| Entry |
|
|---|
| Symbol |
HUWE1
|
|---|
| Name |
(RefSeq) E3 ubiquitin-protein ligase HUWE1
|
|---|
| KO |
|
|---|
| Organism |
csum Capricornis sumatraensis (Sumatran serow)
|
|---|
| Pathway |
|
|---|
| Brite |
Enzymes [BR:csum01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
138071169 (HUWE1)
Ubiquitin system [BR:csum04121]
Ubiquitin ligases (E3)
HECT type E3
138071169 (HUWE1)
|
|---|
| SSDB |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
X:complement(91410139..91529841)
|
|---|
| AA seq |
4376 aa
MKVDRTKLKKTPTEAPADCRALIDKLKVCNDEQLLLELQQIKTWNIGKCELYHWVDLLDR
FDGILADAGQTVENMSWMLVCDRPEKEQLKMLLLAVLNFTALLIEYSFSRHLYSSIEHLT
TLLASSDMQVVLAVLNLLYVFSKRSNYITRLGSDKRTPLLTRLQHLAESWGGKENGFGLA
ECCRDLHMMKYPPSATTLHFEFYADPGAEVKIEKRTSSNTLHYIHIEQLDKISESPSEIM
ESLTKMYSIPKDKQMLLFTHIRLAHGFSNHRKRLQAVQARLHAISILVYSNALQESANSI
LYNGLIEELVDVLQITDKQLMEIKAASLRTLTSIVHLERTPKLSSIIDCTGTASYHGFLP
VLVRNCIQAMIDPSMDPYPHQFATALFSFLYHLASYDAGGEALVSCGMMEALLKVIKFLG
DEQDQITFVTRAVRVVDLITNLDMAAFQSHSGLSIFIYRLEHEVDLCRKECPFVIKPKIQ
RPSTAQEGEEMETDMDGVQCIPQRAALLKSMLNFLKKAIQDPAFSDGIRHVMDGSLPTSL
KHIISNAEYYGPSLFLLATEVVTVFVFQEPSLLSSLQDNGLTDVMLHALLIKDVPATREV
LGSLPNVFSALCLNARGLQSFVQCQPFERLFKVLLSPDYLPAMRRRRSSDPLGDTASNLG
SAVDELMRHQPTLKTDATTAIIKLLEEICNLGRDPKYICQKPSIQKADGTAAAPPPRSNH
AAEEASSEDEEEEEVQAMQSFNSTQQNETEPNQQVVGTEERIPIPLMDYILNVMKFVESI
LSNNTTDDHCQEFVNQKGLLPLVTILGLPNLPIDFPTSAACQAVAGVCKSILTLSHEPKV
LQEGLLQLDSILSSLEPLHRPIESPGGSVLLRELACAGNVADATLSAQATPLLHALTAAH
AYIMMFVHTCRVGQSEIRSISINQWGSQLGLSVLSKLSQLYCSLVWESTVLLSLCTPNSL
PSGCEFGQADMQKLVPKDEKTGTTQGGKRSDGEQDGTTGSMDASTQGLLEGIGLDGDTLA
PMETDEPTASDSKGKSKITPAMAARIKQIKPLLSASSRLGRALAELFGLLVKLCVGSPVR
QRRSHHAASTTTAPTPAARSTASALTKLLTKGLSWQPPPYTPTPRFRLTFFICSVGFTSP
MLFDERKYPYHLMLQKFLCSGGHNALFETFNWALSMGGKVPVAEGLEHSDLPDGTGEFLD
AWLMLVEKMVNPTTVLESPHSLPAKLPGGVQNFPQFSALRFLVVTQKAAFTCIKNLWNRK
PLKVYGGRMAESMLAILCHILRGEPVIRERLSKEKEGSRGEEDTGQEEGGSRREPQVNQQ
QLQQLMDMGFTREHAMEALLNTSTMEQATEYLLTHPPPIMGGVVRDLSMSEEDQMMRAIA
MSLGQDIPMDQRAESPEEVACRKEEEERKAREKQEEEEAKCLEKFQDADPLEQDELHTFT
DTMLPGCFHLLDELPDTVYRVCDLIMTAIKRNGADYRDMILKQVVNQVWEAADVLIKAAL
PLTTSDTKTVSEWISQMATLPQASNLATRILLLTLLFEELKLPCAWVVESSGILNVLIKL
LEVVQPCLQAAKEQKEVQTPKWITPVLLLIDFYEKTAISSKRRAQMTKYLQSNNNNWRWF
DDRSGRWCSYSASNNSTIDSAWKSGETSVRFTAGRRRYTVQFTTMVQVNEETGNRRPVML
TLLRVPRLNKNSKNSNGQELEKTLEESKEMDIKRKENKTSDTPLALDSTNTEKETSLEET
