| Entry |
|
|---|
| Symbol |
MTOR
|
|---|
| Name |
(RefSeq) serine/threonine-protein kinase mTOR
|
|---|
| KO |
|
|---|
| Organism |
csum Capricornis sumatraensis (Sumatran serow)
|
|---|
| Pathway |
| csum01521 | EGFR tyrosine kinase inhibitor resistance |
| csum04213 | Longevity regulating pathway - multiple species |
| csum04613 | Neutrophil extracellular trap formation |
| csum04935 | Growth hormone synthesis, secretion and action |
| csum05022 | Pathways of neurodegeneration - multiple diseases |
| csum05167 | Kaposi sarcoma-associated herpesvirus infection |
| csum05170 | Human immunodeficiency virus 1 infection |
| csum05207 | Chemical carcinogenesis - receptor activation |
| csum05230 | Central carbon metabolism in cancer |
| csum05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
|
|---|
| Brite |
Enzymes [BR:csum01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
138090571 (MTOR)
Protein kinases [BR:csum01001]
Serine/threonine kinases: Other
PIKK family [OT]
138090571 (MTOR)
Membrane trafficking [BR:csum04131]
Autophagy
Other autophagy associated proteins
mTORC1 complex
138090571 (MTOR)
mTORC2 complex
138090571 (MTOR)
|
|---|
| SSDB |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
14:49767878..49892703
|
|---|
| AA seq |
2550 aa
MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
KDLMGFGTKPRHITPFTSFQAMQPQQSNALVGLLGYSSHQGLMGFGASPSPAKSTLVESR
CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSVHLISGHAHVVSQTAVQVVADVLSKLL
VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
LWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
VFMHDNSSGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
RHRINHQRYDVLICRIVKGYTLADEEEDPLVYQHRMLRSGQGDALASGPVETGPMKKLHV
STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHF
GELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK
WTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLA
QQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWW
ERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVD
PSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHK
QELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEA
VLHYKHQNQARDEKKKLRHASGANITNAATAATTAATATATATSTEGSNSESEAESTENS
PTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDV
NEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVA
SKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYF
GERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQ
AWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPS
LQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKN
LSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLT
LMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDR
HPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRIT
CHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILD
GVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDETL
DVPTQVELLIKQATSHENLCQCYIGWCPFW |
|---|
| NT seq |
7653 nt +upstreamnt +downstreamnt
atgcttggaaccggccctgccgccgccaccacagctgccaccacatccagcaacgtgagc
gtcctgcagcagtttgccagcggcctaaagagccggaatgaagagaccagggccaaagct
gccaaggagctccagcactacgtcaccatggagctccgagagatgagtcaagaggagtct
actcgcttctatgatcagctgaaccatcacatctttgaactggtgtccagctcagatgcc
aatgagaggaaaggtggcattttggccatagccagcctcataggagtggaaggtgggaat
gccactcggatcggaagatttgctaactaccttcggaacctccttccctccaacgaccca
gttgtcatggagatggcatccaaggccatcggtcggctcgccatggcaggggacactttc
actgccgagtatgtggagtttgaggtgaagcgagccctggaatggctgggtgctgaccgc
aacgagggccgaagacacgcggctgtcctggtgctccgtgagctggccatcagcgtcccc
accttcttcttccagcaagtgcagcccttctttgacaatatctttgtggctgtgtgggac
cccaaacaggccatccgggagggagctgttgccgcccttcgtgcctgtctgatcctcacc
