHSTQPDAVKKQLEDVHNITAQLREEKKKLKEAEVLNA ELTAMVTEDYLKADLTRQLETVSKPFKQLEEKAALRIEQLNSTFASSQQFHQTSKDFQSW LCQRLQDQSKPEVISAKAEVLQQTLEEHSKLQKALSEHEDIYNKITGEGDSLLQNTDGAE KLALQGQLNTMLSNWEEVKRSSAEHGDKLQTALQRSLKFKEHTDQLSSWIQECEVSEGQI KLTTDPVAVESSVSQVKTLQRDVDKHRRMVEQLNMAADSLLEVANVDTQPVKEEKANVGK RVDTLVESLQSKKESLERISHTVKEFNDTYKDARGQLEGAEKYVGAYESQGVQGHSNKNL TNMKAQHKSLEGVQNQVEHLKSLAKDLVVSVPDADGVTDLLLQADSLEKDYSTLNTKLEE TCQELEGKLQGIGQFQVSIREMFTQFTDLDDELDSMAPLDLDLATLKGQQDGIQNFVSKL QELITNTANARDSCQKMLETETSPDLLGLKRDLDALSKQCGKLLDRGKGRETQVKTTLSK LDELYVKLNQVGERLSSAVDKEATQEAVGMETDVIEHQLEAFKAFQKEDIDPLQADLQDI NSVSQSLIQNVTKGTSTKKLEDDLEGINAKWNTLNKKIAERSAQLHEALLRCGRFQDALE SLLSWLTDTEELVASQKPPSAEFKVVKAQIQEQKLLQRLLDDRKPTVELIKREGGKVAEL ADSVDKDKVAKEIECLGQRWDALLKKAENRHKQLESILVVTQQFHDTLEPLSEWLASTEK HLSNSEPVGTETSKLEDQISQHKALEEEIMNHSKDLFQAVSLGQMLRTVSSVDDKDFVQS KLDNMQASYIELQERCRRKAEMLHQALANAQLFGEDEVALMNWLYEVHTRLGEVSVEDHR VEVLEKQLAEQRALQGDIELRKKNVDQAISNGMELLKQTTGDEVVVIQGKLDGIKTKYSE ITSMGDSVLKTLESVLSLSSKLHQTHQDLNSWLEAVEAEISAFADQEPVGDQLVQAQERQ KALLKETKDQKLVADKLNELSGSLLDLIPWHTRESLDKMVSEDNERYRVVCDTVTQQVDR INADILKSQQFEQAADAELSWLSDAEKKLESMGDIRLEQDQNTTQLQTQKIFSMDIMRHK DAVDEIVKMGKAIMNSKSPEEKEVLMTLTQALLDKYNTVSQLNSERCLQLERAHSLASQF WETCEEMWPWLQETLGAFSQLLPPSIEYDKLRQQQEELRQMRELIAEHKPHIDKMNKTGP QLLELSPVEGVPIREKYTVTDQLYTKLKADVKQRADTLDEAISKSTQFHDKIDPMLESLE RIAERLRQPPSVSVEVDKIKDQISENKSVYVDLEKLQPSYETLRQRGDEMIARSEGADKD ISAKVVQDKLDQMVFLWSDIQALLEERESKLLDVMDLAEKFWCDHGALAVTIKDSQDLLR ELEEPGVDPSVVKQQQEFVEGFKEEVDGLQEELEVVQHQGGELMAACGEPDRPVIKKSLD EVVSAWENLNKAWKERGERLEEAMQAAVQFQDGLQGMFDWVDILESKLDSMSAVGTDLET VKQQIVELKEFKGEAYQLQIEMERLNHQAGLMLKKATEESDCCAIQEPMSELKMLWNNLD EKIISRQHKLEGGLLALGQFQHALDELLAWMSHTEELLDEQKKTAGDPKAIEIELAKHNV LQVDVLAHKATVETVNKAGNDLVESSAGEEASGLRTKLENLALRWTAILEKTDQRKQQLE SALLQAQGFHGEIEDMQQWLKDTDRQLLASKAVGGLPDTAREQLNTHLELCSALEVKEEL YKELLNKGRQLLMMLPEGSPDSNTEQDLANMKDKWEAVQGKVAERKVKLEEALKLATDFH NSLQDFINWLTQAEQTINIVSPASLILETIMFQIDEHKVFVTEVNSHREHIIELDKTGTH LKYFSQKQDVVLIKNLLLSVQGRWEKLVQKSVERGRLLDDSRKRAKQFDETWNKLMEWLE ESEKSLDSDMEIANEPDKIKQQLLQHKEFQKALGSKHSVYDTTTRTGRALKDKTSLQDDT QKLDDMLSELRDKWDTVCGKSVERQNKLEEALLFSGQFTDALQALTDWLYRVEPQLAEDQ PVHGDIDLVLSLIDNHKVFQKEMGKRTGSIQALKRSAKELIENSHDDSSWVKVQMQELST RWETVCNLSVSKQARLELALCQAEEFHSSVHILLEWLAEAEQSLRFHGSLPDDEEALRTL IEQHKEFIKKLEEKSMSLNKAISMGEAILGICHPDSITTIKHWNTIIKARFDEVQAWARQ HEQRLAAALTDMLTTQELLENLLNWLRWAESSLDDKDKEVLPQEIEEVKGLIAEHQAFME EMTRKQPDVDKITKTHKRKAAVEPQNQSQIPVLEKGRTGRKRSPTQTMYASATQAHVETK NPRVNLLVTKWQHVWLLALERRRKLNDALDRLEELKEFANFDFDVWRKRYMRWMNHKKSR VMDFFRRIDKDQDGKVTRQEFIEGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAA