Capricornis sumatraensis (Sumatran serow): 138073149
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Entry
138073149 CDS
T10522
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
csum Capricornis sumatraensis (Sumatran serow)
Pathway
csum01521
EGFR tyrosine kinase inhibitor resistance
csum01522
Endocrine resistance
csum04010
MAPK signaling pathway
csum04012
ErbB signaling pathway
csum04014
Ras signaling pathway
csum04062
Chemokine signaling pathway
csum04068
FoxO signaling pathway
csum04072
Phospholipase D signaling pathway
csum04150
mTOR signaling pathway
csum04151
PI3K-Akt signaling pathway
csum04510
Focal adhesion
csum04540
Gap junction
csum04630
JAK-STAT signaling pathway
csum04650
Natural killer cell mediated cytotoxicity
csum04660
T cell receptor signaling pathway
csum04662
B cell receptor signaling pathway
csum04664
Fc epsilon RI signaling pathway
csum04714
Thermogenesis
csum04722
Neurotrophin signaling pathway
csum04810
Regulation of actin cytoskeleton
csum04910
Insulin signaling pathway
csum04912
GnRH signaling pathway
csum04915
Estrogen signaling pathway
csum04917
Prolactin signaling pathway
csum04926
Relaxin signaling pathway
csum04935
Growth hormone synthesis, secretion and action
csum05034
Alcoholism
csum05160
Hepatitis C
csum05161
Hepatitis B
csum05163
Human cytomegalovirus infection
csum05165
Human papillomavirus infection
csum05200
Pathways in cancer
csum05205
Proteoglycans in cancer
csum05206
MicroRNAs in cancer
csum05207
Chemical carcinogenesis - receptor activation
csum05208
Chemical carcinogenesis - reactive oxygen species
csum05210
Colorectal cancer
csum05211
Renal cell carcinoma
csum05213
Endometrial cancer
csum05214
Glioma
csum05215
Prostate cancer
csum05220
Chronic myeloid leukemia
csum05221
Acute myeloid leukemia
csum05223
Non-small cell lung cancer
csum05224
Breast cancer
csum05225
Hepatocellular carcinoma
csum05226
Gastric cancer
csum05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
csum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
138073149 (SOS1)
04012 ErbB signaling pathway
138073149 (SOS1)
04014 Ras signaling pathway
138073149 (SOS1)
04630 JAK-STAT signaling pathway
138073149 (SOS1)
04068 FoxO signaling pathway
138073149 (SOS1)
04072 Phospholipase D signaling pathway
138073149 (SOS1)
04151 PI3K-Akt signaling pathway
138073149 (SOS1)
04150 mTOR signaling pathway
138073149 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
138073149 (SOS1)
04540 Gap junction
138073149 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
138073149 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
138073149 (SOS1)
04660 T cell receptor signaling pathway
138073149 (SOS1)
04662 B cell receptor signaling pathway
138073149 (SOS1)
04664 Fc epsilon RI signaling pathway
138073149 (SOS1)
04062 Chemokine signaling pathway
138073149 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
138073149 (SOS1)
04912 GnRH signaling pathway
138073149 (SOS1)
04915 Estrogen signaling pathway
138073149 (SOS1)
04917 Prolactin signaling pathway
138073149 (SOS1)
04926 Relaxin signaling pathway
138073149 (SOS1)
04935 Growth hormone synthesis, secretion and action
138073149 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
138073149 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
138073149 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
138073149 (SOS1)
05206 MicroRNAs in cancer
138073149 (SOS1)
05205 Proteoglycans in cancer
138073149 (SOS1)
05207 Chemical carcinogenesis - receptor activation
138073149 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
138073149 (SOS1)
05231 Choline metabolism in cancer
138073149 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
138073149 (SOS1)
05225 Hepatocellular carcinoma
138073149 (SOS1)
05226 Gastric cancer
138073149 (SOS1)
05214 Glioma
138073149 (SOS1)
05221 Acute myeloid leukemia
138073149 (SOS1)
05220 Chronic myeloid leukemia
138073149 (SOS1)
05211 Renal cell carcinoma
138073149 (SOS1)
05215 Prostate cancer
138073149 (SOS1)
05213 Endometrial cancer
138073149 (SOS1)
05224 Breast cancer
138073149 (SOS1)