acccagcgggagccaaaagagatgcagaagccgcagtggtacaggcacacgtttgaagaa
gcagagaaagggtttgatgagaccttggccaaggagaagggcatgaatcgggatgaccgg
atccatggagccctgctgattctcaatgagctggttcggatcagcagcatggagggagag
cgcctgagagaagaaatggaagaaatcacacagcagcagttggtccatgacaagtactgc
aaggatctcatgggttttggaacgaaaccccgtcacatcacccccttcaccagtttccag
gccatgcagccccagcagtccaatgccttggtggggctgctggggtacagctctcaccaa
ggcctcatgggcttcggggcctcccccagcccagcaaagtccacgctggtggagagtcgc
tgctgcagggacttgatggaggagaaatttgatcaggtgtgccagtgggtcctgaagtgc
aggaatagcaagaactcgctgatccaaatgacaatccttaatttgttgccccgcttggct
gccttccgaccttctgccttcacagatacccagtacctccaggataccatgaaccatgtc
ctgagctgcgtcaagaaggagaaggaacggacagcagcctttcaagccctggggctactt
tctgtggctgtgaggtctgagttcaaggtctatttgcctcgtgtgctggacattatccga
gcagccctgccccctaaggacttcgcccataagagacagaaggctatgcaggtggatgcc
acggtgttcacctgcatcagcatgctggcccgagccatggggccaggcatccaacaggac
atcaaggagctgctggagcccatgctggcagtgggcctgagccctgccctcacagctgtg
ctctacgacctgagccgtcagattccacagctgaaaaaggacatccaagatgggctcctg
aagatgctgtccctggtccttatgcacaaacccctccggcacccaggcatgcccaagggc
ctggcccatcagctggcttcccctggcctcacgaccctccctgaggccagtgatgtgggc
agcatcacccttgctctccgaactctcggcagttttgaatttgaaggccactctctgacc
cagtttgtccgccactgtgcggatcacttcctgaacagcgagcacaaggagatccgtatg
gaggccgcccgcacctgctcccgcctgctcacgccctctgtccacctcatcagtggccac
gctcatgtggtcagccagactgcagtgcaagtggtggcagatgtactcagcaaactgctt
gtggttgggataactgatcctgaccccgacatccgctactgtgtcttggcgtccctggac
gagcgctttgacgcacacctggcccaggcggagaacctgcaggccctgttcgtggctctg
aatgaccaggtgtttgagatccgggagctggccatctgcactgtgggccggctcagcagc
atgaacccagcctttgtcatgcccttcctgcgcaagatgctcatccagattctgacagag
ctggagcacagcggcattggaagaatcaaggagcagagtgcccgcatgctgggccacctg
gtctccaacgccccgcgactcatccgcccatacatggagcctattctgaaggctttaatt
ttgaaactgaaagatccagaccctgatccaaacccaggtgtgatcaataatgtcttggct
acaataggagagttggctcaggttagtggcctcgaaatgaggaaatgggttgatgaactt
tttattatcatcatggacatgctccaagactcctctctgttggccaaaaggcaggtggct
ctgtggaccctggggcagttggtggccagcaccggctacgtggtcgagccctacaggaag
taccccacgttgctggaggtgctgctgaactttctgaagactgagcagaaccagggtaca
cggcgggaggctatccgtgtgttggggcttctaggggcactggatccctacaagcacaaa
gtgaacattggcatgatcgaccagtcccgggacgcttctgccgtcagcctgtcagagtcc
aagtcaagtcaagattcttctgactacagcaccagcgagatgctggtcaacatggggaac
ctgcctctagacgagttctacccggccgtgtccatggtggccctgatgcgcatcttccga
gaccagtccctctctcaccaccacaccatggtcgtccaggccatcaccttcatcttcaag
tccctggggctcaagtgcgtgcagttcctgccccaggtcatgcccacattcctgaatgtc
attcgggtttgtgacggggccatccgggaatttttgttccagcagctgggaatgttggtg
tcctttgtgaagagccacatcagaccttacatggatgagatagtcacgctcatgagagaa
ttctgggtcatgaacacctccatccagagcacaatcattctcctcattgagcagattgtg
gtagccctcgggggtgaatttaagctctacctgccccagctgattccacacatgcttcgt
gtcttcatgcatgacaatagctcaggccgcatcgtctccatcaagttgctggctgcaatc
cagctgttcggtgccaacctggacgactatctgcatttgttgctgcccccgatcgtgaag
ttatttgatgcccccgaagccccattgccttctcgaaaggccgcgctagagaccgtggac
cgtctgacggagtctctggatttcacggactatgcctctcggatcattcatcctattgta
cgcacactggaccagagcccagaactccgttccacagcaatggacacattgtcttcactc
gtctttcagctgggaaagaagtaccaaattttcattccaatggtgaacaaagttctggtg
agacaccgaatcaaccatcagcgctacgacgtcctcatctgcaggatagtcaaggggtat
accctagctgacgaggaggaggaccctctggtttaccagcatcgaatgctgaggagcggc
caaggtgatgccttagccagtggaccagtggaaacggggcccatgaagaagctgcacgtc
agcaccatcaacctccaaaaggcctggggagctgccagaagggtttccaaagatgattgg
ttggaatggctgcggcggctgagcctggagctgctgaaggactcctcgtcaccctccctg
cgctcctgctgggccctggcacaggcctacaacccgatggccagggatctctttaatgct
gcatttgtgtcctgctggtctgagctgaatgaggaccagcaggatgagctcatcagaagc
atcgagttggccctcacctcccaggacatcgcagaagtcacgcaaaccctcttaaatttg
gctgaattcatggaacacagtgacaagggccccctgcctttgagagatgacaatggcatt