LHPNKDAYKPLTDADKIEDEVTRQVAKCKCPKRFQVEQIGANKYRFYLGNQFGDSQQLRL VRILRSTVMVRVGGGWMALDEFLVKNDPCRAKGRTNLELREKFILPEGTTQVMASFRYRG RRSRPSSRGASPNRSTSSQSCPVPVNPVTTSTPKTPQHITRNYDKPWLTNSKSSTPLKSS DSFQSQTSSSEVTPVQGSKLRLPGYLSGKGFQSGEEGTLISAAVLKARAQAAGESRRNSS RPGSKAGSRGSSRRGSDASDFDISDIQSVCSDMSETVGESTRATPRPASHQRGGKPSKIP TPQRKTPPTSKLAKGSKR NT seq 22917 nt NT seq  +upstreamnt  +downstreamnt atgatgatcgctgcggcgtttttggtcctgctcaggccgtacagcattcaatgtgtgctg cttctgctgctgcttctgctcgggaccattgcgacaatcttatttttctgctgcttgcat cgcaggctgcgtaatggaaagcacccaataaaatctgcgctctccggacgctccaggagc cgggttggcctgaggacgcaccattttcgttcagagggcttcaggcacagtccacgtcat gcaaggaggagcgtacatgctcgggtgacagaggaaaaacaaaatcctattgatgttcct gtgagcgaaccagaagcatcatccactctaagaaaacgcaaagtgaagaagagagtgctg ccagaattttaccagtctgtacaagtcacccccacacgcaaacctagcaccagctcgggg aacccttccctgcactgctccatgtcttcctcggctgatttctcagacgaggatgattac agccttaaatccggctcggcatcaccggctcccggggacactttgccctggaacctgccc agacatgagcgatccaagaggaaaatccagggaggatccatcctggatcccgcggagaga gcagtgttgaggatcgcagatgaaagagacagagtgcagaagaagacatttacaaaatgg ataaatcagcatctactgaaggtacggaagcacataaatgacttgtacgaagacctgcga gatgggcataacctgatctcactgctggaggttttgtctggagacacattgccacgggaa agagggaggatgcgtttccacagactccagaatgtacaaatagcactggattatttaaaa aggcggcaggtcaaacttgtaaatatcaggaatgatgacatcacagatgggaatcccaaa ctgaccctgggactgatctggactataattttgcactttcaaatctcggagatccatgtg acaggggagtccgaggacatgacagccaaggaaaggctgctgctctggtccaagcagatt acggacggatacgtcggcgtacggtgcgacaacttcacaacatcgtggagggatgggagg ctgtttaacgccattattcacaaatacaggcctgacctggttgacatgagtcgtgtctcc actcagaccagccggtcaaatttagagcaggcattttgtgtagctgaacaactgggggtg gccagactgctcgaccctgaggacgttgatgttcagtctcccgatgaaaaatccgtcatc acatacgtctccacactttacgatgccttccctaaagtaccggacggtgttgatggaatc agtcctaatgatgtggatatcaaatgggtggagtaccagaacatgatcaaatacctcagc cagtggatcagacacaatgtggccctaatgtcagacagatcattccccaacagccctgtg gaaattaaggcactttatacgcagtatttacactttaaagaacatgaaatcccactgaaa gaaaatgagaagacgaagataaaaaacctctacaaaatgctcgagatgtggatcgagttt gggcggatccagttacctcagggtcaccaccccaacgatgtggagaaggaatggggtaaa ctgattgttgcaatgctggaacgggagaagagcctgaggcctgaggtggagaggctcgag atgctgcagcaggttgccaacagggttcagcgagactgtttgaatggagaagacaagctg gcactggcacagatcgccctgcagtctgatgcaaaacgactggagtctgggattcagttc ctgcatgaagcagaaatcgctggctacttgttggaatgcgagaacatcctgaggcagcag gtggtggacatccaacttctcctggacggaaaattcccttttgcagatcagcttgttcaa agggtgtcaaggctgcgagacgaccttctaagcctgagggctgaatgttcttctgtgtac agcaaaggacgaactctgacaacagaacagaccaaaatgatgatctcaggcatcacacaa agtctgaattctggcttctcccaaagcatgggcacaaacctgacaccagctctcactcct