Thermoclostridium stercorarium subsp. stercorarium DSM 8532: Cst_c10780
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Entry
Cst_c10780 CDS
T02440
Symbol
leuA1
Name
(GenBank) 2-isopropylmalate synthase LeuA
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
css
Thermoclostridium stercorarium subsp. stercorarium DSM 8532
Pathway
css00290
Valine, leucine and isoleucine biosynthesis
css00620
Pyruvate metabolism
css01100
Metabolic pathways
css01110
Biosynthesis of secondary metabolites
css01210
2-Oxocarboxylic acid metabolism
css01230
Biosynthesis of amino acids
Module
css_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
css00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Cst_c10780 (leuA1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Cst_c10780 (leuA1)
Enzymes [BR:
css01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Cst_c10780 (leuA1)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Mistic
Motif
Other DBs
NCBI-ProteinID:
AGC68076
UniProt:
L7VNN4
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All DBs
Position
1170157..1171824
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AA seq
555 aa
AA seq
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MNWRKYRKFPAFVFKERTWPDRTIEKAPIWCSVDLRDGNQALPDPMNVEKKLKMFNLLKK
IGFKEIEVAFPSASNTEFRFVRKLIEEGYLDDDTVIQVLTQSREHLIRKTFESLKGAKQA
IVHLYNSTSEQQRRIVFKKDKPDIIKIAVDGTKLVKQLSQECDTDIRFEYSPESFTGTEM
DFALEICERVLEVWQPTPEKKAIINLPATVELTTPNVYADQIEWFCNKISCRDSVIISVH
THNDRGTGVAATELALLAGADRVEGTLFGNGERTGNLDIITVALNMFSQGIDPGLDISDI
NSIIKVYEECTNLKVHERHPYAGKLVFTAFSGSHQDAINKGFRYLREEKPEYWDVPYLPI
DPTDIGRQYEAIIRINSQSGKGGVAFIMEHEFGYILPKEMHPEFGEMIKQKSDEAGRELS
PDEVMEVFSENYLNVTGPYKLIGYHVETRDGTVIVNARIYKDNEFLEISGKGNGPISAFF
DALKNISGDLPFRFEAYSEHALSSGADAEAVAYIQLANGGGKSIFGVGKDRNTTTASFEA
IICALNRAAAENKHV
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
atgaactggagaaaatacagaaaatttccggcctttgtctttaaggaaagaacatggcct
gacaggaccattgaaaaagccccgatatggtgcagtgttgatcttagggacggaaaccag
gccttgcccgacccgatgaatgttgaaaagaaacttaagatgttcaatcttcttaaaaag
atagggtttaaggaaatagaagttgcttttccttctgcttcgaatactgaattccgcttt
gtacggaagcttattgaagaagggtatctggatgatgataccgtaatccaggttttgacc
caatcaagggaacatctgatcagaaaaacctttgaatcccttaaaggagcgaaacaggcc
atagtacacctgtataattcaacttcggaacagcagcgccgcatcgttttcaaaaaagac
aaacccgatatcataaagattgccgttgacgggacaaagctggttaaacagctgagccaa
gaatgcgatacagatatcagatttgaatattctcctgaaagctttaccggtacagaaatg
gactttgcgcttgaaatatgcgaacgggtattggaagtatggcagcccactcccgaaaag
aaagccataatcaatcttcctgccacggttgagctgacaacaccgaatgtttatgccgat
cagattgaatggttttgcaacaaaataagttgcagggacagtgttataataagcgttcat
acgcacaatgaccgcggaaccggagttgctgcaaccgaactggccttgcttgccggagcc
gacagggtggaaggcacgcttttcggtaacggggaaaggacaggaaaccttgacatcata
accgttgcgttaaatatgttctcccaaggcatagatcccggcctcgacatatctgacata
aattcaataataaaggtttatgaggaatgcaccaatcttaaggtgcatgaaagacaccca
tatgccggtaaactggtgtttaccgcattttcagggtcgcaccaggacgcaatcaacaaa
ggtttcaggtatttgagggaagaaaagcccgaatactgggatgttccgtatctcccaata
gaccctacagacataggaaggcagtatgaagccattatcaggattaacagccagtcaggc
aaaggcggtgtggcattcattatggaacacgaattcggatacatactgcctaaggaaatg
catcctgaattcggggaaatgatcaagcagaaatccgacgaggccggaagagaactgtcg
cctgacgaagttatggaagtgttcagcgaaaactatttgaatgtcacaggaccgtataaa
ctgataggctaccacgttgaaacaagggacggtaccgtaatcgtaaatgcaagaatatac
aaggataatgagtttttggaaatatcagggaaagggaacggaccaatttcggctttcttt
gatgcgctgaaaaatatcagcggagatctcccgttccggtttgaagcctattcagagcat
gctctttcaagcggtgcggatgccgaagccgtagcatatatacaattggcaaacggcgga
ggaaagagtatttttggcgtgggaaaggacaggaacaccactactgcctcctttgaggcg
ataatttgcgcgctgaacagggctgcggcagagaataaacatgtataa
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