gtcctgctgggcgagagggctgccaagtgccgagcatatgccaaagcgctgcactacaaa
gaactggagttccagaaaggtcccacccccgccatcctcgagtctctcatcagcattaat
aataagctgcagcagccagaggcagctgctggggtgttggagtatgccatgaagcacttt
ggagagctggagatccaggctacctggtatgagaagctgcacgagtgggaagatgctctc
gtggcctatgataagaaaatggacaccaacaaggacgacccagagctgatgctgggccgc
atgcgctgcctcgaggccttgggggaatgggggcagcttcaccagcagtgctgtgaaaaa
tggactctggttaatgatgagacccaagccaagatggcccgcatggctgctgcagctgca
tggggtttaggtcagtgggacagcatggaagagtacacctgtatgatccctcgggacacc
cacgatggggcattttatagagctgtgctggcactacatcaggacctcttctccttggca
caacagtgcatcgacaaagcccgggacctactggatgcagagttaacggcgatggcggga
gagagctacagccgggcctatggggccatggtttcttgccacatgctgtctgagctggag
gaggttatccagtacaaacttgtccctgagcgacgggagatcatccgccagatctggtgg
gagagactgcagggctgccagcgtattgtggaggactggcagaaaatcctcatggtgcgg
tcactcgtcgtcagccctcatgaggacatgaggacttggctcaagtacgcaagcctgtgt
ggcaagagtggcaggctggcgcttgctcacaaaaccttagtgctactcctgggagttgat
ccatctcggcaacttgaccatcctctgccaacagttcacccccaggtgacctacgcctac
atgaaaaatatgtggaagagcgcccgcaagattgacgccttccagcacatgcagcacttt
gttcagaccatgcagcagcaagcccagcatgccatcgccaccgaggaccagcagcacaag
caggagctgcataagctcatggcccgatgtttcctgaagctcggggagtggcagctgaac
ctacagggcatcaatgagagcacaatccccaaagtcctgcagtactatagcgccgccaca
gagcacgaccgcagctggtacaaggcctggcatgcgtgggcagtgatgaactttgaggct
gtgctccactacaaacatcagaaccaagcccgcgatgagaagaagaagctgcgacatgcc
agtggggccaacatcactaacgcggccactgctgccaccacagcagccacggccaccgcc
accgccaccagcaccgagggcagcaacagcgagagtgaggctgagagcaccgagaacagc
cctaccccatctcctttgcagaagaaggtcaccgaggatttgtctaaaaccctcttgatg
tacactgtccctgctgtccagggcttcttccgttccatctccttgtcacgaggcaacaac
ctccaggacacactcagagttctcaccttatggtttgattatggtcactggccagatgta
aatgaagccttagtggaaggggtgaaagcaatccagattgacacttggttacaggttata
cctcagctcattgcaagaattgatacgccgaggcccctggtgggacgtcttatccaccag
cttctcacagacattggtcggtaccacccccaggccctcatctacccgctgacagtggcc
tccaagtccaccaccacggcccggcacaacgcagccaacaaaatcctgaagaacatgtgc
gaacacagcaacaccctggtgcagcaggccatgatggtgagtgaggagctgatccgagtg
gccatcctctggcacgagatgtggcatgaaggcctggaagaggcatctcgcttgtacttt
ggggagaggaacgtgaaaggcatgttcgaggtgctggagcccctgcacgccatgatggag
cggggaccccagacactgaaggaaacatcatttaaccaggcatatggtcgagatttaatg
gaggcccaggaatggtgcaggaagtacatgaaatcagggaacgtcaaggacctcacccaa
gcctgggacctctattaccatgtattcagacgaatctccaagcagctgcctcagctcaca
tccttagagctgcagtacgtctcccctaaacttctgatgtgccgggatctggaactggct
gtgccgggaacttatgaccccaaccagcccatcattcgcattcagtccattgcgccatct
ctgcaagtcatcacatccaagcagaggccccggaagctgacgcttatgggcagcaacggg
cacgagtttgtcttcctcctgaagggccatgaggacctgcggcaggacgaacgggtgatg
cagctcttcggcctggtcaacacccttctggccaatgacccaacgtctcttcggaaaaac
ctcagcatccagagatacgctgtcattccattatcaaccaactcgggcctcatcggctgg
gtgccccactgtgacacgctgcacgccctcatccgggactacagggagaaaaagaagatc
cttctcaacattgagcatcgcatcatgctgcggatggctccggactatgaccatctaact
ctgatgcagaaggtcgaggtgtttgagcacgctgtcaacaacacagctggggatgacctg
gccaaactgctgtggctgaaaagccctagctccgaggtgtggtttgatcgaagaaccaat
tatacccgctctttagcagtcatgtctatggttgggtatattttgggcctgggcgataga
catccatccaacctgatgctggaccggctgagtggaaagattctgcacattgactttggg
gactgctttgaggttgctatgaccagagagaaattcccagagaagattccatttagacta
acgagaatgctgaccaatgctatggaggtcacgggccttgatggcaactacaggatcacg
tgccacaccgtgatggaggtgctccgggagcacaaggacagcgtcatggctgtgctggaa
gccttcgtctatgaccccctgctgaactggaggctgatggacacaaataccaaaggtaac
aagcgatcacggacaaggaccgattcctactctgctggccagtcagtagaaattttggat
ggtgtggaacttggggaaccagcccataagaaaacagggaccacggtgccagaatctatt
cattctttcattggagatggtttggtgaaaccagaggccctaaataagaaagctattcaa
attattaacagggttcgagataaactcactggtcgggacttctctcatgacgaaaccctg
gatgtcccaacacaagtcgagctgctcatcaaacaagcgacatcccatgaaaacctctgc
cagtgctacattggctggtgtcctttctggtaa |
|---|