gcactcacccccggagggttcggcactcccggttctaccttcacctctagccttactcca tgtttgaccccatccttgactcccgcgttaacccctggcttgcagccttcgacggtgcag agctacatgggcggtggtggcactgtggatcctggaagcctcaggcatttgaaacacttg cagatccgtaaacctctgcagaaatcctcactggccgaccccaatctgacagaggaggag gtcaacatgaagtacgttcaggatcttctgatgtgggtggaggagatgcaaatgcagctg gatcgctctgagtggggatcggatttgtccagtgtggaggtgcatttagaaaatcacaaa agcatccacagagctatcgaagaatttcagatgagccttaaagaagccaaactgagtgaa atccagatgaccattccactgaaactctcgtattcagacaacctgaaaagactggaaaag cagtatgaaaagctattgaactcttcaagggagcgacagaatcacctggagagcttgtac gactttgtgtcacacgccacgcaggagctcatctggttgaatgagaaggaggaggaggag gtggccttcgactggagcgatcgcaacagcaacatcgccaagaaaagagactaccatgct gacctgatgaaggagcttgatgaaaaggaggaaaccatcaaactggtgcaggacaaagca gaacgcctcctgttcaagagtcatccagccaggataaccatcgaagcctacagagctgcc atgcagacacagtggagctggattttgcagctctgctcgtgtgttgaacagcatctcaag gagaacgcggtttattttgaatttttcactgacgccaaagagtccattgactacctgaag ggcctgcaggatgccattcaaaggaagtacagctgtgatcgaacaagcagcctacacagg ctggaggacctcattcaagagtcaatggatgagaaagagcagctccttcagtaccgcagc actgtggctgggttagttggcagagctaaaaatattgtgcagctcaaacccaggaaccct gaaatgcccgtgaggtcgtccctccccgtaaaagccatctgtgactaccgtcaaatcgag atcaccatttacaaagatgatgagtgcattttggccaataactcccaccgcgccaagtgg aaagtcatcaatcctgcagggaacgaggccatggtgccttcggtttgtttcactgtgcct ccacccaacagagaggccactgacatggcaaccagaatggagcaactgtatcagaatgtt ctggccctgtggcaccactcccacatcaacatgaagagtgtggtctcctggcataatcta atggctgatatacgagccatccgtaaatggaatgtagcctcgataaagaccatgttacct ggtgagcaccagcaggtcctaagcaacctgcagtcccattttgacgagttcctggaagac accgaggagtctgaggtattcactctggcagactgcacccagctggagagagacgtggca gcctgcaaagagtactaccaggaactgctcagatctgcagagagagaggagcacgaagag tcggtctacaataattacatctcggaaatacgcaacttccgcatgcatctggaggcccac gaagaacacatgatcaggcaaatccgcacgccgctggagagagacgaccttgaccagagt cttcagcgtattgcggagcacgagagaaagatggcagagctgaataagctgaaggaggat ctggacgtcctgaaggagaagtgtgaactcttcctcagacaggctgcagggtctccgtca gctcccactctgtcctctgagctgacagtcctcgttcagagcatgagccaagtctactcc atgtcttccatttacatggacaaactgaaaacagtgagctcagtggtgaagctaagccaa aactcagagttgctagtcaaaacctacgaatccaaactctacggcgaagacaccatcaac tcagacgtcaaatccaccgaggctgtcatttcaacgcttaagcaatggcgaacagagatc gatgagaaacaggagatgttccatgatttggaggatgctctgcagagggctcgacttatc agcgagcgcatgtttaaggtgcacaacgagcgtgacttcgacctggactggcacaaggaa aaagctgaccagctgaacgaacgatggcagaacattcactctcagactgacaacagactt cgggacctggacagcatcaataaatctctgaaacactacagagagacttacaccagtctg gatgagtgggtgagagaaatggaagtagcacagctaaaaacacaagaaaacaaaccagag gacagcaaggcactggctgagcttcttaacaaacagaaggtccttgtggctgaaattgaa