Carlito syrichta (Philippine tarsier): 103250948
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Entry
103250948 CDS
T07836
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr04217
Necroptosis
csyr04380
Osteoclast differentiation
csyr04620
Toll-like receptor signaling pathway
csyr04621
NOD-like receptor signaling pathway
csyr04630
JAK-STAT signaling pathway
csyr04658
Th1 and Th2 cell differentiation
csyr04659
Th17 cell differentiation
csyr05145
Toxoplasmosis
csyr05160
Hepatitis C
csyr05161
Hepatitis B
csyr05162
Measles
csyr05164
Influenza A
csyr05165
Human papillomavirus infection
csyr05167
Kaposi sarcoma-associated herpesvirus infection
csyr05168
Herpes simplex virus 1 infection
csyr05169
Epstein-Barr virus infection
csyr05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103250948 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
103250948 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
103250948 (TYK2)
04621 NOD-like receptor signaling pathway
103250948 (TYK2)
04658 Th1 and Th2 cell differentiation
103250948 (TYK2)
04659 Th17 cell differentiation
103250948 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
103250948 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
103250948 (TYK2)
05160 Hepatitis C
103250948 (TYK2)
05171 Coronavirus disease - COVID-19
103250948 (TYK2)
05164 Influenza A
103250948 (TYK2)
05162 Measles
103250948 (TYK2)
05168 Herpes simplex virus 1 infection
103250948 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
103250948 (TYK2)
05169 Epstein-Barr virus infection
103250948 (TYK2)
05165 Human papillomavirus infection
103250948 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103250948 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
csyr01001
]
103250948 (TYK2)
Enzymes [BR:
csyr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103250948 (TYK2)
Protein kinases [BR:
csyr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103250948 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Jak1_Phl
FERM_F2
PK_Tyr_Ser-Thr
FERM_F1
SH2_1
Pkinase
Motif
Other DBs
NCBI-GeneID:
103250948
NCBI-ProteinID:
XP_021563972
Ensembl:
ENSTSYG00000028862
UniProt:
A0A3Q0DNG1
LinkDB
All DBs
Position
Unknown
AA seq
815 aa
AA seq
DB search
MPFCQWKAARSSKPNEDVAQPMAAVGDLKVLLHWAGPGGGEPWVTFSEASLTAEEVCIHI
AHKVGISPPCFNLFALFDAQAQVWLPPNHVLETSRDTSLVLYFRMRFYFRNWHGTNPQEP
TVYRCGPPGTEASSDPTEQGMQLLDSASFEYLFEQGKHEFVNDVASLSELSSEEEIHHFK
NESLGMAFLHLCHLALHRGVPLEEVAKKISFKDCIPRSFRLQIRQHSTLTRLRLRSMFRS
FLRAFQPGRLSQQVVMVKYLATLERLAPRFGTECVSVCHLQLLAQAEAGSCCVQDSRQAP
VDPSSKTAARPLTHEVLVTGTGGIQWRPVWEVRGSTSSSGAGRNPQADLFGKSAKVPEAG
GQSVARPREPPWTYFCDFRDITHVVLKECRVGIHRQDNKCLELGLPSRAAALSFVALVDG
YFRLTADSSHYLCHEVVPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHLHR
LILTVAQRGPDQSLRLRKFPIEQRAGAFVLEGWGRPFPSVRELRATLQGCSLRARDDCFS
LRCCCLPRPGEISNLIITWGPRASGRPLNLSQLTFHRVGHNEITQRSHLGQGTRTNVYEG