KIGEILIQGLTEDMVTVLIRACVSMLGVPVDPDTLHATLRLCLRLTRDHKYAMMFAELKS
TRMILNLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVVRSAATSGAGSTTSGVVSG
SLGSREINYILRVLGPAACRNPDIFTEVANCCIRIALPAPRGSGTASDDEFENLRIKGPN
AVQLVKTTPLKPSPLPVIPDTIKEVIYDMLNALAAYHAPEEADKSDPKPGGMTQEVGQLL
QDMGDDVYQQYRSLTRQSSDFDTQSGFSINSQVFAADGSSTETSTSGASQGEVSTPEESR
DGKKDKEGDRASEEGKQKGKGSKPLMPTSTILRLLAELVRSYVGIATLIANYSYTVGQSE
LIKEDCSVLAFVLDHLLPHTQNAEDKDTPALARLFLASLAASGSGTDAQVALVNEVKAAL
GRALAMAESTEKHARLQAVMCIISTIMESCPSTSSFYSSATAKTQHNGMNNIIRLFLKKG
LVNDLARVPHSLDLSSPNMANTVNAALKPLETLSRIVNQPSSLFGSKSASSKSKSEQDAQ
GAAQDSNSNQQDPGEPGEAEVQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLSSQ
EMQVENELEDLIDELLERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQANR
EDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDD
DGSEMELDEDYPDMNASPLVRFERFDREDDLIIEFDNMFSSATDIPPSPGNIPTTHPLMV
RHADHSSLTLGSGSSTTRLTQGIGRSQRTLRQLTANTGHTIHVHYPGNRQPNPPLILQRL
LGPSAAADILQLSSSLPLQSRGRARLLVGNDDVHIIARSDDELLDDFFHDQSTATSQAGT
LSSIPTALTRWTEECKVLDAESMHDCVSVVKVPIVNHLEFLRDEELEERREKRRKQLAEE
ETKITDKGKEDKENRDQSAQCAASKTNDSTEQNLSDGTPMPDSYPATPSSTDVATSEPRE
TLVTLQPSQQQPTLPTPPALGEIPQELQSPIGEGGSSTQLLMPVEPEELGPTRPSGEAET
TQMELSPAPTITSLSPERAEDSDALTAVSSQLEGSPMDTSSLASCTLEEAVGDAPATGSS
EQPTAGSSTPGDAPPVVTEVQGRGDGSGEPTQPPEDSSPPASSESSSTRDSAVAISGADS
RGILEEPLPSTSSEEEDPLAGISLPEGVDPSFLAALPDDIRREVLQNQLGIRPPTRTAPS
TNNSAPAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQQRRELAQNASSDTPMDPVT
FIQTLPSDLRRSVLEDMEDSVLAVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSA
LSAILRSPAFTSRLSGNRGVQYTRLAVQRGGTFQMGGSSSHNRPSGSNVDTLLRLRGRLL
LDHEALSCLLVLLFVDEPKLNTSRLHRVLRNLCYHAQTRHWVIRSLLSILQRSSESELCI
ETPKLSSSEEKGKKSSKSCGSSSHENRPLDLLHKMESKSSNQLSWLSVSMDAALGCRTNI
FQIQRSGGRKHTEKHASSGSTVHIHPQAAPVVCRHVLDTLIQLAKVFPSHFTQQRTKETN
CESDRERGSKACSPCSSQSTSSGICTDFWDLLVKLDNMNVSRKGKNSVKSVPVSAGGEGE
TSPYSLEASPLGQLMNMLSHPVIRRSSLLTEKLLRLLSLISIALPENKVSEAQANSGSSA
SSTTVATSTTSTTTITATSSTSTPPAATTPVTSVPALVAATAISTIAVAASTTVTTPTTA
TTTVSTATTTKASKSPAKVGDISNSSSSTDFKMVSSGLTENQLQLSVEVLTSHSCSEEGL
EDAANVLLQLSRGDPGTRDTVLKLLLNGARHLGYTLCKQIGTLLAELREYNLEQQRRAQC
ETLSPDGLPEEQPQTTKLKGKMQSRFDVAENVVIVASQKRPLGGRELQLPSMSMLTSKTS
TQKFFLRVLQVIIQLRDDTRRANKKAKQTGRLGSSGLGSASSIQAAVRQLEAEADAIIQM
VREGQRARRQQQAATSESSQSEASVRREESPMDVDQPSPSAQDTQSIASDGTPQGEKEKE
ERPPELPLLSEQLNLDELWDMLGECLKELEESHDQHAVLVLQPAVEAFFLVHATERESKP
PVRDTRESQLAHIKDEPPPLSPAPLTPATPSSLDPFFSREPSSMHISSSLPPDTQKFLRF
AETHRTVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMA
VHVRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMY
ALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILG
KSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANILV
TEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTID
IDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMN
GIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGLA |
|---|
| NT seq |
13131 nt +upstreamnt +downstreamnt
atgaaagtagacaggactaaactgaaaaagactcctactgaggctcctgcagactgcaga
gccttaatagacaaactcaaagtttgtaatgatgagcaacttcttttggaactgcagcag
atcaaaacatggaacattggaaagtgcgagttatatcactgggtggatctgttggaccgc
ttcgatgggattctggcagatgctggacagacagtggagaatatgtcatggatgctcgtg
tgtgataggccggaaaaagaacaactgaaaatgcttctcttggctgtgttgaacttcaca
gccttactcattgagtacagcttttcccggcatctgtatagttccatagagcacttgaca
actttattggcttcttctgatatgcaagtggtgctggcagtcctcaaccttctgtatgtg
tttagcaaaagatcaaattatatcacacgccttggatctgacaagagaactccactgcta
acccggcttcagcatttggcagagagctggggtggtaaggagaatggctttggactagca
gaatgttgcagagatttgcatatgatgaaatacccacccagtgccactacactacacttt
gaattctatgcagaccctggggctgaagtcaaaatcgagaaaaggacatctagtaacaca
ctacattatattcacatagagcaacttgacaagatttcagaaagcccttctgaaatcatg
gagtctcttaccaaaatgtacagcattcctaaggataagcagatgctgttatttacacac
atacggctggcccatggcttttctaatcacaggaagcgattgcaagctgttcaggccagg
ctacatgcaatatctatattagtgtattccaatgccttgcaggagtcagcaaacagtatc
ttgtataatgggttgatagaggagttggtagatgtccttcagataacagataagcagctt
atggagattaaagctgcttctttacgaacgttaacatcaattgtccacttggagagaact
cccaaactcagcagtattattgactgtactggaactgcctcctaccatggatttttgcct
gtacttgtgcgaaactgtatccaagccatgattgacccttccatggatccataccctcac
cagtttgccactgctctcttctcttttttataccatctggccagctacgatgctggtggc
gaagccttggtctcctgtggaatgatggaagccttattgaaggtcataaagtttcttggc
gatgaacaggaccagataacatttgtcaccagagctgtcagagtggttgaccttatcacc
aacctggacatggcagcttttcaatcccatagtggactttctatcttcatttatagactt
gagcatgaagttgatttgtgccgaaaagaatgcccttttgtgatcaagccaaagatccag
agacccagtactgcacaagaaggagaagaaatggaaactgatatggatggagtccagtgt
attccacaacgagccgcacttctcaaatccatgttgaatttcctcaagaaggccattcaa
gaccctgctttctcagatggcatacgacatgtgatggatggttctctgcctacctccctg
aaacacatcatcagcaatgcagaatactatggcccatcactctttctcctagctactgaa
gtggtgactgtgtttgtatttcaagaaccatcattgctttcctcactccaggacaatgga
ttgacagatgtcatgctacatgcactgcttatcaaagacgttcctgctacccgtgaagtt