caaaaacaaggttcaatagatgaatgtcaaaaatactcagagcaatattcatctgccatc aaggattatgaacttcagctgatgaccttcagagctatggtcgactcccaacacaagtct cccctcaagaaacggaagatgcagagctcttctgatgccattcagcagaagttcatggat ctcaggacacgatacactgctctcgtcactctgatgacacagtatgtgaagtttgccagt gaaacactgaagagaactgaagacgaggagaacaggaaatcctttgaacaggcacagaat gcaaaaaggacggagtgcatggacctccaaaaagctgcgtgtaatgtagagattagtcaa cttaagcaacggctccacgaacaggagattatgttggctgaaagacggacacagctggag aagctggaggcagaagtagggatgcagcagaagactattgacaatcttaactttcagaaa tcaaacctcgagcatgaaattcatcagtatcgcaccaaattagatgtagtggtaagggac aaggctgccactgagcaggagttatttcacaccaagctgttaattgaacaggcagaggcc aaactgtcagtgactcagagtaaactggacgatcttaaaacacagagcgctcttcttcag aggaaggcaatcattgaggcaggacgtgaggaagaattagaacatcaagtccaggttaaa gtcaatgatctgactcagcagccttctgcagctcacagtcaggtggtggttgaagggcag gcatctgctcatagagaaaatgaaaagaaaatgacagaggctttgcaggagaaattaaag gaactagtccaggcccagagaaacgcagacctggccgaggagaaggcacagagttttaaa aagctgctggacgacagcagtaacaggctgaagaaacttcagatggaggtggaagaggaa atcaagtcgctccagagagcaaagtcctccctggaacaaagcactttcttccaaagcaca gaaatcgagggcctcaaggagcagctgaagataacacaaggggaactccacaagaaggtt tccacagagcaggagaacatctacaagattaacaactttgaagaggaagtaacatgtaaa caggcagaaatagatcagttgaagtttaaatgcagcgagctgacgagaattaatgtttcg tctaccaatgatgttcgagggcttcaacttctgaccgagtccctggagaaagagaggtcg ttaaatgagaaaaagatcaagtctttaaagagtgaaatggaaaactggaagcagaaacaa caggcggtcgaggaggaaaacagttcactgaaaagatctgagcaggccttaaaactcaaa tgtaaaaatgttgaagctgagcttgagaacagggagttagttatatcacagctgcagaag aaattggaagagttaaaacagataaacactgaaacagacaagaatttgaagaacatgaga gataacctggatcagatgatggctgaaattaacacgaaagaccagcaaattcaaatcttt aagtctcaggctttagaagatgagcttatcaatcagaaacacagcacaaaagacttgacc agcagttcagagaaagtgacacagagtctcaaacagcagttgtatgtccttcaagatgag aaggaagcatcagagaggcagatagagaacctcaatgtcaaactttcagatttgagtgcc tccctgaaaaaatctaaagatgaactgaccagagagatcagagagagacaagtgagagag tcaaaaatcctgcagatggagtgtgagctccaaaaaacgaaacttaatctgaatcctgac aaatcccaatcaaacatgcaacatgagaatacgatgctaaagagggacaaagctgaggtt ctggaaaagaacatatcgctgtgttctgaaatcaaaacgctcaaagaaaaatgcgaacat gctgaaaaagaagccgagcaaaagcacagagaaaactcggtgcttcagctgaaatcccag 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tcacggcaggaaagcgactggcaggaaacgtccacagttgatgccagtggtaccacagtt catattataactgatgtcacaagtggtagacaactttgtttggagtctgctcttagtcag aggtttcttgaaccttcagagtttgacagctatcgcagtggccttctcaccatctatgag atcgcagaccttatattttcaagaatggttgttgtcgaggaagtcaacagccctgttgct ggtctctgggatgtagctcgtaaaaagaggctgtcgatccttcaggggttccagcaaagt tttattgatagaaccactgccttgagattactggaggctcaggcctgcactggaggtata tttgacccctcatcaggctacaagttcacagtctgtgaggcagtaaaacgaggtctggta