KEGG   Cynoglossus semilaevis (tongue sole): 103396566
Entry
103396566         CDS       T04866                                 
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
csem  Cynoglossus semilaevis (tongue sole)
Pathway
csem00562  Inositol phosphate metabolism
csem01100  Metabolic pathways
csem04012  ErbB signaling pathway
csem04068  FoxO signaling pathway
csem04070  Phosphatidylinositol signaling system
csem04081  Hormone signaling
csem04140  Autophagy - animal
csem04150  mTOR signaling pathway
csem04210  Apoptosis
csem04218  Cellular senescence
csem04370  VEGF signaling pathway
csem04510  Focal adhesion
csem04620  Toll-like receptor signaling pathway
csem04625  C-type lectin receptor signaling pathway
csem04810  Regulation of actin cytoskeleton
csem04910  Insulin signaling pathway
csem04914  Progesterone-mediated oocyte maturation
csem05100  Bacterial invasion of epithelial cells
csem05132  Salmonella infection
csem05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:csem00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    103396566 (pik3ca)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103396566 (pik3ca)
   04370 VEGF signaling pathway
    103396566 (pik3ca)
   04068 FoxO signaling pathway
    103396566 (pik3ca)
   04070 Phosphatidylinositol signaling system
    103396566 (pik3ca)
   04150 mTOR signaling pathway
    103396566 (pik3ca)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    103396566 (pik3ca)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103396566 (pik3ca)
  09143 Cell growth and death
   04210 Apoptosis
    103396566 (pik3ca)
   04218 Cellular senescence
    103396566 (pik3ca)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103396566 (pik3ca)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103396566 (pik3ca)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103396566 (pik3ca)
   04625 C-type lectin receptor signaling pathway
    103396566 (pik3ca)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103396566 (pik3ca)
   04914 Progesterone-mediated oocyte maturation
    103396566 (pik3ca)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    103396566 (pik3ca)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103396566 (pik3ca)
   05100 Bacterial invasion of epithelial cells
    103396566 (pik3ca)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:csem04131]
    103396566 (pik3ca)
Enzymes [BR:csem01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     103396566 (pik3ca)
Membrane trafficking [BR:csem04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    103396566 (pik3ca)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 PI3K_p85B DUF2321 ABC1 C2 Ribosomal_S15
Other DBs
NCBI-GeneID: 103396566
NCBI-ProteinID: XP_008332924
UniProt: A0A3P8X0H3
LinkDB
Position
2:8129409..8153083
AA seq 1068 aa
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDACGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
VFLMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDTVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNFNLSGQSNRVARDHALTEGDTEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMIIPEILPKILLAVKWNSRDEVAQMYCLLKDWPSIRPEQAME
LLDCNYPDPMVRQFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctcccaggccgtcctcaggggagttatggggcatccacttgatgccacctaggatc
