KEGG   Carlito syrichta (Philippine tarsier): 103254239
Entry
103254239         CDS       T07836                                 
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
csyr  Carlito syrichta (Philippine tarsier)
Pathway
csyr01521  EGFR tyrosine kinase inhibitor resistance
csyr01522  Endocrine resistance
csyr01524  Platinum drug resistance
csyr04010  MAPK signaling pathway
csyr04012  ErbB signaling pathway
csyr04014  Ras signaling pathway
csyr04015  Rap1 signaling pathway
csyr04022  cGMP-PKG signaling pathway
csyr04024  cAMP signaling pathway
csyr04062  Chemokine signaling pathway
csyr04066  HIF-1 signaling pathway
csyr04068  FoxO signaling pathway
csyr04071  Sphingolipid signaling pathway
csyr04072  Phospholipase D signaling pathway
csyr04140  Autophagy - animal
csyr04150  mTOR signaling pathway
csyr04151  PI3K-Akt signaling pathway
csyr04152  AMPK signaling pathway
csyr04210  Apoptosis
csyr04211  Longevity regulating pathway
csyr04213  Longevity regulating pathway - multiple species
csyr04218  Cellular senescence
csyr04261  Adrenergic signaling in cardiomyocytes
csyr04370  VEGF signaling pathway
csyr04371  Apelin signaling pathway
csyr04380  Osteoclast differentiation
csyr04510  Focal adhesion
csyr04550  Signaling pathways regulating pluripotency of stem cells
csyr04611  Platelet activation
csyr04613  Neutrophil extracellular trap formation
csyr04620  Toll-like receptor signaling pathway
csyr04625  C-type lectin receptor signaling pathway
csyr04630  JAK-STAT signaling pathway
csyr04660  T cell receptor signaling pathway
csyr04662  B cell receptor signaling pathway
csyr04664  Fc epsilon RI signaling pathway
csyr04666  Fc gamma R-mediated phagocytosis
csyr04668  TNF signaling pathway
csyr04722  Neurotrophin signaling pathway
csyr04725  Cholinergic synapse
csyr04728  Dopaminergic synapse
csyr04810  Regulation of actin cytoskeleton
csyr04910  Insulin signaling pathway
csyr04914  Progesterone-mediated oocyte maturation
csyr04915  Estrogen signaling pathway
csyr04917  Prolactin signaling pathway
csyr04919  Thyroid hormone signaling pathway
csyr04920  Adipocytokine signaling pathway
csyr04922  Glucagon signaling pathway
csyr04923  Regulation of lipolysis in adipocytes
csyr04926  Relaxin signaling pathway
csyr04929  GnRH secretion
csyr04931  Insulin resistance
csyr04932  Non-alcoholic fatty liver disease
csyr04933  AGE-RAGE signaling pathway in diabetic complications
csyr04935  Growth hormone synthesis, secretion and action
csyr04936  Alcoholic liver disease
csyr04973  Carbohydrate digestion and absorption
csyr05010  Alzheimer disease
csyr05017  Spinocerebellar ataxia
csyr05132  Salmonella infection
csyr05135  Yersinia infection
csyr05142  Chagas disease
csyr05145  Toxoplasmosis
csyr05152  Tuberculosis
csyr05160  Hepatitis C
csyr05161  Hepatitis B
csyr05162  Measles
csyr05163  Human cytomegalovirus infection
csyr05164  Influenza A
csyr05165  Human papillomavirus infection
csyr05166  Human T-cell leukemia virus 1 infection
csyr05167  Kaposi sarcoma-associated herpesvirus infection
csyr05168  Herpes simplex virus 1 infection
csyr05169  Epstein-Barr virus infection
csyr05170  Human immunodeficiency virus 1 infection
csyr05200  Pathways in cancer
csyr05205  Proteoglycans in cancer
csyr05207  Chemical carcinogenesis - receptor activation
csyr05208  Chemical carcinogenesis - reactive oxygen species
csyr05210  Colorectal cancer
csyr05211  Renal cell carcinoma
csyr05212  Pancreatic cancer
csyr05213  Endometrial cancer
csyr05214  Glioma
csyr05215  Prostate cancer
csyr05218  Melanoma
csyr05220  Chronic myeloid leukemia
csyr05221  Acute myeloid leukemia
csyr05222  Small cell lung cancer
csyr05223  Non-small cell lung cancer
csyr05224  Breast cancer
csyr05225  Hepatocellular carcinoma
csyr05226  Gastric cancer
csyr05230  Central carbon metabolism in cancer
