Carlito syrichta (Philippine tarsier): 103251030
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Entry
103251030 CDS
T07836
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr01521
EGFR tyrosine kinase inhibitor resistance
csyr01522
Endocrine resistance
csyr01524
Platinum drug resistance
csyr04010
MAPK signaling pathway
csyr04012
ErbB signaling pathway
csyr04020
Calcium signaling pathway
csyr04066
HIF-1 signaling pathway
csyr04151
PI3K-Akt signaling pathway
csyr04510
Focal adhesion
csyr04520
Adherens junction
csyr04530
Tight junction
csyr05200
Pathways in cancer
csyr05205
Proteoglycans in cancer
csyr05206
MicroRNAs in cancer
csyr05212
Pancreatic cancer
csyr05213
Endometrial cancer
csyr05215
Prostate cancer
csyr05219
Bladder cancer
csyr05223
Non-small cell lung cancer
csyr05224
Breast cancer
csyr05226
Gastric cancer
csyr05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103251030 (ERBB2)
04012 ErbB signaling pathway
103251030 (ERBB2)
04066 HIF-1 signaling pathway
103251030 (ERBB2)
04020 Calcium signaling pathway
103251030 (ERBB2)
04151 PI3K-Akt signaling pathway
103251030 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103251030 (ERBB2)
04520 Adherens junction
103251030 (ERBB2)
04530 Tight junction
103251030 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103251030 (ERBB2)
05206 MicroRNAs in cancer
103251030 (ERBB2)
05205 Proteoglycans in cancer
103251030 (ERBB2)
05230 Central carbon metabolism in cancer
103251030 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
103251030 (ERBB2)
05226 Gastric cancer
103251030 (ERBB2)
05219 Bladder cancer
103251030 (ERBB2)
05215 Prostate cancer
103251030 (ERBB2)
05213 Endometrial cancer
103251030 (ERBB2)
05224 Breast cancer
103251030 (ERBB2)
05223 Non-small cell lung cancer
103251030 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103251030 (ERBB2)
01524 Platinum drug resistance
103251030 (ERBB2)
01522 Endocrine resistance
103251030 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
csyr01001
]
103251030 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
csyr04147
]
103251030 (ERBB2)
04090 CD molecules [BR:
csyr04090
]
103251030 (ERBB2)
Enzymes [BR:
csyr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103251030 (ERBB2)
Protein kinases [BR:
csyr01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
103251030 (ERBB2)
Exosome [BR:
csyr04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
103251030 (ERBB2)
CD molecules [BR:
csyr04090
]
Proteins
103251030 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Protocadherin
Kinase-like
CRIM1_C
Stevor
RIFIN
Motif
Other DBs
NCBI-GeneID:
103251030
NCBI-ProteinID:
XP_021564028
Ensembl:
ENSTSYG00000027118
UniProt:
A0A3Q0DQC5
LinkDB
All DBs
Position
Unknown
AA seq
1225 aa
AA seq
DB search
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPASASLSFLQDIQEVQGYVLIAHNQ
VRRVPLQRLRIVRGTQLFKDNYALAVLDNGDLPNNATPATRASPGGLQELQLRSLTEILK
GGVLIQRNPQLCYQDMILWQDIFHKNNQLPLMQIDTNRSRACRPCSPACKASHCWGESSE
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA
LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHDQEVTAEDGTQR
CEKCSKPCARVCYGLGMEQLREARAVTSDNIQEFAGCKKIFGSLAFLPQSFDGNPASNTA
PLRPEQLRVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRVLHDGAYSLTLQGLNI
SWLGLRSLRELGSGLALIHRNARLCFVHTVPWNQLFRTSHQALLHTANRPENECVGQGLA
CYPLCAQGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ
NGSVTCFGSEADQCVACARYKDPPFCVSRCPSGVKPDLSYMPIWKFPDEEGTCQPCPINC
THSCVDLDDKGCPAEPRASSLTSIISAVVGIMLVVVLAIVFVILIKRRQQKIRKYTMRRL
LQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPV
AIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHV
REHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL
DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPARE
IPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQ
NEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGSTAHHRHRSS
STRSGGGDLTLGLETTEEEAPRSPLAPSEGTGSDVFDGDLGIGAAKGLQSLPPHDPSPLQ
RYSEDPTAPLPPETDGYIAPLTCSPQPEYVNQPDVWLQPASPREGTLPPAQPAGATLERP