LLRVEGGGPEEGTVDSGDTLVPGGDREQELRVVLKVLDPSHHNIALAFYETASLMSQVSH
AHLAFVHGVCVRGPENIMVTEYVEHGPLDMCLRRERGRVPVAWKLAVAQQLASALSYLED
KSLVHGNVCGRNILLARLGLSEGTSPFIKLSDPGVGLCALSREEQIERIPWLAPECLLVG
ASSLSTATDKWGFGASLLEICFDGEVPLQGCGPSE
NT seq
2445 nt
NT seq
+upstream
nt +downstream
nt
atgccattctgtcagtggaaggccgccaggagcagcaagcccaacgaggacgtagctcag
cccatggctgctgtgggagacctgaaggtgcttctgcactgggccgggcctggtggtggg
gagccctgggtgaccttcagtgaggcctcgctgaccgccgaggaggtctgcatccacatt
gcacacaaagtcggcatctctcctccctgcttcaatctcttcgccctctttgacgcccag
gcccaggtctggttgcccccaaaccacgtcctggagacctccagagacacaagcttggtg
ctgtatttccgcatgaggttttacttccggaactggcatggcacgaatcctcaggagccg
actgtgtaccgctgtgggcccccaggaactgaggcgtcctcagacccgacagagcagggc
atgcagctcctggactcagcctcttttgagtacctcttcgagcagggcaagcatgagttt
gtgaacgatgtggcatcactgtcagagctgtcgagcgaggaggagattcaccacttcaag
aacgagagcctgggcatggcctttctgcacctctgccacctagctctccaccgtggcgtc
cccctggaggaagtggccaagaagatcagcttcaaggactgtatcccccgttccttccgg
ctgcagatccggcagcacagcaccctgacgcggctgcgcctgcggagcatgtttcgtagt
ttcctgcgggccttccagccgggccgtctctcccagcaggtggtcatggtcaagtacctg
gccacgctggagcggctggcgccccgcttcggcacagagtgtgtgtccgtgtgccacctg
cagctgctggcccaggccgaggcggggtcctgctgcgtccaggacagcaggcaggcccct
gtggatcccagctccaagaccgctgccaggcccctgacccacgaagtgctggtgaccggt
acaggtggcatccagtggcggccagtgtgggaggtgaggggttccaccagtagcagcggc
gctggcaggaatccccaagctgacctgtttggaaagagcgccaaggtacctgaggcaggt
ggccagtcagtggccaggccacgggagccaccctggacctacttctgtgacttccgggac
atcacccacgtggtgctgaaggagtgccgtgtcggcatccaccggcaggacaacaagtgt
ctggagctgggcctgccctcccgtgctgctgccctgtctttcgtggccctggtggatggc
tatttccgtctgacggctgactccagccactacctgtgccatgaggtggtgcctccccgg
ctggtgatgagcatccgggatggcatccacggacccctgttggagccgtttgtgcaggcc
aagctgcggccggaggacggtctctaccttatccactggagcaccagccacctccaccgg
ctgatcctcacggtggcccagcgtggcccggaccagagcctgcgtctccgcaagttcccc
attgagcagcgcgctggcgccttcgtgctggagggctggggccggcctttccccagtgtg
agggagctgcgagccaccctacagggctgctcgctgcgtgccagagatgactgcttctcc
ctgcgctgctgctgcctgccccggccgggagagatctccaacctcatcatcacatgggga
cctcgggcaagcggcaggccgctcaacctcagccagctcaccttccatcgggtgggccac
aacgagatcacccagcggtcccacctgggtcagggcacgaggaccaacgtgtacgaaggc
ctcctgcgagtggagggcgggggccccgaggagggcacggtggacagcggggacaccctg
gtacctggtggggatcgtgagcaggagctccgcgtggtgctcaaagtgctggaccctagt
caccacaacattgctctggccttctacgagacagccagcctcatgagccaggtctcccac
gcacacctggccttcgtgcatggcgtctgcgtgcgcggccctgagaacatcatggtgacg
gagtatgtggaacatgggcccctggacatgtgtctgcggcgagagcggggccgcgtgccc
gtggcctggaagttggctgtggcccagcagctggccagcgccctcagctacctggaggac
aagagcctggttcacggtaatgtgtgtggccggaacattctactggcacgattggggctg
tcagaaggcaccagccccttcatcaagctgagcgaccccggcgtgggcctgtgtgccctc
tccagggaagagcagatcgagcggataccctggctggcacctgagtgcctgctggttggg
gccagcagtctgagcactgccaccgacaagtggggctttggtgccagcctcctggagatc
tgctttgacggggaggtgcccctgcagggctgcggcccctctgag
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