gatgaagcattaaaacagcagcttcagcagtttgagcaggcttttaaaggcatcgatcaa ccaaacaacgcgaagaaattgtcagttttccaggcagtgcaggaaaatgtcctccccaag gacgtgggatttcgctgcattgaattccagctcctgaccggaggtttgataaatcccgac actcatgacagagtctcactggaagaggtcattcagagaggtcttgtggacaaagcaacc gcctccattctgaaagatgaaacgctccacaacagaagcctcacctgtcccaagaccaag agaaaaatcacattcaaagaagccattgacagaagcgtctttgactgtcacactggcctg cggttactggaggctagatctgttgatgaggagaagagagagcacactgataaagttagt aaactattgcactgggtgaaacagaccacaaacactgatggctctgctgtggcagacagc aatgccaacactgatgcttctaataaacacaaggcatcagtggaggaaatggtcacgaag 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aacggaaagctggtgagagagcagctcgatgctatcagtcaaaagtggcgaggccttact gggcagctggaccagagagacagcctcatagaccaggccatagtgaagacgggtcagttc caggagttactgaagagtctcagtcaggcatctgttcaactggagaaccagctgaccgac catcaggcccacagcacacagcctgatgctgtgaagaagcagttggaggacgtccataac atcacagctcagctgagagaggagaagaagaagctgaaggaagccgaggttctcaacgca gagctgacagcgatggtgacggaggactatctgaaagcagacttgacgaggcagctggag acggtcagcaaacctttcaaacagctggaagagaaagcagcactaaggattgagcagctg aattcaacctttgcaagttctcaacagtttcatcagacctccaaagacttccagtcttgg ctctgtcagcggctccaggaccagtctaagcccgaggtcatctctgccaaagcagaagtc ctgcaacaaaccttggaggaacacagtaaactccagaaggctctcagtgaacacgaagac atttacaacaaaatcactggggaaggggattcgcttcttcagaacactgatggtgcagag aagttggcacttcaagggcagctcaataccatgctttccaactgggaggaggtaaaaagg agctcggcagagcacggagataaactccagactgctcttcagaggtctctgaagttcaag gagcacactgaccagctcagctcctggattcaggagtgtgaagtcagtgaaggccaaatc aaactaaccactgatccggtggctgttgagagctctgtgtcccaggtcaaaactcttcag agggatgttgacaagcacaggaggatggtggagcagctgaacatggctgcagacagcctt 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aactctgtcagtcagagtctgatccaaaatgttaccaaaggcaccagcaccaagaagctt gaagacgacctggagggcatcaacgcaaagtggaataccttgaacaaaaagattgctgaa cgctcggcccagctgcatgaggccctgttgcgttgtggtagatttcaggatgctctggag tctctgctcagctggttgacagacacagaagaactggtggccagtcagaaacctccctct gctgagttcaaagtagtgaaggcccagatacaggagcagaagctcttacagaggctgctg gacgaccgaaaacccacagtggagctaataaagagagagggaggaaaggtcgcagagctg gcagactctgtggataaagacaaggttgccaaagagattgaatgcctagggcagaggtgg gacgctctgcttaagaaagctgagaacaggcacaaacaactagagagcatcctggtggtc actcagcagttccacgacaccctggagcctctgagtgagtggctggcctccacggaaaaa cacctgtccaactctgaaccagtcggtacagagacgtccaagctggaggaccagatctct cagcacaaggccttagaggaggagattatgaatcacagtaaagacctgtttcaggcagtc agtctgggtcagatgctcaggactgtgagctcagtggatgataaggactttgtccagtcc aaactggacaacatgcaggccagttacatagagctgcaggagcgatgcaggaggaaagcc gagatgttacatcaggctctggcaaacgcgcagctgtttggagaagatgaggtggcgctc atgaactggctgtacgaggtgcacaccaggctgggtgaagtgtccgtggaggaccacaga