Capricornis sumatraensis (Sumatran serow): 138072822
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Entry
138072822 CDS
T10522
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
csum Capricornis sumatraensis (Sumatran serow)
Pathway
csum01521
EGFR tyrosine kinase inhibitor resistance
csum01522
Endocrine resistance
csum04010
MAPK signaling pathway
csum04012
ErbB signaling pathway
csum04014
Ras signaling pathway
csum04062
Chemokine signaling pathway
csum04068
FoxO signaling pathway
csum04072
Phospholipase D signaling pathway
csum04150
mTOR signaling pathway
csum04151
PI3K-Akt signaling pathway
csum04510
Focal adhesion
csum04540
Gap junction
csum04630
JAK-STAT signaling pathway
csum04650
Natural killer cell mediated cytotoxicity
csum04660
T cell receptor signaling pathway
csum04662
B cell receptor signaling pathway
csum04664
Fc epsilon RI signaling pathway
csum04714
Thermogenesis
csum04722
Neurotrophin signaling pathway
csum04810
Regulation of actin cytoskeleton
csum04910
Insulin signaling pathway
csum04912
GnRH signaling pathway
csum04915
Estrogen signaling pathway
csum04917
Prolactin signaling pathway
csum04926
Relaxin signaling pathway
csum04935
Growth hormone synthesis, secretion and action
csum05034
Alcoholism
csum05160
Hepatitis C
csum05161
Hepatitis B
csum05163
Human cytomegalovirus infection
csum05165
Human papillomavirus infection
csum05200
Pathways in cancer
csum05205
Proteoglycans in cancer
csum05206
MicroRNAs in cancer
csum05207
Chemical carcinogenesis - receptor activation
csum05208
Chemical carcinogenesis - reactive oxygen species
csum05210
Colorectal cancer
csum05211
Renal cell carcinoma
csum05213
Endometrial cancer
csum05214
Glioma
csum05215
Prostate cancer
csum05220
Chronic myeloid leukemia
csum05221
Acute myeloid leukemia
csum05223
Non-small cell lung cancer
csum05224
Breast cancer
csum05225
Hepatocellular carcinoma
csum05226
Gastric cancer
csum05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
csum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
138072822 (SOS2)
04012 ErbB signaling pathway
138072822 (SOS2)
04014 Ras signaling pathway
138072822 (SOS2)
04630 JAK-STAT signaling pathway
138072822 (SOS2)
04068 FoxO signaling pathway
138072822 (SOS2)
04072 Phospholipase D signaling pathway
138072822 (SOS2)
04151 PI3K-Akt signaling pathway
138072822 (SOS2)
04150 mTOR signaling pathway
138072822 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
138072822 (SOS2)
04540 Gap junction
138072822 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
138072822 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
138072822 (SOS2)
04660 T cell receptor signaling pathway
138072822 (SOS2)
04662 B cell receptor signaling pathway
138072822 (SOS2)
04664 Fc epsilon RI signaling pathway
138072822 (SOS2)
04062 Chemokine signaling pathway
138072822 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
138072822 (SOS2)
04912 GnRH signaling pathway
138072822 (SOS2)
04915 Estrogen signaling pathway
138072822 (SOS2)
04917 Prolactin signaling pathway
138072822 (SOS2)
04926 Relaxin signaling pathway
138072822 (SOS2)
04935 Growth hormone synthesis, secretion and action
138072822 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
138072822 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
138072822 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
138072822 (SOS2)
05206 MicroRNAs in cancer
138072822 (SOS2)
05205 Proteoglycans in cancer
138072822 (SOS2)
05207 Chemical carcinogenesis - receptor activation
138072822 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
138072822 (SOS2)
05231 Choline metabolism in cancer
138072822 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
138072822 (SOS2)
05225 Hepatocellular carcinoma
138072822 (SOS2)
05226 Gastric cancer
138072822 (SOS2)
05214 Glioma
138072822 (SOS2)
05221 Acute myeloid leukemia
138072822 (SOS2)
05220 Chronic myeloid leukemia
138072822 (SOS2)
05211 Renal cell carcinoma
138072822 (SOS2)
05215 Prostate cancer
138072822 (SOS2)
05213 Endometrial cancer
138072822 (SOS2)
05224 Breast cancer
138072822 (SOS2)
05223 Non-small cell lung cancer
138072822 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
138072822 (SOS2)
05160 Hepatitis C
138072822 (SOS2)
05163 Human cytomegalovirus infection
138072822 (SOS2)
05165 Human papillomavirus infection
138072822 (SOS2)
09165 Substance dependence
05034 Alcoholism
138072822 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
138072822 (SOS2)
01522 Endocrine resistance
138072822 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_19
Motif
Other DBs
NCBI-GeneID:
138072822