cttggctccctcccaaatgtattcagtgcactctgcttgaatgcccgaggtctgcagtca
tttgtacagtgtcagccttttgaacgtctcttcaaagttctcctgtctccagattacctc
ccagccatgcggaggaggaggagttctgatcctttaggggatactgcctccaacctagga
agtgctgtagatgagctcatgagacatcagcctaccctcaaaacagatgcaacaactgcg
atcatcaagttacttgaagaaatctgtaatcttggaagagaccctaaatacatctgtcag
aagccatcaatccagaaggcagatggcactgctgctgctcctcccccaagatctaaccat
gctgcagaagaggcctctagtgaggatgaggaggaagaggaagtacaggccatgcagagc
tttaattctacccagcagaatgaaactgagcctaatcagcaggttgttggtacagaggag
cgtattcctattcccctcatggattacatccttaatgtgatgaaatttgtggaatctatt
ctgagcaacaatacaactgatgaccactgccaggaatttgtgaatcagaaaggactcttg
cctttggttaccattttgggtcttcccaatctgcccattgactttcccacatctgcagcc
tgtcaggctgttgcaggtgtctgcaaatccatattgacactgtcacatgaacccaaagtc
ctccaggaaggtctccttcagttggactccattctttcctccttggagccgttacaccgc
ccaatagaatcccccgggggctcagtgttgttgcgagaactggcttgtgctggcaatgtt
gctgatgctaccctctcagctcaagctacacctctactacatgcactcactgctgcccac
gcttacatcatgatgtttgttcatacttgcagggttggacagagtgaaattcgttccatc
tccataaaccagtggggctctcagttgggtctgagtgttctgagcaagctgagccagtta
tactgttccctggtatgggaaagcactgtcctcctctccctctgtaccccaaacagcttg
ccatctgggtgtgaatttggccaggcagacatgcagaaactggttccaaaggatgagaag
acaggtacgacccagggcggaaaaagatcagatggggaacaggatggaaccactggaagt
atggatgcttctacccagggcttgttggaaggcattgggcttgatggtgacacactggct
cctatggagacagacgaacctactgcttcggactctaagggcaaatctaaaatcacacct
gccatggctgccagaatcaagcaaatcaagccattgttgtcagcttcctctagattaggc
agagcactggctgagctgtttggactccttgttaaactttgtgtggggtctcctgtccgc
cagagaagaagccatcatgctgccagcaccaccacagcaccaacacctgctgctcgatca
acggcctcagcccttactaagctcctcacaaaaggcttatcatggcagcctccaccatat
acacctactccacgcttcaggctgaccttcttcatctgttcagttggttttacatcccca
atgctgtttgatgagaggaagtatccctaccacctcatgctgcagaaatttctctgctct
ggaggccacaatgccctttttgaaacattcaattgggctctgtctatgggaggaaaagtt
cctgttgctgagggattagaacattcagacttacctgatggcacaggagaattcctagat
gcctggctaatgctggtggagaagatggtaaatcccaccacggtgcttgaatctccacat
tcactgcctgccaaattgcctggaggtgttcagaactttccacagttcagtgccctccgc
ttccttgtggtaactcagaaggcagcgtttacttgcatcaagaacctgtggaatcggaaa
cccttgaaagtgtatggtgggcgaatggctgagtccatgctagccatcctgtgtcacatc
ctccgaggggaacctgtgattcgagagagactgagcaaagaaaaggagggatctcgagga
gaagaggatacaggacaagaagaaggtggctctcgccgggaacctcaagtcaaccagcaa
caactacaacagctcatggacatgggcttcacaagggaacatgccatggaggccctgttg
aacaccagcaccatggagcaggccacagagtaccttctaacccaccctcccccgatcatg