05223 Non-small cell lung cancer
138073149 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
138073149 (SOS1)
05160 Hepatitis C
138073149 (SOS1)
05163 Human cytomegalovirus infection
138073149 (SOS1)
05165 Human papillomavirus infection
138073149 (SOS1)
09165 Substance dependence
05034 Alcoholism
138073149 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
138073149 (SOS1)
01522 Endocrine resistance
138073149 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
138073149
NCBI-ProteinID:
XP_068820765
LinkDB
All DBs
Position
1:84892306..85020165
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYNYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TKSTDEVPVPPPVPPRRRPESAPAESSPSKMMSKHLDSPPAIPPRQPTSKAYSPRYSLSD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSVH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcatccaactcttgagtct
agtgatgatgctcttcagtatgttgaagaattaattttgcaactattaaatatgctatgc
caagctcaaccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaatccatcctttgttaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttccgcagac
attttgaagctggtggggaattatgtgcgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgtg
gaagatataaatatattgtctttaactgatgaagagccttccacctcaggagagcagact
tactatgatttggtaaaagcatttatggcagaaattcgacaatacataagggagcttaat
ctaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtggatatacatgaacttagtgtaaaattactg
ggccatatagaagatactgtggaaatgacagatgaaggcagtccccatccattagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattctgcgacctggttttcatgatcgtttccttagtcagttatcaaagcctggagca
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcaatatgttttaccc
aggctacttctagcccctgtttaccactgtctacattacttcgaacttctgaagcagtta
gaagaaaagagtgaggatcaagaagacaaagaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactctaacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagacta
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaagaacaattggatggcagca
ctgatatctttacagtaccggagtaccctggaaagaatgctcgacgtgaccatgctgcag
gaagaaaaggaggagcagatgaggctccctagtgctgacgtttacagatttgcagagcct
gactctgaagaaaatatcatatttgaagaaaacgtgcagcccaaagctgggattccaatt
atcaaggcaggaaccgttattaaacttatagagaggctcacataccacatgtatgcagat
cccaattttgttcggacatttcttacaacatatagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atcgctatagagaatggagaccaacccttgagtgcagaactaaaaagatttagaaaagaa
tatatacagcctgtgcagctgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctatgattttgaaagagatgcagatcttttgcagcgaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatgggccaggtcataatattacatttcagagttcacctcctacg
gttgagtggcacataagcagacctgggcacatcgagacttttgacctgcttaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
ctcctgaaaatgatccggcataccacgaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctacaa
gtgttccaagagctcaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca
tcccctgtttacagactagaccacacgttcgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaactaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggtatttatctcactaatatcctgaaaaca
gaagaaggcaaccctgaggtcctaaaacggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggcgagatccagcagtaccaaaatcagccttactgt
ttacgagtagagtcagatatcaaaaggttttttgaaaacttgaatccaatgggaaatagc
atggaaaaagaatttacggattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctcttccaagatttccaaaaaaatacaactatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtactatgagacatcccacacctctgcagcaagagcca
aggaaaattagttatagcaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtatttgattctgatcattcaagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagagcactgatgaagtgcctgtcccccctcctgttcctccacgaagacggccagag
tctgccccagcagaatcttcgccatctaagatgatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacggtattcactatcagac
cggacctctatatcagaccctcctgagagccctcccttattacctccacgagaacccgtg
aggacacctgatgttttctcaagttcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatagtaatgccttcttcccaaacagcccctccccctttacaccacctcct
cctcaaacaccttctcctcatggaacaagaaggcatctgccatcgccaccattgacacaa
gaagtggacctccattccattgctgggccgcctgttcctccacgacaaagcacttctcag
catatccctaaactccctccaaaaacttacaagagggagcacacccacccgtccgtgcac
agagatggaccaccactgttggagaatgcccattcttcctga
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