Carlito syrichta (Philippine tarsier): 103255688
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Entry
103255688 CDS
T07836
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103255688 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
csyr01002
]
103255688 (BACE1)
Enzymes [BR:
csyr01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
103255688 (BACE1)
Peptidases and inhibitors [BR:
csyr01002
]
Aspartic peptidases
Family A1: pepsin family
103255688 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
103255688
NCBI-ProteinID:
XP_008051842
Ensembl:
ENSTSYG00000003291
UniProt:
A0A1U7TFU3
LinkDB
All DBs
Position
Unknown
AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGSGVLPAQGTQLGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagccctgccctggctcctgctgtggatgggctcgggcgtgctgcccgcccag
ggcacccagctcggcatccggctgcccctgcgcagcggcctggggggcgcccccctgggg
ctgcggctgccccgggagaccgacgaggagcccgaggagcccggccggaggggcagcttt
gtggagatggtggacaacctgaggggcaagtcgggtcagggctactacgtggagatgacc
gtgggcagccccccgcagacgctcaacatcctggtggacacgggcagcagtaactttgca
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccggaagggcgtgtatgtgccctacacccagggcaagtgggaaggggag
ctgggcaccgacctggtgagcatcccccatggccccaacgtcactgtgcgtgccaacatc
gctgccatcactgaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
gggctggcctacgctgagattgccaggcccgacgactccctggagcccttctttgactcc
ctggtaaagcagacccacgttcccaacctcttctccctgcagctttgtggtgctggcttc
cccctcaatcagtcagaagtattggcttcagttggagggagcatgatcatcgggggtatc
gaccactcactgtacacgggcagtctctggtatacacccattcggcgggagtggtattat
gaggtaatcattgtacgggtggagatcaatggacaagatctgaaaatggactgcaaggag
tacaactatgacaaaagcatcgtggacagtggcaccaccaaccttcgtctgcccaagaaa
gtatttgaagctgcagtcaaatccatcaaggcagcctcctcgacggagaagttccccgat
gggttctggctaggagaacagctggtgtgctggcaagcaggcaccaccccttggaacatt
ttcccagtcatctcactctacctaatgggtgaggtcaccaatcagtccttccgcatcacc
atccttccacagcaatacttgcggccagtggaagatgtggccacgtcccaagatgactgt
tacaagtttgccatctcacagtcgtccacaggcactgtcatgggagctgttatcatggag
ggcttctacgttgtctttgaccgcgcccggaaacgaattggctttgctgtcagtgcttgc
catgtgcacgatgagttcaggacggcagcggtggaaggtccttttgtcaccccggacatg
gaagactgtggctacaacattccacagacagatgaatccaccctcatgaccatagcctat
gtcatggccgccatctgcgccctcttcatgctgccactctgcctcatggtgtgtcagtgg
cgctgcctccgctgcctgcgccatcagcacgatgactttgctgatgacatctccctgctg
aagtga
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