KEGG   Carlito syrichta (Philippine tarsier): 103251416
Entry
103251416         CDS       T07836                                 
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase
  KO
K00512  steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
Organism
csyr  Carlito syrichta (Philippine tarsier)
Pathway
csyr00140  Steroid hormone biosynthesis
csyr01100  Metabolic pathways
csyr04913  Ovarian steroidogenesis
csyr04917  Prolactin signaling pathway
csyr04927  Cortisol synthesis and secretion
csyr04934  Cushing syndrome
Module
csyr_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
csyr_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
csyr_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
csyr_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:csyr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    103251416
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    103251416
   04917 Prolactin signaling pathway
    103251416
   04927 Cortisol synthesis and secretion
    103251416
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103251416
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:csyr00199]
    103251416
Enzymes [BR:csyr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.19  steroid 17alpha-monooxygenase
     103251416
    1.14.14.32  17alpha-hydroxyprogesterone deacetylase
     103251416
Cytochrome P450 [BR:csyr00199]
 Cytochrome P450, animal type
  CYP17 family
   103251416
SSDB
Motif
Pfam: p450 Chal_sti_synt_C
Other DBs
NCBI-GeneID: 103251416
NCBI-ProteinID: XP_021564209
VGNC: 82916
UniProt: A0A3Q0DI44
LinkDB
Position
Unknown
AA seq 262 aa
RCPESPYSGARHRGGWEAGRVTSPCRCGAGEPPGCCSLDEKHRSRTTLDILSDNQKGVAF
ADYGSHWQLHRKLVMATFALFKDGDQKLETIICQQIRPLCDMLATRSGQSVDLSLPLFLA
ITNVICLICFNSSYKDKDPEVQVIQTYNDGILDTLGRDSLVDLFPWLKIFPNKTLETLRN
CVKLRNHLLKKILEQYKGKFSSDSISNMLDVLIQARMNADNAGAAQDRGMLSDRHILATV
GDIFGAGVETTTSVVKWTVAFL
NT seq 787 nt   +upstreamnt  +downstreamnt
gaggtgcccagagagcccttattctggcgcccggcaccgcgggggctgggaagcaggccg
tgtcacgtccccatgccgctgcggcgcgggggagccgcctggctgctgctccctggacga
gaagcaccgctcacggaccactctggacatcctgtcggacaaccagaagggcgtggcctt
cgccgactatggctcacactggcagctgcaccggaagctggtgatggccaccttcgccct
tttcaaggacggcgaccagaagctggagacgatcatctgccagcaaatcaggccgctgtg
cgacatgctggccacccgcagcggacagtccgtggacctctccctgcctctcttcctggc
catcaccaacgtcatctgcctgatatgcttcaactcgtcctacaaggacaaggaccccga
ggtgcaggtcatccagacttacaacgacggcatcctggacacgctgggcagggacagcct
ggtggacctgtttccctggctgaagattttccccaacaaaacactggagacgttacggaa
ctgtgtcaagttacggaatcatctgctgaaaaaaatactggaacaatacaagggcaagtt
cagcagcgactccatcagcaacatgctggacgtgctgatccaggccaggatgaacgcgga
caacgccggcgccgcccaggaccgcgggatgctttccgacaggcacatcctggccaccgt
aggggacatcttcggcgccggcgtggagaccaccacctccgtggtcaagtggacggtggc
cttcctg

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