Acetoanaerobium sticklandii: CLOST_0414
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Entry
CLOST_0414 CDS
T01334
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cst
Acetoanaerobium sticklandii
Pathway
cst00290
Valine, leucine and isoleucine biosynthesis
cst00620
Pyruvate metabolism
cst01100
Metabolic pathways
cst01110
Biosynthesis of secondary metabolites
cst01210
2-Oxocarboxylic acid metabolism
cst01230
Biosynthesis of amino acids
Module
cst_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cst00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CLOST_0414 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CLOST_0414 (leuA)
Enzymes [BR:
cst01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CLOST_0414 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
COMMD9_HN
Motif
Other DBs
NCBI-ProteinID:
CBH20544
UniProt:
E3PVH7
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All DBs
Position
486671..488374
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AA seq
567 aa
AA seq
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MNYKKYKGYETIVLEDRNWPSRKIEKAPQWCSVDLRDGNQALITPMGLKQKLRFFEYLVK
MGFKTIEIGFPAASDTEYEFTRTLIEEGYIPEDVTIQVLTQSRIQIINKTFEALKGTKNA
VVHLYNSTSTLQREVVFRNSKEETIELAVFGARAIKELALKNPETNFTFEYSPESFTGTE
MDFAAEICNSVIDVWKPTKDKKVIINLPSTVEMATPNTYADQIEYMCRNLKSRENIIVSL
HAHNDRGTGVAATELGLMAGADRVEGTLFGNGERTGNADILNLGMNLYTQGINPELDFSD
INSMIEIYEESTAMNVHPRHPYAGDLVFTAFSGSHQDAIKKGMARMNKQAQYWEVPYLPL
DPKDIGKSYEPIIRINSQSGKGGVSFILEQNYGLYIPKDFQKDAGRVITAYSDKMQTEIG
AEEIYEVFLNEYVDIRTPLQLNYHKTQSVDSDWDLVFIEAEIEYNMQKHYVQAEGNGVVS
AFCNSLKEIIGMDIDIVDYRGHSMEYGTKAKAISYIELKNETGERFYGAGTSSSVGKSSL
RAVVSAINKMILAQQTKDMDTQEEDIA
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgaattataaaaaatacaagggatatgaaacgattgtgcttgaggatagaaactggcca
tcgagaaaaatagaaaaagctccgcagtggtgcagtgtggatttaagagatggcaaccaa
gctctcattacacccatgggtttaaaacaaaagctacgtttcttcgaatatttggtcaaa
atgggttttaaaaccatagaaataggttttccagccgcttcagatactgaatatgaattt
acaaggactttaattgaagaaggttacatacctgaggatgttactattcaggtgcttact
caatctagaatccagattataaataaaactttcgaagccttaaagggaactaaaaatgct
gtagtgcatttatataattcaacttcaacgcttcaaagagaggttgtatttagaaatagc
aaagaagaaactatagagcttgcagtgttcggagcaagagcaataaaagagctagcacta
aagaatccagaaacaaattttactttcgagtattcgccagagagctttacagggactgaa
atggattttgctgctgaaatttgcaactctgtaatagatgtgtggaagccgaccaaagat
aagaaagtgattattaatttaccgtctacagtagagatggcaactccaaatacttatgca
gaccaaatagaatacatgtgcagaaatcttaaatctagagaaaatataatagtcagcctt
catgctcacaacgatagaggaactggtgtagcagctactgagctaggcttgatggcagga
gcagatagagttgagggaactttatttggaaatggagaaagaacaggaaacgcagatatt
ttgaatctaggaatgaatttatatactcagggcataaatccagagcttgactttagcgat
attaatagcatgattgagatttatgaggagtctacagctatgaacgttcaccctagacat
ccttacgcaggagacttagtatttactgctttttcaggctcacatcaggatgctatcaaa
aaaggaatggcaagaatgaataaacaagcccagtactgggaagttccttatcttccacta
gatccaaaggatataggaaaaagctatgagccaataattcgtattaattcacaatctggc
aaaggcggagtgagctttatactagaacaaaattacgggctttatattcctaaggatttt
caaaaagatgctggaagagtaattacagcttattccgataagatgcagactgagattggc
gctgaggaaatctatgaggtatttttaaacgaatatgtagatatcagaactccacttcaa
ctgaattaccataagacgcaaagcgtagactctgattgggatttagtttttattgaagct
gagattgaatacaatatgcaaaagcactatgtacaagctgaaggaaatggagttgtttca
gccttttgcaacagcctaaaagaaattattggcatggatattgatatagtagattacaga
gggcactctatggagtatggaactaaggctaaagctatatcgtatatagagctaaaaaat
gaaacaggagaaaggttttatggagctggaacctcaagcagcgtaggaaaatcttcacta
agagctgtagtaagtgcgattaataaaatgattttagctcagcaaactaaggacatggat
actcaggaagaagatatagcataa
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