ggaggagttgttcgggatctgagtatgtctgaagaggaccagatgatgagagcgattgcc
atgtctctgggacaggatatcccaatggatcaaagggcagagtcacctgaggaagttgct
tgccgaaaggaagaggaggaacggaaagctcgagaaaagcaagaagaggaagaggctaaa
tgtctagagaagttccaggatgctgatccattggagcaagatgagctccacactttcaca
gatacaatgttgccaggctgctttcaccttcttgatgagttgccagacactgtataccga
gtgtgtgatttgatcatgacagcaatcaaacgaaatggagcagactatcgagacatgatt
ctgaagcaagtagtcaatcaggtgtgggaagctgctgatgtattgatcaaagctgctctt
cccctgacaacaagtgacacaaaaactgtatcagagtggatcagtcagatggccactcta
ccccaggcctctaatttggccactagaatcttgcttttaacactgctttttgaggaattg
aagctaccttgtgcttgggtggttgaatctagtggcatccttaatgtcctaatcaaactc
ttggaagtggttcagccctgcctacaggccgccaaggaacaaaaggaggtccagacccca
aagtggatcactccagtgttgctcctgattgatttctatgaaaaaacagccatttcctca
aagaggagagcccaaatgactaagtacctacagtctaacaacaacaactggcgctggttt
gatgaccgctctggacgttggtgtagttacagtgcaagcaacaacagcactattgattct
gcctggaaatctggagagacaagtgtgcgtttcactgcaggccgcagaagatacactgtc
cagttcactacaatggtacaggttaatgaggaaacagggaaccggcgtcctgtgatgctg
acactcctgagggtaccacgattgaataaaaattctaaaaacagcaatggacaggaacta
gagaagacactggaagaaagcaaagaaatggatatcaaacgtaaagaaaataaaaccagt
gatacccccttggccctagacagtacaaatactgaaaaggagacaagcctggaagaaaca
aaaattggggagatcttgatccagggcctgacagaggatatggtgactgttttaatccgg
gcctgtgtgagcatgctaggcgtccctgtggatccagacactttgcatgccacccttcgc
ctatgcctgaggctcacccgagaccacaaatatgccatgatgtttgcagagctgaagagt
actcgcatgatcttaaatttgacccagagttcaggcttcaatgggtttactcccctggtc
acccttctcttaagacacatcattgaggacccctgcaccctgcgccataccatggaaaag
gtggttcgctcagcagctacaagtggagctggtagcactacctctggtgttgtatctggc
agcctcggctctcgggagatcaactacatccttcgtgtccttggaccagccgcatgccgc
aacccagacattttcacagaagtggccaactgctgtatccgcattgcccttccagcccct
cgcggctcaggaactgcttcagatgatgagtttgagaatctcagaattaaaggcccgaat
gctgtacagctggtgaaaacaacccctttgaagccctcacctctgcctgtcattcctgat
actatcaaggaagtgatctatgacatgctaaatgccctggctgcataccatgctccagag
gaagcagacaaatctgatcctaaaccagggggtatgactcaagaggttggccagctcctg
caagacatgggtgatgacgtataccagcagtaccggtcacttacccgtcagagcagtgac
tttgatacacagtcaggattttccattaatagtcaggtctttgctgcagatggttcctcc
actgagacttccacatctggggcatcccaaggagaagtgtcaactccagaggagtctcgg
gatgggaagaaagataaagaaggggaccgggcctctgaggaaggcaagcagaaaggcaag
ggcagcaaacctttaatgcccacctccactattcttcggcttctggcagagttggtgaga
tcctatgttggtattgctacgctgattgccaactacagctacactgtgggccagtctgag
ctgatcaaagaggactgcagtgtgctagcttttgtcttggaccacctcctcccacatacc