NCBI-ProteinID:
XP_068820147
LinkDB
All DBs
Position
2:59476415..59577202
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFYSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKI
CSEEHEDRECLNQAITALMNLQGSMDRIYKQFSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
CSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIYAAKSAEEKNNWMAALI
SLQYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLTERFEIPEPEPTEADKLA
LEKGEQPISTDLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLEFFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
DAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGCASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSAFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDQDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPAPTGPFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVNTCPNSPN
TPPSTPSPRVPRRCYVLSSSQNNLAHLQAPPVPPRQNSSPLLPKLPPKTYKRELSHPPMY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccttacgagttctacagcgaagagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaaagaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactaccatgtatccctgtatattgtggctgtgctagagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatctcaacaa
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggcttggtttctctttgtgaagatgaacctagttcttcaggcgaattaaactactat
gaccttgttagaactgaaattgcagaagaaagacagtatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcttttctttctgacagaaagctgtttaaaccttctgatatt
gaaaagattttcagtaacattttagatatacatgagttgactgtgaaacttttaggttta
attgaagacacagttgaaatgactgatgaaagtagccctcatcccttagctggcagctgt
tttgaagatctggcagaggagcaagcatttgatccttatgaaacattatcccaggatatt
ctttcaccaaagtttaatgaacattttagtaagttgatggccagacctgcagtggctctg
cactttcagtccattgctgatggttttaaagaggcagttcgttacgtccttccacgcctt
atgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaaata
tgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagtatggaccgaatttacaagcagttttcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagacattggacagtgttgtaat
gaatttattatggaaggcccattgacaagaattggtgctaaacatgaacggcatattttt
ctctttgacggcttaatgatcagctgcaaacccaaccacagccagtcacgcctcccagga
tgcagcagtgcagagtacagactaaaagagaaatttgtcatgaggaagatacagatatgc
gataaagaagatacttgtgagtgcaagcacgcttttgagttagtatccaaagatgaaaac
agcataatatatgctgctaagtctgctgaagagaaaaataactggatggcagcacttatt
tcccttcagtatcgtagtactctggatcgaatgctggattcggtattattgaaggaagaa
aatgaacaaccattgagattaccaagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcagagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaaggctaacatatcatatgtacgcagatcccaat
tttgttcgtacctttcttactacgtatcgttcattttgtaaaccacaggaattactaagc
ttactgactgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
ttagaaaaaggcgagcagcccatcagtacagaccttaaaaggtttcgcaaggaatacgtc
caaccagtacaacttagggtcttaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagacttggagctgcttgaaagactagaattcttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaaaaaacaa
gctcaggcaaatggtataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacgcttttggaatctgatctctacaggaaagttcaaccttct
gaactcgtagggagtgtatggaccaaagaagataaagaaataaactctccaaatttatta
aaaatgattcgccacaccacaaatcttaccctctggtttgaaaaatgcattgtggaggca
gaaaattttgaggaacgggtggcaatactgagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggagatcgtcagtgcagtaaattcagtatca
gtctatagactagatcatacatttgaggcgttgcaggaaagaaaaaggaaaattttggat
gatgctgtggaattaagtcaagatcattttaaaaaatatctagtgaaacttaagtcaatc
aatccaccctgtgtgcctttttttggaatatatttaacaaatatactgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcaaaatcaaccttactgtttacgg
atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggatgtgcttctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa
cagccaccgcgatttcctaggaaatcagctttctccttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggtactttgcgaggtcacccaacaccattagaa
agagaaccgtgtaaaataagctttagtcggattgctgaaacggagcttgaatcaacagtg
tcagcaccaacctctccaaatacaccatctaccccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggaagcaatagcatctttgctcca
gtcctcttgcctcattcaaagtctttcttcagttcgtgtggtagtttacataagctaagt
gaagagccactgattcctcctccacttccacctcgaaaaaaatttgatcaggatgcttca
aattccaagggaactatgaaatctgatgatgacccccctgctattccaccaagacaacct
cctcctccaaaggtaaaacccagagttcctgctcctactggtccatttgatgggcctctg
catagtccacctccaccaccgccgagagatcctcttcctgatacccctccaccggttcca
cttcggcctccagaacactttataaactgtccgtttactcttcagccacctccactggga
catcttcacagagatccagactggttcagagacgttaatacgtgtccaaattctccaaac
actcctcctagcacaccctctccaagggtacctcgtcgatgctatgtgctcagttctagt
caaaataatcttgctcatcttcaagctccccctgttccaccaaggcagaattcaagccct
cttctaccaaaactgccaccaaagacttacaaacgggagctttcacaccccccaatgtat
agactgccattgttagaaaatgcagaaactcctcaatga
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