gtagaggttcttgaaaagcagctggcagaacaacgggcactacaaggtgatattgaatta 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atgagagagctgatcgccgagcacaagcctcacattgacaagatgaataagacggggcct cagttacttgaactgagcccagtggagggagttcccatcagagagaagtacacggtaact gaccaactttacaccaaactgaaggccgacgtcaagcagagggcagacactctggatgag gccatctctaagtccacccagtttcatgataaaatcgacccgatgcttgaatctctggaa cggatcgccgagcgcctgcgtcagcctccgtccgtctcagtggaggttgacaagatcaag gatcagatcagtgaaaacaagtcagtctatgtggacttggagaaactgcagccttcgtat gaaacactgcggcagcgcggtgacgagatgatcgctcggtctgaaggagcggacaaggac atctctgctaaagtcgtacaagacaaactggaccagatggtgttcctgtggagcgacatc caggccctgctggaggagcgcgagtccaagctgctggacgtgatggatttggcagagaag ttctggtgcgaccacggtgctctggcggtcaccattaaagacagccaggacctgctgagg gagctggaggagcctggagtggatccttcagtggtcaaacagcagcaggagtttgtggag ggatttaaggaggaggtggacgggctgcaggaagaactcgaagtggttcaacaccaaggt ggagaactgatggctgcctgtggagaacctgatagacctgtgataaagaaaagtcttgac gaggtggtttcagcctgggagaatctaaacaaagcttggaaagagagaggagagaggctg gaagaagccatgcaggctgctgtgcagtttcaggacggcctccaggggatgtttgactgg gtggatatcctggagagcaaactggattcaatgtccgctgtaggcacagacctcgaaact gtgaagcagcagattgtggagctcaaggagttcaaaggggaggcgtaccagctccaaatc gagatggagcgcctgaaccaccaggcaggcctcatgctgaagaaagccacagaggagagc gattgctgtgccattcaggaacccatgtctgaactgaagatgctgtggaacaacctggat gagaagatcatcagtcgacagcacaaactggaaggaggccttcttgctttgggacagttc cagcatgcactggacgaactgctggcctggatgagccacactgaggagctgctggatgag cagaagaagacggcaggagaccctaaagctattgagatcgagctggcaaaacacaacgtt cttcaggtcgatgttttggctcacaaagccacggtagagacggtgaacaaagctgggaat gatctggtggagtccagtgccggtgaggaagcatcaggcctgagaaccaaactggagaac ctggccctgcggtggacagcaatcttggaaaagacagatcagaggaagcagcagctcgag agcgctctgctccaggcccagggtttccatggtgagatagaagatatgcagcaatggctg aaagacacagatcgtcagctgttggcatcaaaggctgtgggaggtttaccagacacggcc cgagagcagcttaacacccatctggagttgtgttccgccctggaggtgaaggaagaactc tacaaggagctgctgaacaaaggtcgccagctgctcatgatgctgccggagggttctcct gacagcaacaccgagcaagatctcgccaacatgaaggacaaatgggaggcggtgcagggg aaggtcgctgagagaaaggtgaaactggaggaagccttgaagctggccacggacttccac aactctctgcaggacttcatcaactggctgacccaagcagagcagaccatcaacatcgtt tctcctgcttcgctcattctggagaccatcatgtttcagattgatgagcataaggttttt gtgacagaggtcaactcccacagagaacacatcattgaactggacaagaccggcactcat ttgaagtacttcagccagaaacaggatgtggtcctgattaaaaacctgctgctcagcgtg cagggccgctgggaaaagctggtgcagaagtctgtggagcgaggccgtctgctggacgac agcaggaagagggccaaacagtttgatgaaacgtggaataaactgatggagtggttggag gaatccgagaagagtctggattcagacatggaaatcgctaatgagcctgacaaaatcaaa cagcagcttttacagcacaaggagttccaaaaagctctgggaagcaaacactcagtgtac