cagaatgcagaagacaaggacacacctgcgctggctcgcctgttccttgcaagcctggct
gcctcagggagtggcacagatgcccaggtggcccttgtgaatgaagtaaaagcagccctg
ggaagggcactggctatggctgagagtacagagaaacatgccagacttcaggcagtgatg
tgtatcatcagtactatcatggagtcctgcccctccacctccagcttctacagcagtgca
acagccaagacccaacacaatggcatgaacaacatcattcgactcttcctgaagaaggga
ctggttaatgacctggccagagtgcctcacagcctggacctgtccagtcccaacatggcc
aacacagtcaatgctgctctgaagcctttggaaacactttcccggattgtgaaccagccc
agtagcctttttggcagtaagagtgcttctagcaagagcaagtctgagcaggatgcccaa
ggagctgctcaggactctaatagcaaccaacaggacccaggcgagcctggggaagcagaa
gtgcaggaggaggatcatgatgtcactcagacagaggtggcagatggggatatcatggat
ggggaggctgaaaccgactcagtggtgattgctgggcagcctgaggtgctcagttcacaa
gagatgcaggttgagaatgagctggaggacctgatagatgagttgcttgagagggatggc
ggatctgggaacagtacaattatagtgagcagaagtggagaggatgaatcacaagaggac
gtgctgatggatgaagctccttccaacctcagccaagcttccaccttgcaggccaaccga
gaagattccatgaatatcctggaccctgaggatgaggaggagcacactcaggaagaggac
agcagtggcagtaacgaggatgaggatgatagtcaggatgaagaggaggaggaggaggaa
gatgaggaagatgatcaggaggatgatgaaggtgaagagggagatgaagacgatgacgac
gatggctctgaaatggaattggatgaggattaccctgatatgaacgcttctcccttggtc
cgatttgagcgctttgaccgggaggatgatctcatcattgagtttgacaacatgttctcc
agtgctacagacatccccccatccccaggaaatatccctaccacccacccactgatggta
cgccatgcagatcacagttccctgacactgggcagtggctcctctacaacacgtctcacc
cagggcattgggcgcagtcagaggaccctgagacagctgacggccaacacaggccatacc
attcacgttcactaccctgggaatcgccagcccaatcctcctcttatactccagaggttg
cttggtccctctgctgctgctgacatccttcagctgagcagcagccttcccctgcaaagc
cgaggccgagcccgcctcctagtgggcaacgatgacgtccacatcatcgcccggtctgat
gatgaactactggatgactttttccatgatcagagcacagctaccagccaagcagggact
ctatccagtatccctacagccttgactcgctggacagaggaatgcaaagttcttgatgct
gagagcatgcatgactgtgtttcagttgttaaagtgcccattgtcaatcatctggaattc
ctgagggatgaggagctggaagaaaggagggagaaaaggaggaaacaactagctgaggaa
gaaacaaagataaccgacaaaggcaaagaagataaggagaacagggatcagagtgcacag
tgtgctgcatctaagacaaatgactccactgaacagaacctctcagatgggactcctatg
cctgacagctacccagcaaccccatcttcaactgatgtagctacatctgagcccagggag
acccttgtcactctgcagccctcccaacagcaaccaacactccccaccccaccagctttg
ggagagattcctcaagagctgcagtccccaattggagaaggtgggagctctacacagcta
ttgatgcctgtagagccagaggaattgggtcccacaaggccaagtggagaagcagaaaca
actcagatggagctatccccagctcccactataacctctctttccccagagagagctgaa
gattctgatgctctgacagctgtcagcagtcaactggaaggctctcccatggatactagc
agcctggcttcctgtaccctggaggaggctgtgggtgacgccccagcaactggcagttct