csyr05231  Choline metabolism in cancer
csyr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
csyr05415  Diabetic cardiomyopathy
csyr05417  Lipid and atherosclerosis
csyr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:csyr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103254239
   04012 ErbB signaling pathway
    103254239
   04014 Ras signaling pathway
    103254239
   04015 Rap1 signaling pathway
    103254239
   04370 VEGF signaling pathway
    103254239
   04371 Apelin signaling pathway
    103254239
   04630 JAK-STAT signaling pathway
    103254239
   04668 TNF signaling pathway
    103254239
   04066 HIF-1 signaling pathway
    103254239
   04068 FoxO signaling pathway
    103254239
   04072 Phospholipase D signaling pathway
    103254239
   04071 Sphingolipid signaling pathway
    103254239
   04024 cAMP signaling pathway
    103254239
   04022 cGMP-PKG signaling pathway
    103254239
   04151 PI3K-Akt signaling pathway
    103254239
   04152 AMPK signaling pathway
    103254239
   04150 mTOR signaling pathway
    103254239
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103254239
  09143 Cell growth and death
   04210 Apoptosis
    103254239
   04218 Cellular senescence
    103254239
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103254239
   04550 Signaling pathways regulating pluripotency of stem cells
    103254239
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103254239
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103254239
   04613 Neutrophil extracellular trap formation
    103254239
   04620 Toll-like receptor signaling pathway
    103254239
   04625 C-type lectin receptor signaling pathway
    103254239
   04660 T cell receptor signaling pathway
    103254239
   04662 B cell receptor signaling pathway
    103254239
   04664 Fc epsilon RI signaling pathway
    103254239
   04666 Fc gamma R-mediated phagocytosis
    103254239
   04062 Chemokine signaling pathway
    103254239
  09152 Endocrine system
   04910 Insulin signaling pathway
    103254239
   04922 Glucagon signaling pathway
    103254239
   04923 Regulation of lipolysis in adipocytes
    103254239
   04920 Adipocytokine signaling pathway
    103254239
   04929 GnRH secretion
    103254239
   04915 Estrogen signaling pathway
    103254239
   04914 Progesterone-mediated oocyte maturation
    103254239
   04917 Prolactin signaling pathway
    103254239
   04926 Relaxin signaling pathway
    103254239
   04935 Growth hormone synthesis, secretion and action
    103254239
   04919 Thyroid hormone signaling pathway
    103254239
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103254239
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    103254239
  09156 Nervous system
   04725 Cholinergic synapse
    103254239
   04728 Dopaminergic synapse
    103254239
   04722 Neurotrophin signaling pathway
    103254239
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103254239
  09149 Aging
   04211 Longevity regulating pathway
    103254239
   04213 Longevity regulating pathway - multiple species
    103254239
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103254239
   05205 Proteoglycans in cancer
    103254239
   05207 Chemical carcinogenesis - receptor activation
    103254239
   05208 Chemical carcinogenesis - reactive oxygen species
    103254239
   05230 Central carbon metabolism in cancer
    103254239
   05231 Choline metabolism in cancer
    103254239
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103254239
  09162 Cancer: specific types
   05210 Colorectal cancer
    103254239
   05212 Pancreatic cancer
    103254239
   05225 Hepatocellular carcinoma
    103254239
   05226 Gastric cancer
    103254239
   05214 Glioma
    103254239
   05221 Acute myeloid leukemia
    103254239
   05220 Chronic myeloid leukemia
    103254239
   05218 Melanoma