KTLSPGKNGVVKDVFAFGGAVENPEYLAPQGGTAPQSHPPPAFSPAFDNLYYWDQDPSER
GSPPGTFEGTPTAENPEYLGLDIPV
NT seq
3678 nt
NT seq
+upstream
nt +downstream
nt
atgaagctacgcctccccgccagtcccgagacccacctggacatgcttcgccacctctac
cagggctgtcaggtggtgcagggtaacctggaactcacctacctgccggccagtgccagc
ctctccttcctgcaggatatccaggaggtgcagggctatgtgctcatcgcccacaaccaa
gtgaggcgggtcccgctgcagaggctgcggatcgtgcgaggtacccagctcttcaaggac
aactatgccctggccgtgctggacaatggagacctaccgaacaatgccacccctgccaca
agggcctccccaggagggctgcaggagctgcagcttcgaagcctcacagagatcctgaag
ggaggagtcttgatccagcggaacccccagctctgctaccaggacatgattctgtggcag
gacatcttccacaagaacaatcagctgcctctcatgcagatagacaccaaccgctcacgg
gcctgccgcccctgttctccagcttgtaaagcctcccactgctggggagaaagttccgag
gactgtcagagcttgacgcgtaccgtttgtgctggtggctgtgcccgctgcaagggcccg
ctgcccactgactgttgccatgagcagtgtgctgctggctgcacgggccccaagcactct
gactgcctggcctgcctccacttcaaccacagcggcatctgtgagctgcactgcccagcc
ctggtcacctacaacacggacaccttcgagtccatgcccaaccctgagggccggtataca
ttcggtgccagctgtgtgactgcctgtccctacaactacctatctacggacgtggggtcc
tgtaccctggtctgccccctgcacgaccaagaggtaactgctgaggacggtacacagcgg
tgtgagaagtgcagcaagccctgtgcccgagtgtgctatggtctgggcatggagcaattg
cgagaggccagggcggtcaccagcgacaatatccaggagtttgctggctgcaagaagatc
tttggaagcctggcatttctgccacagagctttgatgggaacccagcctccaacactgcc
ccgctacggccagaacagctccgagtatttgagactctggaggagataacagggtacctg
tacatctccgcatggccagacagccttcctgacctcagtgtattccagaaccttcaagtt
atccggggacgagttctgcatgatggtgcctactcgctgaccctgcaaggtctgaacatc
agctggctgggactgcgctcgctgcgggaactgggcagtggactggcccttatccaccgc
aacgcccgtctctgctttgtacacacggtgccctggaaccagctcttccggacctcgcac
caagccctgctccatactgccaatcggccagagaacgagtgtgtgggccagggcctggcc
tgctacccactgtgtgcccaagggcactgctggggtccggggcccacccagtgcgtcaac
tgcagccagttccttcggggccaggagtgcgtggaggaatgtcgagtactgcaggggctc
cccagggagtatgtgaatgccagacactgtctaccatgccaccctgagtgtcaaccccag
aatggctcagtgacctgttttggatcggaggctgaccagtgtgtggcctgtgcccgctac
aaggatcctcccttctgtgtgtctcgctgccccagcggtgtgaaacctgacctttcctac
atgcccatctggaagttccctgatgaggagggcacgtgccaaccatgccccatcaactgc
acccactcctgtgtggacctggacgacaagggctgccctgccgagccgagagccagctct
ctgacatccatcatctctgccgtggtgggcattatgctggttgtggtcctggcgatcgtc
ttcgtgatcctcatcaagcgacggcagcagaagatccggaagtatacgatgcggaggctg
ctgcaggagacggagctggtggagccactgacgcccagtggagcaatgcccaatcaggct
cagatgcggatccttaaagagacggagctgaggaaggtgaaggtgcttggatctggagct
ttcggcacagtctacaagggcatctggatccctgatggggagaatgtgaaaatcccagtg
gccatcaaagtgttgagggaaaacacatccccgaaagccaacaaagaaatcttggacgag
gcatacgtgatggctggtgtgggctccccgtacgtctcccgcctcctgggcatctgcctg
acatccacagtgcagctggtgacgcagctcatgccctatggctgcctcctagaccatgtc
cgggaacaccgcgggcgcctgggctcccaggacctgctgaactggtgtgtgcagattgcc
aaggggatgagctacctggaggacgtgcgacttgtgcacagggacctggctgctcggaat
gtgctggtcaagagtcccaaccacgtcaagattacagacttcgggctggctcggctgctg
gacattgacgagacagagtaccatgcagatgggggcaaggtacccatcaagtggatggcg
ttggagtccattctccgccggcggttcacccaccagagtgacgtgtggagttacggtgtg
actgtgtgggagctgatgacttttggggccaaaccttatgatgggatccctgcccgggaa
atccctgacctgttggagaagggggagcggcttccccagccccccatctgcaccatcgat
gtctacatgattatggtcaaatgttggatgattgactctgaatgtcggccgagattccgg
gagttggtggccgaattctcccgcatggccagggacccccagcgctttgtggtcatccag
aatgaggacttgggcccagccagccccttggacagtaccttctaccgctcactgctggag
gatgacgacatgggggacctggtggatgccgaggagtatctggtaccccagcagggcttc
ttctgcccagaccctgccccgggcgccgggagcacagctcaccacaggcaccgcagctca
tccactaggagtggtggtggtgacctgacgctggggctagagaccactgaagaggaggcc
cccaggtccccactggcaccctccgaagggactggctccgatgtgtttgatggtgacctg
ggaataggcgcagccaaggggctgcaaagcctccccccacatgaccccagccctctacag
cggtacagcgaagaccccacagcacccctgccccctgagactgatggctacattgccccg
ctgacctgcagcccccagcccgaatatgtgaaccaaccagatgtttggctgcagcccgcc
tcgccccgagagggcactctgcctcctgcccaacctgctggtgccactctggaaaggccc
aagactctctccccagggaagaatggggttgtcaaggacgtttttgcctttgggggtgcc
gtggagaaccccgagtacctggcaccccaaggagggactgcccctcagtcccaccctcct
ccagccttcagcccagcctttgacaacctctattactgggaccaggacccatcagagcgg
gggtctccacctggcacctttgaagggacccctacagcagagaaccctgagtatctgggc
ttggacataccagtgtga
DBGET
integrated database retrieval system