gataccaccacgcgaacaggacgcgccctgaaagacaagacatcgctccaggacgatact cagaaactggacgatatgctgagcgagctgagagacaaatgggacactgtctgtgggaag tcagtggaaagacaaaacaaactggaggaggcgctgctgttctcgggacagtttactgac gctctccaagctctcaccgactggctgtacagagtggaaccacagctggccgaggaccag cccgtccatggagacatagacctagtcctcagcctgattgacaaccacaaggtattccag aaggagatgggaaagaggacagggagcattcaggccctaaaacgttctgcaaaggagctg atcgagaacagccatgatgactcgtcctgggtcaaagttcagatgcaggagctgagcacc cgctgggagacagtgtgcaacctgtcagtgtccaaacaggcccggctggagctggccctg tgtcaggctgaggagtttcactcaagtgttcacatcctgctagaatggttggcggaggcg gagcagagtttacgtttccatggcagcctgcctgatgatgaagaggctctgaggacgctg atcgaacagcacaaggagttcatcaagaaactggaggagaaaagcatgtctttaaacaaa gccatcagtatgggtgaagccattctaggcatctgccacccagactccatcaccaccatc aagcactggaacaccatcattaaagctcggtttgacgaggtacaggcctgggcccggcag catgagcagcgattggctgcggccctcactgacatgttgaccactcaggagctactggag aatctgctgaactggctgcgctgggctgagagcagtctggacgataaggacaaggaagtg ctgccacaagagattgaagaggtcaaaggtctcatagcagaacatcaggcgttcatggag gaaatgaccaggaagcaaccagatgttgacaagatcaccaagacacacaaacggaaggct gccgtggagcctcagaaccagtcacagatcccggtgcttgaaaaaggaagaactggaaga aagcgttcgcccacacaaaccatgtacgcttctgcaacacaagctcacgttgaaaccaag aaccccagagtcaacctgctggtcaccaagtggcagcatgtgtggctgctggctctggag cggaggaggaaactcaacgatgctctggacagactggaggagctgaaagaattcgccaac tttgactttgacgtgtggcggaagcgttacatgcgctggatgaaccacaagaagtcccgt gtcatggacttcttccgtcgcatcgataaagatcaggatggcaaagtgacccgacaggag ttcatagaaggcattctctcctccaaattccccactagtcgtttggagatgagcgccgtc gcagacatcttcgacagagacggcgacggctacatcgactactatgagtttgtagcagct cttcatcccaacaaagacgcctacaaaccactgacagacgcagacaaaatcgaagatgag gttacacgtcaagtagcaaaatgcaaatgtccgaagagattccaagtggagcaaatcggt gccaacaaataccggttctaccttggaaatcagtttggagactctcagcagctccgcctg gtgcgtattttacgcagcactgtgatggtgcgagtgggaggaggctggatggctctggat gagttcctggtgaagaacgacccctgtagagctaaaggcaggaccaatctggagctgcgg gagaagttcatcctccctgaaggcaccacacaggtcatggccagcttccgctaccgaggc cggagatctcgaccctcgtccagaggagcttcaccgaacagatccacctccagtcagagc tgtcctgtcccagtgaacccagtcacgaccagtacacctaagactccccaacacataacc cgcaattatgataaaccctggcttacaaacagcaaatcctccactccacttaaatcatca gactcctttcagagccaaacatcatcatcagaggtgacaccagttcaaggtagcaaacta cgtcttccaggatatttgtcaggtaaaggatttcagtcaggggaggagggaacgctgatc agtgctgcggtgctgaaggctcgggcacaggcagcaggtgagtcaagaagaaattcaagc cgacctggaagcaaagcaggaagcagaggaagcagccgcagaggtagcgacgcctccgac tttgacatctcagacatccagtccgtctgctctgacatgtctgagacagttggtgagagc accagggctacacctcgccctgcgtcccaccaacgtggaggtaaaccctccaagatcccc actcctcaaagaaaaacccctcccacgagcaagctggccaagggatccaagcgatag

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