    103254239
   05211 Renal cell carcinoma
    103254239
   05215 Prostate cancer
    103254239
   05213 Endometrial cancer
    103254239
   05224 Breast cancer
    103254239
   05222 Small cell lung cancer
    103254239
   05223 Non-small cell lung cancer
    103254239
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103254239
   05170 Human immunodeficiency virus 1 infection
    103254239
   05161 Hepatitis B
    103254239
   05160 Hepatitis C
    103254239
   05164 Influenza A
    103254239
   05162 Measles
    103254239
   05168 Herpes simplex virus 1 infection
    103254239
   05163 Human cytomegalovirus infection
    103254239
   05167 Kaposi sarcoma-associated herpesvirus infection
    103254239
   05169 Epstein-Barr virus infection
    103254239
   05165 Human papillomavirus infection
    103254239
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103254239
   05135 Yersinia infection
    103254239
   05152 Tuberculosis
    103254239
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103254239
   05142 Chagas disease
    103254239
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103254239
   05017 Spinocerebellar ataxia
    103254239
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103254239
   05418 Fluid shear stress and atherosclerosis
    103254239
   05415 Diabetic cardiomyopathy
    103254239
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103254239
   04932 Non-alcoholic fatty liver disease
    103254239
   04931 Insulin resistance
    103254239
   04933 AGE-RAGE signaling pathway in diabetic complications
    103254239
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103254239
   01524 Platinum drug resistance
    103254239
   01522 Endocrine resistance
    103254239
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:csyr01001]
    103254239
Enzymes [BR:csyr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103254239
Protein kinases [BR:csyr01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   103254239
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like PH FTA2 ABC1
Other DBs
NCBI-GeneID: 103254239
NCBI-ProteinID: XP_008050566
Ensembl: ENSTSYG00000011045
UniProt: A0A1U7T9U0
LinkDB
Position
Unknown
AA seq 374 aa
MKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSP
TSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKK
EVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRER
VFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAA
TMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILME
DIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKVGSL
YGMVCIYFGYSKMN
NT seq 1125 nt   +upstreamnt  +downstreamnt
atgaaaacagaacgaccaaagccaaacacgtttataatcagatgtctccagtggaccact
gttatagagagaacatttcatgtagatactccagaagaaagagaagaatggacagaagct
atccaggctgtagcagacagactgcagaggcaagaagaagagagaatgaattgtagtcca
acttcacaaattgataatataggggaggaagagatggatgcttctacaacccatcataaa
agaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttgggaaa
gttattttggttcgagagaaggcaagtggaaaatattatgccatgaagattctgaagaaa
gaagtcattattgcaaaggatgaagtggcacacacactaaccgaaagcagagtattaaag
aacactaggcatccctttttaacttccttgaaatattccttccagacaaaagaccgtttg
tgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagagcgg
gtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggactat
ctacattctggaaagattgtgtaccgtgatctcaagctggagaatttgatgctggataaa
gatggccacataaaaattacagactttggactttgcaaagaagggatcacagatgcagcc
accatgaagactttctgtggtacaccagaatacctggctcctgaggtgttagaagataat
gactatggccgagcagtagactggtggggcctaggggttgtcatgtatgaaatgatgtgt
gggaggttacctttctacaaccaggatcatgagaaactttttgaactaatactaatggaa
gacattaaatttcctcgaacactctcttcagatgcaaaatcgttgctttcagggctcttg
ataaaggatccaaataaacgccttggtggagggccagatgatgcaaaagaaattatgaga
cacagtttcttttctggagtaaactggcaagatgtatatgataaaaaggtaggctctctt
tatggcatggtttgtatatattttggctactctaaaatgaattaa

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