gagcagcccacagcaggcagctccactcctggggatgccccaccagttgtgacagaagta
caaggcaggggtgatgggtcaggggaacctacccagccccctgaggacagctctccccct
gcatcctctgagagttcttccaccagagattccgcagtggccatttctggagcagattcc
cggggaatcctggaagagccattgccttcaacaagcagtgaagaagaagatcctcttgca
ggtattagtctccccgaaggtgtggacccctcttttctggccgccctgcctgatgacatt
cgccgagaagtcctacagaaccagctgggcattcgtccaccaacacgaactgccccctca
acaaataactcagctcctgcagtggtggggaatcctggtgtcaccgaagtgagccctgag
ttcctggctgccctgcctccagccatccaggaggaagtactggcacagcagagagctgag
caacaacgacgggaactagcacaaaatgccagctcagacacccccatggaccctgtgacc
ttcatccagactctgccctcagacctacgccgtagtgtcctagaggatatggaggacagt
gtgttggccgtgatgccacctgacattgcagctgaagctcaagccctgaggcgagagcag
gaagcccggcagaggcagctcatgcatgagcggctttttgggcacagcagcacctctgca
ctctctgccattctccgaagcccagccttcaccagtcgcctgagtggcaaccgtggggtc
caatacactcgccttgctgtgcaaagaggtggcaccttccagatggggggtagcagcagc
cataataggccttctggcagtaatgtggacaccctcctacgtctccgaggacggctcctc
ctggatcacgaagccctgtcttgtctcctggtcctactttttgtggatgagccaaaactc
aatactagccgtcttcaccgagtactgagaaatctctgctaccatgcccagacccgccac
tgggttatccgtagcctgctttccatcttgcagcgcagcagtgagagtgagctttgcatt
gaaacacccaagctctcctcaagtgaggaaaagggcaaaaagtcaagcaagagctgtggg
tcaagcagccatgagaaccggcccctggacctgctacacaagatggagtctaagagttcc
aaccagctttcctggctctcagtatccatggatgcagccctaggctgcaggactaatata
ttccagatccagcgttcagggggtcgcaaacatactgagaaacatgcaagtagtggctcc
actgtccatatccacccccaggctgctcctgttgtctgcagacacgttctggatacactc
attcaattggccaaggtgtttcccagtcacttcacacagcagcggaccaaagaaacaaac
tgtgagagtgatcgggagaggggcagtaaggcctgcagcccatgctcttcacagtccaca
agcagtggcatttgcacagacttctgggacttattggtaaaactggacaacatgaatgtc
agccggaaaggcaagaactccgtgaagtcagtgccagtgagcgctggtggtgagggggaa
acctccccatacagcctcgaagcctctccactggggcaactcatgaacatgttgtcacac
ccagtcatccgccggagctctctcttaactgagaagctcctcagactcctttctctcatc
tcaattgctctcccagaaaacaaagtgtcggaagcacaggctaattctggcagcagtgct
tcctccaccactgttgccacctcaaccacatctaccaccactatcactgccacctccagc
acgtccactccgcctgctgcaaccacccctgtcacttctgttccagccctggttgctgcc
acggctatatccaccattgccgtagccgcttcaaccacagtgactacccccacaactgct
accactactgtttcaactgctactactactaaggccagcaaatctccagctaaagttggt
gatatcagcaacagcagcagcagcacagactttaagatggtatcctctggcctcactgaa
aatcagctccagctctctgtggaagtgttgacatcccattcgtgttctgaagaaggccta
gaggatgcagcaaatgtgttactgcagctctctcggggggaccctgggacccgggacact
gttttgaagttgctactgaatggagcccgccatctgggttatacgctttgtaaacagata
