Capricornis sumatraensis (Sumatran serow): 138080106
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Entry
138080106 CDS
T10522
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
csum Capricornis sumatraensis (Sumatran serow)
Pathway
csum00790
Folate biosynthesis
csum01100
Metabolic pathways
csum01240
Biosynthesis of cofactors
csum01523
Antifolate resistance
csum04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
csum00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
138080106 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
138080106 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
138080106 (FPGS)
Enzymes [BR:
csum01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
138080106 (FPGS)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
138080106
NCBI-ProteinID:
XP_068829151
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Position
1:complement(8398494..8425779)
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AA seq
583 aa
AA seq
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MRCARPLATCWPVAEKLWWEAAMEEPGLSGCPLSAKTASFQDAVRTLNTLQTNANYLEMV
KRERGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRSYGLKT
GFFSSPHLVQVRERIRINGQPISSELFTKHFWRLYHRLEETKDDSSCVSMPGYFRFLTLM
AFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGITSLGIDHTGLLGDTMEKIAWQKG
GIFKSGVPAFTVLQPDEPLAVLRDRAQQISCPLYLCPPLQALEEGGPPLTLGLEGEHQRS
NAALALQLARCWLQQKGYQDAGELKASRPSLPGQLPPAPVFQPTPHMQQGLRHTEWPGRT
QLLRRGPLTWYLDGAHTTSSMQACVRWFRQALHRCERPDSGSEVLVLLFNSTGDRDSAAL
LKVLQPCQFDYAIFCPNLVEMASTDNADQQNFTVTLDQVLLRCLAHQQHWSRLHEERASP
DPWSTPGQEQGGPASLLLAPHPPHTHGASSLVFSCISHALQWVTQGRDPVFQPPSPPRGL
LAHPVAYSGAMVLQEAAAVHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atgagatgtgccaggcctctggctacttgctggccagttgctgagaagctctggtgggaa
gcagccatggaggagccaggcctatccgggtgtcctctctcggctaaaactgcctccttc
caggatgccgtgcgcacactcaacaccctgcagaccaatgctaactacttggagatggtg
aagcgtgagcggggtgacccccagacacagctggaagccatgaagctgtacttggcacgg
agtgggctgcaggtggaggacttggaccaactgaacattatccacatcactgggaccaag
gggaagggctccacgtgtgccttcactgaacgtatcctccgaagctatggcctgaagacg
gggttctttagctctccccacctggtgcaggtgcgtgagcggatccgcatcaatgggcag
cccataagctccgagctcttcaccaagcacttttggcgcctctaccaccggctggaggag
accaaggacgacagtagctgtgtctccatgcctggctacttccgcttcctcacgctcatg
gccttccacgtcttcctccaagagaaggtggacctggcagtggtggaagtaggcatcggc
ggggcttacgactgcacaaacatcatcaggaagcctgtggtgtgcgggatcacctctctt
ggcattgaccacactggccttctgggggacacgatggagaagatcgcatggcagaaaggg
gggatttttaagagtggcgtccctgccttcaccgtgctccagcctgacgagccgctggca
gtgctaagggacagggctcagcagatctcatgtcccctctacctgtgcccaccactacaa
gccctggaggaaggggggccaccgctgaccctgggcctggagggagagcaccagcggtcc
aatgctgccctggccttgcagctggcccgctgctggctgcagcagaaaggttaccaggat
gctggggagctgaaggcatccaggcccagcctcccggggcagctgcccccagcacctgtg
ttccaacccacgccccacatgcagcaggggcttcggcacacggagtggccaggtcggacg
cagttgctgcggcgcgggccccttacctggtacctggatggcgcgcacaccaccagcagc
atgcaggcctgtgtgcgctggttccgccaggcgctacaccgctgcgagcggccggacagt
gggtccgaggtgctcgtcttgctcttcaactccactggggaccgggattccgcggccctg
ctgaaagtgctgcagccctgccagtttgactatgccattttctgccctaacctggtagag
atggcatcaacagacaatgcagaccaacagaacttcacagtgacactggaccaggtgctg
ctccgctgcctcgcccaccaacagcactggagtcgcctgcatgaggagcgggccagcccg
gacccctggagcacgcccggccaggagcagggtgggcccgcatctctgctgctggcacct
cacccaccccacacccatggtgccagctccctcgtcttcagctgcatctcccacgccttg
cagtgggtcacccaaggccgggaccctgtctttcagccgcccagtcccccacggggcctc
ctcgcccaccctgtggcatatagtggggccatggtactccaagaggctgccgccgtccac
gtgctggtcacaggcagcctgcacctggtgggcggtgtcctgaagctgctggagccctcc
ctgtcccagtag
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