ctggtggattgtttgctgcccaatggcatgattctgaccctggagtgtctccgtgaggca
acgctcattacaatcaaacatgagctcttcaaggaagcaaggaaatatcctctccatcac
ctcctacaagaggagacatcctacatttttgtcagtgttacacaggaagcagagcgggag
gagttctatgatgagacacggaggttgtgtgatctccgacttttccagcccttcctcaag
gtcattgaacctgttggaaacagagaagaaaagatactcaacagagagattggtttcgcc
attgggatgcctgtgtgtgagtttgaccttgttaaggaccctgaagtgcaggacttcagg
agaaacattctaaatgtgtgtaaagactccgtggagttgagagatgcatgtgggccacac
agcagagcactgtatgtttacccacccaacgtggaatccacgcaggaacttcccaaacac
atctatagcaaactggacaaaggtcagatcattgtggtgatatgggtgattgtttctccg
aacaatgacaaacagaagtacacactaaagattaatcatgactgtgtgcctgagcaggtg
attgcggaggctattcgtaagaagacgcgcagcatgctgttgtccccagagcagctgaag
atgtgtgttcaggaataccagggtaaatacatcctaaaagtctgtggctgtgatgagtac
ctgctggaaaagtaccccatcagtcagtacaagtatattcgtagttgcatcatgctgagc
aggatgcctaacctgatgctgatggccaaggacagcctttacactcagttgcccacggat
gtatttttaatgccgtcatactcccggcgcatctctacagctacgtcctacatgaatgga
gaggcagctgccaagtcattgtggaccatcaatggaactctgagaataagaatcctctgt
gccacttacgttaacgtcaacatacgggatatagacaagatctatgtgaggaccggcatt
taccatggaggtgaacagatgtgtgatactgtcaacacacagagagtgccctgctctaat
cctaggtggaatgagtggctcacatatgacatgtacatccctgacatcccacgtgctgcc
agactctgcctgtctatttgctcagtcaagggcagaaagggtgccaaagaggaacattgt
ccattagcctggggtaatgtcaacttgtttgactacactcacactttagtggccaacaag
atggcactgaatctttggcctgtccctcatggccttgaagaccttcttaatcctataggg
gtcacggggtccaaccccaacaaggaaacgccatgtttggagctggagtttgaccacttc
agcagtccagtcaaatacccagacatgaatgcagtagaggatcatgctaactggaccatc
tccagagaactgggattcaacttcaacttgtctggtcagagcaatcgtgttgcccgagat
catgcactaacagagggcgacacggagcagctgaagcagctgagcaacagagaccctctg
tcagaaatcactgagcaggagaaagatttcctctggagacacagacactactgcatgatc
atccctgagatccttccaaagatcctcctcgctgtaaagtggaactccagagatgaggtc
gcacagatgtactgcttgttgaaggactggccgtccattcggcctgaacaggccatggag
ctgttagactgtaactacccagaccccatggtcagacaatttgctgtgcgctgtcttgac
aaatacctaactgatgacaaactgtctcagtacttgatccagctcgtacaggttttaaaa
tatgagcagtatcttgacaatcctctggctcgctttctactcaaaaaggccctgaccaat
caaaggataggacatttcttcttctggcatctcaagtcagaaatgcacaataaaacagtg
agccagcgatttggacttctgttagaggcttactgcagggcatgtggcatgtacctgaaa
cacctgagcagacaggtggaggctatggaaaagctcataaacctgactgatatcctgaaa
caggagaagaaagatgagacgcaaaaggtccagatgcggtttctcgtggaccagatgaag
agacctgactacatggatgccctgcagaacttcacctctccactcaaccctgcacaccaa
cttggaaacctgaggttagacgaatgcaggatcatgtcgtcagcaaagagaccattgtgg
ctgaactgggaaaatcctgacatcatgtctgaacttcttttccagaacaatgaaatcata
tttaaaaatggagatgacttgcggcaggatatgctgacgttgcagattatcaaaatcatg
gagaatatttggcagaatcagggactggacctgcggatgcttccctatggctgcctgtca
ttaggagactgcgtgggcctcattgaggtggttcgcagctcccacacgatcatgcagatt
cagtgtaaaggaggtttgaaaggagctctgcagttcaactcgaacactctgcatcagtgg
ctcaaggacaagaacaagggcgagatgtatgacatggctgtggatttatttacaaggtcc
tgtgctggctactgtgtagctacatttatcctggggataggagacagacacaacagtaac
ataatggtcaaagatgacggtcagttgtttcacatagattttggacattttcttgatcac
aagaagaagaaatttggctacaagagagaacgagtgccctttgttctgacacaagacttc
cttattgtcatcagcaaaggatcccaggagtgcgcaaagaccaaagagtttgagaggttc
caggagatgtgttacaaagcctacctggccatcaggcagcatgcaaacctcttcatcaac
ctcttctccatgatgctgggctctggcatgcctgagctgcagtcatttgacgacattgcc
tacatccggaagactctggccttggagaaaagtgagcaggaggccttggactactttatg
aaacagatgaacgatgctcaccatggaggatggaccacaaagatggactggattttccac
acaattagacagcatgcactaaactga

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