ggaactcttctggctgagctacgggaatacaatctggaacagcagcggcgagcccagtgt
gaaaccctctcccctgatggcctgcctgaggaacagccacagaccaccaagctgaaaggc
aaaatgcagagcaggtttgacgtggctgagaatgtggtaatcgtggcatctcagaagcgg
cctctgggtggccgggagctccaactgccttctatgtccatgttgacatccaagacatct
acccagaagttcttcttgagggtactgcaggtcatcatccagcttcgggatgacacacgc
cgtgctaacaagaaggccaagcagacaggcaggctaggttcctccggtttaggctcagct
agcagcatccaggcagctgttcggcagctggaggctgaggctgatgccattatacaaatg
gtacgtgagggtcagagggcgcggagacagcaacaagcagcaacgtcggagtcaagccag
tcagaggcatctgtccgaagggaggagtcacccatggatgtggaccagccatctcccagt
gctcaagatactcagtccattgcctcagatggaactccacagggggagaaggagaaggag
gaaaggccacctgagttacccctgctcagtgagcagctgaacttggatgagctgtgggac
atgctgggagagtgtctaaaggaactggaggaatcccatgaccagcatgcggtgctagtg
ctacaacctgctgtcgaggccttctttctggtccatgcaacagagcgggagagcaagcct
cctgtccgggacacccgtgagagccagctggcacacatcaaggacgagccacctccactc
tcccctgcccctttaaccccagccactccttcctcccttgacccgttcttctcccgggag
ccctcatctatgcacatctcctcaagcctgccccctgacacacagaagtttcttcgcttt
gcagagactcatcgcactgtgttaaaccagatcctacggcagtccaccacccacctcgct
gatgggccttttgctgtcctggtagactacattcgtgtcctcgactttgatgtcaagcgc
aaatatttccgccaagagctggagcgtttggatgagggactccggaaagaagacatggct
gtgcacgttcgtcgtgaccatgtctttgaagactcctatcgtgagctgcaccggaaatcg
cctgaagaaatgaagaatcgattgtatatagtatttgaaggagaagaagggcaggatgct
ggagggctcctccgggagtggtatatgatcatctctcgggagatgtttaaccctatgtat
gccttgttccgtacctcacctggtgatcgggtcacatacaccatcaatccatcttcccac
tgcaaccccaaccacctcagctacttcaagtttgttggacgcatcgtggccaaagctgtg
tatgacaaccgcctcctggagtgctactttactcggtccttctacaaacacattttgggc
aagtctgtcagatatacagatatggagagtgaagactaccacttctaccagggtctggtt
tatctgctggaaaatgatgtatccacattaggctatgatctcaccttcagcactgaggtc
caagagtttggagtctgtgaagttcgtgacctcaaacccaatggggccaacatcttggta
acagaggaaaataagaaggaatatgtacacctggtgtgccagatgagaatgacaggagcc
atccgcaaacagctggcggctttcttagaaggtttctatgagatcattccaaagcgcctc
atttcaatcttcactgagcaagagttagagctgctcatatcaggactgcccacaatcgac
attgacgatttgaaatctaacactgaatatcacaagtaccagtccaactctattcagatc
cagtggttctggagagcattgcgttctttcgatcaagctgaccgtgccaagttcctccag
tttgtcacaggtacttccaaggtgcccctgcaaggttttgctgcccttgaaggcatgaat
ggcattcagaagtttcaaatccatcgagatgacaggtccacagaccgcctgccttcagct
cacacatgttttaatcagctggacctgcctgcctatgagagctttgagaagctccgccac
atgctactattggccatccaggagtgctctgaaggctttgggctggcctaa |
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